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Showing 3 results for Hepatitis B
Kazem Sakha, Arman Malekian,
Volume 5, Issue 2 (6-2005)
Abstract
Background & Objectives: Regarding the admitted cases at early infancy in Tabriz Pediatrics Medical Center, this research was carried out to determine the role of Hep.B. vaccination in the incidence of ITP. Methods: We studied all patients’ admission files in Tabriz Pediatrics Center from 1993 to 2002. The patients were under 6 months of age and hospitalized with the impression of ITP. There were 25 infants whose ITP was diagnosed upon their clinical findings, blood counts and bone marrow aspiration and confirmed by exclusion of other causes of thrombocytopenia. Hep. B. vaccination has been included in routine immunization in Iran since 1993. In order to compare the incidence rate of ITP before and after 1993, we also sought all ITP patients’ files at the same age group who had been admitted to Tabriz Pediatrics Center during the decade before the beginning of routine Hep.B. vaccination (i.e. 1982 to 1992). Results: This study shows a considerable increase in incidence of ITP in infants under 6 months of age between 1993 asnd 2002 compared to the decade before the beginning of Hep.B.vaccination, which is statistically significant (P=0.0029). Conclusion: Although there is no facility to measure antibodies in Iran and many other countries, and this is one of the reasons for lack of proof for existence of a relationship between vaccination and ITP incidence, the study of cases in two different periods may strengthen the role of Hep.B. vaccination in the occurrence of ITP at early infancy.
Alijan Rajabali, Dardi Qujeq, Mehrdad Kashifard,
Volume 8, Issue 1 (4-2008)
Abstract
Background & Objective: Many factors interfere in liver fibrosis one of which is hepatitis B.The aim of our study was to determine the parameters serum iron, TIBC and ferritin of patients with hepatitis B and fibrosis of the liver Methods: Study involved 50 cases with liver fibrosis and viral hepatitis type B (2002-2004)
and 26 controls. Iron concentration, Total iron-binding capacity and Ferritin concentration were measured by standard biochemical methods. To compare the results of the two groyps a student t-test was used and considering p< 0.05 the difference between two groups was significant. Results: The results showed that serum ferritin increase 243.7±16.7 micro gr/L and 238.7±13.9 micro gr/L in man and women patients with chronic hepatitis B virus infection compared to the control group, 198.5±14.3 and 182.7 ±14.3 mg/L in man and women, respectively. No significant difference was found between serum Iron and TIBC in both groups. there was a significant relationship between them. Conclusion: Increased serum ferritin concentration and liver fibrosis induced by hepatitis B virus infection. Also, determination of serum ferritin could help in diagnosis of liver fibrosis.
Mohammad Jafarzadeh, David Adham, Fatemeh Dana, Abbas Abbasi Ghahramanloo , Hossein Sharifi, Javad Abishvand, Reza Ebrahimoghli, Eslam Moradi-Asl,
Volume 23, Issue 1 (4-2023)
Abstract
Background & Objective: Hepatitis B virus [HBV] infection is one of the most important public health concerns. The present study was conducted to provide a descriptive analysis of detected HBV infection in Ardabil province.
Methods: In this retrospective longitudinal study, the hepatitis B surveillance database of Ardabil province was examined from 2014 to 2018. The frequency of hepatitis B virus infections was presented based on age, gender, marital status, place of residence, primary symptoms, and reporting sources. Also, the trend of changes in the number of detected cases over time was investigated using time series analysis.
Results: A total of 817 positive cases with a mean age of 43.1 years were reported. Most of them were male [n=503, 61.5]. The Frequency of identified positive cases decreased over time. Most of the infections were asymptomatic [87.5%]. Almost 90.0% of patients with HBV were married and the majority of the identified patients were resided in urban settings [n=598, 73.2%]. Most diagnostic tests were done voluntarily [n=219, 26.8%] or during prenatal care [n=109, 13.3%]. Most cases were identified and reported by the health network [n=292, 35.7%] and blood transfusion organization [n=190, 23.2%].
Conclusion: Decision-makers of the health sector of the province can use this information as a source for evidence-based decision-making in the effective management of the disease.
Corresponding Author:
Eslam moradi-Asl, Department of Public Health, School of Health, Ardabil University of Medical Sciences, Ardabil, Iran.
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