Hydatic cyst is caused by Echinococus worm, that involves any part of the body, sometimes it is presented in organs such as thyroid, breast and other organs. Axillary that may be consider adenopathy or metastasis and do biopsy, which so there is danger of leakage, anaphylaxis or relaps.

 The reported case was 39 years old female presented with painless axillary mass without inflammation since 19 years ago that slowly enlarged. Physical findings suggested hydatid cyst which was confirmed with ultrasonography and IHA for Echinococus granolosus and other diseases ruled out. She was operated and she had no relapses after 1.5 years follow up.

 Background and objective: Cystic Echinococcosis (CE) is a cosmopolitan and prevalent zoonosis in the world. It caused by larva of Echinococcus genus�species. CE is medically and economically one of the important parasitic zoonoses in Iran especially Moghan Plain. So far no survey was conducted to determine the rate of CE in this region.

 Method: The subjects of this descriptive- analytic study were people of the Moghan plain. The prevalence of the disease was determined with serologic examination using ELISA test. ELISA was carried out using HCF-Ag that obtained from a diseased sheep. Household information was recorded in questionnaires before collecting serum samples. The results were analyzed by SPSS using statistical tests.

 Result: Out of 2008 samples, 1267 were female and 734 were male. At all 9.2 % (184) of sera were found to be positive.

 Conclusion: This survey determined more prevalence of Cystic Echinococcosis in women (%10) than men (%7.9) and infection is more in places that keep much Dogs.

  Hydatid disease infection in humans is caused by larva of Echinococcus granulosus. Definitive hosts are carnivores such as dogs, while intermediate hosts are herbivores. Humans can also be intermediate hosts. Hydatid disease is clinically related to the presence of cysts, most frequently in the liver and the lungs and less frequently in the other organs such as kidney, spleen, brain, heart and bone. In this article, a case of splenic hydatid cyst is reported. A 50-years-old man was admitted to the clinic with a abdominal pain lasting for two weeks. Sonography and computed tomography (CT) scan revealed a splenic cyst. Cyst was removed by a surgery. The diagnosis of a hydatid cyst was confirmed by histopathology.

  Background & objectives: Hydaticosis is a zoonotic helminthic disease of human and other intermediated hosts in which larval stages of the tapeworm Echinococcus granulosu transfect human. The liver and lung are the host tissues for the hydatid cyst . It is unknown which mechanisms are involved in infertility of the cyst and suppression of the fertile cyst. This study was aimed to evaluate the expression of the apoptosis inducing-ligands such as TRAIL and Fas-L in germinal layer of the cyst and human normal tissue surrounding the cyst that is one of the unknown host innate immunity mechanisms against the hydatid cyst.

  Methods: In this study, four isolated hydatid cysts were used which had been diagnosed in patients by radiography and parasitological examination in Mashhad Ghaem hospital. Furthermore, the germinal layer of the cyst and accompanied normal peripheral tissues were separated by scalpel in sterile conditions. After homogenization, expression of TRAIL and Fas-L genes were studied by semi-quantitive RT-PCR method.

  Results: The TRAIL and Fas-L showed significant higher level expression in germinal layer of infertile cyst than the fertile cyst and host normal tissues.

  Conclusion: The host tissue-induced apoptosis of germinal layer of the fertile cysts is probably one of the infertility mechanism in patients with hydaticosis

  Background &objectives: Echinococcosis, referred to as hydatid disease or hydatidosis, is a parasitic disease caused by larval stage of Echinococcus granulosus. In the life cycle of this parasite, dogs and other carnivores are definitive hosts and herbivores are intermediate hosts. Humansin this cycle may incidentally involve by ingestion of parasite eggs and play as intermediate host. Hydatid disease can involve any organ but liver and lung are the most commonly affected organs and kidney, brain, heart, bone may also be affected to a lesser degrees. Cerebral hydatid cyst occurs in about 2% of all echinococcosis cases. In this paper we report two cases of cerebral echinococcosis in whom diagnoses were made based on MRI findings and confirmed by pathology reports after surgery.

  First Case Report: The first case was a 30 years old man who was admitted after an episode of generalized tonic-clonicseizure. The MRI imaging performedand patient underwent surgery with diagnosis of a right frontal cystic lesion. The patient was improved progressively and there was no seizure attack and recurrence during 18 months follow up period.

  Second Case Report: The second case was a 28 years old woman presented by headache and abnormal behavior. MRI of this patient revealed a large cystic lesion in left frontal lobe and then underwent surgery. No complication was seen during postoperative period. The headache and behavioral disorder were improved completely and there was no sign of recurrence during 18 months follow up period.

  Conclusion: Hydatid cyst should be considered as a differential diagnosis of cystic brain lesions in endemic areas. Although hydatid cyst is a benign lesion but surgical removal of it without rupture is very important for prevention of probable future complications.