Background & Objective : Head trauma is one of the most common causes of death in accidents and it is irreversible. More than 10000 cases of brain death occur annually in Iran and less than 10% of them are donors. That is why the number of organ transplantation in Iran is much lower than Europe and America. This study was conducted to investigate the attitude of 20-60 year-old citizens of Tehran about organ donation in brain death.

  Methods : This cross-sectional study was performed on 730 subjects (384 females and 346 males ( in 2000. The questionnaire and multi-stage sampling methods were used to collect data. The data were analyzed using SPSS and Chi-square tests.

  Results : about 44% of the subjects believed that the brain death is virtually irreversible and 93% of these subjects agreed with transplantation. 88% of those who agreed with transplantation accepted to fill out special donation forms. Humanitarian considerations and heavenly rewards were two main reasons mentioned by these people.

  Conclusions : According to this study, it is necessary to train people in order to increase their knowledge regarding brain death and create a positive attitude about organ donation. meanwhile passing some laws in this regard which are in accordance with Islam is recommended.