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Showing 63 results for Ast
Yusef Hamidzadeh Arbabi, Rasoul Nemati, Hamed Rezakhani,
Volume 22, Issue 2 (7-2022)
Abstract
Background & objectives: One of the main effective factors in combating gastric cancer is having good health literacy in the community. The aim of this study was to determine the health literacy of gastric cancer in clients and patients admitted to Imam Khomeini Medical Center in Ardabil.
Methods: The present study was a cross-sectional study. The sample of this study consisted of clients and patients admitted to Imam Khomeini educational -medical center in Ardabil in the second half of 2019. The sample size was 320 people which were randomly sampled. Researcher-made tools were used after ensuring validity and reliability. The questionnaire had two parts: demographic characteristics and items of health literacy dimensions. Patients' informed consent was obtained before completing the questionnaire. Data were collected by nurses and entered into SPSS-26 software. By using descriptive and analytical statistical parameters such as frequency and frequency percentage, mean and standard deviation, t-test and ANOVA analyzed.
Results: The mean and standard deviation of the age of participants was 42.98±14.35. The overall level of health literacy about stomach cancer was calculated as 31.13. The average gastric cancer health literacy in five dimensions in the clients and patients of Imam Khomeini educational-medical center in Ardabil was calculated as follows: access to health information resources was 38.02±10.6, reading health information was 13.47±4.41, understanding health information was 30.37±6.9, evaluation of health information was 16.73±4.58 and decision-making and application of health information was 58.49±10.77. Apart from reading in other dimensions of health literacy, no significant difference was found between clients and inpatients.
Conclusion: The results of this study showed that the mean score of health literacy of clients and patients admitted to Imam Khomeini medical center in Ardabil from gastric cancer is low and not sufficient. Considering the role of health literacy in energy storage, cost and time management of the individual's disease, it is necessary to plan and perform more efficient interventions to promote health literacy in the community, especially clients and patients admitted to Ardabil educational medical centers on gastric cancer.
Soheila Fakhrian Roghani, Allahyar Arabmomeni,
Volume 23, Issue 4 (1-2024)
Abstract
Background: Obesity is a major health problem worldwide. Therefore, the purpose of this study was to determine the effects of l-carnitine supplementation on physical factors related to health and lipid profiles in obese female children with basic gymnastics exercises.
Methods: In this quasi-experimental study, with a pre-test-post-test design and a placebo group, 60 obese children among the girl students of Isfahan with BMI=30.28 kg/m2 were selected purposefully and were divided into 4 groups (Basic gymnastics training, L-carnitine consumption, Combined, and Placebo). The training protocol was implemented for 12 weeks, three times a week, and 45 minutes for each session. Furthermore, the groups of L-carnitine consumption and combined used L-carnitine tablets with a dose of 2 g per day for 12 weeks. To analyze the data, multivariate covariance, and post hoc Tukey tests were used.
Results: A significant increase in Cardio-respiratory endurance, muscular endurance, muscular strength and flexibility was observed in both basic gymnastics training and combined groups (p≤0.001). In addition, a significant decrease in total cholesterol, triglyceride, and LDL and a significant increase in HDL were observed in the basic gymnastics training, and combined groups (p≤0.002). Also, the changes caused by the combined group on all variables were significantly better than other groups.
Conclusions: These findings indicate the beneficial effects of basic gymnastics training along with L-carnitine supplementation on physical factors related to health and lipid profile in obese children. Therefore, the combined use of basic gymnastic exercises and L-carnitine supplementation can be useful to improve these variables.
Homa Akhavan Aghghaleh, Najmeh Ranji, Hadi Habibollahi,
Volume 24, Issue 3 (10-2024)
Abstract
Background: Gastric cancer is a type of malignancy that affects the digestive system. Symptoms of gastric cancer are often hard to detect in the early stages, and become more noticeable only after cancer cells have grown inside the stomach wall and spread to other parts of the body. The genetic code of the cancer cells is located within the genome. Synonymous and non-synonymous mutations are two subgroups of SNP codes. The purpose of this study was to investigate the correlation between genetic variants and susceptibility to gastric cancer in Ardabil province.
Methods: The distribution of variants in the genomic DNA of 150 volunteers from the general population of Ardabil was determined using whole exome sequencing. Databases such as Iranome, Alfa, GnomAD, and 1000G were used to compare allele frequencies. After calculating the frequency of variants using standard methods, Pearson correlation was utilized to statistically analyze their correlation with age-standardized incidence rates (ASRs) for gastric cancer in related populations. A p-value below 0.05 was deemed statistically significant for all analyses. Statistical analysis was conducted using IBM SPSS Statistics version 25.
Results: Significant differences in 19 variants , including rs10061133, rs1050631, rs12220909, rs12983273, rs1695, rs2274223, rs2292832, rs2294008, rs2505901, rs2976391, rs33927012, rs3744037, rs3745469, rs4789936, rs4986790, rs4986791, rs6194, rs63750447, and rs6505162 were found between the general population of Ardabil and other populations. A statistically significant difference was observed and reported at the 0.05 and 0.01 levels in relation to the correlation between the desired variants.
Conclusion: Results suggest a correlation between gene variants in carcinogenesis, highlighting the need for functional studies on gene cooperation in gastric cancer development.
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