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 Lipomas are common benign soft tissue neoplasms but they are found rarely in the parotid gland .

 Surgical intervention in these tumors is challenging because of the proximity of the facial nerve, and thus meticulous surgical techniques are essential. The patient was a 12-year-old female presented with a large asymptomatic mass which had occupied the right facial area. She requested surgical excision for cosmetic reasons. The CT scan defined giant lipoma arising from the right parotid gland. The lipoma was successfully removed after dissecting and preserving of the facial nerve branches. The patient experienced an uneventful recovery, with and intact facial nerve function .

 Lipomas of parotid gland are extremely rare. The high- resolution CT scan provides a prefer method of preoperative diagnosis. Surgical management should be performed by experienced surgeon. Superficial parotidectomy is unnecessary in selected cases of deep lobe lipomas because preservation of superficial lobe may contribute to better cosmetic results .

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  Background & Objective: Advances in public health and control of infectious diseases have led to increased number of elderly people in the world including Iran. Thus serious concerns exist in terms of age-related diseases . Consequently, Iran’s ministry of health has chosen “ageing and health” as the theme for 2012 along with WHO. Psychological disorders�are among the most prevalent diseases in elderly people. Recent studies suggest a two-way relationship between some psychological disorders and insomnia. Also there is evidence implying magnesium role in improvement of aforementioned disorders. The objective of this study was to determine the effects of dietary magnesium supplementation on mental health in insomniac elderly subjects.

  Methods: A double-blind randomized clinical trial was conducted on 46 insomniac elderly subjects randomly allocated into the magnesium or the placebo group, receiving daily for 8 weeks either 500 mg magnesium or a placebo, respectively. SCL-90-R and ISI questionnaires were conducted at baseline and at the end of the intervention period. Serum magnesium and cortisol levels were also determined in the patients. In addition, information was obtained on anthropometric confounding factors and daily intake of magnesium, calcium, potassium and caffeine using 24-hr dietary recall questionnaire for 3 days. The N4 and SPSS19 were used for data analysis.

  Results: No significant differences were observed in assessed variables between the two groups at baseline. As compared to the placebo group, in the experimental group, dietary magnesium supplementation brought about statistically significant decreases in GSI, PST, PSDI, ISI scores as well as somatization , anxiety, psychoticism , and depression symptoms and serum cortisol concentration. While the obsessive-compulsive , interpersonal sensitivity, hostility , phobic anxiety, paranoid ideation scores and serum magnesium concentration were not different between the experimental and the placebo groups.

  Conclusion: In this study dietary magnesium supplementation resulted in improvements in insomnia severity index and some indices of mental health.

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Background & objectives: exposure to lead has a wide range side effects on fertility. Vitamin D is one of the most important vitamins required for the body. This study was conducted to determine the effect of vitamin D on spermatogenesis in male rats treated with lead nitrate.
Methods: In this experimental study, 25 adult male Wistar rats (250-300 gr) were randomly divided into 5 groups (n=5). Control group without any treatment, the group receiving lead by gavage and experimental groups receiving lead plus vitamin D at doses of 25, 50 and 75 mg/kg body weight by gavage  for 28 days. At the end of the study, after anesthetizing the rats, blood samples were collected directly from heart and serum levels of testosterone hormone, Follicle-stimulating Hormone (FSH) andLuteinizing Hormone (LH) were measured. Histological studies were performed to count the spermatocyte and examine the diameter of the seminal tube. Data were analyzed by SPSS software using one-way ANOVA, at significance level of p>0.05.
Results: Compared to the control group,  the mean serum testosterone level in the lead group significantly decreased (p<0.001) and the mean LH and FSH serum levels significantly increased (p<0.001) . Also, spermatocytes and seminiferous tubule diameter significantly decreased (p<0.001). Vitamin D consumption reduced the effects of lead intake, and  this effectiveness was completely dose-dependent.
Conclusion: Our data showed that vitamin D has a significant effect on serum testosterone levels and gonadotropins.

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Background & objectives: The aim of the present study was to investigate the effects of   oral creatine supplementation on biochemical markers of liver, kidney and testis in the male rats under swimming training plan.
Methods: In this study, male Wistar rats, weighing 245±5gr, were divided into five groups (n=8): control, exercise plus zero dose, exercise plus low-dose, exercise plus moderate dose and exercise plus high dose of creatine (200,300 and 600 mg/kg/d respectively). Biochemical studies of blood serum were performed ten days after creatine supplementation and swimming exercises. Following serum collection, the alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN), creatinine and testosterone levels were measured using spectrophotometry method. Statistical analysis was performed by SPSS software using mixed model ANOVA.
Results: serum levels of ALP showed statistically significant differences between groups receiving low and moderate doses of creatine compared to both control and exercise with zero dose  (p<0.05). Also, the results of serum levels of BUN, ALT and AST showed there was no significant difference between the exercise plus zero dose of creatine, exercise plus low-doses of creatine group, exercise plus moderate dose of creatine, exercise plus high dose of creatine groups and control group. The exercise group with high doses of creatine significantly showed a higher serum creatinine level than control group (p<0.05).The serum testosterone level was significantly higher in the exercise with moderate doses of creatine group than in the control group and exercise plus zerecaratin dose (p<0.05).
Conclusion: The results suggested that short-term creatine supplementation (up to 10 days) might adversely affect some biochemical markers of liver, kidney and testis. However, further studies are necessarily needed to clarify the consumption of short-term creatine supplementation.