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Showing 3 results for Shafaei
Fahimeh Sehhatie Shafaei , Fatemeh Ranjbar Koochaksariie, Morteza Ghojazadeh, Zhila Mohamadrezaei, Volume 8, Issue 1 (Spring 2008)
Abstract
Background & Objective: Depression is a debilitating disorder with high prevalence especially in child-bearing women. This study was done to determine relationship between postpartum depression and its various risk factors. Methods: This was a descriptive-analytic study on 600 women referring to health centers in Tabriz. Data were gathered using a questionnaire including 5 parts: demographic characteristics, mother-newborn characteristics, Rosenberg self-esteem scale, Holms stress scale, Edinburgh Postnatal Depression Scale. These data were analyzed by descriptive and inferential statistical methods in SPSS 14/win software. Results: In this study 34.7% of mothers were depressed (scores>12). Significant risk factors for postpartum depression were: Marital dissatisfaction, relationship with mother, mother-in law and husband's family, job dissatisfaction, house condition, having an unpleasant pregnancy experience, unplanned pregnancy, baby care stressors, infant feeding method, nursing problems, mother's self-esteem and stress level. Conclusion: Concerning high prevalence of postpartum depression in this study and other similar studies and effects of some factors in this disorder, it seems to be necessary to improve the knowledge of mothers and health care staff about this risk factors for reducing effects of this disorder on physical and psychological health of newborns, mothers and community.
Mahin Kamali Fard, Raziyeh Alizadeh , Fahimeh Sehati Shafaei , Mortaza Gojazadeh, Volume 10, Issue 1 (spring 2010)
Abstract
Background & Objectives :Prematurity is still one of the main causes of neonatal mortality and morbidity that makes a lot of financial, psychosocial and emotional problems. Although the main cause of preterm labor is unknown but understanding of its risk factors is important for planning health policies for preventing and decreasing the rate of preterm labor. This study aimed to compare lifestyle of women with term and preterm delivery. Methods :This research is a case-control study. Subjects of this study were 132 women with preterm labor and 264 women with term labor that referred to Educational and Medical Center of Alzzahra. The subjects were selected by convenience method and matched in age and educational level. Data were collected by questionnaire containing two sections, demographic characteristics and woman's lifestyle including,nutrition, exercise, smoking and use of alcohol and substance abuse, social support, stress management and self care. Data were analyzed by SPSS with descriptive statistics and statistical tests of t Test, Man Witny U, χ 2 and Fisher's Exact Test. Results : The results of this study showed significant differences in nutrition, smoking, use of alcohol, substance abuse, social support, stress management and self care between two groups, but the mean score of exercise in term and preterm birth was not statistically significant. Conclusion: The findings of our study suggest that there is a relation between lifestyle in pregnancy and preterm birth. Lifestyle is changeable and achieving this aim is possible by efforts to increase health education .
Fateme Askarifar, Ebrahim Shafaei, Mahsa Sedighi, Amir Tavakoli Kareshk, Volume 23, Issue 3 (Autumn 2023)
Abstract
Background: Bacterial infections are a major cause of chronic infections and mortality, and antibiotics are the preferred treatment for bacterial infections. However, studies show that widespread use of antibiotics has led to the emergence of multidrug-resistant bacterial strains. Hence, the need to develop new and alternative strategies for the production of effective drugs has become an important issue. Recently, the use of nanotechnology has been widely common in various fields. Materials in the nanoscale have unique physical and chemical properties. Silver nanoparticles have different applications and their antimicrobial properties have been confirmed in several studies. This study aimed to investigate the antibacterial properties of silver nanoparticles synthesized by berberine and Hypericum perforatum extract.
Methods: In this experimental study, the antibacterial effects of synthesized nanoparticles on standard strains of Escherichia coli [ATCC 25922], Pseudomonas aeruginosa [ATCC 27853], Klebsiella pneumoniae [ATCC 9997], and Staphylococcus aureus [ATCC 29212] were investigated. The MIC content of silver nanoparticles alone and in combination with berberine and Hypericum perforatum extract was investigated for the studied bacteria using the broth microdilution method.
Results: The results of the evaluation of the minimum inhibitory concentration [MIC] of the synthesized compounds on the studied bacteria showed that the nanoparticles synthesized by berberine and Hypericum perforatum extract had the highest antibacterial effects. However, each of the compounds Berberine and Hypericum perforatum extract alone did not show significant antibacterial properties. The results of this study also showed that the highest inhibitory concentration of nanoparticles synthesized by berberine and Hypericum perforatum extract was related to Pseudomonas aeruginosa [0.0375 mg / ml] and the lowest inhibitory concentration was related to Enterococcus faecalis [0.185 mg/ml].
Conclusions: The results of the present study showed that silver nanoparticles synthesized with berberine and Hypericum perforatum extract have significant antibacterial effects. As a result, nanoparticles, including silver nanoparticles, can become one of the most important alternatives to antibiotics due to their unique properties in targeting bacteria. However, achieving definitive results requires further studies in this area.
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