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Showing 167 results for No
Khosro Hazrati Tappeh , Mohammad Rahbar , Sasan Hejazi, Mahiar Mostaghim ,
Volume 5, Issue 4 (12-2005)
Abstract
Background & Objectives: Cryptosporidium is a coccidial protozoa parasite belonging to subphylum of Apicomplexa. Although it is globally widespread and its species exist all over the world, this parasite was unknown until several years ago. Nowadays it is considered as an important infective agent in Immunocompromised hosts especially patients with AIDS. Due to high mortality rate of this infection in immunocompromised and cancerous patients and because of the popularity of Urmia as one of the animal husbandry regions in Iran and since this disease is likely to transfer from animals to human beings this study was conducted to determine the rate of contamination with this parasite. Methods: This case-control study was performed on 72 children (case) with cancer who referred to oncology clinic of Urmia Imam Hospital during 2001. Another 30 children with normal immune system were selected as controls. To determine the amount of contamination with parasite, two fecal specimens were collected from each patient. After being concentrated with Formalin–Ether, these specimens were examined using modified acid fast method. Results: Three cases ofcryptosporidiosis was seen in the patients (4.16%). Of these, there were 2 patients from the rural area and 1 from urban region. There was no significant relationship between the presence of cryptosporidiosis and living in rural or urban areas. Conclusion: Cryptosporidium was detected in three cases of the patients under study who were undertaking chemotherapy. However since the population under study was small, no statistically significant relationship was found between being immunocompromised and contamination with parasite.
Parvin Yavari, Uadollah Mehrabi, Mohammad Amin Pour-Hoseingholi ,
Volume 5, Issue 4 (12-2005)
Abstract
Background & Objectives: Breast Cancer is among the most common types of cancer in women which in case of early diagnosis and treatment can increase women’s chance of survival. This study was performed in two case and control groups. Methods: This case-control study which was based on hospital records was conducted on 303 breast cancer patients and 303 control women. The collected data were analyzed by SPSS using Chi-square. Results: The study revealed that there were significant differences between the cases and controls with regard to knowledge (p<0.001) and practice (p<0.001) of breast self-examination. 61% of the cases and 32% of the controls mentioned BSE as a necessary measure for the early diagnosis of breast cancer. 76% of the cases and 47% of the controls were not aware of the proper time for BSE (p<0.001). More than two-third of the subjects in each group did not know the proper time and the necessity of BSE in menopause and pregnant women and these was a statistically significant difference between two groups in this regard (p<0.001). Women in case group had done more frequently than controls (p<0.04). Moreover, the BSE intervals in two groups was statistically significant (p<0.01). There was also a significant difference between the reasons of refusing to do BSE in two groups (p<0.05). Subjects in neither group had regularly referred to a physician for examination and early diagnosis. Conclusion:Since the knowledge and practice of women and their referring to a physician for breast examination is inadequate, it seems necessary to devise educational program about doing monthly BSE and hold educational courses to promote women’s knowledge concerning the early diagnosis of breast cancer as well as its appropriate and regular performance.
Seid Hadi Hakim, Gahanbachsh Samadikhah , Samad Gafari , Azin Alizadeh ,
Volume 6, Issue 1 (4-2006)
Abstract
Background & Objectives: Thrombosis with high mortality is a serious complication of prosthetic heart valves and requires treatment, which includes reoperation or using filbrinolytic medications. Regarding the importance of the issue and high mortality rate in reoparation, the present study was performed to determine the efficacy and pragnosis of fibrinolytic therapy on mechanical prosthetic valve. Methods: This prospective study was preformed on seventeen patients with PVT who had undergone treatment with streptokinase (SK). After the primary diagnosis, the response to treatment was echocardiography and TEE. Patients with large clots or equal to 1cm clots, pregnant women and patients who had been operated in a month prior to the study were excluded. Results: Of the 17 patients (9 female and 8 male, mean age= 43.8 ± 11) 14 had mechanical double-let prostheses (8 mitral & 6 aortic) and 3 patients had single-let prostheses (1 aortic and 2 mitral). 71.3% of the patients with a double-let prosthesis responded completely to the treatment with SK. In none of the patients with a single-let prosthesis the treatment was successful. Also treatment of acute thrombosis was more effective in aortic position (71.4%) than in mitral– valve (50%) (p=0.02). Mortality rate due to cerebral bleeding was 5.8%. Two systemic embolic events (11.8%) occurred (1 cerebral and 1 renal) with transient signs. Conclusion: The use of fibrinolytic agents was effective, relatively safe and available especially in patients with less than two weeks’ presentation, small clot and NYHA class I and II and in aortic-position thrombosis.
Hosein Doostkami , Adalat Hosseinian, Gholam Hosain Fatehi,
Volume 6, Issue 1 (4-2006)
Abstract
Background & Objectives: Coronary artery diseases are the leading causes of mortality and morbidity in industrial countries and in Iran. Myocardial infarction and unstable angina are essential clinical syndromes of coronary artery diseases, with the difference that the mortality and morbidity of NonST-elevated myocardial infractions is more than U/A and requires more intensive care. Rapid differentiation and diagnosis of NSTEMI from U/A plays a major role in effective treatment of patients and improvement of their prognosis. This study was designed to determine the incidence of nonST-elevated MI among patients hospitalized with initial diagnosis of U/A. Methods: This is a descriptive and analytical study performed on patients hospitalized with U/A diagnosis between 2001 and 2002 in Ardabil Buali hospital. The data (including demographic characteristics, patients’ clinical findings, ECG changes, laboratory findings) were collected using a questionnaire and analyzed by SPSS software using descriptive and analytical statistics. Results: mean patient age was 61 and prevalence of nonST-elevated MI among patients with U/A was 23 patients (22.1%). Mean age of patients with NSTEMI was 60.5 and its prevalence was greater in male (69.9%) than in female (30.4%). The most prevalent ECG change in patients was T wave inversion and ST depression (78.3%) and in U/A patients it was T wave inversion (60.5%). The difference was statistically significant (p<0.001). 64.7% of the NSTEMI patients and 27.4% of the patients with U/A had severe chest pain (p<0.004). Conclusion: Prevalence of NSTEMI was about 1/5 of patients hospitalized with diagnosis of U/A and ECG changes among these patients (as T wave inverison and ST depression along with negative T wave) is more prevalent compared to those with U/A. Clinical manifestation and complications were more severe in these patients than U/A group.
Ali Majidpour, Shahram Habibzadeh , Firooz Amani , Fateme Hemmati,
Volume 6, Issue 1 (4-2006)
Abstract
Background & Objectives: Acquired immunodeficiency syndrome (AIDS) with a history of only three decades, has turned into a threatening pandemic disease world wide giving rise to 3.1 million deaths in 2005. Since there is no distinctive treatment or effective vaccine for AIDS, its epidemiology is similar to non-communicable and behavioral diseases. Since accurate knowledge and attitude is necessary for a healthy behavior, we conducted this study on high school students of Ardabil to determine their sources of acquiring information on AIDS as well as to find out their attitude and knowledge about this disease. Methods: This descriptive and cross-sectional study was conducted on 800 students in Ardabil high schools during the year 2002 using cluster random sampling method. A questionnaire with 4 groups of questions including demographic information, source of information used for AIDS and the amount each source is used as well as attitude and knowledge of the participants regarding AIDS was distributed in the school. The collected data were analyzed using SPSS. Results : 378 (47.2%) out of 800 students were girls and the rest of them were boys. The media used for getting informed about AIDS was determined to be: 84.5% TV, 51.4% newspapers and magazines, 49.6% papers and books and 30.6% radio. 89% of the girls and 67% of the boys used TV. The difference was statistically significant(p<0.001). Sources of information in interview form were found to be health care workers with 17.7%, teachers with 10.2%, friends with 9.5%, religious authorities with 8.6%, family members with 8% and other relatives with 5.6%. A combition of the above-mentioned methods plus other souces formed 41.3% of the information source of the students about AIDS. Only 46.3% of the students had a proper insight in their interaction with role-playing patients of AIDS. 44% of the participants had weak and 56% had moderate knowledge about transmission ways of HIV and no one had good knowledge in this regard. There was no significant difference between age, sex and knowledge. The highest percentage of moderate knowledge score was seen in student studying experimental sciences. Only TV had a significant correlation with knowledge (p=0.001). Conclusion: This study entails that more attention must be paid to education through effective use of TV broadcasting. Films, pictures, teachers, clergymen, radio, books and papers had not an effective educational role among high school students regarding AIDS.
Abbas Abolghasemi, Azar Kiamarsi,
Volume 6, Issue 2 (6-2006)
Abstract
Background & Objectives: The cognitive processes such as attention, thinking, memory and recall have effective role on the child’s confrontation with daily life problems. The psychological disorders are among those impairments which may severely affect these processes. Researches have shown that schizophrenia can impair children’s cognitive processes to a great extent. The aim of this research was to compare the comprehension, lexical Knowledge, memory and recall in children with schizophrenia, conduct disorder and brain damage. Methods: The sample of this causal-comparative research consisted of 80 children (8-13 years old) suffering from schizophrenia, brain damage and conduct disorder as well as a group of healthy ones who were selected from among in and out-patients referring to psychology and neurology wards of Emam Hossein health care center in 2004 (20 subjects in each group). The instruments employed in this research were WISC-R (comprehension, vocabulary, digit span) and Recall Test of Babcoch. Results: The one way analysis of variance showed significant differences between the children with schizophrenia, conduct disorder, brain damage and non-patient in comprehension, lexical knowledge, memory and recall (p<0.01). The LSD test showed that comperhension, lexical knowledge, memory and recall in children with schizophrenia were more impaired compared to children with conduct disorder and brain damage. Moreover, comprehension, lexical knowledge and memory in children with conduct disorder were more severely impaired than children with brain damage. However, the recall was better in children with conduct disorder than those with brain damage (p<0.01). Conclusion: The results showed that schizophrenic children have comprehension, lexical knowledge, memory and recall more impaired than those suffering from conduct disorder and brain damage. The timely recognition of the cognitive abnormalities seems necessary to have a better diagnosis and choose effective treatment and remedial strategies to cope with them.
Ahad Azami , Abbas Yazdanbod, Nateg Abbasgolizadeh, Yegane Sadeghy,
Volume 6, Issue 2 (6-2006)
Abstract
Background & Objectives: According to a recent report published by the ministry of health, Esophageal cancer is the second most common fatal cancer in Ardabil. This study investigated the relationship between anatomical sites and pathological features of Esophagus cancer with related risk factors. Methods: This descriptive-cross-secional and prospective study was conducted on patients referring to GI clinic of Ardabil (Aras) between 2000-2003. Patients with suspicious upper GI symptoms underwent upper GI vide-endoscopy. At least five to six endoscopic punch biopsies were obtained from all the lesions and sent for pathology. Diagnosis was confirmed by pathology. Anatomical sites, demographic information of the patients (age, sex, educational state, residential area) smoking habit, alcohol and opium consumption were entered into the questionnaire. Statistical analyses were performed using the EPI 2000 statistical software. Results: The mean age of the patients with cancer was 59 ± 11.64 years and the male to female ratio was 1:1. Villagers constituted 117 (77%) of the patients. 93.4% of these patients were illiterate. The cancers were of the following types: 126 (82.9%) SCC, 25 (16.4%) adenocarcinoma and 1(0.7%) in situ carcinoma. The most common site of esophageal SCC cancer was middle third of esophagus with 73 (48%) patients. In contrast the most common site of adenocarcinoma in 31 (20%) patients was lower third of esophagus. No meaningful relationship was found between esophageal cancer and smoking drinking or opium consumption. Conclusion: The findings indicated that unlikewestern countries esophagus cancer had no relationship with smoking or alcohol consumption in Ardabil. Other studies are recommended to be performed to find out more about relationship between known esophageal risk factors including nutritional habits, nitrosamines, soil contents, agricultural products and genetic background.
Mahdi Farhoudi , Mohammadkazem Tarzamani , Khandan Ghannadi Emami ,
Volume 6, Issue 2 (6-2006)
Abstract
Background & Objectives: Cerebrovascular diseases are the most common disabiling neurologic disorders and the third cause of death in the population over 45 years of age. Most of the strokes in adults are ischemic and almost one-fifth of them are due to intra- or extracranial internal carotid artery stenosis. Ultrasonography is a noninvasive, cost-effective and safe technique for evaluation of intra or extracranial vessels that is available in two methods: TCD and carotid Duplex. The present research is an attempt to investigate the appropriatens and comprehensiveness of TCD in diagnosing symptomatic significant carotid stenosis. Methods : This descriptive-analytical study was conducted on fifty patients admitted to the neurology ward of Imam Hospital who underwent both carotid duplex and TCD examination. Variables of blood flow velocities, collateral flow evidences and degree of carotid stenosis were assessed with both methods. The data were analyzed by SPSS (ver.11.5) using T.test, Chi-square and Fisher test. Results : 34 patieuts were. Male mean age of the patients was 66.70% of the subjects were above 65 and 68% of them had a history of hypertension. No statistically significant difference was seen between systolic and diatolic blood flow velocity in internal carotid artery and pulsatile index obtnined from reported by TCD and carotid Duplex. There was no statistically significant difference between the percentage of stenosis TCD finding of the patients with carotid stenosis showed collateral flow in 78.57% of the cases. Conclusion: Acceptable correlation of the flow velocity parameters and the percentage of carotid stenosis between TCD and Carotid Duplex results showed that the primary performance of TCD to diagnose significant carotid stenosis (that causes hemodynamic disorder) and screen ischemic cerebrovascular accident is a reliable and effective method, but for precise determination of stenosis, plaque typing and for diagnosing stenisis below 50% the performance of carotid duplex study is also necessary and to complemantory TCD.
Akram Kooskki, Mahdi Golafrooz Shahr ,
Volume 6, Issue 3 (9-2006)
Abstract
Background and Objectives: Oxidative stress has a role in the pathogenesis of type II diabetes due to increase in insulin resistance or disorder in insulin secretion and atherosclerosis. Food antioxadants including carotenoids protect against diabetes by preventing oxidation reactions. Therefore, this study was conducted in Sabzevar to study the relationship between carotenoids and blood sugar and lipids in type II diabetic patients. Methods: This cross-sectional analytical study was conducted on type II diabetic patients who were randomly sampled. Their height and weight were measured and relevant data on nutritional intake and frequency in 3 successive days were collected through 24-hour recall. Measures were domesticated and converted to grams. Carotenoids of the intakes were calculated. Blood sugar, triglycerides and serum cholesterol after 12 hours fasting were measured through enzymatic procedures. Data analysis was carried out by descriptive statistics and partial correlation. Results: 75 type II diabetic patients with mean age of 54.05±14.2 years, mean BMI of 27.02±5.03 Kg/m2 participated in the study. Their mean blood sugar, triglyceride and cholesterol were 196.36±87.82, 262.84±147.89 and 243.98±60.76 mg/dl respectively. Mean daily intake of beta carotene was 1236.56±810.21 mcg, alpha carotene 878.170±149.04 mcg, lutein 1163.40±819.77 mcg, zeaxanthin and lycopen were 2195.77 ±988.70 mcg. Conclusion: Our results showed that most carotenoids negatively correlated though not significantly with their blood sugar and lipids.
Sima Khavandizadeh Aghdam ,
Volume 6, Issue 4 (12-2006)
Abstract
Background & Objectives:Different studies have emphasized the psycho-social aspects of delivery, so that these aspects are no less important than medical and midwifery factors. This is a quasi- experimental study, the main objective of which was to evaluate the effects of the continuous labor support from a supportive companiom on the process and outcome of labor in primigravida. Methods: 50 women in supported group (case) and 50 without supporative companion (control) were selected. All women were between 18-30 years, and had term pregnancy, single fetus, cephalic presentatation or spontaneous onset of labor without any complications. The supportive companions were students of midwifery. The support consisted of talking, touching, reassurance, soothing, giving encouragement and physical comfort (e.g, helping to change position, keeping lips wet and cooling). The data were analyzed using student t-test, chi-square and Fisher test. Results: The findings showed that the continuous labor support by a companion reduced length of active phase (p<0.01), cesarean section (p=0.026) and increased APGAR score in the first minute (p=0.015) and led to the early onset of breast feeding (p<0.01). Duration of second labor and fifth-minute Apgar were not significantly different in two groups. Conclusions: This study showed that the continuous labor support can result in better outcomes in deliveries.
Maryam Zakeri Hamidi , Saeideh Zeiyaei , Anooshirvan Kazem Negad ,
Volume 6, Issue 4 (12-2006)
Abstract
Background & Objectives: Dysmenorrhea is a common complaint among women, which is occasionally accompanied by gastro-intestinal problems. This study was designed to consider the therapeutical effects of vitamin E on gastro-intestinal symptoms such as nausea, vomiting and diarrhea due to primary dysmenorrhea. Methods: This was an experimental randomized study. A questionnaire was given to three hundred girl students suffering from primary dysmenorrhea. Then 128 girls who had gastro- intestinal symptoms accompyning dysmenorrhea entered the study. 69 subjects were assigned to case group and 59 to control group. From two days before the period until three days after it, four pills of vitamin E (400IU) daily were given to the case group and four chewing placebo were given to the control group as well, for four months. The data were analyzed by SPSS using Chi-square test. Results: The findings showed no significant difference between the two groups in terms of gastro-intestinal symptoms after two months of treatment. But after four months of treatment there was a significant difference in the gastro-intestinal symptoms between the two groups (p=0.001). Conclusions: Vitamin E is effective to be used after the second month of treatment to treat the gastro-intestinal symptoms in girls with primary dysmenorrhea.
Ghodrat Mohammadi, Masoud Naderpoor ,
Volume 6, Issue 4 (12-2006)
Abstract
Background & Objectives: Otosclerosis is one of the causes of conductive hearing loss in different ages, the diagnosis of which sometimes becomes difficult using clinical and audiological symptoms. The early diagnosis and surgical treatment of this disorder will give a normal hearing to the patient. The goal of this study was to determine the role of exploratory tympanotomy in revealing the patients with hearing loss as a result of otosclerosis which is impossible to be diagnosed based on clinical and audiological, symptoms. Methods: This prospective study was conducted on 33 patients (18 females and 15 males) with conductive hearing loss suspected to otosclerosis, who were admitted to oto-rhino-laryngology department of Imam Khomeini hospital from 1999 to 2003 and underwent exploratory tympanomy. In 30 patients (16 females) otosclerosis was revealed during operation all of these patients underwent stapedectomy. During three weeks after surgery, the patients were examined in terms of facial paralysis, non-response to treatment, deterioration of hearing ability, dizziness, the probability of tympanic perforation and other complications. Audiological tests were also studied. The obtained data were recorded and compared with findings of other researches. Results:The prevalence of the disease in women was more than men, and the majority of the patients had referred to be treated in the third and fourth decade of their life, while they had a history of hearing loss from the second or third decade of their life. The positive family history was below compared to other studies, but conductive hearing loss was more prevalent. This treatment led to hearing improvement in majority of the patients. Conclusions: Considering the proper time for stapedectomy is very important since better results can be abtained if the patients are operated with lower degrees of hearing loss. Thus, exploratory tympanotomy leads to early diagnosis and treatment in patients with conductive hearing loss suspected to otosclerosis.
Farideh Mostafazadeh , Mehrnaz Mashoufi , Masoumeh Rostamnegad ,
Volume 6, Issue 4 (12-2006)
Abstract
Background & Objectives: Ceasarean section (CS) has increased in rate during the past years. Due to postoperative complications, long recovery time and high costs of surgery, normal delivery is recommended as a routine method. Regarding the increase in the number of CS and its acceptability on the part of the public, it seems that women’s as well as health personnels' attitudes play an effective role in selecting the termination method. The aim of this study was to evaluate and compare pregnant women’s and health personnels' attitude toward termination procedures. Methods: This was a descriptive and comparative study. 84 health personnels and 300 pregnant women who referred to Ardabil health centers in 2002 were selected. These subjects' attitudes were collected through Likert questionnaire and the collected data were analyzed by SPSS, using t-test. Results: The findings showed that 30.1% of women and 50% of health personnels had positive attitudes towards normal delivery. The findings also indicated that there was a significant difference between pregnant women and health personnels in their attitudes toward normal delivery and cesarean (p=0.001). Conclusions: Since health personnels had a more positive attitude towards normal delivery than pregnant women did, it seems that the young as well as the pregnant individuals in society need more education and awareness to be able to change their attitudes towards delivery methods. Health personnel, due to their high positive attitude towards normal delivery, can play a more beneficial role in this regard.
Hasan Anari, Farhad Salehzadeh , Ramin Mirmohammadi , Simin Monshari ,
Volume 7, Issue 1 (4-2007)
Abstract
Background & Objective: Developmental dislocation of hip (DDH) as an inherited joint disorder results from external location of the head of femora from the acetabulum.Early diagnosis of this disorder is very important and any delay may result in long life handicap. Nowadays new methods such as sonogrphy are recommended in diagnosis of this disorder. Radiology and physical examination are traditional methods. This study was designed to evaluate the results of sonographical, radiological and physical examination findings in 100 infants who were suspected to have DDH. Methods: This analytical-cross sectional study was done in private clinics from June 2004 to June 2005. The one hundred infants who were suspected to have DDH in physical examination entered the study. A questionnaire was completed for each infant, and then sonography and radioghray have been done for them. The data were collected and analyzed by statistical programs. Results: Among 100 infants 48% were female and 52% male, with mean age 42±7.23.In 44% they were the firstborn.58% had normal delivery and 42% cesarean section. 15% had breech presentation. In 28% radiological and 56% sonographical methods showed findings in favor of DDH. Conclusion: This study showed, simultaneous physical and sonographic examination especially during the first month result in early and precise diagnosis of DDH, on the other hand it does not have radiologic side effects.
Mokhtar Mokhtari , Mehrdad Shariatie , Nazanin Tadayon ,
Volume 7, Issue 1 (4-2007)
Abstract
Background & Objectives: Spironolactone is a diuretic and antiandrogenic drug and is used in the treatment of hypertention 'secondary hyprealdosteronism congestive heart failure' cirrhosis of the liver, nephrotic syndrome 'androgenic alopecia' gynecomastia and hirsutism. In this research, the effects of spironolactone on the serum LH, FSH, testosterone, dihydrotestosterone, and changes in body weight and testicular tissue in adult male rats, were studied. Methods: For this purpose 190 10 g male wistar rats (n=40) were randomly divided into the following grups: control, sham operated (received water) and 25, 50, 100 mg/kg oral spironolactone treated groups. After 14 days body weight and testis weight under laboratory methods, were measured and blood samples were taken from heart and used for the measuring of LH/FSH/testosterone and dihydrotestosterone and then the rates' testes, in order to evaluate the histological changes, were removed and weighed and after obtaining tissue section and staining through HE, they were studied. Results: Serum LH level showed a significant increase and testosterone and dihydrotestosterone levels showed asignigicant decrease in 100mg/kg spironolactone treated group ( p 0.05 ) and there was no significant difference among serum FSH level, body weight and testicular weight as compared to control group. Conclusion: It can be concluded that oral administration of spironolactone maximum dose for 14 days could increase serum LHlevel and decrease testosterone and dihydrotestosterone levels.
Mohammadreza Nahaei , Reza Bohloli Khiavi , Mohammad Asgarzadeh, Alka Hasani , Javid Sadeghi, Mohammad Akbari Dibavar ,
Volume 7, Issue 1 (4-2007)
Abstract
Background and Objectives: Pseudomonas aeruginosa is a nosocomial pathogen that presents high antibiotic resistance.There are phenotyping and genotyping methods for epidemiologic study of Pseudomonas aeruginosa such as antibiotic resistance pattern and plasmid profile analysis. Plasmid analysis provides useful information concerning the source of the strains and number of clones present in the epidemies. Thus, this study was conducted to evaluate antibiotic and plasmid profiles of P. aeruginosa strains isolated from in-patients of the Sina Medical Centre of Tabriz to clarify epidemyological correlation among isolated strains. Methods: During 13 months, 135 strains of P. aeruginosa were isolated from different infections in hospitalized patients at Sina Medical Center of Tabriz. Antibiotic susceptibility tests were performed using disc agar diffusion test. For plasmid DNA extraction and detection of open circular bands from supercoiled ones, modified alkaline lysis procedure and two dimensional electrophoresis were used, respectively. Enzymatic digestion of plasmids was carried out by EcoRI and HincII restriction enzymes. Results: Resistance rates of strains against antibacterial agents were recorded as: Aztreonam (77%), colistin (74%), ceftazidime (69%), pipracillin (67%), ofloxacin (62%), tobramycin (56%), carbenicillin (54%), gentamicin (51%), ciprofloxacin (22%), amikacin (15%), polymixin B (13%) and imipenem (2%). Plasmid profiles of our test strains revealed that only 67 strains harbored plasmid(s). Number of isolated plasmids ranged 1-6 in each strain with molecular mass of 0.5kb-21kb. When the isolated plasmids were digested using restriction endonuclease enzymes (EcoRI and HincII), in 32% of them similar digestion profiles were obtained by EcoRI indicating a unique source for them. Conclusion : Our findings suggest high antibiotic resistance and plasmid presence in P. aeruginosa strains isolated from different infections, and there were remarkable similarities among isolated plasmids. Since our test strains had been isolated from various wards in a short period of time, the results raise the possibility of unique source for some strains or high prevalence of genetic exchange among P. aeruginosa strains.
Hosein Dostkamy, Raeouf Mollajavad , Ahad Azami ,
Volume 7, Issue 2 (6-2007)
Abstract
Background & objectives: Hypertension is a disease with high prevalence and complications and unfortunately the freatment of which is not desirable in many communities including ours. The aim of this study is to assess the therapeutic diet giving and level control of HTN in patients with Hypertension who refered to Ardabil Boali Hospital emergency room and out patient Clinic room. Methods: This study was performed on 200 patients who refered to the emergency room and out patient Clinic in Ardabil Boali Hospital from 2003 to 2004 due to high blood pressure. In this study, blood pressure and other factors such as sex, age and the therapeutic modality including compliance to theyapy and kind and quality of drugs were determined, then the data was analyzed by using descriptive statistics. Results: Of 200 patients only 1% did not take drug 59.5% of patients were on monotherapy and 39.5% took two or more drugs 33.5% were on Beta blocker (Atenolol) and 11% on ACE inhibitor (Enalapril). Among patients on combination therapy the highest prevalence was B.bloche and ACE.I 40%, and the least one prevalence was diuretic and CCB (2%). All patients on diuretic were pre hypertensive whereas the majority of patients on CCB had stageII hypertension. In patients on multi drug therapy all patients on diuretics + CCB were pre hypertensive but 57% of patients on ACEI + CCB or ACE.I + diuretic had stageII hypertension. Conclusion: In this study for combination therapy Diuretic and CCB had the best result in controlling hypertension.
Kavian Ghandehari , Ashfagh Shuaib ,
Volume 7, Issue 2 (6-2007)
Abstract
Background & Objectives: Atherosclerotic stenosis of carotid territory is the most common cause of ischemic stroke. A higher frequency rate of intracranial arterial stenosis in African and Far East races has been reported. Methods: This double center and prospective study was carried out in 304 geriatric ischemic stroke patients admitted in Mackenzie Hospital, Canada and the same number of geriatric ischemic stroke patients with similar sex ratio admitted in Valie-Asr Hospital, Birjand during 2003-2005. The cause of brain infarction in carotid territory was made by neurologists was vasular origin. All of the patients underwent transcranial and carotid doppler studies based on the standard method by a neurosonologist. Topography of arteriosclerotic stenosis in bilateral Internal Carotid Artery (ICA) territories was determined. Fisher exact test served for statistical analysis and p<0.05 declared as significant. Results: In Iranian group 71 patients (23.3%) and in North American group 83 patients (27.3) had extracranial ICA stenosis without a significant difference p=0.3, df=1, OR=0.81, 95%CI(0.56- 1.17). Sever ³ 70% extracranial ICA stenosis was found in 14 Iranian patients (4.6%) and 23 North American patients (7.5%) without a significant difference . p=0.17, df=1, OR=0.59, 95%CI(0.3-1.77). In Iranian group, 14 cases (4.6%) and in North American group 5 cases (1.6%) had intracranial ICA territory stenosis which had a significant difference p=0.038, df=1, OR=2.9, 95%CI(1-8.1). Mixed intracranial and extracranial ICA territory stenosis was found in 2 Iranian and 1 North American patients. Conclusion: Atherosclerotic stenosis of intracranial ICA territory is more common in Iranian than in North American populations.
Gholamreza Sharifirad , Aziz Kamran , Mohammadhasan Entezari ,
Volume 7, Issue 4 (12-2007)
Abstract
Background & Objective: Diabetes is one of diseases in which the main part of treatment depends on the patient's responsibility. Therefore their knowledge of the various aspects of nutrition has great importance. The aim of this study was to evaluate the effect of diabetic diet education on nutritional behaviors. FBS and BMI of patients with type II Diabetes mellitus in Iranian Diabetic Association. Methods: 88 type II diabetic patients from Iranian Diabets Association (Karaj Branch) participated in this study. The Patients were randomly divided into two groups as experimental (44) and control group (44). Data were collected with a valid and reliable questionnaire (58questions) and checklist in two stage of before and one month after intervention. Results: After the intervention in the experimental group regarding diabetes and nutritional behaviors, there was a significant increase in mean score of knowledge (from 57.50 to 80.18) and a significant decrease in the mean of BMI (from 28.3 to 27.9) and in the mean of fasting blood sugar (from 167.9 to 134.5) (p<0.001). However, there was no significant change in the control group. Conclusion: The finding of this study indicated the efficacy of education on FBS and BMI in patients with type II diabetes.
Habib Ojaghi, Rahim Masoumi, Masoumeh Mohammadi,
Volume 8, Issue 1 (4-2008)
Abstract
Background & Objective: one of the most common causes of Epiphora or lacrimation or recurrent infection is Dacryocystitis. The Dacryocystorhinostomy operation, which involves fistulization of the lacrimal sac into the nasal cavity may alleviate the symptoms. Since the routine usage of silicon tube in DCR operation for reducing the replapse has been a controversial issue, This study was done to investigate the rate of success of DCR operation
with silicone tube.
Methods: This study was a cross-sectional descriptive study in which all of the patients (189) who had history of DCR at Sina and Alavi hospitals were asked to continue the treatment after the operation through contact or follow up from home. So the results of their records were analyzed statistically.
Results: 102 out of 189 patients had history of operation who had referred for follow up, in terms of most prevalent symptoms, epiphora and purulent discharge was the highest 55.6% and the second one was epiphora alone 29.1%. The operation prevalence was more in women 74.1%. than in men 25.9% and unilateral involvement 97.3% was more than bilateral one. The highest age prevalence in DCR operation was 30-60 years. The surgery was successful in 82.3%. It was a little more successful in men (85.7%) than in women and the mean age of patients with successful DCR surgery was more than that of patients with unsuccessful DCR surgery.
Conclusion: The results showed that the rate of recovery in unilateral involvement is more than that of bilateral involvement. Also, success after the operation in patients whose primary complain was only purulent discharge was significantly more than those whose primary complain was epiphora and purulent discharge, It also seems that routine application of silicon tuby in DCR surgery has no effect in the increase of recovery and decrease of disease
recurrency which of course more prospective studies are required to prove this.
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