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Showing 2 results for L-Carnitine
Iraj Faizi, Saeid Smaeilpour, Ali Nemati , Khatere Isazadeh, Farideh Faizi, Vahid Montazeri,
Volume 17, Issue 3 (10-2017)
Abstract
Background & objectives: The use of supplements such as L-carnitine, optimum nutritional support and early feeding after surgery in cancer patients can be important in the prevention of cancer complications. The aim of this study was to determine the effects of early L-carnitine-rich feeding on complications of esophageal cancer surgery and duration of hospitalization.
Methods: In a clinical trial, 50 patients with esophageal cancer under surgery in two equal groups were randomly selected. Nutritional information was obtained using food record questionnaire. Basic blood samples and 24-hour urine samples were taken in order to measure the hematological parameters (like blood cell count, hemoglobin, hematocrit and blood urea) and nitrogen balance, respectively from two groups at the beginning and end of the study. Then, the intervention group received 3 g L-carnitine daily in 3 doses on the first day after the complementary operation, with a routine hospital diet at each meal, and the control group received a routine hospital diet for ten days. Data were analyzed using independent t-test, paired t-test and chi-square test.
Results: The results showed that changes in the mean BUN and nitrogen balance were significantly different after intervention between the study groups (p<0.05). Patients with early L-carnitine-rich feeding had less hospitalization time in hospital wards and were discharged earlier (p<0.05).
Conclusion: The results of this study showed that early L-carnitine-rich feeding after surgery has probably a positive effect on the duration of hospital stay in patients with esophageal cancer.
Soheila Fakhrian Roghani, Allahyar Arabmomeni,
Volume 23, Issue 4 (1-2024)
Abstract
Background: Obesity is a major health problem worldwide. Therefore, the purpose of this study was to determine the effects of l-carnitine supplementation on physical factors related to health and lipid profiles in obese female children with basic gymnastics exercises.
Methods: In this quasi-experimental study, with a pre-test-post-test design and a placebo group, 60 obese children among the girl students of Isfahan with BMI=30.28 kg/m2 were selected purposefully and were divided into 4 groups (Basic gymnastics training, L-carnitine consumption, Combined, and Placebo). The training protocol was implemented for 12 weeks, three times a week, and 45 minutes for each session. Furthermore, the groups of L-carnitine consumption and combined used L-carnitine tablets with a dose of 2 g per day for 12 weeks. To analyze the data, multivariate covariance, and post hoc Tukey tests were used.
Results: A significant increase in Cardio-respiratory endurance, muscular endurance, muscular strength and flexibility was observed in both basic gymnastics training and combined groups (p≤0.001). In addition, a significant decrease in total cholesterol, triglyceride, and LDL and a significant increase in HDL were observed in the basic gymnastics training, and combined groups (p≤0.002). Also, the changes caused by the combined group on all variables were significantly better than other groups.
Conclusions: These findings indicate the beneficial effects of basic gymnastics training along with L-carnitine supplementation on physical factors related to health and lipid profile in obese children. Therefore, the combined use of basic gymnastic exercises and L-carnitine supplementation can be useful to improve these variables.
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