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Showing 2 results for Saki
Zahra Fardiazar, Farzane Zahery , Sedige Sadegy Khamene , Sakine Mohammad Alizade , Hosein Kooshavar,
Volume 6, Issue 1 (spring 2006)
Abstract
Background & Objectives: Post-episiotomy perineal pain is one of the most common causes of maternal morbidity and is often poorly treated. This study was performed to investigate effectiveness, side effects and patient satisfaction when lidocaine gel and placebo are used. Methods: In this double-blind clinical trial a total of 124 women who had normal viginal delivery with mediolateral episiotomy without other complications were randomly selected to receive lidocain gel or placebo. Pain intensity was assessed by numerical rating scale (0-10) after perineal pain in different intervals. Pain relief was assessed by number of pain pills, amount of gel used and the degree of painlessness. Repair of episiotomy was assessed by physical examination on 1 and 10 days after delivery. The data were used to fill out a questommaire. Finally, these data were analysed by SPSS ll (rel 11). Results: There was no significant difference in the amount of pain pills taken, the amount of gel used and patients satisfaction between two groups. Regarding the healing of episiotomy there was no significant difference between two groups in the first and tenth day examinations and all wounds healed on 10th day. Satisfaction of the patients regarding the use of gel was the same in two groups. Conclusion: Despite the findings of some similar studies, topical gel of 2% lidocaine was not significantly different from placebo for healing eposiotomy and relieving its pain. But in both groups result of healing on 10 th day postpartum was good. More studies are required to indicate the effect of high dose of lidocaine on pain relief and the positive effects of using gel on wound healing.
Najmaddin Saki, Akbar Dorgalaleh , Zahra Kashani Khatib, Shaban Alizadeh , Fakher Rahim, Hamid Galehdari, Bijan Kaikhaei, Mohammad Pedram , Ali Dehghani Fard ,
Volume 13, Issue 3 (autumn 2013)
Abstract
Background: Co-inheritance of hemoglobin gene defects is a rare important status that can lead to double heterozygote or homozygote with significant clinical manifestations. Such conditions can be observed in co-inheritance of alpha-thalassemia with beta-thalassemia or hemoglobinopathy. The aim of this study was to evaluate the prevalence of alpha-thalassemia with beta-thalassemia and hemoglobinopathy co-inheritance in a considerable number of Iranian. Methods: This descriptive study was performed on patients with abnormal hematological findings in favor of alpha-thalassemia, beta-thalassemia or beta-hemoglobinopathies. Patients with low MCV and MCH levels and high HbA2 (>3.5) and those with low MCV and MCH and normal or low HbA2 were candidate for molecular analysis for beta and alpha thalassemia respectively. Abnormal Hb electrophoresis was diagnostic criteria for molecular analysis of beta-hemoglobinopathies. Results: Study revealed that more than half of the patients with alpha-thalassemia affected simultaneously by beta-thalassemia and about thirty percent inherited beta-hemoglobinopathies. Among patients with beta-thalassemia, HbSCd6 (A-T) was the most common mutation and in alpha-thalassemic patients α 3.7 was the commonest mutation. Conclusion: Relatively high prevalence of co-inheritance of alfa-thalassemia with beta-thalassemia and hemoglobinopathies reflect the necessity of genetic consulting and molecular analysis in diagnosis of such conditions.
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