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Showing 50 results for Abi
Manoochehr Barak , Saeid Sadeghieh Ahari , Firouz Amani , Gholamreza Asadi, Gity Rahimi , Elham Khadem,
Volume 12, Issue 5 (11-2012)
Abstract
Background & Objective: Currently, migration of rural population to cities and developing slums around them are main problems in population settlement that lead to imbalance in health standards such as difference in age groups death. The aim of this study was to examine factors associated with infant mortality in slums of the Ardabil city. Methods: This was a case- control study. All infants’ deaths from 2008 to 2010, which occurred in slums as a case, were included. For each case, tow controls, were chosen. Controls the ones who survived and were living in non marginalized area and years of birth and sex were matched in two groups. Information collected from health centers through questionnaires, interviews with parents and child death files. Results: The majority of mortalities (74.6%) were in neonatal period and 25.4% was in post- neonatal period. The most important causes of deaths in neonatal were prematurity (57%), and in post neonatal period were congenital abnormality (35.4%). Analysis of effective factors showed that birth weight, parents age and education, family income and occupation and smoking of father were highly associated with mortalities. Conclusion: Infant mortality of the family that their father is a smoker and they have low income, and low parental education level is significantly higher and should be taken into serious consideration to reduce the mortality.
Ali Hossain Khani , Ali Nemati, Mitra Naser Saead , Shahnaz Hosseinzadeh, Manoochehr Barak ,
Volume 12, Issue 5 (11-2012)
Abstract
Background & Objectives : Urolithiasis is the third common urinary disease. While, relationship between the urinary stones and diet is known to some extent, but there are controversies about it. The aim of this study was to determine the association between food habit, nutrients intake and kinds of urinary stone disease. Methods: This cross-sectional and descriptive analytical study was performed on 150 patients (91 male and 59 females) with urinary stone disease in Ardabil during 2008-2009. Data of urinary stones analysis, type of stone in the graph, type of stone, preventive emprise and type of drinking water were recorded. Food data were recorded using 24-hour dietary recalls three days in week and food frequency questionnaires. Data were analyzed using SPSS, Food Processor III software, and ANOVA Statistical program . Results: Findings showed that the most common and lowest form of urinary stone disease in men and women were calcium oxalate and ammonium phosphate, respectively. There was significant inverse association between beta-carotene intake and the percentage of uric acid stone disease (p<0.05). We observed significant relationship between vitamin A and folacin intake with percentage of uric acid stone disease (p<0.05). There was significant relationship between consumption of cheese and pickles with calcium phosphate stone disease (p<0.05). There was no significant association between other foods and nutrients intake with types of urinary stone disease . Conclusion: This study showed the consumption of some nutrients including folacin, vitamin A and some foods such as cheese was associated with the incidence of urinary stone disease. Therefore, taking accurate diet could possibly prevent the incidence of urinary stone diseases.
Touraj Rahmani , Farid Bahrpeyma, Manoochehr Iranparvar , Mohammad Taghikhani ,
Volume 14, Issue 3 (10-2014)
Abstract
Background & objectives: Type 2 diabetes mellitus results in vascular dysfunction and reduction of nitric oxide (NO) level. In this study the effect of electromagnetic field (EMF) on NO level, an effective factor in increasing blood flow, and on ankle brachial index (ABI) as a n index of lower extremity blood flow in type 2 diabetic patients, have been investigated. Methods: This study was a randomized controlled clinical trial carried out in Imam Khomeini hospital of Ardabil and Mehr physiotherapy center in 2013. Thirty diabetic patients after initial pilot study participated in this experiment based on inclusion and exclusion criteria. Then, they were randomly assigned into two equal groups, electromagnetic therapy and control. The baseline levels of ABI and NO of both groups were measured. Patients in electromagnetic group were exposed to 10 Hz EMF radiation (with intensity of 8 mT) together with scanning lower limbs (three sessions per week, and 40 minutes per session for 8 weeks). The control group did not receive any treatment. After eight weeks, the amount of ABI and NO level were recorded. For statistical analysis paired t-test and independent t-test were used in SPSS 19 software. Results: Statistical analysis showed significant differences between pre (1.009±0.02) and post (1.052±0.02) measurement of ABI of diabetic patient after applying magnetic field ( P = 0.013). However, there was no significant difference between p and after measurement of ABI and NO level in controlgroup and also NO level in magnet groups ( P> 0.05). Difference between pre and post therapy of ABI in electromagnetic group (0.05±0.01) showed significant increase compared with control group (0.004±0.003) ( P = 0.001). Conclusion: Increase in ABI after 8 weeks electromagnetic therapy could be considered as an accretion index in blood flow in lower extremity.
Nasrin Fouladi , Farhad Pourfarzi , Jalal Tagizadeh, Hosein Alimohammadi , Raheleh Mohammadi,
Volume 14, Issue 4 (1-2014)
Abstract
Background & objectives: Addiction is one of the problems in world threating the social, economic and culture factors. It is essential to have an accurate knowledge about the characteristics of drug users in order to diminish the high-risk behaviors of intravenous drug addicts. This research has been done to assess relationship between individual characteristics and high risk behavior in intravenous drug addicts. Method: In this descriptive-analytic research, 360 drug users were selected from different places in Ardabil city and interviewed by a prepared questionnaire. The data were analyzed using descriptive and analytical tests including t-test, Pearson correlation and ANOVA with SPSS statistical software. Results: The results showed that the age, gender, material status, job position, age of addiction start, age of injection start, injection frequency, injection frequency per day, syringe supply place and the partner’s gender during recent few months had no significant difference compared to drug users with needle sharing and without needle sharing. The educational level of drug users with needle sharing was lower (P=0.037) and the number of new syringe usage per month was also lesser (P=0.001). They predicted to be more likely infected with AIDS (P=0.001) and had a less argument with their partner about using condom, also mostly have not used condom at their last sexual relationship (P=0.001). The average number of their partners during last three months was high (P=0.003) and there was a meaningful relationship between true sense of peril and using condom in drug users with needle sharing group (p=0.001). Conclusion: There is a significant relationship between the true sense of danger and the using condom. It is necessary to have an appropriate advertising to increase using condoms among injecting drug users.
Saadat Jalili , Mousa Aghaei, Akraossadat Saeid Mahdavi ,
Volume 14, Issue 4 (1-2014)
Abstract
Background & objectives: At the present time, health care services have been increasingly transformed to a competitive issue and many factors influence usage of hospital services and selection of a hospital by the patients. This study has been performed for surveying effective factors on selecting a public or private hospital among non-emergent patients of Ardabil hospitals in 2012. Method: This research was a cross-sectional descriptive-correlational study and the statistical population was non emergent patients of four public and two private hospitals of Ardabil in 2012. The samples (598 patients) were collected by stratified random sampling method. Data-gathering tool was a researcher-made questionnaire and data were analyzed by descriptive statistics, frequency [distribution] tables, and logistic regression analysis. Results: The results depicted a direct interdependence between selecting a hospital (public or private) and the three factors of social elements, hospital services, and hospital facilities with a confidence coefficient of 92%. Based on logistic regression analysis and Exp(B) coefficient, the patients’ priorities for hospital choosing were hospital services, social elements, and hospital facilities with Exp(B) of 1.932, 1.332, and 0.338, respectively. Conclusion: The most important factor for choosing public hospitals was lower cost of services and for private hospitals was physician’s recommendation. The strong effects of these two factors have overshadowed other variables.
Behnam Mohammadi-Ghalehbin , Kimyia Rahimi , Ali Pezeshki , Firooz Amani , Peyman Azghani , Soltan Asghari , Elham Raeisi ,
Volume 15, Issue 1 (4-2015)
Abstract
Background & objectives: Trichomonas vaginalis is a protozoan parasite lives and also causes symptoms in urogenital system of human. Trichomoniasis is the widest spread infection which is transmitted through sexual contact and more than 170 million people are a ffected with Trichomonas vaginalis in the world. Trichomonas vaginalis in women causes pelvic inflammatory disease, increase in the risk of fallopian tube dependent infertility, ectopic pregnancy, preterm labor, the birth of low weight infants and the increase in the possibility of HIV transmission. Considering the importance of Trichomonas vaginalis infection in pregnant women and lack of data from Ardabil city, this study was performed to identify this infection in pregnant women referred to health and medical centers of Ardabil city.
Methods: Vaginal discharge from 500 pregnant women was collected with sterile swap and disposable speculum and examined for Trichomonas vaginalis by direct microscopic examination and cultured in Diamond specific medium. A testimonial and questionnaire were completed for each case and the results analyzed using chi-square test by SPSS statistical software version 19.
Results: In this study, the culture of samples displayed 12 positive cases (2.4%). Furthermore, Trichomonas vaginalis trophozoites were observed in five cases (1%) with direct microscopic examination. Among 12 positive cases, five respondents (41.7%) were in age range of 16-25 years and seven (58.3%) in 26-35 years old. Among different clinical manifestations there was a significant relation between discharge and the infection.
Conclusion: The present survey confirmed the presence of Trichomonas vaginalis infection in pregnant women of Ardabil city. Therefore, an effective healthcare program by health authorities for prevention of infection in this group seems to be needed.
N Danesh Far , H Peeri Dogaheh, M Ghiamirad ,
Volume 15, Issue 2 (7-2015)
Abstract
Background & objectives: Resistant microbial strains are a serious threat to public health in different societies. A mong the extended-spectrum β-lactamases (ESBL) producing strains the Enterobacteriaceae family which is considered as the main factors producing urinary tract infections, have created many problems in treatment of this kind of infections. This study was conducted to determine the frequency of β-lactamase TEM-1 gene in Enterobacteriaceae isolated from urine samples in Ardabil city.
Methods: Within 6 months, 400 urinary isolates of Enterobacteriaceae of inpatients and outpatients were collected in Ardabil hospitals and were identified by standard methods. Antimicrobial susceptibility of isolates was tested by disk diffusion method, and ESBL producer confirmatory test was conducted using combined disk. Finally, the frequency of β-lactamase TEM-1 gene in producing extended-spectrum β-lactamases strains was investigated using PCR.
Results: From 400 isolates of Enterobacteriaceae, 150 cases (37.5%) were ESBL producing. PCR results showed presence of the TEM-1 gene in 69 cases (46%). The frequency of this gene in isolates of Enterobacter (Aerogenes, Cloacae), Klebsiella (Pneumoniae, Oxytoca) and E. coli was obtained to be 62.5%, 54.5% and 44.8%, respectively. Proteus mirabilis and Serratia marcescens strains were lacking these genotypes.
Conclusion: As regards the presence of TEM-1 gene, there is also increasing in other members of the Enterobacteriaceae family including Klebsiella and Enterobacter in addition to E. coli, therefore sufficient identification of this strains is necessary to prescribe the right medicine.
A Naghizadeh Baghi , M Khanbabazadeh Ghadim , E Samari,
Volume 15, Issue 3 (10-2015)
Abstract
Background & objectives: The most obvious indicators of a country's growth and development are technological capabilities and its scientific research . Therefore, any attempt to clarify the status of research and facing obstacles is important. The aim of this study is to investigate the problems and obstacles of knowledge from the viewpoint of faculty members of Ardabil University of Medical Sciences.
Methods: In a descriptive and survey study, sample contains 126 faculty members in Ardabil University of Medical Sciences were selected using Morgan and Krejcie table of sample size determination. The instrument used in this study was a questionnaire with two parts, i.e. demographic information and the Questionnaire of Research Barriers by Sotoodehasl et al. (2014) including 39 items on a 5 point Likert Scale continuum. A One-Sample T-Test, an independent samples T-Test, and an ANOVA test were used for the data analysis.
Results: The mean of the area of problems related to preparation of research project and development was 2.86 which is less than the conceptual mean but is not statistically significant (p=0.056). However in the other three areas, i.e. the means of problems in the implementation of the project, administrative and managerial problems, and individual problems were greater than the conceptual mean and the differences were statistically significant (p≤0.05). The mean of questions in the four areas was 3.23 which is greater than the conceptual mean and the difference is also significant (p=0.001).
Conclusion: In the investigation of areas, the most important problems and research barriers from the viewpoint of faculty members are weak teamwork at the university, large bulk of work and different expectations from the faculty members and lack of proper research environment.
E Raeisi, M Ghiamirad,
Volume 15, Issue 3 (10-2015)
Abstract
Background & Objectives: Salmonellosis is the most common food-borne disease in the world. The purpose of this study was to determine the prevalence of salmonella serogroups and their antimicrobial susceptibility patterns in chicken meat and viscera in Ardabil, Iran.
Methods: In this cross-sectional study done in spring and summer of 2014,260 samples) 160 chicken meat, 50 gizzard and liver) were collected for isolation and identification of salmonella. The technique used in this study was recommended by Iran standard organization andKirby-bauer method was also used for detection of antibiotic resistance.
Results: Amongallthe samples,the range of detected salmonella was 10%I n which the 42.3% of them detected in spring and 57.7% in the summer.92.3% of samples belong to C serogroup and 3.8% of them were serogroup B and 3.8% serogroup D. All isolates show resistance to at least two antibiotics. Concurrent resistance to 2-6 antibiotics was detected in 70% of the isolates. The highest resistance was to Nalidixicacid�and Streptomycin (100%)and toTetracyclin (92.3%), Penicillin (88.5%), Neomycin, Kanamycin and Furazolidon (84.6%), cloramfenicol (73.1%), Ofloxacin (15.4%), Co-Amoxi clave and Ampicillin (11.5%) and Siprophloxacin 7.7%. The lowest levels of resistance were for Gentamycin and Amikacin (3.8%). No salmonella isolates were resistant to ceftazidime, Azitromicin, Meropenem, Imipenem and cefixime.
Conclusion: According to 10% pollution to salmonella and prevalence of serogroup C and salmonella importance in the human&rsquos health, as well as high rate of antibiotic resistance of isolates, applying a health strategy for reduction of contamination level is necessary.
Shahram Dastouri Dastgir , Jaber Davoudi, Afshin Bahman Shabestari ,
Volume 16, Issue 2 (7-2016)
Abstract
Background & objectives: Pars Abad Moghan city, due to the mild weather and numerous Pastures for animals feeding, is a suitable place for breeding sheep and goat. Babesiosis is one of the most important parasitic infection in animals, especially ruminants. Babesia is a protozoa living inside the red blood cells and transmitted to the host by hard Tick especially Rhipicephalus, Hyalomma, Dermacentor and Haemaphysalis. The aim of this study was to consider Babesia infection in sheep of Pars Abad Moghan city.
Methods: In order to investigate the prevalence of babesia, 105 sheep in two different seasons of spring and summer were prepared and blood sample was taken and thin and thick smears were done. Thin blood smear was fixed with methanol and in order to determine the presence of the protozoan parasite, Giemsa with ratio of 1 to 14 in distilled water was used for staining.
Results: The results showed that the number of 33 samples (31.42%) were infected with Babesia. Among these, 18 samples (17.14%) were infected with Babesia ovis, 9 (8.57%) with babesia motasi and 6 samples (5.71%) were infected simultaneously with both species of Babesia ovis and Babesia motasi.
Conclusion: The rate of infection to Babesia among the sheep in Pars Abad Moghan city is remarkable. Early diagnosis and early treatment can prevent spread of the disease in this area.
Behnam Mohammadi-Ghalehbin , Hannane Javanpour Heravi , Mohsen Arzanlou, Mohammadreza Sarvi ,
Volume 16, Issue 4 (1-2016)
Abstract
Background & objectives: Candidiasis is a fungal infection which is caused by Candida spp. Candida albicans is the most common agent of candidiasis. This infection may cause various side effects during pregnancy including prematurity, chorioamnionitis, candidal pneumonia, and systemic candidiasis of infants. This research was conducted for determining the prevalence and antibiotic resistance pattern of Candida spp, collected from pregnant women admitted to health centers in Ardabil, Iran.
Methods: Totally, 408 subjects were included in this study. Demographic data and risk factors were recorded using a questionnaire. Two swab samples were taken from vulvovaginal mucus. One swab was used for preparing smear and direct microscopic examination and the second one used for cultivating the specimen. After identification of Candida spp., antimicrobial resistance pattern was determined by disk diffusion method against Fluconazole, Ketoconazole, Clotrimazole, Nystatin and Amphotericin B. Results were interpreted according to CLSI guidelines. The data were analyzed by χ2 and t-test using SPSS-19.
Results: Out of 408 subjects, 143 cases (35%) were positive for candida spp. The Candida albicans with 119 (83.2%) cases was the most prevalent species followed by Candida glabrata, Candida krusei, Candida parpsilosis and Candida tropicalis.According to disk diffusion test, overall 116 (81.1%) isolates were resistant to Fluconazole, 100 (69.9%) to Ketoconazole, 67 (46.9%) to Clotrimazole and 25 (17.5%) to Amphotericin B. Candida spp. had a highest sensitivity (118, 82.5%) to Nystatin. For Candida albicans 97(81.5%) isolates were resistant to Fluconazole and 99(83.2%) isolates to Nystatin. For Candida glabrata 10 (90.9%) isolates were resistant to Fluconazole, and 9(81.8%) sensitive to Nystatin.
Conclusion: According to the results of this study, vulvovaginal candidiasis is prevalent among pregnant women in Ardabil and isolates were significantly resistant against commonly used antifungal drugs. Nystatin was the most effective against Candida spp. As antibiogram for fungal agents is not routinely performed, the similar periodical studies could be useful for choosing appropriate antibiotics in treatment of vulvovaginal candidiasis.
Faranak Hasanpour, Kamaleddin , Hamidi , Saber Zahri, Saeeid Latifi Navid ,
Volume 17, Issue 2 (7-2017)
Abstract
Background & Objectives: Breast cancer is one of the most common cancers of women in the world. Apoptotic pathway is one of the most important pathways to deal with cell damage, especially cancer, which is usually blocked in this disease. One of the main enzymes to set up this pathway is JNK (1,2,3α,3β), which is activated by cellular stress.
Methods: In this study, breast cancer cells with the origin of MCF-7 cell lines were cultured in RPMI medium using 10%fetal bovine serum.Then , they were subjected to heat (42 & 45 ̊ C) for 1,2,4,6 and 8 hours under X-ray and γ-ray radiations for 1,2,3 and 4 hours as well. Their viability and enzyme level were evaluated by MTT and ELISA tests, respectively.
Results: The obtained results showed that abiotic stresses including heat and radiations resulted in JNK level increase and recovery of apoptosis pathway function in breast cancer cells. In addition, they led to decreased of cell viability and increase of JNK level depending on the duration and kind of stress.
Conclusion: The results in this study showed abiotic stress directly affected the JNK level. Increase of this enzyme in the cell resulted in activity of JNK apoptosis pathway. We hope to find methods to help to cancer treatment by means of more studies on JNK enzyme and relevant pathways.
Jinous Gamissi, Mohammadtaqi Masoumi, Adallat Hossinian,
Volume 17, Issue 2 (7-2017)
Abstract
Background & objectives: Coronary artery disease (CAD) is the most common cause of mortality and disability around the world. Determination of the health status and spatial and temporal patterns of the disease prevalence has a major role in health planning.
This study aimed to investigate the spatiotemporal pattern of CAD in Ardabil Province.
Methods: This descriptive and cross-sectional study was performed using the data belonging to 60156 patients with history of hospital admission due to CAD in Ardabil Province during 2010-2015. Hospitalization Rate (HR) was calculated after classification of the data in terms of location and date of hospitalization. The spatiotemporal and demographic variables, including age, gender, type of CAD, periods and duration of hospitalization were analyzed by descriptive statistics, ANOVA and repeated measures in SPSS v23 statistical software. Spatial distribution maps were drawn for each month and year in ArcGIS 10.2.
Results: Of 60156 hospitalized patients with CAD diagnosis, men (58%) were more in number than women (42%). The majority of hospitalized patients fell in the age range 60-69 years (25.3%), and 92.40% of patients were hospitalized for less than 7 days. An ascending pattern was observed in temporal hospitalization trend in Khalkhal and a descending trend in Ardabil. The lowest hospitalization rate, however, was observed in Kosar city despite the ascending trend. During the research period, the greatest decline in hospitalization rate was observed in temporal trend in Bilasuvar, Meshkinshahrand Namin cities, and the largest increase was observed in Germi, Pars-Abad and Kosar cities.
Conclusion: By using the comprehensive technology, GIS, spatiotemporal distribution and CAD trend during 2011-2015 were modeled in Ardabil province. Spatiotemporal trend of CAD in Ardabil province and allied cities indicated the necessity of paying more attention and studying community for further prevention of the disease. Community-based interventions should be implemented for prevention of risk factors of CAD during childhood and adolescence especially in the districts with high risk.
Reza Alipanah_moghadam , Sara Hosseinzadeh, Ali Nemati, Abbas Naghizadeh Baghi , Vadood Malekzadeh,
Volume 17, Issue 2 (7-2017)
Abstract
Background & objectives: The relationship between dietary patterns and esophageal cancer has not been documented yet. However, recent studies have shown that the Western dietary pattern is associated with an increased risk of esophageal cancer. The current study was performed a comparative evaluation of the food habits and serum nitrate level in patients with esophageal cancer and healthy individuals in Gorgan city.
Methods: In a case-control study, 44 patients with esophageal cancer (the case group) and 44 healthy subjects (control group) were selected for one year in Gorgan city. Anthropometric factors were measured, and then demographic and dietary data were recorded using general and food frequency questionnaires (FFQs), respectively. Fasting blood samples from both groups were collected to measure serum nitrate levels. Data were analyzed by independent t-test, Chi-square, Fisher, and Monte Carlo tests.
Results: the mean weight, body mass index (BMI) and serum nitrate levels were statistically lower in the case group than in control group (p<0.05). Salt intake, smoking cigarette or hookah was higher in patients than in control group (p<0.05). Based on nutritional habits , consumption of bread , rice, saturated fats, hot tea, sausages and industrial soft drinks was statistically higher in the patient group than control group, but intake of vegetables, fruits, unsaturated fats, honey and grilled meat was lower in patients than control group (p<0.05).
Conclusion: Consumption of fast foods, hot tea and saturated fats may be associated with esophageal cancer. Serum nitrate levels were lower in patients than control group, probably indicating the need for further research in this field.
Ziba Jahani, Seyyed Saeid Hosseini Asl , Homa Akhavan ,
Volume 18, Issue 1 (4-2018)
Abstract
Background & objectives: The spontaneous abortion, loss of the fetus until the twentieth week of pregnancy, is one of the most common medical problems in reproductive age. Approximately 15 to 20 percent of all clinically recognized pregnancies lead to abortion. Failure in pregnancy involves economic costs, physical and mental problems for the family and the society. Recurrent spontaneous abortion is a multifactorial phenomenon and this study analyzed chromosomal abnormalities and the prevalence of consanguineous marriages in parents with recurrent spontaneous abortions in Ardabil province.
Methods: A total of 350 patients with at least two spontaneous abortions were analyzed using GTG-banding cytogenetic technique.
Results: Parental chromosomal abnormalities were found in 18 cases (10.28% of couples). Most of abnormalities were structural (72.2%). chromosomal aberrations were found in 10 (55.6%) females and 8 (44.4%) males. Translocations were the most common chromosomal abnormalities (55.6 %) diagnosed in this study. Also, there was a significant correlation between recurrent spontaneous abortion due to consanguineous marriage and chromosomal abnormalities (p<0.05).
Conclusion: According to the significant correlation between recurrent spontaneous abortion and chromosomal abnormalities in this study and previous studies, and also the high rate of consanguineous marriages in Ardabil province population, analysis of chromosomal abnormalities is necessary after genetic counseling for both parents with recurrent spontaneous abortions.
Keywords: Recurrent Spontaneous Abortion; Chromosomal Abnormalities; Consanguineous
Manocher Iran-Parvar , Hasan Anari , Seyed Taha Ghoreishi , Mohammad Javad Naghi-Zadeh , Shadab Mirfakhrayi,
Volume 18, Issue 2 (7-2018)
Abstract
Background & objectives: Ultrasonography as a non-invasive, inexpensive and generally available method has been used to measure of the intima-media thickness (IMT) of carotid arteries changes and finding its relationship with cardiovascular risk factors and vascular diseases. The aim of this study was to investigate the carotid arterial wall thickness (IMT) changes based on clinical and para-clinical indexes in patients with type 2 diabetes mellitus (DM).
Methods: In this descriptive-analytical study, 100 patients with type 2 DM were randomly selected from all patients admitted to diabetes clinics and were considered in terms of clinical and paraclinical indexes of systemic atherosclerosis. Both types of IMT (TA and TB) were measured by ultrasonography in six locations of the carotid system. The intensity of these two values was calculated compared with the normal IMT and also, its relationship with clinical and para clinical indexes were determined. The results were statistically analyzed using SPSS software version 19.
Results: In this study, more than 80% of patients had IMT upper than normal. There was a significant difference between the severe increase of IMT and effective variables such as sex, smoking, physical inactivity, dyslipidemia and poor blood glucose control.
Conclusions: This study showed that the DM and factors such as sex, smoking, physical inactivity had a significant effect on the increasing IMT compared to the normal range.
Zahra Heidari, Roghaye Seyedhashemi, Behnam Mohammadi Ghalebin,
Volume 18, Issue 4 (1-2018)
Abstract
Background & objectives: Parasitic diseases are one of the health problems of all societies and are considered as barriers to progress socioeconomic development, especially in most developing countries. This study evaluated the frequency of intestinal parasites in patients referred to hospitals affiliated with Ardabil University of Medical Sciences in 2018.
Methods: a total of 409 stool samples were collected from laboratories of Imam Khomeini and Bouali hospitals and then transferred to the parasitology lab in the medical and paramedical school. Samples were evaluated using direct, concentration and culture methods. Data were analyzed using SPSS software version 21.
Results: Out of 409 samples, 22 cases (5.4%) were infected with intestinal parasites. Among them, 5.3% and 5.4% of infected cases were men and women respectively. Also, the rate of infection to the protozoans and helminths was 3.7% and 1.7% respectively. Among the positive cases, the highest percentage of infection was related to Giardia and Blastocystis.
The infection rate of each parasite among all patients and positive cases was 1.2% and 22.7% respectively.
Conclusion: The present study showed that intestinal protozoan infection, especially Giardia lamblia and Blastocystis hominis are high in Ardabil city, and therefore special infection control measures are urgently needed.
Farhad Salehzadeh, Afshan Sharghi, Atena Moteyagheni, Saeid Hosseini Asl, Mahsa Mottaghi, Sepehr Sarkhanloo,
Volume 19, Issue 1 (4-2019)
Abstract
Background & objectives: MEFV gene has a major role in Familial Mediterranean Fever (FMF) as an auto-inflammatory disorder. FMF is most often seen in the people of the Mediterranean area. Considering the significant role of the MEFV gene in many rheumatologic diseases and even non-rheumatologic disorders, it is necessary to identify different variations of these mutations in the healthy and normal population of this area.
Methods: 224 healthy people entered into this study. The blood samples were screened for the 12 most common MEFV gene variants according to manufacturer’s instructions. (FMF Strip Assay, Vienna lab, Vienna, Austria)
They filled a questionnaire containing the required information. All patients were initially evaluated for the FMF symptoms and signs in themselves and their first-degree relatives based on clinical criteria. Chi-squared test and t-test were employed for statistical analysis using SPSS ver.24.
Results: Among 224 cases, 113 cases (50.4%) were male, and 111 cases (49.6%) were female. MEFV mutations were detected in 57 patients (25%) of them, 28 cases were male (49.1%) and 29 cases were female (50.9%). The most frequent mutations were E148Q (18.3%, 41cases), followed by P369S (3.1%, 7 cases), V726A (2.2%, 5cases), A744S (1.3%, 3cases), F479L, M694V and R761H (0.8%, each 2 cases), and eventually K695R (0.4%) respectively. Some mutations such as M694I, M680I (G/C), M680I (G/A), I692del were not seen in these samples. There were compound heterozygous mutations of E148Q/P369S, E148Q/V726A, E148Q/P369S, and P369S / F479L in normal population without any findings in favor of FMF.
Conclusion: Twenty-five percent of the normal population of the northwest of Iran carrying a heterozygous variant of the MEFV gene, E148Q (18.3%) as a most common mutation, which can be considered as a normal variant in the healthy population. The presence of M694I, M680I (G/C), M680I (G/A) and I692del mutations in the normal population can be interpreted with cautiously, while particular compound heterozygous mutations can be considered as normal variants.
Iraj Feizi, Somaieh Matin, Hasan Ghobadi, Saeed Hosseininia, Susan Mohammadi Kebar, Farideh Feizi, Hossein Salehzade,
Volume 19, Issue 3 (10-2019)
Abstract
Background & objectives: Hydatid cyst is a major hygiene problem in Iran. In 80% of cases, only one organ is involved. However, multiorgan involvement has also been rarely reported. But it seems, the prevalence of hydatid cyst with the involvement of more than one organ in Iran is more than other world. The aim of this study was to evaluate the patients with hydatid cyst multi organ involvement in Ardabil province in northwest of Iran.
Methods: In this retrospective study, 34 patients with hydatid cyst with involvement in more than one organ were included. For each patient, a pre-designed questionnaire including name, age, education level, occupation, place of residence, cyst location, clinical manifestations and serologic test results were completed. Patients, who had previously a history of treatment due to hydatid cyst, were excluded from the study.
Results: The mean age of patients was 36.41 years. 61.8% of the patients were housewives and 64% were rural residents. The most commonly involved organs was liver and simultaneous involvement of liver and lung was observed in 38.2% of patients and was more in women. The association of the right lung cyst with the liver cysts was greater than that of the left lung. Only in 43% of the patients, the serologic test was positive for hydatid cyst, and the relationship between serologic test and type of involvement was not significant.
Conclusion: Regarding the high incidence of hydatid cyst involvement in more than one location in our region, in all patients, especially women with liver hydatid cyst, other organs, especially the lungs, should be investigated
Anoushirvan Sadigh, Ebrahim Fataei, Mohsen Arzanloo, Ali Akbar Imani,
Volume 19, Issue 4 (1-2019)
Abstract
Background & objectives: The purpose of this study was to determine the bacterial bioaerosols in indoor air of Ardabil universities and to investigate the factors affecting their concentration in Ardabil city.
Methods: Air sampling was performed using Andersen single-stage sampler at a flow rate of 28.3 liters per minute and a respiratory range of 10 min. In this study, trypticase soy agar containing cycloheximide antibiotic was used for bacterial culture. Biochemical tests such as DNase, catalase, oxidase, coagulase, bile esculin hydrolysis test, urease, citrate test, antibiotic resistance to novobiocin, bacitracin and optochin were used for identification and differentiation of isolates.
Result: The mean bacterial concentration in Ardabil university of medical sciences in the open air, outside the college, the halls, the classrooms and the staff rooms was 18, 88.4, 76.6, 77.4 CFU/m3 , respectively. The concentration of bacteria in Islamic Azad university of Ardabil in the open air, outside the college, the halls, the classrooms and the staff rooms was 103, 97, 124, 132 CFU/m3, respectively. The dominant species of bacteria in indoor air were Staphylococcus aureus, Staphylococcus epidermidis, Actinomycetes and Bacillus, respectively.
Conclusion: According to the results of this study, it is found that the concentration of bacterial bioaerosols in indoor air is not more than standard, but the abundance of bacterial species can cause lung, intestinal and other diseases in academic personnel, staff and students in the long-term.
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