Background & Objective : The role of circulating lipids in the pathogenesis of ischemic stroke remains unclear despite 3 decades of research. Since ischemic stroke is one of the important causes of death or disability in the world. Finding its risk factors can play a crucial role in health interferences.This study was conducted to investigate the relationship between blood lipids and ischemic stroke.

  Methods : This was�a case-control study conducted in 2002. The case group were patients who were definitely diagnosed to have ischemic stroke for the first time. An equal number of control subjects (with the same age and sex) were selected from other hospital wards. These two groups were compared in terms of the blood lipids. The collected data were analyzed using SPSS software (release 12) and statistical methods such as ANOVA and multivariate regression.

  Results : In this research 132 cases were compared with equal number of control subjects. The subjects in both groups were 64.1 years old on average. The mean level of total cholesterol was significantly higher in case group (p=0.001). The mean level of Triglycerides had no significant difference in two groups.

  Conclusions: Regarding the findings of the present research, offering strategies to lower the chlestrol level through primary prevention as well as drug interferences especially in the groups with other risk factors of stroke, seems to have a significant role in the prevention of ischemic stroke.

  Background & Objectives: Plasma lipids during pregnancy clearly increase, therefore, normal pregnancy is considered as a hyperlipidemia state. Prior studies suggest that coronary artery diseases connected with parity, but no studies have examined the relationship between parity and lipid levels in Iran. In the current study we investigated the relation between parity and lipid levels in maternal plasma in 13-23 weeks pregnant women.

  Methods: This study was done on 700 pregnant women with 18-40 years old at their 13-23 weeks gestation. Gestational age was calculated by LMP and ultrasound in early pregnancy. After obtaining informed consent from patients without exclusion criteria of the study, TC, TG, HDL-C and LDL-C was requested for them. Finally, the samples of study divided three groups according to the number of parity: nuliparous , multiparous , Grand multiparous . Data were analysed by SPSS-16 software using ANOVA and partial correlation statistical test.

  Results: With the exception of TG that showed significance difference in mean (p=0.008), the means of LDL-C (p= 0.37), HDL-C (p= 0.09) and TC (p=0.15) were not statistically significant among the 3 studied groups. Partial correlation test indicated statistically significant relationship between HDL-C with parity.

  Conclusion: The results of this study indicate decreased HDL-C levels with increasing number of pregnancies. Thus offering the program education and adequate family planning services to women in reproductive age are strongly advised.