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Showing 2 results for Growth Hormone
Homeira Nasiri Rineh , Ferangis Khanpour,
Volume 13, Issue 3 (10-2013)
Abstract
Background & Objectives: Obesity is an important risk factor for many diseases and hormonal and metabolic factors have a great impact on its development. The aim of this study was to investigate the relationship between leptin and growth hormones with anthropometric indices and blood glucose in healthy men. Methods: This study is a cross-sectional study on 30 healthy adult men aged 18-49 years in Tonekabone city during 2011-2012. Samples were randomly selected and information on anthropometric parameters (waist circumference, body mass index and waist/hip ratio), fasting blood sugar, serum levels of leptin and growth hormones were recorded and blood sampling was performed After 12 hours of fasting (at 8 am). Data were analyzed using software SPSS 15 by non- parametric Mann – Whitney and Spearman test s and multiple regression analysis. Results: Serum leptin levels were negatively correlated with serum level of growth hormone ( P<0.05) and positively related to body mass index ( P<0.01) , waist circumference ( P<0.01) and the body weight ( P<0.05). Inverse relationship between serum growth hormone levels with age and fasting blood glucose were observed (P<0.05). Serum levels of leptin were significantly higher in overweight and obese than normal weight subjects (P<0.01) and mean leptin levels in subjects with central obesity ( waist circumference≥94cm) were significantly higher than men without central obesity (waist circumference<94cm) (P<0.01). Conclusion: This study showed that growth hormone level was negatively correlated with serum level of leptin. Low serum growth hormone and high serum leptin levels were associated with obesity and upper body fat distribution. Obesity and abdominal obesity are also associated with increased risk of metabolic syndrome
Behzad Azadi, Lotfali Boboli, Mostafa Khani, Marefat Siahkohian, Amaneh Pourrahim,
Volume 21, Issue 1 (4-2021)
Abstract
Background & objectives: Insulin-like growth factor -1 (IGF-1) has a variety of roles, but the abundance of scientific evidence indicates that it is a metabolic biomarker associated with physical fitness and health. The present study investigates the effect of eight weeks of polarized exercise training on serum GH / IGF-1- indices in active young men.
Methods: In this double-blind experimental study, 20 young males were allocated randomly into polarized training group (N=10) and a control group (N=10). The polarized training group performed 80-70% of the main workout volume (30 minutes) with light to moderate with 50-60% reserve heart rate (RHR) intensity and the remaining 20-30% at 85-95% RHR intensity; in a way that they ran two periods consisting 3 repetitions of 15-30 seconds, with 30-60 seconds of active rest after each repetition and 3 minutes of active rest after each period. Blood samples were taken from all subjects in three stages, including: pre-test stages, 24 hours before the start of the post-test, and after 12 hours overnight fasting. Post-test samples were collected, one sample immediately after the first session and the another 48 hours after the end of the last exercise session.
Results: The results of the present study showed that bipolar training significantly increased growth hormone and free IGF-I levels after one training session, and after eight-week bipolar training program. However, total IGF-1 levels decreased significantly after one exercise session and after eight-week bipolar exercise program. Also, no significant change was observed in IGFBP-3 and IGFBP-5 levels after one training session and eight-week training program. Acid-labile subunit levels did not change significantly after one training session, but decreased significantly after eight weeks of bipolar training.
Conclusion: Based on the results of the present study, it seems that the use of bipolar exercises, training may be a good way to improve the hormonal function and assess the level of health and physical fitness of active young men.
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