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Showing 4 results for Rahmani
Fariba Sadeghi Movahhed , Parviz Molavi , Farid Gossili , Touraj Rahmani , Firouz Amani , Amir Masoud Rostami ,
Volume 12, Issue 1 (spring 2012)
Abstract
Background & Objectives: Insomnia is one of the most common sleep disorders in the world. It causes disruption in daily activities and increases the risk of major depression. Hence, clinically the appropriate and persistent treatment of insomnia is very important. Using of hypnotic drugs such as benzodiazepines is the common treatment for insomnia but they show several side effects and it seems that new medications should be used for treatment of sleep disorders. The aim of this study was comparison between the effects of electromagnetic therapy and conventional drug usage in the treatment of insomnia. Methods: In a blind randomized clinical trial study, 60 people referred to the private office of the psychiatrist and experienced more than 3 months extended primary insomnia were selected. They were diagnosed by DSM-IV criteria and had no other underlying problems. The subjects were divided in two groups: 30 people in each and treated electromagnetically or with Alprazolam for 3 weeks. Before treatment, immediately and one month after treatment, quality of sleep and severity of the insomnia were evaluated by using the standard questionnaires and finally, the results were analyzed statistically. Results : In this study, 60 individuals participated from whom 28 were male (46.7%) and 32 patients were female (53.3%).The mean age was 37.3 years old in a range of 17- 65. The mean point of each questionnaire, before and immediately after treatment significantly didn't show any difference but one month after treatment, there was a significant difference in both groups. Conclusion : To treat insomnia, electromagnetic therapy appears to be used as a replacement for sedative medicines. It also has more stability in comparison with other sedative medicines and no side effects have been reported yet.
Touraj Rahmani , Farid Bahrpeyma, Manoochehr Iranparvar , Mohammad Taghikhani ,
Volume 14, Issue 3 (Autumn 2014)
Abstract
Background & objectives: Type 2 diabetes mellitus results in vascular dysfunction and reduction of nitric oxide (NO) level. In this study the effect of electromagnetic field (EMF) on NO level, an effective factor in increasing blood flow, and on ankle brachial index (ABI) as a n index of lower extremity blood flow in type 2 diabetic patients, have been investigated. Methods: This study was a randomized controlled clinical trial carried out in Imam Khomeini hospital of Ardabil and Mehr physiotherapy center in 2013. Thirty diabetic patients after initial pilot study participated in this experiment based on inclusion and exclusion criteria. Then, they were randomly assigned into two equal groups, electromagnetic therapy and control. The baseline levels of ABI and NO of both groups were measured. Patients in electromagnetic group were exposed to 10 Hz EMF radiation (with intensity of 8 mT) together with scanning lower limbs (three sessions per week, and 40 minutes per session for 8 weeks). The control group did not receive any treatment. After eight weeks, the amount of ABI and NO level were recorded. For statistical analysis paired t-test and independent t-test were used in SPSS 19 software. Results: Statistical analysis showed significant differences between pre (1.009±0.02) and post (1.052±0.02) measurement of ABI of diabetic patient after applying magnetic field ( P = 0.013). However, there was no significant difference between p and after measurement of ABI and NO level in controlgroup and also NO level in magnet groups ( P> 0.05). Difference between pre and post therapy of ABI in electromagnetic group (0.05±0.01) showed significant increase compared with control group (0.004±0.003) ( P = 0.001). Conclusion: Increase in ABI after 8 weeks electromagnetic therapy could be considered as an accretion index in blood flow in lower extremity.
Abbas Fadaii, Ali Majidpour, Soleymanzadeh Moghadam , Hamideh Rahmani Seraji ,
Volume 18, Issue 4 (winter 2018)
Abstract
Background & objectives: Asthma is one of the most common chronic diseases in the world and Iran. Despite appropriate treatment, recent researches indicate that asthmatic patients have poor asthma control. The aim of this study was to determine the correlation between educational level of asthmatic patients and asthma control indices.
Methods: This retrospective cross-sectional study was performed on 80 asthmatic patients admitted to Shahid Labbafinejad hospital. ESMAA questionnaire was used to collect data to assess the level of asthma control, according to ACT (Asthma Control Test) and 2016 GINA (the Global Initiative for Asthma) guidelines. Patient medication compliance was evaluated based on Morisky medication adherence scale (MMAS). ANOVA test (Regression and Pearson correlation) and Chi-Square test were used for analysis of quantitative and qualitative variables, respectively. The P - value less than 0.05 was considered statistically significant.
Results: Eighty asthmatic patients with an average age of 54.65 were entered to this study that of them 32 patients were at primary school level, 26 patients at high school level and 22 patients at university state. According to ACT test, 52.5% and 47.5% of patients were in control and uncontrolled state, respectively.
According to GINA classification, 30% of patients were in control, 45% in partially control and 25% in uncontrolled state. According to MMSA scale, 20% of patients were high adherent to medicine, 40% were moderate adherent and 40% were low adherent. In this study, there was no significant correlation between the asthma control in terms of ACT and patients' educational level. Also, there was no significant relationship between sex, asthma control and medication adherence. In addition, there was no significant relationship between educational level and drug adherence.
Conclusion: The results suggest that there was no relationship between asthma control indices and patient's educational level. Perhaps other factors, other than education, affect the asthma control indices and medication adherence which requires more studies.
Maryam Zolfali Pourfar , Farhad Rahmani Nia, Parvin Farzanegi,
Volume 21, Issue 4 (winter 2022)
Abstract
Background & objectives: Dynamic disorders of mitochondria cause the pathogenesis of many diseases, such as type 2 diabetes. Therefore, the aim of this study was to investigate the interactive effect of aerobic exercises and atorvastatin consumption on the expression of MFN1/2 and DRP1 in hepatocytes of rat liver with type 2 diabetes.
Methods: In this experimental study, 25 male rats were divided into 5 equal groups: diabetes, healthy control, persistence+diabetes, atorvastatin+diabetes, persistence+atorvastatin+ diabetes. Type 2 diabetes was induced by streptozotocin (STZ) in mice. The training groups performed the running program on the treadmill for eight weeks. Atorvastatin and atorvastatin-exercise groups received atorvastatin (10 mg/kg) by gavage. 48 hours after the last training session, the rats were dissected; their liver tissue was removed and immediately frozen in liquid nitrogen solution at a temperature of minus 80 ° C to measure MFN1/2 and DRP1. One-way analysis of variance and Tukey post hoc test were used for statistical analysis at a significance level of p<0.05.
Results: The results showed that induction of type 2 diabetes decreased the expression of MFN1/2 and increased DRP1 compared to the healthy group. After eight weeks of intervention, a significant increase was observed in the expression level of MFN1 (p<0.05), but this increase was not significant in MFN2 and there was no significant difference in the expression of factors between the groups. Also, after eight weeks, a significant decrease in DRP1 gene expression was observed (p<0.05). This decrease was significant in comparison with the combined groups compared to the patient group.
Conclusion: It is possible that a combination of aerobic exercises and atorvastatin may positively regulate the expression of genes related to mitochondrial dynamics in diabetes.
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