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Showing 2 results for Prognosis
Pegah Alempoor, Ata Mahmoodpoor, Kamran Shadvar, Ali Asghar Kheiri, Ali Akbar Ghamari, Parviz Saleh, Seied Hadi Saghaleini,
Volume 23, Issue 2 (7-2023)
Abstract
Background & Objectives: Early warning scores are commonly used by hospital care teams to assess patients and diagnose early signs of their deterioration and initiate further treatment. Due to the existing studies and the lack of sufficient evidence for burned patients, we decided to investigate the value of initial NEWS and MEWS in predicting mortality in burned patients.
Methods: After obtaining permission from the Ethics Committee of TUMS, patients who were candidates for hospitalization in the burn wards of Sina Hospital from July to March 1998 were included. All demographic information including age, sex, APACHE Type of discharge, comorbidities, percentage of burns, initial hospitalization in the burn ward, type and time of initiation and duration of antibiotic use, amount of serum and NEWS and MEWS scores for all patients were enrolled immediately after admission to the ward as well as before discharge from the ward. Data were analyzed after registration in SPSS software version 23.
Results: In this study, 80 cases of burned patients were studied with a mean age of 37.94±18.85 years. The initial NEWS and MEWS indices have a good ability to diagnose burned patients (Area=0.79 and 0.78, p<0.001). The best cut- point based on the Youden index, for the initial NEWS and MEWS indices were obtained at 4.50 and 1.50, respectively.
Conclusion: In this study, for the first time, NEWS and MEWS were examined in predicting mortality in burned patients and it was found that these criteria can predict the prognosis of burned patients.
Maryam Ekran, Atabak Sedigh-Namin, Effat Iranijam, Shafagh Aliasgarzadeh, Nazli Javaheri, Afshan Sharghi,
Volume 25, Issue 2 (7-2025)
Abstract
Background: Thrombocytopenia is a clinical manifestation of coronavirus disease 2019 (COVID-19), potentially leading to bleeding and affecting disease prognosis. This study aimed to compare the prevalence of thrombocytopenia in deceased and recovered COVID-19 patients admitted to the Intensive Care Unit (ICU) of Imam Khomeini Hospital, Ardabil.
Methods: This cross-sectional study was conducted on 458 patients with confirmed COVID-19 admitted to the ICU of Imam Khomeini Hospital from April to September 2021. After applying exclusion criteria, 403 patients (136 recovered and 267 deceased) were analyzed. Demographic, clinical, and laboratory data, including thrombocytopenia severity, were extracted from medical records and analyzed using statistical tests (e.g., Chi-square and logistic regression).
Results: Thrombocytopenia was observed in 18.4% (25 of 136 patients) of recovered patients and 76% (203 of 267 patients) of deceased patients. The mean age of patients with thrombocytopenia was significantly higher in the deceased group (70.27±13.62 years) compared to the recovered group (61.20±15 years) (p=0.001). Heart failure was significantly associated with thrombocytopenia (p=0.038). Patients treated with remdesivir showed higher thrombocytopenia prevalence in the recovered (84%) and deceased (65.2%) groups, but this was not statistically significant.
Conclusion: Older age and heart failure were associated with increased thrombocytopenia in deceased COVID-19 patients. Severe thrombocytopenia was linked to a higher mortality risk.
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