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Showing 2 results for Troponin I

Bahman Bashardoost , Hosein Doostkami , Ziba Faalpoor , Khadige Eslamnegad, Ali Abedi ,
Volume 5, Issue 4 (12-2005)
Abstract

 Background & Objectives: Cardiovascular events are among the most common causes of mortality in patients with end stage renal disease. Caediac biomarkers such as troponins are very sensitive in diagnosing heart problems. Troponin I can be used to diagnose acute cardiovascular problems in hemodialysis patients.

 Methods: In this descriptive-analytical and cross-sectional study the level of troponin I was measured in 39 hemodialysis patients using ELISA method and BUN, Cr and Hb level before hemodialysis. LVH and LVMI were determined by echocardiography. The data were analyzed using SPSS.

 Results: The patients were 52.92 years old on average. 26 patients were male and 13 female. The average of tropnin I was 0.78 μ g/l. There was no meaningful relationship between troponin I and LV MI, age and sex. However, a significant relationship was found between the level of troponin I with EF and diastolic dysfunction (p=0.05).

 Conclusion: Troponin I can be regarded as an indicator of LV dysfunction.


Bahman Bashardoost , Shahram Habibzadeh, Anahita Zakeri , Neda Ghaemian ,
Volume 12, Issue 5 (11-2012)
Abstract

  Background & Objectives: Cardiovascular events are the most common cause of death in hemodialysis patients. Cardiac biomarkers and especially Cardiac troponin I has been used as a prognostic marker in hemodialysis patients and there is some controversies about its value. For these reasons this study has been done for evaluation of prognostic value of Troponin I and left Ventricular Hypertrophy in mortality of hemodialysis patients.

  Methods:This is a prospective descriptive-analytic study, has been done from 2006 -2011 All of new cases whom entered to dialysis center in 2006 studied with measurement of base line Cardiac Troponin I and left ventricular mass index .Patients fallowed up 5 years later without any specific intervention and survival rate was calculated crudely and in base of Cardiac Troponin I and left ventricular mass index separately after exclusion of non cardiac deaths.

  Results:76 patients followed up 5 years and 35 of them died. Mean age of patients was 57.4 ± 15.6 year. Mean Troponin I (cTnI) in dead patients was 0.92±0.68ng/l and in alive patients was 0.78±0.58ng/l (p=0.39). Mean Left Ventricular Mass in dead patients was 274.9±100.8 g/m2 and in alive patients was 249±77.7 g/m2 (p=0.23). A significant linear correlation was not founds between cTnI level and Left Ventricular Mass Age was the most important cofactor of death.

  Conclusion: Significant correlation was not founded between cTnI level and Left Ventricular Mass with cardiac mortality .mortality. This may be due to some other factors such as age, quality of control of hypertension and other coexisted diseases, quality of life and home cares. Age had more important effect on death and this may reflect multiplicity of heath related problems in them.



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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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