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Showing 2 results for Rassoli
Masuood Parish, Soosan Rassoli, Mohammad Reza Afhami, Farnaz Moslemi, Volume 5, Issue 2 (Summer 2005)
Abstract
Background & Objectives: Oculocardiac reflex (OCR) is presented with bradycardia and other arrhythmias, is induced by mechanical stimulation and therefore, encountered during strabismus surgery. The aim of this study is to determine the incidence and risk factors of cardiac arrhythmias during strabismus surgery in children and adults. Methods: In this prospective, randomized and double-blind study, 46 patients ASA class I and II underwent elective strabismus surgery with general anesthesia and were allocated to one of the two groups: children under 12 and adults over 12. All patients received standard general anesthesia based on their age. Demographic data, type of involved muscle, the incidence, (type and frequency) and the cause of arrhythmias and skillfulness of the surgeon (professor-assistant) were recorded. Results: There were 26 patients in children group and 20 patients in adult group. The overall incidence of arrhythmias was 91% with 96.15% in children and 85% in adults. There was not any significant difference in the incidence of arrhythmias, and the mean rate of occurence between two groups. Most of the arrhythmias were due to external ocular muscles traction. Conjunctival traction and pressure on the globe were the other causes. Stimulation of median rectus muscle as the most important arrythmogenic factor was seen in 13 children and 12 adults. Bradycardia and tachycardia were among common arrhythmias, but there was no significant difference between two groups (P>0.05) in terms of their incidence. Conclusion: This study showed that the incidence of arrhythmias during strabismus surgery is high in both children and adults. This reflex does not often lead to hemodynamic compromise, however, for its early diagnosis and treatment, close and continuous monitoring of the patient as well as cooperation and communication between anesthesiologist and surgon is needed.
Ghasem Fattahzadehardalani , Masoud Ghasemi , Nasim Tarassoli , Volume 15, Issue 1 (spring 2015)
Abstract
Background & objectives: This study evaluated the effect of intravenous magnesium sulphate on clinical improvement of the patients with acute stroke. There is a lot of information about the use of magnesium sulphate in different conditions of brain ischemia while the effect of magnesium sulphate as a neuroprotective agent has been demonstrated in focal and global brain ischemiain animal models. However, the effect of this agent is still unclear.
Methods: 80 patients (47 % female and 53 % male) with acute ischemic stroke signs and symptoms, lasting less than 12 hours of ischemia, were included in the study. Patients were divided into two groups 40 patients received 4 g of MgSO 4 over 15 minutes and then 16 g over the next 24 hours, and the other 40 patients received serum normal salin as the placebo.
Results: The results showed that magnesium sulphate administrated group had better clinical improvement rate than control group. The number of patients with grade III decreased in magnesium received group and patients with grade II, I were increased. After 2 weeks, patients with Grade IIIdecreased to 12.5% and the patients with grade II and I increased to 50% and 37.5%, respectively(based on NIHSS score).
Conclusion: According to this study,magnesiumsulphatecan be used as a neuroprotective agent in patients with acute stroke.
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