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Showing 45 results for Cat
Gholamreza Sharifirad , Aziz Kamran , Mohammadhasan Entezari ,
Volume 7, Issue 4 (12-2007)
Abstract
Background & Objective: Diabetes is one of diseases in which the main part of treatment depends on the patient's responsibility. Therefore their knowledge of the various aspects of nutrition has great importance. The aim of this study was to evaluate the effect of diabetic diet education on nutritional behaviors. FBS and BMI of patients with type II Diabetes mellitus in Iranian Diabetic Association. Methods: 88 type II diabetic patients from Iranian Diabets Association (Karaj Branch) participated in this study. The Patients were randomly divided into two groups as experimental (44) and control group (44). Data were collected with a valid and reliable questionnaire (58questions) and checklist in two stage of before and one month after intervention. Results: After the intervention in the experimental group regarding diabetes and nutritional behaviors, there was a significant increase in mean score of knowledge (from 57.50 to 80.18) and a significant decrease in the mean of BMI (from 28.3 to 27.9) and in the mean of fasting blood sugar (from 167.9 to 134.5) (p<0.001). However, there was no significant change in the control group. Conclusion: The finding of this study indicated the efficacy of education on FBS and BMI in patients with type II diabetes.
Saeid Sadeghie Ahari , Solmaz Arshi , Manoochehr Iranparvar , Firouz Amani, Hosein Siahpoosh,
Volume 8, Issue 4 (12-2008)
Abstract
Background & Objectives: The prevalence of diabetes and its different methods of treatment have significantly been increased in the last two decades. The actual effect of these treatments is a common topic in the patients’ health and quality of life among these patients has a considerable importance in the community medicine. This study was designed to indicate the quality of life in the diabetic type II patients. Methods: This was a cross-sectional, descriptive analytic study in 2004 on 110 type 2 diabetic patients who had referred to Bu Ali Hospital in Ardabil. The patients were randomly selected and took the SF-36 Questionnaire and in the end the data were analyzed by SPSS. Results: The average age of the patients was 52.5 with the standard deviation of 11.3 years. 73 of the patients were female (66.4%) and rest of them were male. The average period of sickness among diabetics was 8 years from the time of diagnosis with a standard deviation of 6.2 years. The average of duration of therapy was 7.7 years with 6.1 years standard deviation. 51 patients (46.36%) had the history of hospitalization. Vitality indicator was low in 39.1% of patients. Social functioning was low in 50% of patients. In general, by adding up the quality of life’s various indexes scores based on SF-36 questionnaires standard coefficients, 77% of patients had intermediate and low quality of life. Conclusion: According to this study most of the patients in this study had a low quality of life.
Ali Mohammadian, Mojgan Khanbabazadeh,
Volume 9, Issue 1 (4-2009)
Abstract
Background and objectives: Every organization which is a provider of service or a product is always responsible for seeking clients, comments as feedbacks so to identify the shortcomings and on the basis of their comments, plans can go through the growth and improvement. The present study, from the view of client tendency, is aimed at measuring the rate of Ardabil University of Medical sciences students’ satisfaction with the practices of faculties, educational management, student-cultural management and the counseling unit. Methods: In this descriptive study, 705 students from all faculties were questioned. The main instrument for data collection was a questionnaire in which, in order to assure the adequacy of the concept in, measurement, content validity was used and it was applied according to the comments of some instructors. To confirm the reliability of the questionnaire, 10 subjects were chosen and the questionnaires were distributed and then collected. After 15 days of interval from the first administration, the readministration on the same group was done and the reliability of the test became 0.86 using Alpha cronbach. The data in the first stage were investigated through descriptive statistical methods SPSS 13 and in the next stage in order to determine the difference between group comments, the independent T-Test and ANOVA were used. Results: None of the units of the university got scores above average and the two units of education in the faculties and education management got an average score from student satisfaction and the mean of other units was below average. Native students of the university were more satisfied with the faculties and educational management whereas the mean of nonnative students, satisfaction was higher in student-cultural management and the counseling center. Conclusion: Student dissatisfaction with the func? of student-cultural management and the counseling unit is a shortcoming which requires the people in charge to take necessary measures to improve the quality of affairs.
Firouz Amani , Anooshirvan Kazemnejad, Reza Habibi,
Volume 9, Issue 3 (9-2009)
Abstract
Background & Objective: Mortality statistics and cause of death are the main components in health planning in any community. Knowry the change of marraliy pattern is important for future health programming. This study have to determine and analyze the Mortality changing trends dury lest 35 years. Methods: In this study data recorded of 9740556 deaths from were analyzed. Graphical method were usead to analyze dara and . We analyzed data by croghal method and comping the trouds of morality cheye pattern. Results: Our servey should 60.4% of total deaths were in rural areas and 61.1% among males. The crude death rate was 13per 1000 pasim from to 1971-76 that decrease to 5 per 1000 pasim from to 2006-2010. Also life expectancy rate has been increased in study years from 55.2 in 1971-76 to 71 in 206-2010. Conclusion: results show that mortality pattern in years 1970 to 2007 have been changed and crude death rate with decrease tread and life expectancy with increase trend represent the level of health indicators in world and our country Iran have been developed and extended.
Hormoz Azimi, Sholeh Khademabbasi,
Volume 11, Issue 3 (9-2011)
Abstract
Background & Objectives: The first Laparoscopic Cholecystectomy surgery was performed by Erich Muhe in 1985.Nowadays in developed countries, more than 90% of cholecystectomy surgeries are done by Laparoscopic method and it is one of the most common elective surgeries. The aim of this study is to evaluate the frequency and side effects of this method and the rate of conversion to open surgery patients undergoing laparoscopic cholecystectomy surgery in Sabalan and Arta hospitals in Ardabil province. Methods: This descriptive analytical study was performed between October 2006 and January 2009. We have studied 200 patients (24 male, 176 female) with cholecystitis (symptomatic gallstones) treated by Laparoscopic Cholecystectomy surgery. Data were collected through questionnaires and telephone calls (at least 6 months after surgery). Data analysis was done by SPSS statistical software and chi-square test. p<0.05 was considered as significant. Results: The average age of patients was 44.6 years. In the final diagnosis, 168 patients (84%) had chronic cholecystitis and 32 patients (16%) had acute cholecystitis. The rate of conversion to open surgery was 8 patients (4%). Eight cases (4%) were suffered organic side effects including: four cases (2%) jaundice after surgery, 1 case (0.5%) postoperative fever, 1 case (0.5%) leakage of bile, 1 case (0.5%) slight leaking of serum from the surgical site and 1 case (0.5%) associated with increased liver enzymes that had no other symptoms. About the risk factors for conversion to open surgery, there was significant correlation between acute cholecystitis and male gender. Information about the satisfaction of patients after surgery showed that, 89.5% were completely satisfied, 2.5% were completely dissatisfied and 8% were relatively dissatisfied. No deaths were seen. Conclusion: Laparoscopic Cholecystectomy is a standard selective treatment method for gallbladder stones. It has many advantages including reduced duration of hospitalization, less pain, reduced morbidity and less side effects than open surgery, lower recovery period and faster return to normal life.
Babak Nakhostin-Roohi, Nasrin Vaezi ,
Volume 11, Issue 3 (9-2011)
Abstract
Background & Objectives: Effects of new educational programs on health and physical fitness promotion is an important issue which needs regular evaluations. Physical fitness has many advantages such as cardio-respiratory health promotion, prevention of some diseases and improvement of quality of life. On the other hand, it has been shown that there is significant relationship between waterpipe smoking and cancer, cardiovascular as well as pulmonary diseases. The aim of this study was to evaluate the relationship between addiction to waterpipe smoking and cardio-respiratory fitness and body composition of physical education students in Islamic Azad University, Ardabil Branch. Methods: One hundred and eighty-one physical education students participated in this study. All subjects were selected by cluster sampling method. Cardio-Respiratory fitness (using Cooper test), Body Mass Index (BMI), Fat percent (using 2-point Lohman equation), addiction to waterpipe smoking, smoke exposure and awareness of waterpipe effects on athletic performance (using questionnaire) were evaluated. Results: The body composition of the most students was not suitable (50.3% extra fat), but the cardio-respiratory fitness of male students was better than that of female students. Furthermore, In spite of decrease in waterpipe smoking in comparison to last year (13.3% versus 35.6%), many non-smoking students are exposed to waterpipe smoke (21.0%) and some of them (48.1%) had little information about the harmful effects of waterpipe smoking on athletic performance. Conclusion: According to results of this study improvement in cardio-respiratory fitness and body composition of physical education students and enhancement of their information about side-effects of waterpipe smoking should be emphasized
Mehrdad Mirzarahimi, Adel Ahadi , Afsaneh Enteshari Mogaddam, Manoochehr Barak,
Volume 11, Issue 3 (9-2011)
Abstract
Protein C is a vitamin K dependent glycoprotein. Protein C deficiency is a rare genetic disorder and its major sites of involvement are skin, eyes, lungs, central nervous system, and kidneys. This article presents a case of neonatal protein C deficiency with severe purpura fulminans and bilateral cataracts. He was initially treated with fresh-frozen plasma and then followed by warfarin. All necrotic skin lesions improved with treatment. He was the first child of his parents who were asymptomatic for protein C deficiency. We also reviewed literatures about coexistence of cataracts and protein C deficiency.
Rezvan Zabihollahi , Maryam Nourmohammadi , Azar Farhang Esfahani, Rohollah Vahabpour, Seiyed Mahdi Sadat , Mohammad Reza Aghasadeghi , Mansour Salehi , Seiyed Davar Siadat ,
Volume 12, Issue 1 (4-2012)
Abstract
Background & Objectives : Several studies have been conducted to explore anti-HIV drugs. Discovery and study of novel anti-HIV-1 compounds need live viruses and has serious biosafety concerns. In this research we reported a novel and safe system for assaying the cytopathic effects of HIV by using single cycle replicable (SCR) HIV-1 virions. Methods: To produce the SCR HIV-1 virions, pMD2G, pmzNL4-3 and pSPAX2 plasmids were co-transfected into HEK293T cells. Different amount of SCR virions were used to infect target cells (MT-2). Within the infected cells, the number of formed syncytia was counted under the light microscopy. The lethal effects of the SCR HIV virions were measured using XTT proliferation assay. Results: Formation of syncytia among SCR HIV infected cells was detectable 24 hours after infection. Highest amount of syncytia was seen 72 hours after infection. Increase in the amount of virions caused increasing of syncytia and the cytopathic effects of SCR HIV-1. Infection with more than 1600ng P24 SCR HIV decreased the syncytium formation and viability of all cells. The calculated IC50 (50 percent inhibitory capacity) for nevirapine and BMS806 using this method was 50nM and 30nM, respectively. Conclusion: SCR HIV-1 virions are replicable only for one cycle. Using these virions can improve the safety of HIV researches. Herein, we optimized the assaying of HIV induced cytopathic effects by using SCR HIV-1 (NL4-3) virions. The accuracy of this method was accepted by quantifying the anti-HIV-1 effects of nevirapine and BMS806 by (SCR) HIV-1 virions.
Rahim Masumi, Amin Masumiganjgah , Habib Ojaghi, Eisa Banazadeh,
Volume 12, Issue 2 (6-2012)
Abstract
Background & Objectives: Visual impairment included mild visual loss to total blindness that depends on the definitions different results achieved in various studies in all over the world. These kinds of studies will be helpful for social and health problems because some of the causes of blindness are preventable and curable at early stages. Methods: This study is a cross-sectional study. In this study, 300 patients older than 40 years with CF visual acuity or less had been surveyed, and information related to the patients recorded in questionnaires. The patients diagnosed by expert physician and recorded data were analyzedby descriptive statistical methods. Results: 57% of patients were male and 43% were female, and 41% were urban and 59% rural. The most common cause of visual impairment regarding to the definitions in this study was cataract (57%) and primary glaucoma (16%), uveitis (61%), corneal disease (6%), ARMD (4.33%), diabetic retinopathy (4%) and refraction disorder (myopia) were respectively after cataract and central retinal artery obstruction with 0.66% had the less prevalence. At all, retinal disease with 15% of prevalence was in third place of the major causes of visual impairment. Cataract was the cause of 43.9% of visual impairment in men and 74.4% in women. Glaucoma (24.6%) was the second cause in men and third common cause of visual impairment in women with 4.7% and comparing with men has lower prevalence. Conclussion: In this study cataract and glaucoma were the main causes of visual impairment, same as global studies, respectively. In this study prevalence of glaucoma in men was more than the prevalence in women and appears to be related to the fact that women are more sensitive to their health status comparing with men and they go to ophthalmologists sooner than men. With knowing that glaucoma will be controllable with appropriate treatments at the early stage and irreversible visual loss will be prevented.
Ali Pezeshki, Mostafa Rezaeian , Mitra Zarebavani,
Volume 13, Issue 2 (7-2013)
Abstract
Background & Objectives: Giardia duodenalis is the most common intestinal parasite with cosmopolitan distribution. This parasite has been found in the intestine of humans and other mammalian hosts including cats, dogs, cattle, sheep, deer, pigs and muskrats. It is postulated that animals maybe reservoir for human infection and viceversa. In present study, the possible genetic similarity between cat and humans Giardia and its probable zoonosis were investigated. Methods: Direct examination and formalin-ether concentration techniques were performed on stray and semi stray cat fecal specimens. Gradient sucrose method was applied for collection and purification of cysts and DNA extraction was performed by phenol-chloroform and CTAB (Cetyl trimethyl ammonium bromid ( methods. DNA of cysts could hardly be extracted after repeated freezing and thawing. Polymerase chain reaction (PCR) was performed for DNA amplification. In this study triosephosphate isomerase (tpi) gene was selected as a molecular marker. Two sets of primers (PM 290 and PM 924) were considered. Two restriction enzymes RsaI and AvaI were also used to determine restriction fragment length polymorphism (RFLP) for PCR fragments amplified by both primer sets. Results: Ten samples were positive for Giardia cysts which were examined for molecular investigation. Four cat isolates were amplified by PM 290. PCR-RFLP patterns were found to be similar to human isolates AC≠AF 069556 (subgroup of AC≠U 57897) with possibility of cross-transmission. Conclusion: Therefore the similarity of genomic characters of isolates of cat and human Giardia implies possibility of zoonosis and transmission of these protozoa from cat to human and vice versa.
Hosein Douste Kami , Adalat Hosseinian , Effat Mazaheri, Naser Aslanabadi , Samad Ghaffari , Bahram Sohrabi , Eiraj Mohammadzadeh , Farhad Pourfarzi , Naser Moaiiednia ,
Volume 13, Issue 3 (10-2013)
Abstract
Background & Objectives: Coronary bifurcation lesions are important, complex lesions with different therapeutic strategies. In this study, patients with Coronary bifurcation lesions were treated and clinical results in these patients were followed during the nine-month period. Methods: This descriptive analytical study was performed between January 2007 to December 2008 at Tabriz Shahid Madani Cardiovascular Center. We have studied 96 patients (83 male and 13 female). Patients on the basis of one or two stents were placed in one group and the other groups were divided based on the use of Drug Eluting Stent and Bare Metal Stent. After diagnostic angiography if coronary bifurcation lesions were present based on Medina classification, appropriate angioplasty treatment was carried out. In a situations including chest pain, electrocardiographic changes or the objective evidence of ischemia and indication of angiography, appropriate diagnostic tests during follow up period were done. Clinical outcomes including acute coronary events were recorded. And result analyzed using SPSS version 16 . Chi-square ، Fisher and T tests were used to compare the relationship between variables. Results: In this study 86.5% was male and 13.5% female. The mean age of these patients was 56±9.9 years old. The most prevalent risk factor was HTN with 41.7% incidence and 55.2% of patient had chronic stable angina and 26% of them had history of acute myocardial infarction, 7.2% with history of PCI and 5.2% with history Of CABGS. Most prevalent site of bifurcation was ALD/diagonal with 65.5% incidence. The most prevalent complication was mild bleeding from puncture site with 10.4% and 5.2% of patients had mild hematoma. Among patients with two stents versus one stent presence of AMI presentation with CSA, ST Elevation in ECG was statistically significant. Also involvement of SB (side branch) lesions lengths at SB, kissing ballooning after implantation of two stents were statistically significant. Among patients with DES versus BMS usage of stent in RCA, LAD, lesion lengths at PMB (proximal main branch), DMP (distal main branch) and SB, procedure time, radiation dose, fluoroscopy time were statistically significant. Among two groups MACE (major acute coronary event) in two stents patient between 1-3 month and total MACE at first 6 month were statistically significant Conclusion: The age of patients treated with CBL was low, also more usage of BMS and stenting of BFLs with two BMS had weak results in this study but surprisingly total results of BMS and DES did not have significant difference after 9 months follow up between two groups.
Naser Parizad , Masumeh Hemmati Maslakpak , Hamid Reza Khalkhali ,
Volume 14, Issue 1 (4-2014)
Abstract
Background and Objectives: Patient education has an important role in controlling the diabetes. Tele-education is impressive due to the elimination of both space and time limitation and establishing an effective relationship with client care. This study was carried out to determine the impact of tele-education by telephone and short message service on laboratory parameters in patient with type 2 diabetes. Methods: This experimental study carried out on patients with type 2 diabetes members of Urmia Diabetes Association . A total of 66 samples selected and allocated randomly in two intervention and control groups. Data gathered with demographic questionnaire and lab work. For intervention group education and telephone follow up had given for 12 weeks. Data were analyzed using descriptive and inferential statistical testes. Results: Finding of the study showed decrease in fasting blood sugar (-29.82), glycosylated hemoglobin (-0.54), cholesterol (-13.88), triglyceride (33.88) and insulin level (-4.59) in intervention group after performance of education and telephone follow up. Conclusion: Telephone follow up and tele-education have a beneficial effect on controlling the laboratory parameters in patients with type 2 diabetes .
Adalat Hosseinian , Vahideh Kasayi , Alireza Mohammadzade , Shahram Habibzadeh , Fariba Saghi , Mahnaz Davari , Azam Barzegar, Mehri Seyedjavadi ,
Volume 14, Issue 1 (4-2014)
Abstract
Background & Objectives : Nowadays, coronary artery disease is the most common cause of death in developed countries and in the whole world. According to the WHO reports, it will be the main cause of death in 2020. Myocardial infarction is the most common diagnosis among hospitalized patients in industrialized countries. This disease causes more mortality and morbidity than others. Coronary artery bypass grafting surgery (CABGS) is one of the common treatments for ischemic heart disease but it may have some complications. In this study we wanted to evaluate the incidence of CABGS complications in Imam Khomeini Hospital of Ardabil in the first month after CABG. Methods: This study was a cross sectional analytic descriptive type and performed on all of the patients underwent CABGS in Imam Khomeini Hospital during 2011-2012. All of the data from patients (like demographic, past medical history, physical exam findings, paraclinical findings and CABGS complications) were inserted in special forms after gathering, and analyzed by SPSS v.16. Results: In this study, 211 patients were studied. About 145 (68.72%) of them were male and 66 (31.28%) were female. Seventy patient (33.17%) were more than 70 years old. About 33.22% of patients had a history of cigarette smoking and 9.95% were opioid abused. The 34.12% of patients had hypertension (HTN) history, 40.28% diabetes mellitus (DM), 17.06% history of hyperlipidemia and 63.98% had a history of the previous MI. Chest pain was the most common complication among the patients (93.36%). According to our study the prevalence rate of post CABGS complications were: bleeding after surgery 13.27%, postoperative myocardial infection 8.05%, neurological disorders 12.32%, renal complications 2.36%, respiratory symptoms 11.37% and 34.59% for cardiovascular complications. Also the total mortality was 5 (2.36%) persons. The data analysis showed that there was a significant relationship between sex with survival status, local infection and neurological disorders, and also there was a significant relationship between age with post CABGS survival, bleeding after surgery and renal complications. There was also a significant relationship between DM and post CABGS survival, local infections and respiratory complications and between HTN and local infections. Conclusion: According to the results of this study, the most common post CABGS complications were cardiovascular complications, especially arrhythmias.
Fereshteh Sharifi Ferdoey , Shiva Irani, Mojghan Zandi, Masoud Soleimani,
Volume 14, Issue 3 (10-2014)
Abstract
Background & objectives : T he main goal of tissue engineering is regeneration and restoration of damaged tissues and organs, besides being used in medicine . Scaffolds are the main segments for tissue engineering, and plasma surface modification is one of the modern methods used for surface modification on polymer scaffolds. The aim of this study was to evaluate the effect of nano-fibers with different densities on fibroblasts' behavior besides the plasma surface modification. Methods : Poly Ɛ-Caprolactone nano-fibers (PCL) were developed by an electro-spinning technique at different collecting times. These nano-fibers were then modified by oxygen plasma. Cellular attachment to the nano-fiber and their morphology were evaluated using scanning electron microscope (SEM) and cellular activities were also studied by 3-[4,5-dimethylthiazol- 2-yl]-2,5 diphenyltetrazolium bromide (MTT). Scaffold biocompatibility test was assessed using inverted microscope. Results : Scanning electron microscope images of nano-fibers showed that increase in time of spinning has significantly heighten fiber density, on the other hand plasma surface modification of nano-fibers had significant effects on their respective biocompatibilities. The result of cell culture showed that nano-fiber could support the cellular growth and replication by developing 3-dimensional topography. Conclusion : Our results showed that increase in time of spinning and using plasma surface modification of nano-fibers by oxygen plasma would result in providing surface with the highest similarity to the extracellular matrix.
M Parsian, K Hashemian, Kh Abolmaali, M Mirhashemi ,
Volume 15, Issue 2 (7-2015)
Abstract
Background & objectives: Substance abuse is one of the worst humanitarian issues in recent years which undermines the base and foundations of human society. Its prevention requires the application of multiple theories in various disciplines together with diverse methods and techniques. Several studies have been emphasized on the role of personal and familial variables as risk factors for substance use . However, this study was done in order to predict drug addiction attitude in adolescents according to the family training risk factors to prevent substance abuse and to design a model for the prevention of addiction .
Methods: This study is a descriptive and survey research performed on a sample of 373 male and female students selected randomly among the five high school students in Ghaemshahr city. Then a questionnaire including parenting styles, attitude to addiction and social problem solving skill as well as a socioeconomic questionnaire distributed among the students. For data analysis, the statistical method of descriptive statistics and path analysis has been used.
Results: Results of this study have shown that the component of parenting styles has a direct and positive impact on attitudes to drug addiction. In addition, there was a direct and positive non-significant relationship between the adaptive social problem solving skills and attitude to drug addiction and also direct and negative significant relationship between the non-adaptive social problem solving skills on this attitudes. A direct and negative significant relationship was also seen between parenting styles and attitude to drug addiction.
Conclusions: Based on the results of present study, the components of parenting styles have a direct and negative impact on attitudes to drug addiction. Also there is a direct and significant relationship between the components of non-adaptive social problem solving skills and the variable of social attitude in adolescents . But the component of adaptive social problem solving skill has a direct and non-significant impact.
Mehraban Shahmari, Seemin Dashti, Saeedeh Ameli , Somayeh Khalilzadeh, Adalat Hosseinian,
Volume 16, Issue 3 (10-2016)
Abstract
Background & objectives: Most of coronary angiography patients have not enough information about undergoing procedure . This lack of knowledge makes anxiety in patients and thereby changes their vital signs. There is no study regarding the effective education of patients based on their native language. This study was done to investigate the effect of video education in native language on vital signs caused by anxiety of patients undergoing coronary angiography.
Methods: This quasi experimental study was done in 2013 on 160 patients undergoing angiography in Imam Khomeini Hospital in Ardabil. Participants were divided into two groups randomly (80 in each group): case (native video education) and control groups. The sheets of hemodynamic variables were completed in determined time intervals for data collection. ANOVA with repeated measures and Chi square were used to analyze the data in SPSS13 software. P-value<0.05 was considered statistically significant.
Results: The results of repeated measures ANOVA showed significant improvement in vital sign variables except for temperature in both groups over the time (p<0.05). And there was significant difference in the mean vital sign variables in determined time intervals (p<0.05).
Conclusion: Video education in native language decreases the vital signs in coronary angiography patients. Therefore the video education especially in native language is recommended for improving vital signs before invasive procedures.
Iraj Faizi, Saeid Smaeilpour, Ali Nemati , Khatere Isazadeh, Farideh Faizi, Vahid Montazeri,
Volume 17, Issue 3 (10-2017)
Abstract
Background & objectives: The use of supplements such as L-carnitine, optimum nutritional support and early feeding after surgery in cancer patients can be important in the prevention of cancer complications. The aim of this study was to determine the effects of early L-carnitine-rich feeding on complications of esophageal cancer surgery and duration of hospitalization.
Methods: In a clinical trial, 50 patients with esophageal cancer under surgery in two equal groups were randomly selected. Nutritional information was obtained using food record questionnaire. Basic blood samples and 24-hour urine samples were taken in order to measure the hematological parameters (like blood cell count, hemoglobin, hematocrit and blood urea) and nitrogen balance, respectively from two groups at the beginning and end of the study. Then, the intervention group received 3 g L-carnitine daily in 3 doses on the first day after the complementary operation, with a routine hospital diet at each meal, and the control group received a routine hospital diet for ten days. Data were analyzed using independent t-test, paired t-test and chi-square test.
Results: The results showed that changes in the mean BUN and nitrogen balance were significantly different after intervention between the study groups (p<0.05). Patients with early L-carnitine-rich feeding had less hospitalization time in hospital wards and were discharged earlier (p<0.05).
Conclusion: The results of this study showed that early L-carnitine-rich feeding after surgery has probably a positive effect on the duration of hospital stay in patients with esophageal cancer.
Farid Manafi , Reza Alipanah-Moghadam , Ali Nemati, Vadood Malekzadeh, ,
Volume 17, Issue 4 (1-2017)
Abstract
Background & objectives: Andrographolide has potent antioxidant properties. There is still not a complete understanding of the antioxidant effects of andrographolide. In this study, the effect of andrographolide on the serum antioxidant activity of superoxide dismutase and catalase was investigated in the rats with secondary iron overload.
Methods: In this experimental study, 32 rats were divided into 4 groups of 8 each. The groups included: 1-Control 2- Receiving iron 3- Receiving iron treated with 7 mg/kg andrographolide 4- Receiving 7 mg/kg andrographolide. The serum activity of superoxide dismutase and catalase and serum level of malondialdehyde (MDA) was measured using colorimetric method. Prussian blue was used to evaluate iron deposition in liver.
Results: The results showed that iron was deposited in the liver. The activity of superoxide dismutase and catalase in the secondary iron receiving group, compared to control group, was significantly increased (p<0.05). The activity of catalase was significantly decreased in the group receiving iron and treated with andrographolide, compared to the control and iron receiving groups (p<0.05). Also, the activity of superoxide dismutase in the group receiving iron and treated with andrographolide decreased significantly compared to the iron receiving group (p<0.05). Serum levels of malondialdehyde in the iron receiving group were higher than the control group (p<0.05). Serum levels of malondialdehyde in the group receiving iron and treated with andrographolide, compared with the iron receiving group, showed a significant decrease (p<0.05).
Conclusion: Andrographolide (7mg/kg) reduced the serum activity of catalase and superoxide dismutase and malondialdehyde serum levels in rats with secondary iron overload.
Abbas Fadaii, Ali Majidpour, Soleymanzadeh Moghadam , Hamideh Rahmani Seraji ,
Volume 18, Issue 4 (1-2018)
Abstract
Background & objectives: Asthma is one of the most common chronic diseases in the world and Iran. Despite appropriate treatment, recent researches indicate that asthmatic patients have poor asthma control. The aim of this study was to determine the correlation between educational level of asthmatic patients and asthma control indices.
Methods: This retrospective cross-sectional study was performed on 80 asthmatic patients admitted to Shahid Labbafinejad hospital. ESMAA questionnaire was used to collect data to assess the level of asthma control, according to ACT (Asthma Control Test) and 2016 GINA (the Global Initiative for Asthma) guidelines. Patient medication compliance was evaluated based on Morisky medication adherence scale (MMAS). ANOVA test (Regression and Pearson correlation) and Chi-Square test were used for analysis of quantitative and qualitative variables, respectively. The P - value less than 0.05 was considered statistically significant.
Results: Eighty asthmatic patients with an average age of 54.65 were entered to this study that of them 32 patients were at primary school level, 26 patients at high school level and 22 patients at university state. According to ACT test, 52.5% and 47.5% of patients were in control and uncontrolled state, respectively.
According to GINA classification, 30% of patients were in control, 45% in partially control and 25% in uncontrolled state. According to MMSA scale, 20% of patients were high adherent to medicine, 40% were moderate adherent and 40% were low adherent. In this study, there was no significant correlation between the asthma control in terms of ACT and patients' educational level. Also, there was no significant relationship between sex, asthma control and medication adherence. In addition, there was no significant relationship between educational level and drug adherence.
Conclusion: The results suggest that there was no relationship between asthma control indices and patient's educational level. Perhaps other factors, other than education, affect the asthma control indices and medication adherence which requires more studies.
Hasan Ghobadi, Somaieh Matin, Ali Nemati, Hasan Javadi , Reza Alipanah-Moghadam , Mehdi Saeidi-Nir ,
Volume 19, Issue 1 (4-2019)
Abstract
Background & objectives: Chronic Obstructive Pulmonary Disease (COPD) is accompanied by systemic inflammations and is characterized by irreversible airflow limitations. Leptin is a cytokine with pre-inflammatory effect. However, there have been no studies on the effect of conjugated linoleic acid (CLA) on the serum leptin concentration in COPD patients. Therefore, the present study aimed to explore the effect of CLA on the serum leptin level, lung function and quality of life in COPD patients.
Methods: This interventional study was conducted on 90 COPD patients. The patients were randomly divided into two groups (supplement and placebo) with 45 patients per group. After obtaining written consent from the patients and recording their demographic characteristics, the spirometry was performed and COPD assessment test (CAT) score was calculated. Moreover, a fasting blood sample was collected from each of them in order to analyze their serum leptin concentration. After that, the patients in the supplement group were administered with 3.2 g/day of CLA for 6 weeks. The patients in another group received placebo. After the intervention, spirometry, CAT score calculation and blood sampling were repeated for all of the patients and the obtained results were analyzed.
Results: after the intervention, a significant decrease both in the serum leptin level and in CAT score as a quality life marker was observed in the supplement group (p<0.05). Moreover, the FEV1 levels as a lung function test, increased significantly in the supplement group after the intervention (p<0.05). Although, the difference between the two groups was not significant.
Conclusion: The use of CLA supplement can improve COPD patients’ quality of life through decreasing the serum level of leptin in their blood.
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