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Showing 3 results for Sedigh
Manoochehr Barak , Leila Azari-Namin , Ali Nemati , Nategh Abbasgholizadeh , Mehrdad Mirzarahimi , Anooshirvan Sedigh ,
Volume 3, Issue 4 (Winter 2003)
Abstract
Background & Objective : Failure To Thrive (FTT) refers to the insufficient physical growth or inability in keeping the desired growth rate in a period to time. It is a problem in Iran as far as hygienic nutrition is concerned. FTT is a multifactor problem which is caused by various organic and nonorganic agents. This study was conducted to pinpoint the major risk factors involved in the growth of children under 2 years of age who are the most vulnerable age-group in terms of growth disorders. Methods: This case-control study was conducted in 2002-2003 on 120 infants (60 cases with FTT and 60 controls) in Namin health centers. The case group was under the third percentage of their growth chart or they had -2SD in growth chart at least in three months. The control group was composed of infants with normal growth chart. The demographic characteristics of parents, and the nutritional and antropometric (height/weight, head circumference) characteristics of the subjects were measured. The collected data were analyzed by SPSS software, using chi-square and ANOVA. Results: The findings indicated higher frequency of respiratory infections, diarrhea and vomiting in case group (p<0.05). The control group, on the other hand, outnumbered the case group in terms of the number of infants under 6 months who were exclusively breast-fed (p<0.05). Most of the infants with FTT had a lower birth weight than control group (p<0.05). The number of mothers with lower level of education and those who were housewives and also the number of family members were significantly higher in case group than control group (p< 0.05). However, no significant difference was observed between two groups in terms of frequency of breast feeding and birth rank. Conclusions : The results indicated that some risk factors such as respiratory infections, birth weight, education, mother ُ s knowledge, exclusive breast feeding and the frequency of diarrhea and vomiting have far more important role in growth disturbances in children compared to factors such as frequency of breasr feeding and birth rank.
Ms Shadi Sabetghadam, Afsaneh Keramat, Mina Malary, Sedighe Rezaie Chamani,
Volume 19, Issue 3 (atumn 2019)
Abstract
Introduction & objectives: Vaginismus is an uncontrolled contraction of the outer third muscle of the vagina that prevents intercourse. Based on the DSM-V-TR system, this disorder is associated with dyspareunia and "Genito-pelvic pain/penetration disorder". The purpose of this overview was to summarize population-based studies that reported the prevalence of vaginismus in the general population and to discover the discrepancies between studies.
Methods: This systematic review study was conducted on published articles on the prevalence of vaginismus in the world and in English. In selecting the articles, the keywords including Vaginismus, Prevalence, Incidence, Sexual Dysfunction, Genito-Pelvic Pain, Penetration Disorder with all possible combinations were systematically searched in the google scholar, science direct, PubMed, Cochrane databases. No search time limit was set to retrieve all relevant articles published by September 21, 2018.
Results: Of the 10 studies, 4 articles reported prevalence of vaginismus in the general population. In selected studies, the incidence of vaginismus in the general population of women was reported 0.4% to 8%.
Conclusion: Different prevalence rates have been reported in different studies for vaginismus. In this review study, it was not possible to Meta-analyze and determines the overall prevalence due to the heterogeneity of the prevalence reports and different study methods.
Fateme Askarifar, Ebrahim Shafaei, Mahsa Sedighi, Amir Tavakoli Kareshk,
Volume 23, Issue 3 (Autumn 2023)
Abstract
Background: Bacterial infections are a major cause of chronic infections and mortality, and antibiotics are the preferred treatment for bacterial infections. However, studies show that widespread use of antibiotics has led to the emergence of multidrug-resistant bacterial strains. Hence, the need to develop new and alternative strategies for the production of effective drugs has become an important issue. Recently, the use of nanotechnology has been widely common in various fields. Materials in the nanoscale have unique physical and chemical properties. Silver nanoparticles have different applications and their antimicrobial properties have been confirmed in several studies. This study aimed to investigate the antibacterial properties of silver nanoparticles synthesized by berberine and Hypericum perforatum extract.
Methods: In this experimental study, the antibacterial effects of synthesized nanoparticles on standard strains of Escherichia coli [ATCC 25922], Pseudomonas aeruginosa [ATCC 27853], Klebsiella pneumoniae [ATCC 9997], and Staphylococcus aureus [ATCC 29212] were investigated. The MIC content of silver nanoparticles alone and in combination with berberine and Hypericum perforatum extract was investigated for the studied bacteria using the broth microdilution method.
Results: The results of the evaluation of the minimum inhibitory concentration [MIC] of the synthesized compounds on the studied bacteria showed that the nanoparticles synthesized by berberine and Hypericum perforatum extract had the highest antibacterial effects. However, each of the compounds Berberine and Hypericum perforatum extract alone did not show significant antibacterial properties. The results of this study also showed that the highest inhibitory concentration of nanoparticles synthesized by berberine and Hypericum perforatum extract was related to Pseudomonas aeruginosa [0.0375 mg / ml] and the lowest inhibitory concentration was related to Enterococcus faecalis [0.185 mg/ml].
Conclusions: The results of the present study showed that silver nanoparticles synthesized with berberine and Hypericum perforatum extract have significant antibacterial effects. As a result, nanoparticles, including silver nanoparticles, can become one of the most important alternatives to antibiotics due to their unique properties in targeting bacteria. However, achieving definitive results requires further studies in this area.
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