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Showing 167 results for No
Alireza Mohebbi Pour, Behrooz Shokuhi,
Volume 10, Issue 2 (6-2010)
Abstract
Lipoid proteinosis is a rare autosomal-recessive disturbance characterized by yellowish-white deposits on the inner surface of the lips, under surface of the tongue and uncommonly other surfaces of upper respiratory tract. Changes in larynx lead to degrees of hoarsness which usually appears within the first few weeks of life after initiation of the disease. The patient tongue is firm like as wood. In some patients deposits observed on the vocal cords, labia major, scrotum, gluteal folds and axilla. The eyelid margins contain yellowish pearly papules in about 2/3 of patients. Neurologic findings such as epilepsy are rare but pathognomonic. The gene of these disturbances is recognized on 1q21 choromosome. The patient reported here is a 13 years old girl with yellowish pearly papules on the margins of her eyelids and hoarsness. Diagnosis of lipoid proteinosis is confirmed by pathologic findings.
Abbasali Imani Foolad , Zahra Rostami , Reza Shapouri,
Volume 10, Issue 3 (9-2010)
Abstract
Background and Objectives: Detection of TEM and SHV genes in ESBL producing Pseudomonas aeruginosa and their antimicrobial resistance pattern can provide useful information about the epidemiology and risk factors of associated infections. In this study we determined the antimicrobial susceptibility pattern and prevalence of ESBLs in clinical isolates of Pseudomonas aeruginosa by phenotypic and genotypic methods. Methods: In this analytic-descriptive study, 110 Pseudomonas aeruginosa strains isolated from different clinical specimens were used. The pattern of antimicrobial resistance was determined by disk diffusion (Kirby-buer) method. The ESBL production was determined by combination disk method using disks containing ceftazidim and cefotaxim alone and in combination with Clavulanic acid. SHV and TEM types of ESBL producing genes was detected by PCR. Results: In this study Co-trimoxazole and Amoxicilin with 96.4% and 92.7% and Amikacin with 17.3% showed the highest and lowest resistance against isolates respectively. According to PCR results 37.5% and 12.5% of isolate were carried SHV and TEM genes respectively and 12.5% of isolate were carried both the SHV and TEM genes. Conclusion: According to the results most of the isolates are drug resistant and among the ESBL producing strains the frequency of SHV type is higher than TEM . The isolate ceftazidim resistance was contains SHV (37.5%) and TEM gene (12.5%), that showed SHV and TEM genes play more important role in create of ceftazidim resistance than cefotaxim resistance.
Kamaladdin Hassanzadeh , Parisa Yavari Kia , Vahid Emdady, Seyedkazem Maden ,
Volume 10, Issue 3 (9-2010)
Abstract
Background and Objectives: Three major semen parameters that involves on male infertility are sperm count, motility and morphology. In 50% of couples referring to physicians, because of infertility, male factor, solely or accompanying with female factor is responsible of infertility. Some of drugs are used to improve the semen parameters. The goal of this study was to study the effect of pentoxifylline on semen parameters (count, motility, morphology, volume of semen). Methods: Sixty one patients with impairment in semen parameters were selected and semen samples requested from each participant for analysis before treatment. Then patients were treated with pentoxifyllin, 400 mg three times a day, for three months. After that we took semen specimens again and analyzed them. Results: Mean total sperm count in case group before treatment with PF was (17 millions) and after treatment with PF reached to (21 millions). In 68.9% of patient, Sperm count increased (p<0.001) Mean motile sperm percent in case group before treatment with PF was 19.42% and After treatment with PF reached to 28.78% and 88.52% of patient this parameter increased (p<0.001). Parameter motility showed the most important after treatment. Mean normal morphology of sperm percent in case group before treatment with PF was 24%and after treatment with PF reached to 26.39% and in 32.8% of patient this parameter increased (p<0.001).Mean semen volume in this group before treament with PF was 1.95ml and after treament with PF reached to 1.93 ml. There was no significant variation in semen volume after treament with PF. (p=0.321) Conclusion: Results show that Pentoxifylline has significant efficacy for increasing sperm count, motility and morphology correction (specially for sperm motility). Considering that oral PF is safe and cheap, with easy application, we can use it for improving semen parameter’s quality before performance ART.
Abbasali Imani Foolad, Maryam Hosainzadeh, Seiyed Fazlollah Mousavi ,
Volume 11, Issue 1 (4-2011)
Abstract
Background & Objectives: Pseudomonas aeruginosa is a Gram-negative and aerobic bacterium. Exotoxin A is one of the important toxins produced by the bacterium and it is the main cause of mortality. About 90% of P. aeruginosa strains produce this toxin. Biofilm is a functional consortium of microorganisms attached to the body surfaces and bacteria are embedded in extracellular polymeric substances produced by the microorganisms. This bacterium is nontoxic in the planktonic form, but as a biofilm is highly toxic. In this study, we examined the association between the presence of exo-A gene and antibiotic resistance patterns with biofilm formation in Pseudomonas aeruginosa strains. Methods: In this study 110 strains of Pseudomonas aeruginosa isolated from various infections with defined antibiotic resistance patterns were used. The PCR method was used to detect the presence or absence of Exotoxin A gene (exo-A). Ability of biofilm formation was evaluated by spectrophotometry. Association between exo-A gene and antibiotic resistance patterns with biofilms formation was analyzed statistically by Fishers and Chi-square tests. Results: exo-A gene was detected in 93 strains (84.5%). Sixty two strains were multidrug resistant and they produced broad spectrum beta-lactamase enzyme. Results showed that, exo-A positive strains had significantly higher ability to biofilm formation in comparison with exo-A negative strains (p<0.05). Also the biofilm formation was significantly higher in multidrug resistant and ESBL producing strains (p<0.05). Conclusion: The results of this study indicate that there is a significant association between exo-A gene as well as antibiotic resistance pattern and ESBl producing with biofilm formation in Pseudomonas aeruginosa. Because of importance of biofilms in the pathogenesis of this bacterium, our study could open a new window for investigation of the molecular processes involved in the formation of biofilms.
Masoumeh Hajishafiha, Shaker Salari Lac , Minoo Khairi Tabar , Siyamak Naji, Mahzad Sadaghiani , Nahideh Asadi ,
Volume 11, Issue 1 (4-2011)
Abstract
Background & objectives : Today there is a significant progress in the treatment of female infertility but there is no main improvement for the rate of implantation and live birth. This is because of non-implantation and early abortion that lead to decrease the rate of live birth. Genital infections such as bacterial vaginosis are common cause of this problem. Distinction and treatment of bacterial vaginosis is easy and non-expensive. Treatment of bacterial vaginosis could results in improving the rate of implantation and then live birth. Methods: We considered 209 infertile women treated with ICSI (intra cytoplasmic sperm injection). This study was performed in infertility clinic of KOSAR hospital affiliated to Urmia University of Medical Sciences, Iran. Before transferring of embryo, a sample was taken from posterior culdesac secretions by sterile cotton swap and fixed it on lamella. Then bacterial vaginitis was graded by a pathologist. The relationship of bacterial vaginosis with implantation and early abortion was studied. Data were entered into SPSS software and analyzed by t-test and Chi-Square test. p<0.05 is considered statistically significant. Results: Bacterial vaginosis was significantly more frequent in patients with tubal and ovulatory disorder (p=0.013). In women undergoing ICSI, bacterial vaginosis was not associated with decreased conception rate (p=0.892) and with increased rate of early pregnancy loss (p=0.44). Conclution: Bacterial vaginosis is prevalent in women with infertility. It is also the most important cause of infertility in patients with tubal and ovulatory disorder. Bacterial vaginosis does not affect fertilization rate.
Gholamreza Sepehri , Vahid Sheibani , Yasamin Pahlavan , Mohammadreza Afarinesh Khaki , Khadijeh Esmail Pour Bezenjani, Bahareh Pahlavan ,
Volume 11, Issue 1 (4-2011)
Abstract
Background & objectives: Origanum Vulgare is an herbal plant which is widely distributed in the north and northwest parts of Iran and posses therapeutic properties. The aim of this study was to evaluate the effect of intracerebroventricular (ICV) injection of aqueous extract of Origanum Vulgare L. ssp. viride on pain threshold in male rats. Methods: In this study,28 Male Wistar rats (200-250 g) were divided randomly into 4 groups (n=7) . Rats were anaesthetized with a mixture of ketamine and xylazine and placed in stereotaxic apparatus. A guide cannula was inserted into ventricular area, according to the atlas of Paxinos and Watson. One week after surgery , three groups of rats received microinjection of Origanum extract (1, 3, 6µg/rat). Controls received the microinjection of the same volume of saline. Tail flick latency (TFL) was used to assess the nociceptive response each 15 min for 120 min, using tail flick test. The results were analyzed by repeated measurement test. One-way analysis of variance (ANOVA) was used to compare the mean values of quantitative variable among the groups. The data are expressed as mean ± SEM. p < 0.05 was considered significant. Results: Intracerebroventricular administration of the Origanum extract resulted in significant and dose-dependent increase in TFL compared to controls (p<0.05). Origanum extract at dose of 3µg/rat showed the highest analgesic response. The maximum analgesic response was observed at 60 min and 90 min post extract injection (p<0.05). Conclusion: These results suggest that the ICV injection of aqueous extract of Origanum Vulgare possesses dose- dependent antinociceptive activities in the tail flick test in rats.
Manoochehr Barak , Setareh Mamishi , Seiyed Ahmad Siadati , Peyman Salamati , Ghamartaj Khotaii, Mehrdad Mirzarahimi ,
Volume 11, Issue 2 (6-2011)
Abstract
Background & objectives: Nosocomial infections increase patient’s mortality and are considered as a health problem. The aim of this study was to assess the risk factors for nosocomial infections and antimicrobial resistance pattern of isolated bacteria in NICU and PICU, in Bahrami and Children’s Medical Center hospitals, Tehran . Methods: In a prospective cross-sectional study from October 2008 to September 2009, risk factors and etiology of nosocomial infections were evaluated in all patients who showed infectious signs upon 48h admission. Infectious agents were diagnosed by the standard microbiological tests and antibiotic sensitivity of isolates was determined using dick diffusion method. The data for location of the hospital, admission history, presence of immunodeficiency, fever and using venous and urine catheters, suction, venous injection as well as cerebral shunt and surgery have been collected by a questionnaire and analyzed, statistically . Results: About 9.3% (70 individuals) of cases encountered with nosocomial infections. From whom, 24.3% were infected by Pseudomonas aeroginosa and 18.6% and 3.14% by Klebsiella pneumonia and Enterobacter spp, respectively. The location of the hospital, using of suction and surgery were the most common risk factors related to nosocomial infections (p<0.05). Conclusion: Our findings showed that the hospital location, suction and surgery were the most common risk factors and Pseudomonas aeroginosa, Klebsiella pneumonia and Enterobacter spp were the common infectious threats. So, we need to design the special program to improve nosocomial infection control in hospitals .
Parviz Parvizi , Elnaz Alaeenovin ,
Volume 11, Issue 2 (6-2011)
Abstract
Background & Objectives: Leishmania infantum is the causative agent of visceral leishmaniasis (VL). Based on isoenzyme typing of a few isolates from patients and domestic dogs, this parasite was considered to predominate in the Kaleybar focus of VL in northwest Iran. There is no report of sandfly infections in this region so this study was aimed to investigate the infection of the sandflies in the field. Methods: Sandflies were sampled using sticky paper and CDC traps. Morphological identifications were carried out based on characters of the head and abdominal terminalia. DNA extracted from sandflies abdomens and thoraxes. ITS-rDNA gene of parasite was detected and identified as Leishmania after sequencing. Results: Out of 146 sandflies 9 were found to be infected with Leishmania. For first time, three Leishmania species (L. infantum, L. tropica and L. major) were identified in sandflies simultaneously in the region. Among the all sandflies only one Phlebotomus perfiliewi (vector of VL) was found to be infected with L. infantum. All Isolates were confirmed by sequencing of ITS-rDNA gene. Conclusion: However, Leishmania tropica and L. major were found more than L. infantum in sandflies in Kaleybar but it could not conclude that these two species of Leishmania are causative agents of VL. Because many criteria should be considered to incriminate an agent or vector of the disease.
Gholamreza Zarrini , Eiraj Rasooli, Mohsen Abazari, Younes Ghasemi,
Volume 11, Issue 4 (12-2011)
Abstract
Background & Objectives: Expansion of microbial drug resistance, have indicated to introduce new source of drugs with antimicrobial properties such as antimicrobial secondary metabolites which produced of Cyanobacteria spp. Antimicrobial activity of Cyanobacteria spp. of Urmia Lake catchment area was not already reported, therefore in this research, antibacterial and antifungal properties of cyanobacteria varieties isolated from this ecosystem and identification of the potent strains were investigated. Method: Different environmental samples screened for isolation of cyanobacterial strains. Cyanobacterial extracts were prepared by using different solvents. The effect of these extracts was evaluated by disc diffusion method and by measuring minimum inhibitory concentrations (MIC) against some gram positive and gram negative bacteria and fungi. Cyanobacteria spp. with the high antimicrobial activity was identified according to Microscopic and macroscopic characters and 16SrRNA sequences. Results: In this research, 54 cyanobacterial strains were isolated that six strains with significant antimicrobial activity identified as Gloeocapsa sp., Anabaena sp., Nodularia sp., Synechococcus sp., Leptolyngbya sp. and Chroococcus disperses. the highest antimicrobial activity achieved by the chloroform extract on gram positive bacteria and fungi. Minimum inhibitory concentration (MIC) levels for the cyanobacterial strains were ranged 20 to 80 µg/ml and Leptolyngbya sp. showed the highest effects on Candida krusei with MIC level 20 µg/ml. Conclusion: According to the results, cyanobacteria can be a source of production new antimicrobial compounds.the results showed that the filamentous cyanobacteria Anabaena sp., Nodularia sp., and Leptolyngbya sp. produce active compounds against gram positive bacteria and yeasts.
Kamal Yavari,
Volume 11, Issue 4 (12-2011)
Abstract
Background & Objectives: Antibody-based radiopharmaceutical drugs are the great current interest in imaging and radiotherapy of cancers, and provide an important tool for target-specific delivery of radionuclides to specific antigens in the diseased tissues. The monoclonal antibody avastin binds, neutralizes VEGF (Vascular endothelial growth factor) and blocks VEGF-induced angiogenesis in tumor tissues. In this study, the complex of avastin and beta particle was investigated as a first step in the production of a radiopharmaceutical drug. Methods: Antibody of avastin was prepared and purified. The antibody was conjugated with freshly prepared DOTA-NHS and then labeled with 153Sm-samarium chloride (185 MBq). The efficiency and in vitro stability of antibody labeling were determined using thin layer chromatography. The integrity of the radiolabeled antibody was checked by SDS-PAGE (Sodium Dodecyl Sulfate PolyAcrylamide Gel Electrophoresis) protocol. Biodistribution study of 153Sm-DOTA –Avastin was performed in BALB/c mice at 2, 24, 48 and 72 hours after injection. Results: The efficiency of antibody labeling was more than 98%. The in vitro stability of the labeled product in human serum after 120h was 83 ±2%. There was no fragmentation in the labeled antibody during SDS-PAGE protocol. The highest (%ID/g) was observed in the liver, lungs and kidneys. Conclusion: The monoclonal antibody avastin against angiogenesis was effectively radiolabeled with 153Sm. The Biodistribution study showed that it has a high specificity to accumulation in tissues with enriched blood vessels.
Eiraj Feyzi, Amin Bagheri , Samira Matin ,
Volume 11, Issue 4 (12-2011)
Abstract
Hydatid disease infection in humans is caused by larva of Echinococcus granulosus. Definitive hosts are carnivores such as dogs, while intermediate hosts are herbivores. Humans can also be intermediate hosts. Hydatid disease is clinically related to the presence of cysts, most frequently in the liver and the lungs and less frequently in the other organs such as kidney, spleen, brain, heart and bone. In this article, a case of splenic hydatid cyst is reported. A 50-years-old man was admitted to the clinic with a abdominal pain lasting for two weeks. Sonography and computed tomography (CT) scan revealed a splenic cyst. Cyst was removed by a surgery. The diagnosis of a hydatid cyst was confirmed by histopathology.
Mohammad Reza Nasirzadeh , Alireza Nourazar, Mir Hadi Khayat Nouri, Leila Roshangar,
Volume 12, Issue 1 (4-2012)
Abstract
Background & Objectives: Following to estrogen depletion in postmenopausal womens, its cardioprotective effect decreases. Stroke usually occurs in women during the menopause years. Estrogen hormone therapy is still controversial. Epidemiological data suggest that phytoestrogens have a preventive effect on various estrogen-related diseases/symptoms such as menopausal symptoms, cardiovascular diseases. Some studies suggest that genistein as an important component of soy have cardioprotection effects but its role on inflammation and cardiomyocte injury remained to be elucidated. So, this study was goaled to investigate the cardioprotective effect of methanolic soy extract on heart tissue injures. Method: In this study 40 female rats were randomly allocated into 4 groups: 1) Control (intact animals), 2) sham surgery (without ovarictomy), 3) ovariectomized (ovx), and 4) treatment (ovx and soy gavage) group that received 60mg/kg per day soy extract in drinking water for 28days (4 weeks). At the end of experiments, the rat heart tissue was processed histologically and the sections were stained with hematoxylin and eosin to examine under light microscope. Statistical analysis was performed using the wilcoxon test. Results: The results showed that ovariectomy significantly increased inflammation and cardiomyocte injury and soy extract significantly promoted heart tissue recovery (p<0.05). Conclosions: This study indicated that oral administration of soy extract has a positive effect on attenuation of inflammation and myocyte injury in ovariectomized rat.
Kamal Yavari , Mohammad Ghannadi,
Volume 12, Issue 2 (6-2012)
Abstract
Background & Objectives: The monoclonal antibody cetuximab binds to EGFR and thus provides an opportunity to create both imaging and therapeutic modalities that target this receptor. The potential of cetuximab as a radioimmunoconjugate was investigated and quality control tests (in vitro and in vivo) were performed as a first step in the production of a new radiopharmaceutical. Methods : Cetuximab solution was dialyzed and concentrated using an Amicon Ultra-15 filter. Purified antibody was labeled with lutetium-177 using the acyclic bifunctional chelator, DOTA-NHS, and radioimmunoconjugates were purified by PD10 columns. Radiochemical purity and stability in buffer and human blood serum were determined using thin layer chromatography. Integrity of the radiolabeled complex was checked by SDS-PAGE. Preliminary biodistribution studies in normal mice model performed to determine radioimmunoconjugates distribution up to 72h. Results: The radiochemical purity of the complex was 98±1%. The stabilities in phosphate buffer and in human blood serum at 96 hours post-preparation were 96±2 % and 78±4%, respectively. All of the samples, controls and radiolabeled antibodies, showed a similar pattern of migration in the gel electrophoresis. Biodistribution of Lu177-cetuximab was evaluated in normal mice and the highest ID/g% was observed in the blood (13.2±1.3% at 24 hours) and the liver (9.1±1.3% at 24 hours). Conclusion: Our results show that DOTA-cituximab can be labeled with 177Lu. Lu177-cetuximab has sufficient stability and retains its integrity. The new complex could be considered for further evaluation in animals and possibly in humans as a new radiopharmaceutical for use in radioimmunotherapy of cancers.
Masoumeh Foumani , Leila Asadpour, Alireza Azizi Saraji, Ali Sharifat Salmani, Mohammadreza Aghasadeghi,
Volume 12, Issue 3 (9-2012)
Abstract
Adjuvants are chemicals, microbial components, or mammalian proteins that enhance the immune response to vaccine antigens. Reducing vaccine-related adverse effects and inducing specific types of immunity has led to the development of numerous new adjuvants. Adjuvants in experimental and commercial vaccines include aluminum salts (alum), oil emulsions, saponins, immune-stimulating complexes (ISCOMs), liposomes, microparticles, nonionic block copolymers, derivatized polysaccharides, cytokines, and a wide variety of bacterial derivatives. The mechanisms of action of these diverse compounds are different. Factors influencing the selection of an adjuvant include animal species, specific pathogen, vaccine antigen, route of immunization, and type of immunity needed. In this paper we review the current adjuvant types, structure and mechanism of action and their application in the design and production of animal and human vaccines to provide a source for students and researchers in related fields .
Abbas Karimi , Morteza Jabbarpour Bonyadi, Mohsen Esmaeili, Saeid Dastgiri ,
Volume 12, Issue 3 (9-2012)
Abstract
Background and Objectives : Familial Mediterranean Fever, an autosomal recessive disorder, is the most common and well known periodical fevers syndrome. Disease is mainly prevalent among non-Ashkenazi Jews, Arabs, Turks and Armenia. According to the geographical location of North-West of Iran, neighboring with two high risk FMF population (Turkey and Armenia), the prevalence of FMF in this region of Iran is not unlikely. The aim of this study was to estimate the carriers rate of FMF common mutations in healthy control people. Results can be potentially useful to estimate prevalence of disease. Methods : Randomly 200 samples from healthy people [non-FMF] from North-West of Iran selected. After taking consent, DNA was extracted from blood samples of these groups. Then mutations were evaluated using ARMS-PCR and RFLP-PCR techniques. Results : from 400 studied alleles, 44 and 7 mutant alleles were found for E148Q and V726A respectively. For 2 other mutations, no mutant alleles were found. The total allelic frequency for these four common mutations was 0.132. The carriers rate was 23.4%. Conclusion : This study showed that E148Q has high mutation frequency relative to other mutations in North-West of Iran.
Mohammad Mosaferi-Ziaaedini, Khosro Ebrahim, Davar Amani, Zahra Arabnarmi,
Volume 12, Issue 3 (9-2012)
Abstract
Background & Objectives : Intense training increases the production of free radicals and causes inflammatory response in athletes. Strengthen and improving athlete’s immune system may reduce the harmful effects of intense physical activity. The aim of this study was to investigate supplementary consumption of coenzyme Q10 on serum concentration of tumor necrosis factor-alpha (TNF-α) during the maximal activity. Methods : Twelve healthy active males (age 21.75 ± 0.64 yr, BMI 23.7±0.94 kg/m2) performed 30-min exercise at 80% to 85% HRmax. Subjects 120 minutes pre-exercise received either of the following regimens: Coenzyme Q10 (2 mg per kg body weight) or placebo (food color). Blood samples were obtained prior to supplement consumption and immediately after exercise, then groups were reversed after 4 days. The data were analyzed using paired and independent t-test. The statistical significance was set at p<0.05. Results: TNF-α serum level increased in both supplementation and placebo group (4.2% and 5.12% respectively) and the difference between two groups was insignificant. Conclusion : The results of this study indicated that after maximal activity increasing of TNF-α serum level was slower in the supplement group in comparison with placebo group but Q10 consumption did not caused a significant difference between two group (p=0.8).
Mehrnaz Mashoufi, Robab Nazari, Roghayieh Shirinkam Chouri, Afshan Sharghi, Afrouz Mardi, Maryam Azari ,
Volume 12, Issue 3 (9-2012)
Abstract
Background & Objectives : Bacterial vaginosis is a condition which is determined by changes in microbial ecosystem of vagina and is considered as a preventable risk factor for preterm delivery. This study was conducted to assess the effectiveness of bacterial vaginosis screening program in routine prenatal care and its effect on decreasing preterm labor. Methods: This clinical trial study was conducted on 474 pregnant women at gestational stage between 2007 and 2008. The participants were randomly divided into 2 groups: intervention group and control group. Screening was performed in intervention group with Amsel's criteria (3 of 4 needed for diagnosis). Positive cases were given clindamycin cream (2%) for one week. The outcome of the delivery was assessed in both groups afterward. Data were analyzed by SPSS11 software using descriptive statistics. Results: There was no significant difference between two groups regarding pregnancy rank, wanted and unwanted pregnancy, insufficient weight gain, mother vaccination and complication of pregnancy. Bacterial vaginosis was observed in 17 out of 216 (8%) in the intervention group and then treated. Prevalence of preterm delivery in the intervention and control groups were 3 (1.4%) and 12 (4.7%), respectively. The relative risk was protective (RR: 0.3, DR: 0.033, NNT: 30). Conclusion: Screening and treatment of bacterial vaginosis in pregnant women could significantly decrease the rate of preterm delivery.
Mohsen Mardani-Kivi, Ali Narvani, Morteza Nakhaei-Amroodi, Keyvan Hashemi-Motlagh, Khashayar Saheb-Ekhteiari,
Volume 12, Issue 4 (12-2012)
Abstract
Background & Objectives: Over 150 different surgical techniques for treatment of anterior shoulder instability has been suggested that there is no consensus in the orthopedics. This study seeks to compare treatment outcomes of arthroscopic Bankart lesion repair methods with Bristow - Latarjet open surgical technique in patients with anterior shoulder instability. Methods: In this cross-sectional study all patients with recurrent shoulder dislocation from 2009-2011 was divided into two groups, arthroscopic Bankart treatment (28 cases) and open Bristow - Latarjet (26 cases) that all were treated by one orthopedic surgeon. Patients were visited in 2,4,6,8 weeks also in the third and sixth month post-op .The visual analog scale (VAS) for patient satisfaction and Walsch-duplay and Rowe score for functional outcomes of treatment were used in six months follow up. These three criteria were analyzed again after recalling the patients. Results: Mean age of 54 patients was 29.46±9.16 years and mean follow-up duration was 23.28 ± 6.2 months. Scores of patients in both groups were not statistically different after analyzing the functional outcomes of treatment by Walsch-duplay and Rowe score after six months and final follow-up. Scores of patients by Walsch-duplay measurement in arthroscopic Bankart and Bristow-Latarjet groups were 98.03±4.37 and 97.88±4.51 respectively and by Rowe index were 97.32±5.52 vs. 97.88±4.51at final follow-up. No recurrence was observed in both groups in final follow up. Patient satisfaction in Bankart and operation groups were 9.4 ±0.68 and 9.47±0.58 (p= 0.69). Conclusion: In anterior shoulder instability, minimally invasive Arthroscopic Bankart procedures almost equal to open Bristow-Latarjet method with regards to shoulder stability, recurrence rate, and range of motion.
Hadi Sadeghi, Pari Bagheri Ardebilian, Mehdi Fazlzadeh Davil, Roohollah Rostami, Yousef Poureshgh,
Volume 12, Issue 4 (12-2012)
Abstract
Background & Objectives: Considering the effect of Pseudomonas aeroginosa on public health as one of the most important microorganisms in swimming pools, this study was conducted to assess the possibility of contamination of hot spring pools with this organism in Ardabil province. Methods: In this study, 195 specimens were investigated from all public hot spring pools of Ardabil province during April to September 2011 when the number of swimmers reaches its peak. Standard method was used to investigate the presence or absence of P. aeroginosa in the valume of 100 ml collected samples. Results: The rates of contamination with P. aeruginosa at different months were as follows: April 17.5%, May 22.5%, June 22.5%, July 25% and August 20%. There was no statistically significant difference for P. aeroginosa contamination within the months. However, a statistically significant difference was considered for P. aeroginosa among all locations (p<0.05). Conclusion: Totally, 22.9% of specimens revealed P. aeroginosa which is alarming. So, it is suggested that monitoring and disinfection the public hot spring pools should be considered more seriously. It is also necessary to limit the number swimmers in public hot spring pools to reduce burden of contamination.
Manoochehr Barak , Farhad Pourfarzi , Shima Jirodi , Gity Rahimi , Yasamin Pahlavan ,
Volume 12, Issue 5 (11-2012)
Abstract
Background & Objectives: Nosocomial infections occur following admission of patients in the hospitals and usually are accompanied by significant mortalities. This study was conducted to determine the frequency of nosocomial infections and the causatives in Ardabil Bu Ali hospital during 2010. Methods: This study was a cross-sectional study which has been done on collection of information through practical examinations, laboratory tests and files of nosocomillay infected patients in Ardabil Bu Ali hospital during 2010. Data were analyzed by SPSS. Results: From a total of 3254 patients, 42 (1.3%) had got nosocomial infections. Of these infected patients 47.6% was males and 52.4% was females. Infection was more frequent in patients with ages between 1 month to1 year old (45.2%). Sepsis (33.3%), pneumonia and blood stream infections (23.8%) and urinary tract infection (19%) were the most frequent infections. The mean length of hospital stay was 26.86 days. Klebsiella pneumoniae was the most common pathogen reported (23.8%). Infection was more common in NICU (38.1%). Conclusion: In this study, the frequency of nosocomial infection was lower than other studies. Distribution of infection differed with age, ward and length of stay in the hospital.
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