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Showing 582 results for Subject: Special

Zahra Fardiazar, Farzane Zahery , Sedige Sadegy Khamene , Sakine Mohammad Alizade , Hosein Kooshavar,
Volume 6, Issue 1 (4-2006)
Abstract

 

  Background & Objectives: Post-episiotomy perineal pain is one of the most common causes of maternal morbidity and is often poorly treated. This study was performed to investigate effectiveness, side effects and patient satisfaction when lidocaine gel and placebo are used.

 Methods: In this double-blind clinical trial a total of 124 women who had normal viginal delivery with mediolateral episiotomy without other complications were randomly selected to receive lidocain gel or placebo. Pain intensity was assessed by numerical rating scale (0-10) after perineal pain in different intervals. Pain relief was assessed by number of pain pills, amount of gel used and the degree of painlessness. Repair of episiotomy was assessed by physical examination on 1 and 10 days after delivery. The data were used to fill out a questommaire. Finally, these data were analysed by SPSS ll (rel 11).

 Results: There was no significant difference in the amount of pain pills taken, the amount of gel used and patients satisfaction between two groups. Regarding the healing of episiotomy there was no significant difference between two groups in the first and tenth day examinations and all wounds healed on 10th day. Satisfaction of the patients regarding the use of gel was the same in two groups.

 Conclusion: Despite the findings of some similar studies, topical gel of 2% lidocaine was not significantly different from placebo for healing eposiotomy and relieving its pain. But in both groups result of healing on 10 th day postpartum was good. More studies are required to indicate the effect of high dose of lidocaine on pain relief and the positive effects of using gel on wound healing.

 


Ali Majidpour, Shahram Habibzadeh , Firooz Amani , Fateme Hemmati,
Volume 6, Issue 1 (4-2006)
Abstract

  Background & Objectives: Acquired immunodeficiency syndrome (AIDS) with a history of only three decades, has turned into a threatening pandemic disease world wide giving rise to 3.1 million deaths in 2005. Since there is no distinctive treatment or effective vaccine for AIDS, its epidemiology is similar to non-communicable and behavioral diseases. Since accurate knowledge and attitude is necessary for a healthy behavior, we conducted this study on high school students of Ardabil to determine their sources of acquiring information on AIDS as well as to find out their attitude and knowledge about this disease.

  Methods: This descriptive and cross-sectional study was conducted on 800 students in Ardabil high schools during the year 2002 using cluster random sampling method. A questionnaire with 4 groups of questions including demographic information, source of information used for AIDS and the amount each source is used as well as attitude and knowledge of the participants regarding AIDS was distributed in the school. The collected data were analyzed using SPSS.

  Results : 378 (47.2%) out of 800 students were girls and the rest of them were boys. The media used for getting informed about AIDS was determined to be: 84.5% TV, 51.4% newspapers and magazines, 49.6% papers and books and 30.6% radio. 89% of the girls and 67% of the boys used TV. The difference was statistically significant(p<0.001). Sources of information in interview form were found to be health care workers with 17.7%, teachers with 10.2%, friends with 9.5%, religious authorities with 8.6%, family members with 8% and other relatives with 5.6%. A combition of the above-mentioned methods plus other souces formed 41.3% of the information source of the students about AIDS. Only 46.3% of the students had a proper insight in their interaction with role-playing patients of AIDS. 44% of the participants had weak and 56% had moderate knowledge about transmission ways of HIV and no one had good knowledge in this regard. There was no significant difference between age, sex and knowledge. The highest percentage of moderate knowledge score was seen in student studying experimental sciences. Only TV had a significant correlation with knowledge (p=0.001).

  Conclusion: This study entails that more attention must be paid to education through effective use of TV broadcasting. Films, pictures, teachers, clergymen, radio, books and papers had not an effective educational role among high school students regarding AIDS.


Mahrnaz Mashoufi, Khalil Rostami, Afrooz Mardi ,
Volume 6, Issue 1 (4-2006)
Abstract

  Background & Objectives: With respect to the importance of observing principles of documentation of medical records for educational, treatment, research, legal and statistical uses, the correct, complete and timely registration of this information can play a crucial role in the production of necessary data for these kinds of researches. This study was performed to investigate the process of documentation of medical records of the patients in hospitals under Ardabil university of medical sciences.

  Methods: In this research 370 medical records from eight hospitals under Ardabil university of medical sciences were studied. In each hospital samples were selected randomly based on the number of patients hospitalized in one year. Then according to admission and discharge sheets a certain checklist was completed. The information under study included dignosis, treatment, surgery, cause of the accident, patient condition on dircharge, postdischarge advice and cause of death (whether recorded or not) which were identified in the check list. The data were analyzed by SPSS using descriptive statistics.

  Results : The findings showed that primary, interim and final diagnosis and treatment measures were recorded 71.9%, 58.9% ,60.8% and 52% respectively in the records studied. Althougt 12.7% of these patients were hospitalized dueto accidents, damage and poisoning, only in 8.5% of them the external causes were recorded. In 68% of the records, condition on discharge and in 76.3% of them recommendation on discharge had not been recorded. 3.5% of the records were related to dead patients, but only in 31% of them the main cause and in 8% underlying cause of death was recorded. In general, in 5 2.4% of these records the correct methods of medical recording were not observed by physicians.

  Conclusion: The results indicated that the process of documentation of medical record by physicians as the main presenters of health care services was performed incompletely. This can lead to the loss of valuable information about the hospitalized patients. It can also have negative impacts on the course of therapy. As a result, the authorities, physicans and specialists in medical recording should pay special attention to this problem.


Maziar Hashemilar, Daruoosh Savadi Oskoui , Mariam Jafaryani , Naiere Aminisani,
Volume 6, Issue 1 (4-2006)
Abstract

 Background & Objectives: The ischemic stroke is defined as cerebral dysfunction due to brain infarct which is induced by vascular obstruction. The related risk factors including hypertension, diabetes mellitus, cardioembolism and hyperlipidemia are investigated in several studies. The aim of this study was to determine the etiology of cerebral infarction in young adults ( - year-olds).

 Methods: All the patients in the age rang of - admitted to the neurology ward of Alavi Hospital in Ardabil between 2004 and 2005 with a diagnosis of cerebral infarction were included in this study. A questionnaire including demographic data, personal and family history of stroke and cardiac infarct, hypertension, diabetes, smoking and hyperlipidemia was filled out for all patients. Blood sugar, cholesterol, anticardiolipin antibody and beta- glycoprotein were examined. The patients underwent echocardiography. The data were analyzed using SPSS software (release ).

 Results: The total number of the patients was , including females (71.1%) and males (28.9%). The mean age was (SD= ). The etiologic factors based on their frequency were: cardioembolism ( ), positive antiphospholipid antibodies (35.5%), hyperlipidemla ( ), smoking ( ), hypertension ( ), oral contraceptive use ( ) and diabetes mellitus (13.7%).

 Conclusion: The most frequent etiologies of the cerebral infarcts in the young adults in this study were cardiogenic embolism and positive antiphospholipid antibodies. Other background factors were hyperlipidemia, smoking, hypertension, oral contraceptive use and diabetes mellitus respectively. Most of these etiologies can be intervened and prevented. The identification of these factors before occurrence of cerebral infarction can prevent this debilitating event.


,
Volume 6, Issue 1 (4-2006)
Abstract

  Succinylcholine is a depolarising muscle relaxant that is used for rapid tracheal intubation in general anesthesia. It is a short-acting drug which is hydrolyzed by plasma cholinesterase. Some factors can decrease the activity of this enzyme in body. Some patients may have abnormal form of this enzyme that leads to prolonged duration of action and apnea. The subjects of this research were a male (55) and a female (57) who had prolonged apnea after administration of succinylcholine (4-8h), and they improved completely after mechanical ventilation.


Abbas Abolghasemi, Azar Kiamarsi,
Volume 6, Issue 2 (6-2006)
Abstract

 Background & Objectives: The cognitive processes such as attention, thinking, memory and recall have effective role on the child’s confrontation with daily life problems. The psychological disorders are among those impairments which may severely affect these processes. Researches have shown that schizophrenia can impair children’s cognitive processes to a great extent. The aim of this research was to compare the comprehension, lexical Knowledge, memory and recall in children with schizophrenia, conduct disorder and brain damage.

 Methods: The sample of this causal-comparative research consisted of 80 children (8-13 years old) suffering from schizophrenia, brain damage and conduct disorder as well as a group of healthy ones who were selected from among in and out-patients referring to psychology and neurology wards of Emam Hossein health care center in 2004 (20 subjects in each group). The instruments employed in this research were WISC-R (comprehension, vocabulary, digit span) and Recall Test of Babcoch.

  Results: The one way analysis of variance showed significant differences between the children with schizophrenia, conduct disorder, brain damage and non-patient in comprehension, lexical knowledge, memory and recall (p<0.01). The LSD test showed that comperhension, lexical knowledge, memory and recall in children with schizophrenia were more impaired compared to children with conduct disorder and brain damage. Moreover, comprehension, lexical knowledge and memory in children with conduct disorder were more severely impaired than children with brain damage. However, the recall was better in children with conduct disorder than those with brain damage (p<0.01).

 Conclusion: The results showed that schizophrenic children have comprehension, lexical knowledge, memory and recall more impaired than those suffering from conduct disorder and brain damage. The timely recognition of the cognitive abnormalities seems necessary to have a better diagnosis and choose effective treatment and remedial strategies to cope with them.


Gholam Hosein Ettehad , Ali Hosseinkhani , Elias Hashemi ,
Volume 6, Issue 2 (6-2006)
Abstract

  Background & Objectives: Urinary tract infections (UTI) are among the most common bacterial infections in humans. One of the most frequent form of UTI is asymptomatic bacteriuria. The aim of this study is to determine the prevalence of asymptomatic bacteriuria in female students of Babol Islamic Azad University.

  Methods: This research was carried out on 207 female students from Babol Islamic Azad University in 2002. The age ranges of the students were between 18-29 years. Mid-stream urine (MSU) was collected from students. Urinalysis and bacteriological identification culture of MSU were done twice on all specimens. The prevalence of asymptomatic bacteriuria was determined by dividing the total number of observed bacteriuria by the total number of samples.

  Results: Bacteriological tests of MSU revealed that 19 (9.2%) cases were positive for asymptomatic bacteriuria. The microbe most frequently causing asymptomatic bacteriuria was staphylococcus saprophyticus in 7 (36.8%) cases Escherichia coli in 6 (31.6%) cases and Klebsiella in 3 (15.8%) cases.

  Conclusion: Asymptomatic bacteriuria was highly prevalent in our study. Therefore, young women must consider general health rules about genitourinary system to avoid asymptomatic bacteriuria.


Ahad Azami , Abbas Yazdanbod, Nateg Abbasgolizadeh, Yegane Sadeghy,
Volume 6, Issue 2 (6-2006)
Abstract

  Background & Objectives: According to a recent report published by the ministry of health, Esophageal cancer is the second most common fatal cancer in Ardabil. This study investigated the relationship between anatomical sites and pathological features of Esophagus cancer with related risk factors.

  Methods: This descriptive-cross-secional and prospective study was conducted on patients referring to GI clinic of Ardabil (Aras) between 2000-2003. Patients with suspicious upper GI symptoms underwent upper GI vide-endoscopy. At least five to six endoscopic punch biopsies were obtained from all the lesions and sent for pathology. Diagnosis was confirmed by pathology. Anatomical sites, demographic information of the patients (age, sex, educational state, residential area) smoking habit, alcohol and opium consumption were entered into the questionnaire. Statistical analyses were performed using the EPI 2000 statistical software.

 Results: The mean age of the patients with cancer was 59 ± 11.64 years and the male to female ratio was 1:1. Villagers constituted 117 (77%) of the patients. 93.4% of these patients were illiterate. The cancers were of the following types: 126 (82.9%) SCC, 25 (16.4%) adenocarcinoma and 1(0.7%) in situ carcinoma. The most common site of esophageal SCC cancer was middle third of esophagus with 73 (48%) patients. In contrast the most common site of adenocarcinoma in 31 (20%) patients was lower third of esophagus. No meaningful relationship was found between esophageal cancer and smoking drinking or opium consumption.

  Conclusion: The findings indicated that unlikewestern countries esophagus cancer had no relationship with smoking or alcohol consumption in Ardabil. Other studies are recommended to be performed to find out more about relationship between known esophageal risk factors including nutritional habits, nitrosamines, soil contents, agricultural products and genetic background.


Nader Pashapour, Ali Macooei , Vahid Sheikhi ,
Volume 6, Issue 2 (6-2006)
Abstract

  Background&Objectives: Febrile convulsion is a disease with good prognosis but its mismanagement leads patients to serious complications. T his study was conducted to compare practice guidelines with current practices in the management of children with first febrile convulsion.

  Methods: This descriptive-analytical study was conducted on patients hospitalized with the diagnosis of first febrile convulsion in Imam-Khomeni hospital of Urmia in 2004. The data were collected from their hospital records. Practice guidelines of the American Academy of Pediatrics (AAP) were employed as reference. Current practices were compared with AAP recommended practice parameter about simple febrile seizure. Investigations performed included lumbar puncture, complete blood count, CRP, ESR, blood glucose, serum calcium, serum electrolytes, renal function tests, urinalysis, urine, and blood culture, chest X-ray, EEG and CT scan.

  Results: T wo hundred fifty one cases aged 6-60 months were studied. Complete blood count, ESR, CPR, blood glucose, serum calcium, serum electrolytes, renal function tests, urinalysis, urine culture, and blood culture in all cases (100%), lumbar puncture in 10%, chest X-ray in 24%, EEG in 1.4% and CT scan in 0.65% of cases were the measurements conducted.

  Conclusions: The present study showed that the use of unnecessary investigations was common. Investigations, though costly, proved to be of little diagnostic value. This problem can be alleviated through a well-organized national program or observing AAP practical guidelines.


, , , ,
Volume 6, Issue 2 (6-2006)
Abstract

Background & Objectives: Coronary artery diseases and acute myocardial infarction are among the most common causes of death worldwide. Revascularization techiques have a major role in the management of this disease. Thrombolytics especially stereptokinase have been widely used because they do not require any expertise. Stereptokinase therapy may cause reperfusion of infarct area which in turn can result in arrhythmia. This study was performed to determine the sensitivity and specificity of developing reperfusion arrhythmias in predicting left ventricle function in patients with anterior myocardial infarction.

Methods: This descriptive and cross-sectionel study was conducted on 100 patiens with acute anterior myocardial infarction who were admitted to CCU ward of Buali hospital and received stereptokinase. The patients with history of heart failure and contraindication to stereptokinase therapy and patients who had died in the first 6 hours of myocardial infarction were excluded from the study. During the first 24 hours after admission echocardiography was performed for obtaining left ventricle ejection fraction. The data were gathered and analyzed with SPSS saftware using descriptive and inferential statistics.

Results: 52% of the patients encountered arrhythmia during receiving stereptokinase,  33% of whom had normal left ventricle function and 19% encountered significant dysfunction of left ventricle. From remaining 48% who didn’t encounter arrhythmia, 21% had normal function of left ventricle and in the rest of them it was impaired.

Conclusion:This study showed that the creation of arrhythmia due to reperfusion can predict the consistency of LV functioning with a sensitivity of 61% and a specificity of 58%. Moreover, there is a meaningful relationship between reperfusion arrhythmia and continuation of left ventricle functioning after treatment with streptokinase.


Mahzad Sadaghiani , Hale Ayatollahi , Fariba ; Nanbakhsh , Atoosa Mojahadieh,
Volume 6, Issue 2 (6-2006)
Abstract

  Background & Objectives: Infertility affects approximately 10-15% of reproductive age couples. Intra Uterin Insemination (IUI) is a primary, simple and effective method of infertility treatment in ovulatory disorders, unexplained infertility, cervical factors and some cases of male factor. In this research, the success rate of IUI with regard to different causes of infertility was studied in Kowsar IVF centre.

  Methods: In this retrospective study, 404 infertile couples were studied using a questionnaire that included the demographic data, duration of infertility , sperm count and mobility, follicular diameter and count, situation of uterus and fallopian tubes and pregnancy results. The data were analyzed with SPSS.

  Results: Pregnancy rate was 11.1% for patients with ovulatory factors and 7.1% for male factors. There were no significant differences in sperm count and diameter of follicles in pregnant and nonpregnant women.

  Conclusion: With regard to different causes of infertility the best treatment results were achieved by IUI in ovarian factor. Patients over 35-40 did not have a good prognosis in COH-IUI cycles. Other methods of ART are recommended in such cases.


Reza Ali Panah Moghadam , Mohamad Rahbani Nobar ,
Volume 6, Issue 2 (6-2006)
Abstract

 Background & Objectives:Lipid peroxidation has recently attracted considerable attention. It has been linked to carcinogenesis, aging and variety of other diseases including atherosclerosis. Atherogenesis involves the complicated interaction between cells of the arterial wall and lipoproteins (mainly oxidized LDL). The aim of this study was to investigate the relationship between serum malodialdehyde (MDA), the important indicator of lipid peroxidation and alteration in serum lipids and lipoproteins concentrations in male patients with coronary artery disease (CAD).

  Methods: The subjects of this study were 51 male patients under 55 with angiographically comfirmed CAD admitted to Shahid Madani Hospital and 60 age and sex matched apparently healthy individuals as the control group. The serum level of MDA was measured by colorimetric method using thiobarbituric acid reaction and lipid and lipoproteins concentrations were determined by standard enzymatic methods.

  Results: Significant elevation in the level of MDA was noticed compared to the controls (P=0.03) . Serum concentrations of cholesterol, triglyceride, LDL-C and LDL - C /HDL - C ratio in cases were higher than those of the controls (P=0.03) . There was a positive and significant relationship between serum MDA and biochemical risk factors including Triglyceride, Cholesterol, LDL-C and LDL - C/HDL - C ratio (p=0.03). The correlation between serum MDA and serum HDL-C was negative and meaningful (P=0.03) . No relationship was observed between serum MDA with BMI and age in cases.

Conclusion: Simultaneous control and monitoring of both dyslipoproteinemia and lipid peroxidation may be of equal importance in prevention of occurrence and progression of CAD.
Mohammad Ali Mohammadi, Behrouz Dadkhah, Hashem Sazavar , Naser Mozaffari ,
Volume 6, Issue 2 (6-2006)
Abstract

  Background & Objectives: Controlling diet to regulate blood pressure in hypertensive patients has always been a challenging issue. On the other hand, insufficient supporting systems, non efficient follow-up programs, patients inability to do treatment measures in relapsing period, insufficient following of diet and drug taking, unplanned discharge and poor knowledge of risk factors are among controllable factor that lead to the readmission of the patients. The aim of this study is determining the effect of follow up on blood pressure control in hypertentive patients.

  Methods: In this interventional study, hypertensive patients referring to emergency ward were randomly divided into two case groups (100 patients) and two control groups (100 patients). After collecting data, case group patients were trained in their homes about the role of nutrition, mobility and regular drug use in blood pressure control for 3 months. Then, blood pressure in case and control groups was controlled and mean blood pressure in two groups was compared. The collected data were analyzed by SPSS software using descriptive and analytical statistics.

  Result: 55.4 % of the case and 54.3% controls had family history of blood pressure. Before intervention mean BMI in case and control group was 26.8±5.56 and 28.04±14.66 and after intervention it was 25.96±5.38 and 27.61±14.29 respectively. Before follow up program was implemented, 39.13% of the cases and 35.87% of the controls had regular drug use history. After follow-up this rose to 44.6% and 42.4% respectively. After follow-up program 22.83% of the cases and 17.39% of the controls had referred to emergency ward or a physician once in 3 months. After intervention program, mean systolic blood pressure in cases and controls were 133 and 153 mmHg respectively and this difference was statistically meaningful (P<0.001). After follow-up, systolic blood pressure control in case and control groups was 59.8% and 35.9% respectively and this difference was meaningful (P<0.001).

  Conclusion: Results showed that after training program and home follow-up, blood pressure and weight control were more in case group, than control group, Therefore, we suggest that patient training programs and follow up and home follow-up be used as an effective way in hypertensive patients' health care and their treatment.


Mahdi Farhoudi , Mohammadkazem Tarzamani , Khandan Ghannadi Emami ,
Volume 6, Issue 2 (6-2006)
Abstract

  Background & Objectives: Cerebrovascular diseases are the most common disabiling neurologic disorders and the third cause of death in the population over 45 years of age. Most of the strokes in adults are ischemic and almost one-fifth of them are due to intra- or extracranial internal carotid artery stenosis. Ultrasonography is a noninvasive, cost-effective and safe technique for evaluation of intra or extracranial vessels that is available in two methods: TCD and carotid Duplex. The present research is an attempt to investigate the appropriatens and comprehensiveness of TCD in diagnosing symptomatic significant carotid stenosis.

  Methods : This descriptive-analytical study was conducted on fifty patients admitted to the neurology ward of Imam Hospital who underwent both carotid duplex and TCD examination. Variables of blood flow velocities, collateral flow evidences and degree of carotid stenosis were assessed with both methods. The data were analyzed by SPSS (ver.11.5) using T.test, Chi-square and Fisher test.

  Results : 34 patieuts were. Male mean age of the patients was 66.70% of the subjects were above 65 and 68% of them had a history of hypertension. No statistically significant difference was seen between systolic and diatolic blood flow velocity in internal carotid artery and pulsatile index obtnined from reported by TCD and carotid Duplex. There was no statistically significant difference between the percentage of stenosis TCD finding of the patients with carotid stenosis showed collateral flow in 78.57% of the cases.

  Conclusion: Acceptable correlation of the flow velocity parameters and the percentage of carotid stenosis between TCD and Carotid Duplex results showed that the primary performance of TCD to diagnose significant carotid stenosis (that causes hemodynamic disorder) and screen ischemic cerebrovascular accident is a reliable and effective method, but for precise determination of stenosis, plaque typing and for diagnosing stenisis below 50% the performance of carotid duplex study is also necessary and to complemantory TCD.


Faride Golfooroshan, Effat Khodaeiani , Shahla Babaei Nejad , Delara Laghosi,
Volume 6, Issue 2 (6-2006)
Abstract

  Background & Objectives: Diabetes mellitus (DM) is a clinically and genitically heterogeneous group of disorders characterized by abnormally high levels of glucose in blood. The skin is involved both in the effects of acute metabolic changes and in the chronic degenerative compilications of diabetes. Skin lesions are frequently observed in diabetic patients and it is generally stated that about 30% of these patients have cutaneous disorders. The aim of this study was to assess the prevalence of skin lesion in patients with diabetes mellitus referring to dermatology and diabetes clinic of Sina hospital in Tabriz .

  Methods: This descriptive-analytical study was conducted on diabetic patients with skin lesion who referr e d to diabetic and dermatology clinic of Sina hospital of Tabriz during 2003. Data collecting instrument was a questionnaire which included some variables such as age, sex, job, type of diabetes, its duration, control of blood glucose, receiving regular treatment, type of lesion. The questionnaire was filled out for each patient with skin lesion individally. Skin lesions due to burn were excluded from our study. The data were analyzed by SPSS using Chi-aquare and Fisher test.

  Results : From a total of 500 patients, 80 patients (16%) had skin lesions. 57.5% of these patients was male and 91.2% had type II DM. Mean age of the patients with skin lesion was 56.86±1.54 years and mean diabetes duration was 10.87±0.82 years. Patients over 50 years had the most skin lesion . The most common type of skin lesion in the diabetic patients were 30 cases of necrotic ulcer (6%) and 22 cases of diabetic dermopathy (4.4%) respectively. Other skin lesions such as infection, sclerodermoid, punched out lesions, neuropathic ulcer, diabetic bulla, dermatitis and lichen planus were not common . 97.5% of diabetic patients with skin lesion had poor control of blood glucose. Twelve percent of the patients had some kind of diabetic foot ulcer (Neuropathic Necrotic, punched out and cellulitis ulcer altogether) of which 21.6% underwent amputation.

  Conclusion: The results showed that rate of skin lesions in diabetic patients is decreased. compared to the past. This may be due to increase of knowledge and attitude of patients regarding diabetes and its complications.


Behnam Mohammadi Ghalehbin, Esmaeil Falah , Mohammad Asghar Zadeg, Abdol Hasan Kazemi, Ahmad Daryani, Firooz Amani, Saeide Amani, Mina Agazade, Rasool Abdollahi, Rouhollah Arab,
Volume 6, Issue 2 (6-2006)
Abstract

 Background & Objectives: Cryptosporidium is an intracellular – extracytoplasmic parasite that has taken much attention in last 20 years as a clinically important human pathogen. Cryptosporidial infection can be transmitted from fecally contaminated food or water and from animal-human or human-human contact. In immunocompromised persons, the illness is much more severe such as debilitation, fatigue, cholera-like diarrhea, severe abdominal cramps, low-grade fever, severe weight loss and Anorexia. Because there was no regional study about cryptosporidiosis in Ardabil, we carried out this survey to determine the prevalence of cryptosporidiosis among the children hospitalized in Ardabil.

 Methods: This descriptive and analytical study was carried out on 371 patients in Sabalab and Aliasghar hospitals of Ardabil between 2004 and 2005. A questionnaire was filled for each patient. Stool samples were examined by concentrated formal - ether method and stained with modified Ziehl-Neelson method. The data were analyzed with SPSS (ver 11) using Chi-square test.

  Results: We analyzed 371 stool samples from children with diarrhea. Cryptosporidium oocysts were detected microscopically in 15 samples. Its prevalence was 4.04% in infected patients. 66.7% of the infected ones were at the age of 6 to 24 months, 20% 25-48 months, and 13.3% 49-72 months.

 Condusion: Because cryptosporidiosis was more prevalent at the age of 6-24 months, health education is more necessary for their mothers.


,
Volume 6, Issue 2 (6-2006)
Abstract

  Background & Objectives: Diabetes mellitus may be associated with the imbalance between protective effect of antioxidants and increased free radical production with regard to discrepancies of the findings in previous researches the present study set out to determine the changes of plasma malondialdehyde and erythrocyte antioxidant superoxide dismutase activity in patients with type II diabetes mellitus.

  Methods: This case-control study was conducted in 2005 using random sampling. 38 patients with type II diabetes mellitus who referred to 5th Azar diabetes center and 19 age and sex matched healthy controls were selected for this study. Heparinated blood samples were taken from the cases. The separated plasma was tested for blood sugar, lipid peroxidation and blood cells (for glycolisated Hb and superoxide dismutase enzyme activity). The collected data were analyzed by SPSS (ver. 10) using t-test.

  Results: The level of plasma malondialdehyde from type II diabetes mellitus patients (6.27±0.80 nmol/ml) was significantly different from that in control group (3.56±0.98 nmol/ml)(p<0.05). Erythrocyte superoxide dismutase activity from type II diabetes mellitus patients (678.78±59.36 U/gr Hb) was significantly lower than control group (1056.47±52.98 U/gr Hb) (p<0.05).

  Conclusion: The significant difference between the increase in malondialdehyde and decrease in the activity of antioxidant enzymes in patients with type II diabetes mellitus may predispose to the development of serious complications leading to cellular damage. This suggest that diabetic patients may need more antioxidants than normal. Supplementation with medical or non-medical free radical scavengers such as vitamins E and C or foods untaining vitamin C (sitrus fruits) have a potential role in reinforcing antioxidant defence and can be important in diabetic patients.


Mohammad Narimani , Yoosof Khonya , Abbas Abolghasemi , Masoud Ganji , Gafar Majidi ,
Volume 6, Issue 2 (6-2006)
Abstract

 Background & Objectives: Clinical findings show that stress can gradually affect the activity of various systems of the body such as immune system and impair them. Different variables potentiate and modify this effect. This research aimed at studying the relationship of personality traits (self-respect, tenacity, type A personality), stress, and stress coping skills with immune system status in nurses.

 Methods: In this descriptive-analytical study, 246 individuals were selected by simple random sampling method. At the first stage, the subjects on the job completed the questionnaires of self-respect, tenacity, type A personality, stress, and stress coping skills. At the second stage to determine the amount of antibodies, 2-cc blood of the subjects was assessed. The data were analyzed using correlational methods.

  Results: The findings indicated a significant, positive and meaningful relationship of immunoglobulin antibody with “self-respect”, and IgM antibody with “type A personality” in male nurses (p<0.05). But there was no significant relationship between the immune system variables and tenacity, stress, and stress coping skills. From among the predictive variables (self-respect, tenacity, type A personality, stress, and stress coping skills) only the stress variable had significant relationship with the criterion variable (IgA antibody)(p=0.05).

 Conclusion: Regarding the results it can be said that self-respect may adjust IgG variable in stress positions (especially in chronic stress). So in hard jobs such as nursing, psychological characteristics should be considered as an important job factor along with physical capabilities.


Farhad Salehzadeh , Dina Emami , Aliasghar Zolfeghari , Abbas Yazdanbod , Shahram Habibzadeh , Bahman Bashardoost , Manoochehr Barak , Eiraj Feizy , Hormoz Azimi , Marina Jastan , Jafar Khalafi ,
Volume 6, Issue 3 (9-2006)
Abstract

 Background and Objectives: Familial Mediterranean fever which is the prototype of the hereditary periodic fever syndromes is common in the countries around the Mediterranean Sea. Regarding the geographical position of the northwest of Iran, having Turkish originality and its vicinity to the Mediterranean Sea , the incidence of this disease is significant in Ardabil. The goal of this study was to introduce Familial Mediterranean Fever as a disease with significant outbreak in this area.

 Methods: This research is a descriptive study which has been done during one year from October 2004 to October 2005. According to the Tel-Hashomer criteria, the patients suffering from Familial Mediterranean Fever were collected from private clinics and pediatric rheumatology clinics records. Then from 112 patients only 74 ones were studied. All of the patients were interviewed and filled out a questionnaire.

 Results: Familial Mediterranean fever is common among children under 18 (76%) and more common in male than female. Abdominal pain has been the most common complaint (74%) and abdominal pain and fever (95% and 84% respectively) were the main clinical symptoms. The most common period of pain was 12-72 hours and the common recovery (attack free) period was from 1 week to 1 month (63/5%). Majority of the patients had hospital admission for diagnostic work up (85%) and some of them (32%) had been under surgical operation mistakenly. On the whole 92% of the patients had taken medications as a result of wrong diagnosis and 20% had positive familial history. 50% of the patients' parents were first degree relatives and in 59.5% delay in diagnosis was more than 3 years.

 Conclusion: Results of this study and introduction of this group of patients in a one-year research indicate that: Familial Mediterranean Fever is more common in the Northwest of Iran although physicians are not familiar with that. The common age for manifestation of this disease is under 18 and its presentation after the age of 40 is very rare.


Ghodrat Akhavan Akbari , Masoud Entezariasl , Firooz Amani ,
Volume 6, Issue 3 (9-2006)
Abstract

  Background and Objectives: Laryngoscopy and tracheal intubation could lead to hemodynamic responses in the from of hypertension and tachycardia as well as arrhythmia and myocardial ischemia. This alterations can be life-threatening particularly in elderly people. This clinical trial compared the effects of two rapid-onset narcotics, Alfentanil and Remifentanil, on the hemodynamic responses to the induction and tracheal intubation in elderly patients.

  Methods: This double-blind clinical trial was conducted on 40 subjects aged 65 and above. They were candidate of cataract surgery under general anesthesia. The patients were randomly allocated to two groups of 20. The first group, was gaiven Alfentanil 10 m g/kg and for second group Remifentanil 0.5 m g/kg was injected prior to the induction of anesthesia. Both groups were similiar in the method of anesthesia except in narcotics. The first group was infused with Alfentanil 1 m g/kg/min and Remifentanil 0.1 m g/kg/min was used for the second group. Hemodynamic variations including heart rate, systolic, diastolic and mean arterial blood pressure were measured and recorded eight times (before induction, aften injection, after intubation and five times during anesthesia). Data were analyzed with SPSS software using descriptive and analytical statistics such as T-test, chi squre and ANOVA.

  Results: Immediately after injection of narcotic drugs, all hemodynamic variants decreased. Howerver diastolic blood pressure in Remifentantil group significantly more than Alfentanil group (P<0.05). After laryngoscopy and tracheal intubation all hemodynamic variants increased and slowly decreased in less than 10 minutes. Systolic, diastolic and mean arterial blood pressure decreased significantly in remifentanil group than alfentanil group (P<0.05). Although heart rate decreased during few minutes after intubation, there was not significant difference between two groups regarding this decrease (P>0.05). Ephedrin was used to treat severe hypotention in those under Remifentanil (11 patients) more than those under Alfentanil (4 patients) (P<0.05).

  Conclusions: According to the resukts of this study Remifentanil could prevent hemodynamic variation induced by laryngoscopy and treacheal intubation more than Alfentanil. However in some cases Remifentanil leads to hypotension during anesthesia. There is no important difference between two drugs in increasing heat rate after laryngoscopy and intubation.



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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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