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Showing 885 results for Type of Study: article
Seyed Alireza Ayatollahi , Asghar Mohammadpoor Asl , Abdolreza Rajaee Fard , Volume 4, Issue 4 (12-2004)
Abstract
Background & Objective: Previous studies have suggested that early smoking initiation predicts the duration of smoking, its daily consumption and increased chances of nicotine dependence. The peresent study was an attempt to determine the psychological predictors of transition in different stages of cigarette smoking. Methods: A total of 1132 students in 45 school classes were assesed two times, 8 months apart (Age range: 14-19). The subjects filled out a questionaire about cigarrete consumption behavior and predictor variables. 8 menths later they completed a second questionnaire regarding the cigarette consumption. The data were analyzed using logistic regression. Results: Among non-smokers, using alcohol was a predictor of experimenter smoker whereas positive attitude toward smoking predicted regular smoker. Drug abuse and positive attitude toward smoking set out to be strong predictors of transmission from experimenter smoker to regular smoker. Conclusion: Smoking prevention should begin during and before high school period. This study may support interventions that aim at changing high-risk behaviors.
Abbas Aflatoonian , Hajar Hojat , Nasim Tabibnejad, Volume 4, Issue 4 (12-2004)
Abstract
Background & Objective: Ectopic pregnancy (EP) is the most common cause of maternal mortality in the first trimester. 10% of maternal death is due to EP and only one-third of women with previous ruptured ectopic pregnancy could have a normal delivery in future. Research about prevalence and risk factors of this kind of pregnancy, could help early diagnosis and treatment of EP and improve the prognosis of fertility rate in the future. Methods: In this retrospective, descriptive and cross-sectional study, seventy-two patients with EP diagnosis admitted and treated in Yazd hospitals were studied. The data were collected using a questionnaire and hospital records. Sonography and laparoscopy confirmed the diagnosis. The data were analyzed by SPSS using Chi-Square test. Results: 11176 pregnancies were recorded in Yazd between March 1999 and March 2000 and seventy-two of these pregnancies were ectopic. So prevalence of EC in yazd was found to be 0.5%. Most of the patients (58 cuses) were 20 to 39 years old. 52.8% of the patients had primipar. 25% had a history of one to three times abortion. From 43 patients who used contraceptive, 19 ones used OCP (oral contraceptive). 39 patients had a history of previous surgery, 7 patients had a history of EP and 25 patients had a history of treatment of infertility. The most common symptom of patients was abdominal pain. Only 4 out of 72 patients were treated with a medical method using methotraxe and the rest of them were operated. Three out of these four patients were finally obliged to undertake surgery. Conclusion: The prevalence of EP was 0.5%, which is lower than the national scale.
Farnaz Ehdaivand, Masoumeh Rostamnejad , Effat Iranijam , Volume 4, Issue 4 (12-2004)
Abstract
Background & Objectives: Hypertension is the most common medical problem in pregnancy, with an incidence rate of 6-8%. The patients with preeclampsia are exposed to more maternal and fetal complications. This requires more intensive prenatal cares. The diagnosis in early stages of disease has an important role in decreasing maternal and neonatal mortality and its comsequent complications. This study was an attempt to determine the epidemiological factors and complications of preeclampsia among patients admitted to Alavi hospital, Ardabil. Methods: This descriptive retrospective study was conducted on 176 women with preeclampsia. The data were collected using a questionnaire and medical records of patients. These data were analyzed using descriptive and inferential statistics. Results: 75% of the patients had severe preeclampsia and 25% had mild preedampsia. Regarding the predisposing factors, history of preeclampsia was observed in 23.1% of the cases, mother's underlying diseases in 12.5%, twin in 2.3% and hydramnios in 4%. The method of delivery in 62.5% of the cases was cesarean section. 67.6% of preeclamptic patients had maternal and fetal complications (10.2% Maternal and 57.4% fetal). The maternal complications were: abruptio placenta, (44.4%), eclampsia (22.2%) and coma (11.1%). The fetal complications were: IUGR (42.4%), prematurity (39.6%) and IUFD (9%). Conclusion: In this study the incidence of severe preeclampsia was higher, which may be due to insufficient prenatal cares and delay in diagnosis. Further studies about the effect of prenatal cares on pregnancy outcomes in preeclamtic women are recommended.
Reza Khandagi , Mohammad Yazdchi Marandi , Mohammadali Arami , Volume 4, Issue 4 (12-2004)
Abstract
Background & Objectives: Cerebrovascular accidents (CVA) are among the most common neurologic problems affecting people of middle and old ages and are one of the causes of seizure in these age groups. Epileptic seizure in patients with stroke occurs in the forms of early and late seizures and could be seen as simple or generalized. The aim of this study was to evaluate the incidence of early seizure in patients with stroke. Methods: All 716 patients with cerebrovascular accidents admitted to Imam Khomeini Hospital during the year 2002 participated in this descriptive study. The data were collected using the patients, records. The stroke was diagnosed through clinical findings, CT Scan and MRI (if necessery). Results: Early seizures were documented in 46 (6.4%) of 716 patients, including 16 cases (5%) with atherosclerotic thrombosis, 10 (8.4%) with embolic infarction, 10 (5%) with intra cerebral hemorrhage and 10 (16.9%) with subarachnoid hemorrhage. Twenty-four (52%) out of 46 patients had Tonic- clonic seizures, 14 (30.5%) simple partial seizures, 5 (11%) complex partial seizures and 3 (6.5%) tonic-clonic status. Conclusion: It was found that incidence of early seizures in stroke is 6.4%and early seizures are more common in subarachnoid hemorrhage and embolic infarction than embolic and atherothrombotic infarction.
Naser Safaii , Nasrollah Maghami Pour , Volume 4, Issue 4 (12-2004)
Abstract
Background & Objectives:Aortic coarctation occurs in 6 to 8% of patients with congenital heart disease. It is the fourth most prevalent heart disease which requires catheterization and surgical involvement in the early years of life. If surgical repair is not conducted on-time, it can lead to heart failure (HF) and death. That is why we decided to study this disease in shahid Madani hospital, Tabriz. Methods:53 patients with aortic coarctation who underwent surgery from early 1999 to late 2003 in Tabriz Shahid Madani Research and Health center were studied retrospectively. Results: 88% of the cases were diagnosed during routine examinations. The most frequent complaints of the patients were palpitation (45%) and exertional dyspnea (41%), and the most important signs were systolic ejection murmur in 96%, weakness of lower limbs pulses in 86% and hypertension in 45%. In ECG, 96% of the patients had LVH and in CXR, 45% had cardiomegaly. In angiography, 100% of the patients had apparent aortic coarctation, which in 14 this was associated with Patent Ductus Arteriosus (PDA) In other 15 cases, PDA was not reported in angiography but was discovered during operation. The most common surgeries were resection, end-to-end anastomosis (43%) and Dacron patch angioplasty (39%). In both methods the pressure graradient decreased to under 10 mmHg in the site of anastomosis and the late complications in the patch method was more than the other one. Conclusion:The diagnosis of this disease had been delayed in these patients because of imprecise examination of all four limbs' pulses at the first examination of the patients, the patients' own ignorance, misdiagnosis, mismanagement and symptomatic therapy. In spite of PDA and low blood pressure in coarc region, these patients did not have severe pulmonary hypertension. Resection and end-to-end anastomosis is associated with less common late complications and if conducted in early ages, it can lead to complete recovery.
Nasrin Fazel , Mahin Tafazoli , Mohammad Ramezani , Habibollah Esmaili , Volume 4, Issue 4 (12-2004)
Abstract
Background & Objective: Flatulence is one of the most common postoperative disorders, which leads to abdominal distension, respiratory disorders and the openning of sutures. Some of the drugs used to alleviate the abdominal flatulence are associated with complications and harmful effects, which gives us a hint to adopt herbal medicine. The present study investigates the effect of supermint on the flatulence intensity after cesarean section. Methods: This double-blinded clinical trial study was conducted on 107 women (47 cases as placebo group and 60 cases as drug group) who had cesarean section in shahid Mobini hospital, Sabzevar. After stopping the administration of IV fluid, the subjects in both groups received 40 drops of drug and placebo every 20 minutes for 3 days. Results: The intensity of flatulence in the first 20 minutes (p=0.042), in second 20 minutes (p=0.001), in the third 20 minutes (p<0.001) and 120 minutes after intervention (p<0.001) was lower in drug group compared to before intervention. Conclusion: Supermint is effective in reducing the postoperative flatulence in cesarean section and is recommended to be used in these cases.
Reza Ghotaslou , Zyiaaddin Ghorashi , Ebadollah Heidari , Solmaz Nikvash , Volume 4, Issue 4 (12-2004)
Abstract
Background & Objectives: The conjunctiva is a mucus membrane that covers the internal surface of the eyelids and the external surface of the globe. Conjunctivitis comprises a variable group of infectious and non-infectious diseases. Bacterial conjunctivitis is a common type of ocular infections. The aim of this study was to determine the bacterial agents in conjunctivitis. Methods: This descriptive study was done on 148 patients with conjunctivitis who were hospitalized in pediatric hospital of Tabriz from March 2001 to February 2002 and had suppurative discharge. Suppurative discharge of the conjunctiva was sampled and cultured on suitable media. Antibiogram of the isolated strains was done using the disk diffusion method. The data were analyzed by SPSS software using descriptive statistics. Results : The isolated organisms were in the following frequency: Pseudomonas aeroginosa (40), Staphylococcus aureus(26), Klebsiella pneumonia(20), coagulase negative Staphylococci spp(18), Enterobacter spp(12), E.coli(10), Seratia marcescens(6), Acintobacter spp(4), Beta-hemolytic streptococcus group A(4). These bacteria had varied degrees of resistance to ciprofloxacin (37%), Chloramphenicle (52%), Gentamycin (70%) and Co-trimoxazol (71%). Conclusion: In different studies the prevalence of conjuctivitis infection is reported to be 20-40% but we found 94.5%. Regarding the importance of bacterial conjuctivitis infection in hospital and the possibility of the transmission of resistant infection to the society, some measures shoud be taken to decrease these infections.
Naser Mozaffari, Mohammadali Mohammadi, Behrouz Dadkhah , Abdollah Mahdavi , Volume 4, Issue 4 (12-2004)
Abstract
Background & Objectives: Haemodialysis has been used as a replacement therapy in patients with end- stage renal failure for several decades. But it is not clear yet how much haemodialysis a uremic patient needs? There are different methods for the assessment of needs and adequacy of dialysis. One of these methods was measurement of KT/V of haemodiolytic patients. The aim of this study was to determine dialysis adequacy of haemodialytic patients in Ardabil dialysis center . Methods: In this descriptive study, all of the hemodialytic patients (70 cases) in 2002 were studied. Urea and blood cells were determined in the patients' blood samples both before and after dialysis. KT/V methods were used to determine the adequacy of dialysis. The data were collected and analyzed by SPSS software using descriptive (mean,standard deviation) and analytical (X2) statistics. Results: The findings showed that KT/V was smaller than 1.2 in 90% of cases. 54.3% of patients were dialysed three times a week mean of dialysis duration was 2.4 ± 1.63 years. Mean of hemoglobin was 8.27 ± 1.69 gr/dl. There was no significant relationship between dialysis adeqnacy and instrument type. Conclusion: 90% of haemodialytic patients in this center did not have adaquate dialysis in terms of KT/V criteria. As a result it seems necessery to pay more attention in order to improve the present condition.
Rahim Masoumi, Volume 4, Issue 4 (12-2004)
Abstract
Background & Objectives: Congenital cataract surgery is one of the complicated and difficult surgeries in ophthalmology. Its prevalance is one per 2000 live birth but it is one the main causes of blindness in children. This prevalence is even higher in underdeveloped countries (30 in 100000 cases). Lensectomy & vitrectomy by vitrectome device are the latest methods in this regard. The objective of this study was to evaluate the post-operative results of this method of surgery in patients operated because of congenital cataract. Methods: After the diagnosis of the congenital cataract and primary examinations, the patients, in necessary cases, were examined under anesthesia and if possible, in all patients retinoscopy was conducted and intraocular presure was measured. If the examination of the retin was possible, the red reflex was determined. Then the patients were garded to D( absence of cloudy lens), 1( the presence of opacity up to 1 mm), 2A (the area of apaque part less than nonopaque area), 2B (the area of opaque part more than nonopaque area) and 3 ( complete opaqcity of lens). All of the patients were evaluated in two groups: first, only congenital cataract second cataract due to trauma. Results: In the first group (with 24 patients and 33 eyes). 26 eyes (79%) had very good postoperative condition, 4 eyes (12%) had good condition and 3 eyes (9%) were nearly good. In the second group including 17 patients, 9 eyes (56%) were very good and 4 eyes (26%) good and 4 eyes (26%) moderate in terms of postoperative results, and none of them had poor results. Conclusion: Because of the good surgical results of lensectomy and vitrectomy in congenital cataract and rapid visual acuity they are still methods of choice in congenital cataract surgery.
Simin Atash Khoii , Mehri Jafari Shobayri , Sohrab Negargar , Volume 5, Issue 1 (4-2005)
Abstract
Background and Objectives: Pre-eclampsia is one of the common causes of maternal mortality. A main problem with induction of general anesthesia in these patients is exagergted increase of blood presscure during laryngoscopy and intubation that is associateed with a significantly increased intracranial pressure with the risk of cerebral hemorrhage. There are some strategies to minimize extreme increase in blood pressure during laryngoscopy and intubation. The aim of this study was to evaluate the effect of Fentanyl-Droperidol combination (Talamonal) on reducing cardiovascular responses due to laryngoscopy and intubation in preeclamptic parturient. Methods: Thirty preeclamptic parturients who were admitted for emergency caesarean section under general anesthesia were studied. All patients had diastolic pressures sustained at ≥ 100 mmHg, and had received antihypertensive therapy. A standard general anesthesia was induced in all patients. Fentanyl-Droperidol combination was used only in the case group five minutes before induction of anesthesia. Results: Arterial pressure and heart rate increases, improved in approximately 86.6 % of the case group. The mean increase in systolic pressure, and heart rate following laryngoscopy and intubation was significantly different in two groups (P=0.0001). There was no significant difference in the mean Apgar score of the neonates at 1 and 5 minutes after delivery in two groups. Conclusion: Using Fentanyl-Droperidol Combination during induction of anesthesia produced a clinically significant decrease in sympathetic response to laryngoscopy and intubation in most mothers, without any adverse effect on the neonates.
Ahad Azami, Mohammad Ali Mohammadi , Rahim Masoomi, Volume 5, Issue 1 (4-2005)
Abstract
Background & Objectives: Narcotic abuse is one of the main problems in the world today, and individuals ’ view towards it is important for managers and social problem analysts.Regarding the threats and harms of the prevalence of narcotics in society, this research was done to determine the rate of tendency to narcotics among people over ten years old in Ardabil province. Methods: This was a descriptive cross-sectional research. A two-section questionnaire was used to collect the data. 600 men and women over ten years of age were chosen through systematic cluster sampling and the required information was gathered by referring to their houses and interviewing them. The collected data were analyzed by SPSS software using descriptive and analytical statistics. Results: 3.5% of the samples had positive family history of using narcotics. 18% were smokers. 84.7% believed that one can use narcotics everywhere. 30% claimed that using narcotics reduces one ’ s physical discomfort, and 30.2% expressed that one can give up the narcotics whenever necessary. On the whole the tendency towards addiction among the subjects was 53.57%. This tendency was higher in rural areas compared to the cities (56.72% versus 49.81%). This difference was statistically significant (p<0.001). Illiterate people had the most tendency rate towards addiction (55.61%). There was a statistically significant relationship between tendency towards addiction and positive family history (p< 0.05). The highest tendency rate (54.33%) was seen in 11- 20 age group. Conclusion: the results showed that the consequent dangers of addiction are not known for people and that the great tendency for narcotics shows the need to inform the society in order to prevent the addiction.
Farnaz Ehdaeevand , Mohammad Tagei Neeknejad, Naiere Aminisani, Mahdi Chinifroush, Volume 5, Issue 1 (4-2005)
Abstract
Background & Objectives: cervical dysplasia indicates the growth disorder of cervix and is characterized by the appearance of cancerous and precancerous cells in cervix. Cervical dysplasia often has no symptoms but can progress to cervical cancer in 5 % of the cases. Early diagnosis of these pre-invasive lesions with pap smear can prevent, to a great extent, the progress of lesion to cancer. The prevalence of cervical dysplasia is different in different parts of the world and depents, to a great extent, on its etiology. This study was an attempt to determine the prevalence and types of cervical dysplasia in 5000 cases of pap smears. Methods: This descriptive cross-sectional study was conducted on 5000 cases of pap smears selected randomly from among 8249 pap smears in the period between March 2003 to August 2004. Some samples were studied retrospectively and some others prospectively. The population of the study was composed of women referring to Ardabil health care centers for pop smear test. The data were collected with questionnaires and were analyzed using SPSS software (ver.11). Results: Cervical dysplasia was found in 56 cases (1.12%) 0.66% of which was CIN I, 0.3% CIN II and 0.16% CIN III. Conclusion: The total percentage of cervical displasia in this study was 1.12%. This prevalence in other similar studies varies between 0.4% in Scotland and 12% in USA. Nevertheless, the prevalence found in this study is in line with most of the similar researches.
Manoogehr Barak , Firooz Amani, Mehrdad Mirza Rahimi , Nateg Abbasgholizadeh, Ali Reza Hamid Kholgh , Volume 5, Issue 1 (4-2005)
Abstract
Background & Objectives: Neglecting children can have irremediable and harmful effects on them concerning their growth, evolution, acquisition, and health both at present and in the future. Since lack of nutrition knowledge and failing to observe the principles of infant nutrition is one of the important causes of malnutrition and its unpleasant consequences, we decided to carry out an assessment concerning mothers’ level of awareness about infant nutrition and the factors affecting this knowledge, as well as the effect of this knowledge on growth and development of children. Methods: This descriptive-analytical research was conducted to evaluate mothers’ knowledge of infant and neonatal nutrition and its effect on infant growth in Hir health center. The data were collected using a questionnaire, including 20 questions, which was filled out in the health center. Moreover weight, height and head circumference of 100 infants were measured. The data were analyzed using SPSS software. Results: All mothers’ age ranged between15-36 and were housewives.15% were unlettered, 18% had high school education and others primary or secondary school education. 55% of children were female and 45% male. 67% of mothers had knowledge about proper neonatal and infant nutrition. 97% of them had little knowledge about when to start introducing different nutrients for infants, 3% had moderate knowledge in this regard. Conclusion: Regarding the findings of this study and the lower knowledge level of mothers about when to start giving different food to infants as well as the importance of proper nutrition in their growth, it is necessary to improve mothers’ knowledge and promote children’s health.
Habib Ojaghi, Rahim Masoumi , Elham Ghaebi , Volume 5, Issue 2 (6-2005)
Abstract
Background & Objectives: Pterygium is a common ophthalmic disease which can cause astigmatism and restriction of visual field and cosmetic problems. Regarding the high recurrence rate using the common methods and because similar studies have never been done in Ardabil province, we decided to study the recurrence rate of pterygium after surgery with intraoperative application of mitomycin C. Methods: In this descriptive cross-sectional study all patients with primary pterygium who had undergone surgery between February 2001 and September 2003 were assessed and followed up for postoperative examinations. The findings were then statistically analysed. Results: In this study 83 eyes of 80 patients were examined. The highest prevalence of pterygium was in age group 31-40. Most of the patients had undergone unilateral surgery. In terms of size the most prevalence of pterygium was 3-4 mm. 4 cases (4.8%) had recurence one of which was observed in the first 2 months after surgery and three others in 2-6 months after it. In 50% of the recurred cases pterygium was 4 mm and in the rest of them it was 5 mm in size. After operation just 2 cases had granuloma which did not respond to topical corticosteroids and were excised by surgery. Conclusion: This study shows that the recurrence rate of pterygium after surgery with intraoperative mitomycin C is very low and this method has no serious complications. Using this method routinely is recommended. Moreover the recurrernce rate of pterygium is associated with its size.
Masuood Parish, Soosan Rassoli, Mohammad Reza Afhami, Farnaz Moslemi, Volume 5, Issue 2 (6-2005)
Abstract
Background & Objectives: Oculocardiac reflex (OCR) is presented with bradycardia and other arrhythmias, is induced by mechanical stimulation and therefore, encountered during strabismus surgery. The aim of this study is to determine the incidence and risk factors of cardiac arrhythmias during strabismus surgery in children and adults. Methods: In this prospective, randomized and double-blind study, 46 patients ASA class I and II underwent elective strabismus surgery with general anesthesia and were allocated to one of the two groups: children under 12 and adults over 12. All patients received standard general anesthesia based on their age. Demographic data, type of involved muscle, the incidence, (type and frequency) and the cause of arrhythmias and skillfulness of the surgeon (professor-assistant) were recorded. Results: There were 26 patients in children group and 20 patients in adult group. The overall incidence of arrhythmias was 91% with 96.15% in children and 85% in adults. There was not any significant difference in the incidence of arrhythmias, and the mean rate of occurence between two groups. Most of the arrhythmias were due to external ocular muscles traction. Conjunctival traction and pressure on the globe were the other causes. Stimulation of median rectus muscle as the most important arrythmogenic factor was seen in 13 children and 12 adults. Bradycardia and tachycardia were among common arrhythmias, but there was no significant difference between two groups (P>0.05) in terms of their incidence. Conclusion: This study showed that the incidence of arrhythmias during strabismus surgery is high in both children and adults. This reflex does not often lead to hemodynamic compromise, however, for its early diagnosis and treatment, close and continuous monitoring of the patient as well as cooperation and communication between anesthesiologist and surgon is needed.
Saied Javad Toutounchi, Parvane Abbaszadeh, Mahmood Barzgar , Volume 5, Issue 2 (6-2005)
Abstract
Background & Objectives: Hearing is perhaps the most important sense in human beings without which communication with the environment would greatly diminish. Chronic perforation of tympanic membrane, ossicular erosion and tympanosclerosis are major causes of hearing diorders. Nevertheless, a conducting hearing loss is the commonest complication of chronic otitis media. Cholesteatoma which is the most dangerous complication of chronic otitis media is treated by surgery. Tympanosclerosis is also one of the most important complications of chronic otitis media, which leads to conductive hearing loss through ossicular fixation. This study is an attempt to determine the effect of different kinds of chronic otitis media on the hearing of the patients. Methods: In this survey, 440 patients with chronic otitis media, who were surgically treated in the department of otolaryngology between 1998-1999, were studied in terms of various pathology of middle ear and the resultant level of hearing impairment. Results: 37 patients (8.4%) were involved bilaterally with otitis media. The number of operations on the left ear was 10% more than those on the right. The most common pathology recognized in examination was nonprulant perforation of tympanic membrane in 179 cases (40.7%) and the most common pathology recognized in surgery was cholesteatoma in 140 cases (30.2%). From 440 patients, 430 cases had conductive hearing loss and 92 cases (20.9%) had sensorineural hearing loss. Cholesteatoma of middle ear caused the highest proportion of conductive hearing loss and majority of the cases with sensorineural hearing loss (about 30%) whereas tympanosclerosis caused the most severe sensorineural hearing losses. Conclusion: The findings indicated that cholesteatoma and tympanosclerosis were the most common causes of both conductive and sensorineural hearing loss with tympanosclerosis as the cause of the most severe sensorineural hearing loss. However granulation tissue is the most common histopathology in patients with chronic otitis media at references and papers.
Mehri Jafari Shobeiri , Simin Atash Khoii , Volume 5, Issue 2 (6-2005)
Abstract
Background & Objectives: It is estimated that as many as 75% of women experience at least one episode of vulvovaginal candidiasis during the lifetime and about 5% will have recurrent infections. There are clear association between vaginal candidiasis and uncontrolled diabetes mellitus. The purpose of this study was to determine whether non-diabetic women with recurrent vaginal candidiasis have an impaired glucose metabolism. Methods: This case-control study was carried out with 32 patients suffering from recurrent vulvovaginal candidiasis as case group and 30 control patients who had negative history of vaginal candidiasis during the previous year and had referred to the clinics for reasons other than vaginal candidiasis. The case group had referrd to the gynecology clinics three times during the previous year and were recognized to have vaginal candidiasis. They were being treated by antifungal drugs and had at least one positive candida culture. Both groups underwent standardized oral glucose tolerance test with 75-gram dose of glucose. The data were analysed using Chi-square and t-test. Results: Women with recurrent vaginal candidiasis had a mean body mass index greater than the control subjects (23.4 versus 21.5, p=0.001). They had no more incidences of overt or preclinical diabetes mellitus than the control subjects, but a greater proportion of them had at least one glucose concentration above the 95th percentile (p=0.015). Glucose concentrations were significantly higher in recurrent vaginal candidiasis cases than in control subjecs at 30, 60 and 75 minutes after the intake of 75-gram dose of glucose (p<0.05). This amount of glucose led to a 15.8% increase in serum glucose level in case group compared to the control group. Conclusion: Glucose tolerance test was mildy impaired in women with recurrent vaginal candidiasis. The plasma glucose concentration increased in 2 hours after 75 g glucose intake. Although the obtained results were not in the range of occult diabetes, it can designate the important of glucose tolerance test in women with recurrent vaginal candidiasis.
Shahram Habibzadeh, Latif Gachcar, Mohammad Reza Masjedi, Ali Akbar Velayati , Volume 5, Issue 2 (6-2005)
Abstract
Background & Objectives: Some special characteristics of mycobacterium tuberculosis such as long time incubation period in culture media needed for colony appearance, unavailability of serologic methods for diagnosis, along with necessity of starting treatment in the patients with severe conditions as well as isolation limitations requires the introduction of rapid and innovative diagnostic tests. On the other hand, some diagnostic tests such as Polymerase Chain Reaction (PCR) require special experimental conditions which are not easily available to clinicians. This study was designed to determine the diagnostic value of serum adenosine deaminasae in pulmonary tuberculosis and evaluate its efficacy in pulmonary tuberculosis diagnosis. Methods:This cross-sectional study started in spring 2002. Continuous sampling was done and admitted patients were observed, examined and interviewed using a diagnotic test. All patients admitted with a suspected pulmonary tuberculosis diagnosis based on physical examination, history and chest X-Ray results were followed up for six months to ensure that mycobacterium tuberculosis infection was appropriately diagnosed. Blood samples were taken for serum ADA and complementary diagnostic tests. Following certain necessary tests and work-ups patients with or without tuberculosis were identified. Results: 131 Patients were evaluated completely. 103 had tuberculosis and 28 patients had other diseases. No statistically significant difference was found between mean level of serum ADA in two groups. But a serum level of ADA greater than 51 U/L was associated with 90% positive predictive value and specificity in differentiating two groups. Conclusion: Serum ADA is not a suitable test for pulmonary tuberculosis diagnosis.
Ahmad Rahmati, Jan Brazier, Volume 5, Issue 2 (6-2005)
Abstract
Background & Objectives: Clostridium difficile as an etiologic agent of pseudomembraneous colitis and major cause of nosocomial antibiotic-associated diarrhoea is typed by phenotypic and molecular methods. The aim of this study was to investigate the distribution of ribotypes of the organism in the given region and time. Methods: In this study 18 strains isolated from patients from different hospital wards of Poland in 2002 and 2003, were examined and identified by susceptibility to vancomycin and metronidazole. The samples were re-identified using UV and latex agglutination to ensure the existence of A and B toxins. DNA was extracted and after amplification by PCR and electrophoresis, the strains were ribotyped. Results : The findings showed that all the strains were susceptible to vancomycin and metronidazole and all the colonies showed greenish-yellow fluorescence under UV. Moreover, all the strains were positive in terms of latex agglutination. Seven strains were toxin A positive and all were toxin B positive except one strain. In molecular ribotyping it was found out that these strains belonged to seven ribotypes, namely 12, 14, 17, 18, 29, 70 and 90 most of which were ribotype 17 (61%). Conclusion: Our observations imply that in each area a particular ribotype of c.difficile is of higher prevalence and ribotyping of this clostridium is necessary for epidemiologic studies. Identification and PCR-ribotyping of common strains of this organism in Iran are recommended for epidemiologic follow-ups.
Jafari Rahimi Panahi , Ata Mahmoudpour , Sohrab Negargar, Rasool Azarfarin , Volume 5, Issue 2 (6-2005)
Abstract
Background & Objectives: One of the most common ways in intubation without muscle relaxant is using propofol and remifentanil. The common practice is injection of remifentanil and then propofol. This occasionally produces severe hemodynamic changes. The aim of this study is to inject propofol followed by remifentanil for evaluating the effect of the order of injection on decreasing these complications. Methods: 40 patients with American Society of Anesthesia (ASA) class I-II, who underwent minor elective surgery with airway mallampati class I-II entered the study. Patients were randomized into 2 groups each with 20 patients. The first group received 2.5mg/kg propofol followed by 1.5 g/mg remifentanil while the second group received 1.5 g/mg remifentanil followed by 2.5 mg/kg propofol. Laryngoscopy and hemodynamic changes were compared in two groups. Resutls: There was no difference between two groups in laryngoscopy attempts (P=0.145) but the frequency of easy laryngoscopy in the first group (85%) was more than the second group (60%) (P=0.031). Systolic blood pressure changes after laryngoscopy in the first group (20 7.7 mmHg) was less than the second group (28 6.7 mmHg) (P=0.001). There was no statistical significant difference between two groups in diastolic blood pressure and heart rate changes (P=0.88, P=0.86 respectively). Conclusion: Administrations of propofol before remifentanil during anesthesia induction produces acceptable hemodynamic changes in patients.
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