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Showing 2 results for Aerobic Training
Fahimeh Esfarjani, Fatemeh Rashidi, Seyied Mohammad Marandi,
Volume 13, Issue 2 (7-2013)
Abstract
Background & Objectives: Elevated apolipoprotein B-100 and decreased Plasma HDL due to hypertriglyceridemia are common abnormalities in insulin-resistant subjects that increase the risk of cardiovascular disease. The aim of this study was to investigate the effects of 8 weeks progressive aerobic exercise (AE) on blood glucose, lipidand lipoprotein profile, and aerobic power in adults with type 2 diabetes. Methods: Twenty nine women with type 2 diabetes (mean age 43.4 ± 1.7 years and blood glucose range of 150 to 230 mg/dl ) were divided into a control (n=14) and exercise (n=15) groups. Exercise group participated in an aerobic training program 3 times per week for 8 weeks. The intensity of aerobic exercise was 60–75% of HR max. The control subjects were asked not to alter their physical activity patterns. All subjects underwent anthropometric, lipid profile and aerobic power evaluation, at the baseline and 48 hours after last session training. Following a 12 h overnight fasting, a venous blood sample was drawn for the analysis of total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL), low-density lipoprotein (LDL), and (apoB100). Paired t test and analysis of covariance (ANCOVA) were used to analyze the data. Results: Significant improvement was observed in FBS, aerobic power, percent body fat, (Apo) B-100 and triglycerides (p< 0.05) for the exercise compared with the control group after training. No significant difference was observed in TC, LDL and HDL between two groups. Conclusion: According to our findings moderate intensity physical exercise can be effective in preventing the atherosclerosis via significant improvement in blood sugar, cardiovascular endurance, Apo B-100 and triglyceride in patients with type 2 diabetes.
Mehrdad Tashakkori Ghanbarian, Saeed Naghibi, Mohammad Shariatzadeh Jonaidi, Shahrzad Ansari,
Volume 21, Issue 4 (1-2022)
Abstract
Background & objective: FoxO1 and STRA13 proteins play an important role in duplication and cellular metabolism, regulation of cell differentiation, apoptosis and reducing the spread of fat tissue in the body. The aim of this study was to investigate the effect of different intensities of aerobic training on the expression level of FoxO1 and STRA13 genes in subcutaneous adipose tissue of male Wistar rats.
Methods: In this experimental study, 32 male Wistar rats with a mean age of 8 weeks and weight of 237±33 gr were selected, and they were randomly divided into 4 equal groups including moderate-intensity aerobic training (MIT), high-intensity aerobic training (HIT), high-intensity interval aerobic training (HIIT) and control group. The training program was implemented 8 weeks and 5 sessions per week for the experimental groups,. Adipose tissue biopsy was performed 48 hours after the last training session to evaluate FoxO1 and STRA13 gene expression using RT-PCR method. Data were analyzed using One-way analysis of variance test using SPSS 24 software at the significance level of p<0.05.
Results: The results showed that there was a significant difference in the FoxO1 gene expression level in the subcutaneous tissue of male Wistar rats between HIT and control groups (p=0.0001). However, no significant difference was observed between experimental groups. In addition, there was a significant difference in STRA13 gene expression level in the subcutaneous tissue between MIT (p=0.008), HIT (p=0.0001) and HIIT (p=0.009) groups and control group.
Conclusion: According to the results, aerobic exercise with variety of intensity is effective in controlling the genes expression rate involved in fat metabolism and by reducing the FoxO1 and STRA13 genes expression, they cause the duplication and reduce the expansion of fat tissue.
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