---

 Background & Objectives:�Understanding children’s behavior and its affecting factors is the foundation for practicing dentistry for children effectively and, at the same time instilling a positive dental attitude into them. A number of studies have been done in this regard during the last three decades. This study is another attempt to find out proper strategies in order to control and optimize the diagnostic and trearment measures as well as to investigate the effect of mothers ’ personality characteristics on children ’ s behavior.

 Methods: The sample consisted of 104 randomly selected children (53 boys and 51 girls) at the age of 3 to 6 together with their mothers. The children had no previous dental experiences and no mental or physical disabilities entailing special care. Children’s behavior was assessed during three different dental visits according to Frankle ’ s Behavioral Rating Scale, in which four distinctive scales, namely absolutely negative, negative, positive and absolutely positive were precisely defined and scaled. The first visit was dental examination, the second was fluoride therapy and the last one was restorative dental treatment. Meanwhile, their mothers ’ personalities were determined through an interview conducted by a psychiatrist and based on DSMIV criteria and using General Health Questionnaire (GHQ) these personality characteristics were categorized in four groups: Normal, Depressed, Anxious and Obsessional.

 Results:�The findings revealed that 12.5% of children had no cooperation during 3 visits, most of whom were 3 to 4 years old. The difference was significant compared to 4-5 and 5-6 year old children (p<0.05). In addition, sex did not influence children ’ s behavior. This study showed that children of mothers with obsessional personality were the most cooperative ones during the 3 visits compared to mothers with other personality characteristics. This difference was statistically significant at the first visit, (p<0.05).

  Conclusion: Mother ’ s personality has the strongest effect on children’s behavior during the first dental visit.

---

Background & objectives: Zinc as one of the most important trace elements is needed for proper functioning of the nervous system and homeostasis. Many studies show that stress causes memory impairment through various mechanisms, including oxidative stress induction and some mechanisms which are directly effecting brain function. So, in this work we assessed the effect of zinc chloride on passive avoidance memory and oxidative stress following acute stress in male rats.

Methods: In this study, 50 male Wistar rats were used in five groups: control, sham, stress, zinc chloride treatment and zinc chloride treatment before stress induction. For stress induction, rats were restrained (not immobilized) for 6 h/day, 7 days in a Plexiglas restrainer, and treated rats received an oral dose of zinc chloride 32 mg/kg/day by gavage for 6 days. At the end of the experiment, passive avoidance memory was avaluated by shuttle box and some oxidative damage markers were determined in all groups.

Results: Results of this study showed that animals which were exposed to stress showed a significant decrease in passive avoidance memory compared to control group (p<0.01) and the oxidative stress parameters in this group showed significant changes compared to the control group (p<0.05). While passive avoidance memory and oxidative stress parameters in group treated with zinc chloride were nearly closed to control group.

Conclusion: According to our results, zinc chloride with antioxidant properties can have a protective effect on memory impairment and oxidative stress induced by stress.

---

 
Background & objectives: In recent years, more attention has been paid to the cognitive impairments of children with attention deficit hyperactivity disorder (ADHD) and several studies have been conducted in this field. One of the areas that have been considered in these studies is the defect in executive functions. The aim of this study was to investigate the role of executive functions in differentiation children with intestinal parasitic diseases and ADHD in Karaj city.
Methods: This was a descriptive, cross-sectional study. The statistical population consisted of all children referred to the Radmin Comprehensive Rehabilitation Center of Karaj in 2019. Convenient sampling was performed on 120 children in groups of 40 members, including healthy children, children with ADHD and intestinal parasite infection group. Research tools included diagnostic interview, Conners grading scale, continuous performance test, n-back test and parasitic test. Data were analyzed by SPSS software version 23 using logistic regression and diagnostic analysis.
Results: Findings showed that logistic coefficients of active memory in children with intestinal parasite and active memory and attention retention in children with ADHD were significant. Also, healthy children and children with ADHD (85%) and children with intestinal parasitic disease (52.5%) had the highest accuracy in predicting respectively. based on the proposed model they were correctly classified.
Conclusion: Just as hyperactivity has a pattern of dysfunction performance in executive functions such as working memory and attentional retention, intestinal parasite-related diseases can also have such symptoms. In fact, the symptoms of a child with intestinal parasite are very similar to the symptoms of a person with ADHD, which can lead to errors in assessment and diagnosis.

---

Background & objective: The causes of Alzheimer's disease are currently unknown. Genetic and environmental factors can be effective in creating of this disease. In recent studies, one of the genes and its polymorphisms that was known to affect Alzheimer is SHARPIN. This study aimed to investigate the presence of rs34674752 polymorphism in the SHARPIN gene and its relation with Alzheimer's disease in the population of Iranian patients.
Methods: This study was performed on 50 people with Alzheimer's disease and 50 healthy controls. After blood sampling and DNA extraction, genotyping was done by Tetra ARMS PCR. The data was statistically analyzed.
Results: Results showed that the frequency of GG, GT and TT genotypes of rs34674752 polymorphism in control and patient groups was 100%, 0% and 0%, respectively. Both control and patient groups were in Hardy Weinberg equilibrium. There was no significant correlation between people's genotype and the possibility of Alzheimer's disease, and among the demographic factors, only the relationship between age group and the disease was significant (p=0.029).
Conclusion: According to the results of this study, there was no statistically significant association between the rs34674752 polymorphism in the SHARPIN gene and Alzheimer's disease in the studied Iranian population. To confirm the present study results, the investigation of populations with different societies and a larger quantity of samples are recommended.