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Showing 15 results for Lif

Aghil Habibi, Soghra Neekpoor, Mahnaz Seyedolshohda, Hamid Haghani,
Volume 8, Issue 1 (4-2008)
Abstract

Background & Objective: As life expectancy increases health promotion behaviours are even more important, particularly with regard to maintaining functional independence and improving quality of life (QoL). The purpose of this study was to explore the relationship
between health promotion behaviours and quality of life among elderly people in west region of Tehran.
Methods: This was a descriptive-correlational study. Through multi-stage sampling method, 410 participants over 60 years old and cognitively intact were selected to contribute in the study. The data-gathering tool consisted of a 2-part questionnaire Health Promotion Behaviour Checklist and Short Form Health Survey (SF12) that were used to measure QoL.
Results: The results of the study showed that there were statistically significant differences in QoL of the elderly related to 'exercise or walking and consumption of milk, dairy products, meat, vegetables and fruits and 'low salt diet', 'low fat diet', 'health check up', 'blood pressure (BP) (p< 0.05). The Elderly with high quality of life had more exercise or walking and consumption of milk, dairy products, meat, and fresh fruit and vegetables and the elderly with low quality of life, had better observed low salt diet, low fat diet, health condition control and blood pressure control.
Conclusion: Regarding the results we found that health promotion behaviours and the quality of life are related meaningfully, so, considering old people as a vulnerable group by health authorities, it is recommended to provide this group with programs and facilities to promote their health behaviours, social participation and to improve health care and provide consultation services.
Saeid Sadeghie Ahari , Solmaz Arshi , Manoochehr Iranparvar , Firouz Amani, Hosein Siahpoosh,
Volume 8, Issue 4 (12-2008)
Abstract

 Background & Objectives: The prevalence of diabetes and its different methods of treatment have significantly been increased in the last two decades. The actual effect of these treatments is a common topic in the patients’ health and quality of life among these patients has a considerable importance in the community medicine. This study was designed to indicate the quality of life in the diabetic type II patients.

  Methods: This was a cross-sectional, descriptive analytic study in 2004 on 110 type 2 diabetic patients who had referred to Bu Ali Hospital in Ardabil. The patients were randomly selected and took the SF-36 Questionnaire and in the end the data were analyzed by SPSS.

  Results: The average age of the patients was 52.5 with the standard deviation of 11.3 years. 73 of the patients were female (66.4%) and rest of them were male. The average period of sickness among diabetics was 8 years from the time of diagnosis with a standard deviation of 6.2 years. The average of duration of therapy was 7.7 years with 6.1 years standard deviation. 51 patients (46.36%) had the history of hospitalization. Vitality indicator was low in 39.1% of patients. Social functioning was low in 50% of patients. In general, by adding up the quality of life’s various indexes scores based on SF-36 questionnaires standard coefficients, 77% of patients had intermediate and low quality of life.

  Conclusion: According to this study most of the patients in this study had a low quality of life.


Maryam Namadi , Asiyeh Movahdpoor,
Volume 9, Issue 2 (6-2009)
Abstract

  Background and objectives: Quality of life is an important aspect in the evaluation of different therapeutic interventions. Quality of life assessment helps to find patients problem and revise their therapeutic method. The purpose of this study was to evaluate the life quality among patients receiving renal transplantation in comparison with hemodialysis in Ardabil university of Medical Sciences.

  Method: In this comparative study a total of 70 patients with renal transplantation and 93 hemodialytic patients were chosen through census sampling. An interview based questionnaire was administered for subjects to gather information on demographic characteristics and kidney disease quality of life scale.

  Results: Findings show that, 65.7 percent of transplanted patients reported their quality of life as good. While, in 65.6 percent of hemodialytic patients life quality was moderate. The average quality of life score in transplanted patients was 95.44 ± 12.44 SD while it was 83.53 ± 14.89 for the patients under dialyzes. The difference between the two groups were significant (p< 0/001).

Conclusion: It is concluded that by transplantation, the life quality of in CRF patients may be improved.
Mahin Kamali Fard, Raziyeh Alizadeh , Fahimeh Sehati Shafaei , Mortaza Gojazadeh,
Volume 10, Issue 1 (4-2010)
Abstract

  Background & Objectives :Prematurity is still one of the main causes of neonatal mortality and morbidity that makes a lot of financial, psychosocial and emotional problems.

  Although the main cause of preterm labor is unknown but understanding of its risk factors is important for planning health policies for preventing and decreasing the rate of preterm labor. This study aimed to compare lifestyle of women with term and preterm delivery.

  Methods :This research is a case-control study. Subjects of this study were 132 women with preterm labor and 264 women with term labor that referred to Educational and Medical Center of Alzzahra. The subjects were selected by convenience method and matched in age and educational level. Data were collected by questionnaire containing two sections, demographic characteristics and woman's lifestyle including,nutrition, exercise, smoking and use of alcohol and substance abuse, social support, stress management and self care. Data were analyzed by SPSS with descriptive statistics and statistical tests of t Test, Man Witny U, χ 2 and Fisher's Exact Test.

  Results : The results of this study showed significant differences in nutrition, smoking, use of alcohol, substance abuse, social support, stress management and self care between two groups, but the mean score of exercise in term and preterm birth was not statistically significant.

  Conclusion: The findings of our study suggest that there is a relation between lifestyle in pregnancy and preterm birth. Lifestyle is changeable and achieving this aim is possible by efforts to increase health education .


Shaban Alizadeh , Shahab Bohlooli , Ali Abedi , Seiyed Hadi Mousavi , Behzad Jafazadeh, Norooz Hamrang , Ali Imani,
Volume 10, Issue 4 (12-2010)
Abstract

  Background & Objectives: Leptin is a hormone secreted from adipocyte tissue with established role in the differentiation and proliferation of hematopoietic cells. This hormone has major impact on fat metabolism. LIF is a pleiotropic cytokine with extensive hematopoietic, neuronal, and endocrine actions. LIF and IL-6 are leading to decreased level of leptin by activating signaling via their own receptors. Body mass index (BMI) has a direct connection with the leptin. It seems that Hb and HCT levels are also implicated in disease prognosis. This study was conducted to evaluate leptin, LIF and IL-6 serum levels and also to measure the amounts of BMI, Hb and HCT in lymphoid leukemia patients .

  Methods: The study was carried out on 30 leukemia patients (15 cases ALL and 15 cases CLL). Fifteen healthy subjects were considered as control. Serum levels of leptin, LIF and IL-6 were measured by ELISA. BMI was calculated by statistical formula. The amount of Hb and HCT were measured by cell counter. Data was analyzed by SPSS software. Statistical differences between groups were assessed by t test, and p<0.05 was considered significant.

  Results: Leptin serum level showed a decrease in ALL patients (p<0.002), but there was an increase in CLL patients when comparing with control group (p<0.003). BMI and serum levels of leptin, LIF and IL-6 were showed a significant decrease in ALL patients in comparison with control group (p<0.05). Although, LIF serum levels and BMI in CLL patients showed a decrease, a significant increase in leptin serum level was observed (p<0.05). A decrease in IL-6 level was also observed which was not significant. The relation between BMI and leptin serum level in ALL and CLL patients were not significant, nevertheless it was significant in control group (p<0.05). Hb and HCT levels in both ALL and CLL patients showed a significant decrease (p <0.05).

  Conclusion: Findings on serum levels of LIF, IL-6, Leptin, Hb and HCT and also its relations with BMI in ALL and CLL patients suggest that, these factors may have important role in physiopathology of lymphoid leukemia.


Arezo Samadi Bilehsavar , Shabnam Nohesara, Mohammadreza Najarzadegan, Parviz Molaei , Kaveh Alavi, Amirhossein Nadoushan ,
Volume 17, Issue 1 (4-2017)
Abstract

Background & aims: The main purpose of this study was to investigate the impact of NEO personality dimensions on general health, quality of life and job burnout in a sample of faculty members of Iran University of Medical Sciences.

Methods: In this correlational study, data were collected by convenience sampling using General Health Questionnaire (GHQ), WHO Quality of Life- Brief (WHOQOL-FFI), Maslach Burnout Inventory (MBI) and NEO-FFI. In order to analyze the data, statistical indices, including mean, standard deviation and Pearson correlation coefficient were used. 

Results: The results showed a significant correlation between  personality dimensions, including  neuroticism, extraversion, conscientiousness and agreement with any public health variables (correlation coefficients 0.435, 0.533, 334.513, 0.0) and quality of life (correlation coefficients 0.294, 0.438, 312.459, 0.0) and burnout (correlation coefficients 0.259, 0.351,       -0.302, -0.299, 0.0) , respectively in the Department of Surgery, but openness to experience had  no significant correlation with any of the above-mentioned variables. Also, there was a significant relationship between the three variables of public health, quality of life with burnout.

Conclusions: According to the findings, it can be concluded that in the participants of this study, increase of neuroticism scores was associated with decreased general health and quality of life scores and increased job burnout. Further, increased extroversion scores were associated with increase in general health and quality of life and decrease in job burnout scores.


Sara Taghizadeh , Alireza Moradian, Mohammad Narimani ,
Volume 19, Issue 1 (4-2019)
Abstract

 
Background & objectives: Chronic illnesses are one of the most important causes of mortality. The purpose of this study was to investigate the relationship between perfectionism and stress with life satisfaction in cardiovascular patients.
Methods: The research method is descriptive correlational. The statistical population of this study included patients who came to receive the services in Ardabil in the first half of 1396. The sample consisted of 60 cardiovascular patients who were selected by simple random sampling. Data was collected using questionnaires of perfectionism scale, stress scale and life satisfaction scale. Data were analyzed by descriptive statistics and multiple regression analysis using spss-19 software.
Results: The results showed that there is a significant negative relationship between perfectionism and life satisfaction. Also, there was a significant negative relationship between stress and life Satisfaction (p<0.01). In other words, with increasing stress, life satisfaction decreases. There is a multiplicity relationship between perfectionism and stress with life satisfaction (p<0.01).
Conclusion: The results of this study showed that reducing the perfectionism and stress of individuals helps to increase the satisfaction of people from life and also effective in the process of treatment.
 
Hasan Ghobadi, Somaieh Matin, Ali Nemati, Hasan Javadi , Reza Alipanah-Moghadam , Mehdi Saeidi-Nir ,
Volume 19, Issue 1 (4-2019)
Abstract

 
Background & objectives: Chronic Obstructive Pulmonary Disease (COPD) is accompanied by systemic inflammations and is characterized by irreversible airflow limitations. Leptin is a cytokine with pre-inflammatory effect. However, there have been no studies on the effect of conjugated linoleic acid (CLA) on the serum leptin concentration in COPD patients. Therefore, the present study aimed to explore the effect of CLA on the serum leptin level, lung function and quality of life in COPD patients.
Methods: This interventional study was conducted on 90 COPD patients. The patients were randomly divided into two groups (supplement and placebo) with 45 patients per group. After obtaining written consent from the patients and recording their demographic characteristics, the spirometry was performed and COPD assessment test (CAT) score was calculated. Moreover, a fasting blood sample was collected from each of them in order to analyze their serum leptin concentration. After that, the patients in the supplement group were administered with 3.2 g/day of CLA for 6 weeks. The patients in another group received placebo. After the intervention, spirometry, CAT score calculation and blood sampling were repeated for all of the patients and the obtained results were analyzed.
Results: after the intervention, a significant decrease both in the serum leptin level and in CAT score as a quality life marker  was observed in the supplement group (p<0.05). Moreover, the FEV1 levels as a lung function test, increased significantly in the supplement group after the intervention (p<0.05). Although, the difference between the two groups was not significant.
Conclusion: The use of CLA supplement can improve COPD patients’ quality of life through decreasing the serum level of leptin in their blood.
 
Afsaneh Mafi, Abbas Moghadam, Nilofar Moghadam,
Volume 19, Issue 4 (1-2019)
Abstract

 
Background & objectives: Nephrotoxicity is the most important side effect of gentamicin and is a concern in clinical situations. There are no therapeutic tools to prevent or palliate nephrotoxicity. Platelet-rich plasma (PRP) as a source of growth factors can be considered as a therapeutic tool. Therefore, the aim of this study was to investigate the effects of PRP on proliferation of epithelial cells of convoluted tubules in gentamicin-treated rat model by stereological method.
Methods: 28 male rats (200-300g) were divided into four groups, each group containing 7 animals: control, patient without treatment, sham and experimental groups. Gentamicin was injected intraperitoneally (80mg/kg/daily) for 8 days. 24 hours after the last injection, blood samples were collected to assess the serum levels of blood urea nitrogen and creatinine. The sham and experimental animals were subjected to intrarenal injection of 100 µl normal saline and PRP, respectively. 3 days later, the rats scarified under the deep anaesthesia and their kidneys were removed, prepared histologically and stained. The stereological methods were used for estimating the number of epithelial cells in convoluted tubules. Data analysis was done using SPSS 26. Differences between groups were compared with one-way analysis of variance and Duncan’s multiple range test. p<0.05 was considered as significant.
Results: PRP increased the number of epithelial cells in the convoluted tubules in gentamicin-treated animals (p<0.05).
Conclusion: It seems that PRP can induce proliferation of epithelial cells of convoluted tubules in gentamicin-treated rat model.
Bahman Ebrahimi-Torkamani , Marefat Siahkouhian, Ali Khazani, Anoshirvani Sajad, Bolboli Lotfali, Maryam Asadi,
Volume 20, Issue 3 (10-2020)
Abstract

Background & objectives: Over the last couple of decades, research has focused on attempting to understand the genetic influence on sports performance. Whole exome sequencing (WES) has great potential to explore all possible genetic variants associated with physical performance. However, this new technique has not been used in sports genetics research. Therefore the aim of this case study was to report new variants in genes involved in skeletal muscles strength (ACE, NOS3, IGF1R, IL-6) in an elite weightlifter using WES.
Methods: After obtaining a written testimony from a 32-year-old man, who is a member of the Iranian national weightlifting team, 5 cc of blood was taken and then DNA was extracted. DNA samples were analyzed using the whole exome sequencing method.
Results: Whole exome sequencing analysis revealed a missense variant (99454613G>A) in IGF1R, 22771156C>T polymorphism in IL-6, 150695726T>C and 150704250C>G polymorphisms in NOS3 and 61573761T>C and 61564052A>G in ACE genes.
Conclusion: Results of whole exome sequencing analysis revealed a missense variant and polymorphism in muscle strength and hypertrophy related genes in this elite weightlifter. However, other studies with larger sample sizes are needed to investigate the relationship between these variants and power athlete status. 
Ayda Naderi Pour, Soheila Derisavy Jorfian,
Volume 22, Issue 1 (4-2022)
Abstract

Background & objectives: The 2019 coronavirus pandemic is a major threat to global public health due to unprecedented individual and social fear and anxiety and it puts significant stress on health-related quality of life and challenges health care professionals, including dentists, with increasing patient burdens, unprecedented disruptions in normal life and The high risk of being exposed to the disease has put them in stressful situations and therefore they are more exposed to stressful situations that can affect their quality of life. Therefore, this study was conducted with the aim of investigating the level of perceived stress and the quality of life of the students and professors of Ardabil Dental School in the face of the outbreak of the 2019 coronavirus disease in 2021 and the relationship between these two variables with the demographic characteristics of the participants.
Methods: To measure the level of perceived stress, Cohen's Perceived Stress Questionnaire was used, and to measure the quality of life, the World Health Organization Quality of Life Standard Questionnaire-Abbreviated (WHOQOL-BREF) was used. The statistical population in this study is all dental professors and dental students of the Faculty of Dentistry of Ardabil University of Medical Sciences. A significance level of less than 0.05 was considered.
Results: From the statistical population of this study, a total of 227 people including 33 professors and 194 students participated in the study. There was no significant relationship between demographic variables and perceived stress variables and quality of life. Perceived stress and quality of life were higher for professors than for students during the pandemic. There was a direct relationship between perceived stress variables and quality of life in both groups. The level of perceived stress in both groups was lower than the optimal level and the quality of life in both groups was higher than the optimal level.

Conclusion: Students and professors of Ardabil Faculty of Dentistry experienced moderate stress during the Covid-19 epidemic and had a good quality of life. By comparing between the two groups of participants, professors had more perceived stress.
Nahid Ahmadian Yazdi, Aziz Kamran, Somayeh Matin, Afshan Sharghi,
Volume 22, Issue 4 (1-2023)
Abstract

Background & objectives: Even though clinical empathy is one of the clinical competencies of medical students and there is a high emphasis on teaching and learning, it decreases during medical education. This study investigated the relationship between burnout, quality of life and clinical empathy in medical students.
Methods: this exploratory cross-sectional study used the Jefferson empathy questionnaire, WHO quality of life questionnaire and burnout inventory. All three questionnaires are standard, and their validity and reliability have been confirmed in various studies in Iran. The research population was the Ardabil University of Medical Sciences internship medical students, for which the census sampling method was used. Various statistical tests, such as Pearson and spearman correlation, Chi-square, etc., were used for data analysis.
Results: Out of 130 students, 128 (98.4%) completed all of the questionnaires. Data analysis showed that 98% of students suffered from moderate burnout and 2% of them had severe burnout. About 44% of students were satisfied or very satisfied with their health status and 33% of students were dissatisfied or very dissatisfied. The mean score of clinical empathy in students was 79.46±9.82. Data analysis showed a statistically significant inverse relationship between quality of life and burnout (p=0.0001).
Conclusions: Considering that the situation of students was not very favorable in terms of all three variables, non-curricular programs seem to be essential for improving student adaptation mechanisms to the job-related situations in medical students and promoting clinical empathy.
 
Yalda Mahfouzi, Manijeh Firoozi, Sima Khavandizadeh Aghdam ,
Volume 23, Issue 1 (4-2023)
Abstract

Background & objective: The purpose of this research was to evaluate the effectiveness of self-compassion training on the resilience and quality of life of mothers with mentally retarded children.
Methods: The current research was practical in terms of purpose. The research method was experimental with a pre-test-post-test design in two groups. The statistical population of the research was mothers with mentally retarded children in Ardabil city in 1401 and also, the availability sampling method was used. Among the qualified volunteers, 100 people entered the study and were randomly replaced in two groups of 50 people (self-compassion training and control). The self-compassion training group received eight 90-minute sessions. Standard questionnaires on resilience and quality of life were used to collect information. The data collected in the pre-test and post-test stages were analyzed by multivariate analysis of covariance using SPSS version 26 statistical software.
Results: The findings of the present study showed, there is a significant difference between the control and experiment (p<0.01) groups in the post-test scores in terms of perception of individual competence (F=441.15), trust in individual instincts and tolerance of negative emotions (F=423.05), positive acceptance of change and secure relationships (F=399.82), control (F=261.60) and spiritual effects (F=241.62) variables. Also, in respect of individual physical health (F=66.60), mental health (F=157.29), social relations (F=146.62) and environmental health (F=135.45) variables in the post-test scores, there is a significant difference between control and experiment (p<0.01) groups.
Conclusion: Therefore, it can be concluded that self-compassion training has a positive effect on the dimensions of the resilience of mothers with mentally retarded children and improves individual competence, trust in individual instincts and tolerance of negative emotions, positive acceptance of change and safe relationships, control and spiritual effects. Also, self-compassion training has a positive effect on the dimensions of the quality of life of mothers with mentally retarded children and improves individual physical health, mental health, social relationships and environmental health.
 
Mehta Mir Hashemi, Abbas Tafakheri, Fatemeh Hajibabaee, Hadis Ashrafizadeh, Amir Ahmad Shojaei,
Volume 23, Issue 2 (7-2023)
Abstract

Background & Objective: Futile or fruitless life-saving interventions are in conflict with the four principles of medical ethics, which are not only ineffective for the patients, but also have a high burden on society. Therefore, this study aimed to determine the causes of unsuccessful life-saving treatment and interventions from the point of view of care providers in the neurology and neurosurgery departments of Tehran University of Medical Sciences hospitals.
Methods: The present study is a descriptive cross-sectional study that was conducted on 64 doctors and 72 nurses working in hospitals affiliated to the Tehran University of Medical Sciences in 2018. A 25-item researcher-made questionnaire was used to collect data. Spss-24 software and descriptive statistics tests were used to analyze data.
Results: The average age of doctors and nurses was 34.25±5.1 and 35.12±8.2 years, respectively. From the point of view of physicians and nurses, the most important reason for the ineffective provision of life-saving services was the lack of legal, moral and Islamic permission and guidelines to cut off life support devices and the lack of resuscitation in patients facing death (end stages of life).
Conclusion: The results of this study showed that, from the point of view of nurses, the most common reasons for providing futile care and cure are the moral and humane obligation of the treatment and care team to provide ineffective life-saving interventions, and from the point of view of the physician, the lack of legal, ethical and religious permission and instructions to cut off life support devices in patients has resulted in death. Some of the causes of unnecessary care were presented in this study, and some of these causes cannot be solved without solving theoretical problems and practical expert studies. Developing guidelines to define futile treatment, especially in end-of-life care, and providing solutions to control and manage treatment and unsuccessful life-saving interventions seems necessary.
                                      
 
Reza Namadkolahi, Avissasadat Meraji, Safa Yaltaghiani, Somayeh Hekmatfar,
Volume 24, Issue 1 (4-2024)
Abstract

Background: Early childhood caries is a disease that affects the quality of life of a child and his overall health; it can interfere with the child's daily activities and growth process. This disease is affected by various factors such as diet, oral hygiene, social health factors and psychological issues. This study aimed to investigate the relationship between early childhood caries in children and the parents’ quality of life.
Methods: This cross-sectional descriptive study was conducted on 552 children aged 12 to 71 months in Ardabil city. The convenient sampling method was used and participants were patients who referred to Ardabil Dental Health Center. Dmft index (decayed, missing, and filled teeth) was assessed after examining the children. The World Health Organization questionnaire was used to evaluate the quality of life of the parents. The demographic information of children and parents was also determined. Statistical analysis included, kruskal-wallis, t-test and linear regression.
Results: The average score of the quality-of-life questionnaire was 66.42±17.91. No significant correlation was found between the mean quality of life of parents and dmft index. (p=0.916, r=0.008) A significant difference was observed between the child's dental caries and the father's age and education. (p<0.05) There was no significant difference in the mean dmft index, 5.32±0.5 in boys and 5.85±4.7 in girls. (p=0.459)
Conclusion: This study showed that the general quality of life of parents and its sub-branches such as the place where the child lives, the social and physical health of the parents are not directly related to early dental caries in children.     

 

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