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Showing 6 results for General Anesthesia
Masoud Entezari-Asl , Mohammadreza Ghodrati , Hamid Ebadizare , Khatereh Isazadehfar , Volume 2, Issue 2 (6-2002)
Abstract
Background & objective : Recovery state or post - anesthetic awakening is one of the most dangerous anesthetic stages . Respiratory, cardiovascular and other complications such as nausea, vomiting, shivering, pain and restlessness have been reported . This study designed to investigate prevalence of this complications and its probable risk factors in Ardabil Fatemi and Alavi hospitals. Methods : In this prospective study, 160 patients were selected in Alavi and Fatemi hospitals during winter of 2001. We completed a sheath for everybody about their history of medical diseases, pervious history of anesthesia, addiction, drug abuse, smoking, physical class of ASA, type of anesthesia, time and place of surgery . Data was analyzed by SPSS software. Results : These results were obtained in patients after surgery in recovery room: shivering 36.3 % , pain 26.9 % , restlessness 21.3 % , respiratory complications 13.8 % , cardiovascular complications 12 % , nausea and vomiting 8.8 % . We found significant correlation between some risk factors with complications, e. g: shivering with history of medical diseases, drug abuse and place of surgery and so, pain with restlessness, respiratory complication and place of surgery . Conclusion : This study according to similar studies revealed higher prevalence of some of post - anesthetic complications as shivering, pain and restlessness in our samples .
Mohammadreza Ghodraty , Ghodrat Akhavan Akbari , Firooz Amani , Shahnaz Rahimi , Nasrin Shahab , Volume 3, Issue 3 (9-2003)
Abstract
Background & Objective : Regional anesthesia is a method of choice in cesarean section. But in emergency cesarean sections general anesthesia is usually preferred. On the other hand, intravenous sedative drugs used in general anesthesia induction rapidly crosses the placenta and result in fetal depression. Because of higher prevalence of general anesthesia in Iran it is reasonable to conduct more researches in this field. This study set out to compare the effects of Propofol and Thiopental-Na as induction agents on the neonatal Apgar score and maternal hemodynamic status. Methods: In this double blind clinical trial 60 pregnant women with ASA class I & II were studied. In a random way 30 patients received 2mg/kg Propofol and the rest of them were given 4mg/kg of Thiopental-Na. All these subjects had full term and normal fetus. Pre and post-induction status of the patients was monitored noninvasively after tracheal intubations and during 12 minutes after that. Also time intervals between induction and birth (cord clipping) and between uterus incision and birth were measured. Apgar score of neonates was evaluated through clinical examination in 1st, 5th, 10th and 15th minutes after birth. The data were analyzed in SPSS software using descriptive and analytical statistics such as T-test, chi-square and ANOVA. Results: Apgar score in different times (1.5,10&15 minute) had no significant difference between two groups. (In the 1st minute Propofol was 7.1 ± 2.2 and Thiopental was 74 ± 1.8, in the 5th minute Propofol was 9.2 ± 0.7 and Thiopental was 9.1 ± 0.9) Maximum variation of heart rate and blood pressure in two groups were not significantly different. The time intervals between induction and birth (less than 8 minutes) on the one hand and uterus incision and birth(less than 130 seconds) on the other were similar in two groups. Conclusions : Thiopental-Na and Propofol can be used with similar results for induction of general anesthesia in cesarean section.
Masuood Parish, Soosan Rassoli, Mohammad Reza Afhami, Farnaz Moslemi, Volume 5, Issue 2 (6-2005)
Abstract
Background & Objectives: Oculocardiac reflex (OCR) is presented with bradycardia and other arrhythmias, is induced by mechanical stimulation and therefore, encountered during strabismus surgery. The aim of this study is to determine the incidence and risk factors of cardiac arrhythmias during strabismus surgery in children and adults. Methods: In this prospective, randomized and double-blind study, 46 patients ASA class I and II underwent elective strabismus surgery with general anesthesia and were allocated to one of the two groups: children under 12 and adults over 12. All patients received standard general anesthesia based on their age. Demographic data, type of involved muscle, the incidence, (type and frequency) and the cause of arrhythmias and skillfulness of the surgeon (professor-assistant) were recorded. Results: There were 26 patients in children group and 20 patients in adult group. The overall incidence of arrhythmias was 91% with 96.15% in children and 85% in adults. There was not any significant difference in the incidence of arrhythmias, and the mean rate of occurence between two groups. Most of the arrhythmias were due to external ocular muscles traction. Conjunctival traction and pressure on the globe were the other causes. Stimulation of median rectus muscle as the most important arrythmogenic factor was seen in 13 children and 12 adults. Bradycardia and tachycardia were among common arrhythmias, but there was no significant difference between two groups (P>0.05) in terms of their incidence. Conclusion: This study showed that the incidence of arrhythmias during strabismus surgery is high in both children and adults. This reflex does not often lead to hemodynamic compromise, however, for its early diagnosis and treatment, close and continuous monitoring of the patient as well as cooperation and communication between anesthesiologist and surgon is needed.
Majid Pourshaikhian, Abdolhosein Emami, Rabiollah Farmanbar, Ehsan Kazam Neghad, Vadood Norouzi, Volume 10, Issue 2 (6-2010)
Abstract
Background and objectives: High incidence of postoperative shivering leads to complications such as increased oxygen consumption, intracranial & intraocular pressure and pain. Some drugs including pethedine, dexamethasone and doxapram are used for prevention of shivering. The aim of this study is to compare the effect of dexamethasone and doxapram in prevention of post-anesthetic shivering. Methods: This study is a double blind clinical trial including 90 patients in ASA 1 and 2 classes. The patients were under general anesthesia for elective abdominal and chest surgery with same the anesthesia techniques. Samples were randomly divided into three groups (two drug received groups and one control group). First group received dexamethasone 0.1 mg/kg, the second group doxapram 0.75 mg/kg and the control group 3 ml of distilled water as injection. The visible shivering observed after each treatment. Collected data were analyzed using Chi-square, Fisher exact and ANOVA tests By SPSS 16 and p ≤ 0.05 was considered significant. Results: Our results showed a significant difference between shivering in drug received and control groups. Shivering was significantly decreased in drug received groups (p = 0 . 05) but there was no significant difference between them. Conclusion: This study showed that both drugs of dexamethasone and doxapram are effective in prevention of post-anesthetic shivering and can be substituted with pethedine. In addition to antishivering effect, doxapram has a respiratory stimulant effect that is, that is clinically important in postoperative stage.
Mir Mohammad Taghi Mortazavi, Masoud Niazi, Naser Rezapour, Masoud Parish, Volume 15, Issue 4 (1-2015)
Abstract
Background & objectives: Surgery of upper part of femor in elderly patients can be due to the fracture of femoral neck, shaft and arthroplasty. Hemodynamic changes and complications of the anesthesia are among the major concerns. The aim of this study was to compare the hemodynamic changes in low dose isoflurane with propofol in upper femoral surgeries in elderly patients.
Methods: This prospective clinical trial study was done on 60 patients over 65 year-old elderly patients with ASA physical status of I and II that were candidate for upper femoral surgery in two groups (inhalational: isoflurane 0.5-0.6 MAC) and (total intravenous anesthesia with propofol 50-100 mic/kg/min). Hemodynamic changes were compared in these groups with the same anesthetic depth (HR-SBP-DBP-MBP-SaO₂).
Results: There was no significant difference in heart rate, age or sex between two groups. In isoflurane group SBP on 20 and 25th minutes and DBP and MBP on 20, 25 and 35th minutes were significantly higher than propofol group. In propofol group SaO₂ was significantly more than isoflurane group on induction, start of surgery and on 5, 25, 35 and 45th minutes of surgery.
Conclusion: In anesthesia with the same Bi-Spectral Index, isoflurane provides more stable hemodynamic parameters than propofol.
Mehrab Hojjat, Parviz Amri, Shahnaz Barat, Ali Bijani, Valiollah Amri, Volume 15, Issue 4 (1-2015)
Abstract
Background & objectives: This study was designed to compare the effect of general and spinal anesthesia on hemoglobin and hematocrit values in women following cesarean section.
Methods: This clinical trial study performed on 88 ASA class 1 pregnant women who were candidate for elective cesarean. Forty six patients received general anesthesia with isoflorane 0.75, N2O 50% and O2 and also 42 patients received spinal anesthesia with 12 mg of bupivacaine. The patients with a systemic disease or other causes of intraoperative excessive bleeding were excluded. All the operations were performed by same surgeon. Pre- and post-operative Hb and HCT values and Apgar score were recorded in both groups.
Results: Previous cesarean section history was the cause of surgery in 21 patients in group one and 22 patients in group two. Both groups were similar in age, weight, height and parity. The preoperative mean Hb or HCT values did not differ significantly between two groups. In both groups, postoperative mean Hb and HCT values were decreased significantly. Postoperative Hb and Hct reduction was significantly higher in general anesthesia group (p<0.05). There was no significant difference between two groups regarding Apgar score.
Conclusion: This study showed higher postoperative Hb and Hct reduction in general anesthesia than spinal anesthesia.
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