[Home ] [Archive]   [ فارسی ]  
:: Main In Press Current Issue All Issues Search register ::
Main Menu
Home::
Journal Information::
Editorial Board::
Articles archive::
For Authors::
For Reviewers::
Editorial Policy::
Registration::
Contact us::
::
..
Indexing

 

 

 

 

 
..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Creative commons

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

..
:: Search published articles ::
Showing 8 results for Pneumonia

Manoochehr Barak , Nayereh Aminisani , Nategh Abbasgholizadeh , Mehrdad Mirzarahimi ,
Volume 4, Issue 2 (6-2004)
Abstract

 Background & Objective: Each year thousands of children under five years old die due to acute respiratory infection and diarrheal diseases. A huge number of infants and children are hospitalized and visited by the physicians whereas most of these diseases can be prevented with timely treatment. Child health maintenance and improvement is one of the most important considerations in each society. Moreover, identifying child morbidity patterns should be a matter of concern in order to improve the health services. This study provides an overview of the leading causes of hospitalization among children with the aim of determining the most important causes of hospitalization and offering appropriate strategies to decrease them.

 Methods: This cross-sectional study was conducted in 2001 in Ardabil Ali-Asghar hospital. The subjects were randomly selected from the admission list on a daily basis. A questionnaire including demographic characteristics such as age, sex, time of admission and primary diagnosis was completed for each subject. The data were analyzed by SPSS software using descriptive statistics.

 Results: A total of 1945 patients were admitted almost half of which were studied. Febrile convulsion was found to be the most common cause of hospitalization (26%) while gastroenteritis (22.1%) and pneumonia (20%) were in the second and third order. Other causes included epilepsy, drug poisoning, meningitis, mumps, drug encephalitis, asthma, etc.

 Conclusion: According to the findings of this study, standard case management is necessary especially about febrile convulsion which is the most common cause of hospitalization. Since the present pattern is different from similar studies, further investigations are required to identify its causes.


Ahmad Hashemzadeh, Farhad Heidarian,
Volume 5, Issue 2 (6-2005)
Abstract

  Background & Objectives: Respiratory distress is one of the most important causes of children admission in hospitals. In most cases, it is due to pneumonia, asthma or acute bronchiolitis. Since theses diseases have a lot of symptoms in common, we decided to study these disorders in more details to facilitate the appropriate diagnosis and treatment based on clinical, laboratory and radiologic findings.

  Methods: 238 children who suffered from respiratory distress and were admitted to pediatric ward in Ghaem hospital were studied. This descriptive study was performed during 3 years including 2 retrospective and one prospective year. The relationship between variables was analyzed using chi-square test.

  Results: The patients were six months to five years old. Pneumonia (40.3%) asthma (30.3%) and bronchiolotis (16.8%) were the most common causes of respiratory distress. Totally, 61.1% of the patients were male. The mean age of the patients was 10.3 months in bronchiolitis and 36.6 months for asthma. The most common symptom among these three diseases was tachypnea. Most of the patients were admitted in winter and fall respectively. The main radiologic pattern in pneumonia was pulmonary infiltration and for asthma and acute bronchiolitis it was pulmonary hyperinflation.

  Conclusion: Proper attention to signs and symptoms as well as laboratory and radiologic fndings is necessary for accurate diagnosis. In this study the most common cause of respiratory distress in children under 5 was found to be pneumonia, asthma and bronchiolitis respectively.


Adalat Hosseinian , Shahram Habibzadeh , Saeid Sadegieh Ahari , Akbar Mokhtarpoor,
Volume 7, Issue 1 (4-2007)
Abstract

  Back grounds and objectives : Arthrosclerosis is the major cause of cerberovascular disorders and major problems of industrial countries. Mortality from chronic diseases such as arthrosclerosis and mortality from infectious diseases have a reverse, relationship with economic and educational levels of people. For this reason, investigating the relationship of MI with other risk factors such as infections has been of great interest.

  Methods: This was a case- control study. 60 patients with MI and 60 matched cases were selected from other wards of Boali Hospital. All of the patients who had been admitted with myocardial infarction diagnosis in the time of study were selected and information about them was recorded in a researcher made questionnaire. Serum sample from patients and control case were sent to determinations of IgG Anti Chlamydia antibodies with enzyme immune assay. Control case were selected from other wards of hospital who matched in age, sex and same test in serum sample was done.

  Results: In this study in each group 48 persons (80%) were male and 12 persons (20%) were female. The range of age group was 35-80. Mean age group was 58.83±12.6 (SD) and mean age of control tools was 59.08±11.59.All of the patients in each group had anti Chlamydia antibodies (IgG) (titer more than 5U/ml). The mean range IgG in both groups were compared through t-test and there was no significant difference between them (p=0.85).

  Conclusion: In this study all of the cases and controls had anti Chlamydia antibodies. (IgG) high prevalence due to cold climate and high crowd of people in this area may be related to Chlamydia infection.


Ahmad Ghasemi , Shahram Habibzadeh , Pariya Bakhshpoori,
Volume 9, Issue 4 (12-2009)
Abstract

  Background & Objectives: Pneumonia is one of the most fatal infectious syndromes with various etiologies. Mycoplasmas require special therapeutic approach as they are not sensitive to betalactams such as penicillin.

  Regarding lack of comprehensive studies relating to mycoplasmas' part in pneumonia in Iran, the current study was conducted.

  Methods: This is a descriptive study performed on 80 patients diagnosed with community acquired pneumonia and hospitalized in infectious diseases ward of Immam Khomeini Hospital (Ardebil, Iran) in over a one year time span.

  Blood samples for titration of anti-mycoplasmal IgGs and IgMs were taken from all patients.

  Results: Out of 80 hospitalized patients 40 were men and 40 were women. Mean age of the studied group was 59.91 years and 76.6% of patients lived in urban areas. We observed positive IgM in 5 patients (6.3%) and positive IgM in 20 patients (25%). Etiologic cause of 6 % of hospitalized patiants with community acquired pneumonia was mycoplasmal. We could not specify any particular clinical finding assisting to differentiate mycoplasmal pneumonias from other types of pneumonia. All the patients with positive IgM titrations had positive agglutination titers of 1/16 or 1/32, therefor under any circustances that performing of IgM titration is not possible, agglutination test can be used as an alternative.

  Conclusion: Approximately 6.7 % of community acquired pneumonias in adults' infectious diseases ward of Imam Khomeini Hospital, were etiologically related to mycoplasmas. Therefore, regarding limitations for PCR analysis and antibody titration, administration of antibiotics with antimycoplasmal properties is necessary.


Masoomeh Parvizi, Seyed Fazlollah Mousavi, Khadijeh Mohammadi , Mohsen Arzanlou,
Volume 16, Issue 3 (10-2016)
Abstract

Background & objectives: Streptococcus pneumoniae is  one of the major causes of vaccine - preventable diseases worldwide. Current pneumococcal vaccines consist of serotype specific capsular polysaccharide antigen and do not offer full clinical protection against pneumococcal diseases. Due to such limitations, a new generation of protein-based pneumococcal vaccines is being developed. The objective of this study was to determine the distribution of gens encoding five protein antigens including pneumococcal histidine triad D and E (phtD, phtE), rlr- regulated gene A (rrgA), Autolysin (lytA) and Pneumococcal surface protein C (pcpC) among pneumococcal isolates collected from nasopharyngeal specimens in healthy children.

Methods: A total of 43 pneumococcal isolates were collected from nasopharyngeal specimens of healthy children attending the kindergartens in Ardabil province. The strains were identified using optochin susceptibility and bile solubility testes and further confirmed by amplification of capsular polysaccharide A gene (cpsA). PCR was used for screening the presence of pcpC, phtD, phtE, rrgA and lytA genes.

Results: 81.4 % of isolates were found to contain at least one of the tested genes. lytA, pcpC, phtE, phtD and rrgA were detected in 70, 60, 39.5, 35 and 25.5 percent of isolates, respectively. The results showed that the genes were not distributed consistently among the isolates and for obtaining a full coverage pneumococcal vaccine, multiple choices of these antigens should be included.


Hoosna Sarvazad, Mojtaba Darbouy,
Volume 17, Issue 3 (10-2017)
Abstract

Background & objectives: One of the main problems in the control of nosocomial infections due to Klebsiella pneumoniae is increase of antimicrobial resistance and prevalence of extended spectrum β-lactamase (ESBLs) producing isolates. The aim of this study was to investigate the correlation of antibiotics resistance with SHV, CTX-M and TEM extended-spectrum beta lactamases genes among Klebsiella pneumoniae isolates isolated from the patients in Kermanshah hospital.
Methods: The clinical isolates of Klebsiella pneumoniae were collected during the spring from Kermanshah hospitals, and identification of Klebsiella pneumoniae strains was performed using standard microbiological and biochemical tests. Antibiotic resistance of Klebsiella pneumoniae isolates was determined using disk diffusion method. Then, the presence of CTX-M, SHV, and TEM was investigated using multiplex-PCR method. Finally, the relationship between variables was analyzed by SPSS-22 software using logistic regression and chi-square.
Results: A total of 98 isolates out of 112 samples were identified as Klebsiella pneumonia. Also, 82.8% of isolates were resistant to cefotaxime, 40.2% to ceftriaxone, 62.88% to ceftazidime, 3.9% to imipenem, 39.17% to cefepime, 64.94% to cefixime and 26.8% to amikacin. Further, 35.55% of isolates had CTX-M gene, 63.91% of isolates had SHV gene and 9.27% of samples had TEM gene.
Conclusion: The presence of CTX-M, SHV and TEM genes along with high antibiotic resistance are very concerning, indicating the importance of rational use of antibiotic for the treatment of infectious diseases.
 
Lida Jalali Dizage, Mohammad Reza Nahaei, Javid Sadegi,
Volume 19, Issue 3 (10-2019)
Abstract

Background & objectives: Urinary tract infection (UTI) is one of the most common types of hu­man infections and Escherichia coli and Klebsiella pneumonia are the main causes of urinary tract infection among the gram negative bacteria. The prevalence of extended-spectrum β-lactamases (ESBLs) among these bacteria and hence resistant strains to β-lactam antibiotics have increased in recent decades. Several types of extended-spectrum β-lactamases, such as TEM, SHV and CTX-M have been identified, which are prominently present in the strains of E. coli and K. pneumoniae. The objective of this study was to determine the prevalence of TEM and SHV genes in E. coli and K. pneumoniae isolates of urinary tract infections by using phenotypic and molecular (PCR) tech­niques in microbiology laboratory at medical school of Tabriz Islamic Azad University.
Methods: In this cross-sectional descriptive study, 50 isolates of E. coli and 50 isolates of K. pneumoniae collected from uri­nary tract infections from out-patients in Tabriz. Antibiotic sensitivity patterns of isolates were stu­died against 14 antibiotics by disk diffusion test (Kirby Bauer) and also confirmatory tests were performed using combined antibiotic tests. Finally TEM and SHV genes were investigated using molecular methods (PCR).
Results: Twenty five isolates (25%) out of 100 bacterial isolates were identified as ESBL-producing isolates of which 13 isolates (26%) were E. coli and 12 isolates (24%) were K. pneumoniae. The TEM and SHV genes were detected in 2% and 4% of E.coli and 0% and 2% of K. pneumoniae isolates, respectively.
Conclusion: The presence of these genes among our isolates confirmed ESBL genes in these medically important bacteria leading to resistance against β-lac­tam antibiotics which are routinely used in their treatments. The low frequency of the studied genes could be because of the source of our isolates from out-patients which are not generally exposed to antibiotics
Narges Chitsaz, Ahmad Reza Meamar, Elham Razmjou, Soheila Shafaghi-Sisi, Maryam Alipour, Maryam Sadeghi, Zahra Rampisheh, Zeinab Ghasemi, Rasoul Aliannejad, Alireza Badirzadeh,
Volume 23, Issue 4 (1-2024)
Abstract

Background: Pneumocystis jirovecii (P. jirovecii) causes Pneumocystis pneumonia (PCP) in people, especially the immunocompromised ones. It is also one of the serious causes of numerous lung problems in affected patients. Since documented data about P. jirovecii is not available in patients with pulmonary infections in Tehran, this study aimed to investigate the molecular epidemiology and parasitology of Pneumocystis to determine the frequency of the organism infection.
Methods: Bronchoalveolar lavage (BAL) samples were collected for 367 patients hospitalized in the lung department of Shariati Hospital in Tehran from July 2022 to July 2023. The samples were analyzed using Giemsa staining and molecular methods. After DNA extraction from samples, Nested polymerase chain reaction (Nested PCR) was employed for the amplification of the 18SrRNA gene and identification of P. jirovecii. The PCR products of Nested PCR were sequenced for final confirmation. 
Results: Out of 367 samples, only one sample (0.27%) and 28 samples (6.7%) were found to be positive through parasitology and NestedPCR analysis, respectively. P. jirovecii was detected in seven (25%) and 21 (75%) immunocompromised and immunocompetent patients, respectively. Fever, shortness of breath and dry cough were the most common clinical symptoms among patients with Pneumocystosis. Patients with pulmonary disorders are prone to colonization by pneumocystis, which increases the risk of pneumocystosis and makes them a reservoir for transmission to susceptible people.
Conclusion: It can be concluded that patients with distinct lung disease are prone to colonization by Pneumocystis and, importantly, are at risk of infection. Also, according to the current study, Nested PCR was a suitable method for detecting P. jirovecii organisms because it had a very high sensitivity and specificity.
 

Page 1 from 1     

مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
Persian site map - English site map - Created in 0.23 seconds with 36 queries by YEKTAWEB 4623