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Showing 2 results for Mosaferi
Mohammad Mosaferi-Ziaaedini, Khosro Ebrahim, Davar Amani, Zahra Arabnarmi, Volume 12, Issue 3 (autumn 2012)
Abstract
Background & Objectives : Intense training increases the production of free radicals and causes inflammatory response in athletes. Strengthen and improving athlete’s immune system may reduce the harmful effects of intense physical activity. The aim of this study was to investigate supplementary consumption of coenzyme Q10 on serum concentration of tumor necrosis factor-alpha (TNF-α) during the maximal activity. Methods : Twelve healthy active males (age 21.75 ± 0.64 yr, BMI 23.7±0.94 kg/m2) performed 30-min exercise at 80% to 85% HRmax. Subjects 120 minutes pre-exercise received either of the following regimens: Coenzyme Q10 (2 mg per kg body weight) or placebo (food color). Blood samples were obtained prior to supplement consumption and immediately after exercise, then groups were reversed after 4 days. The data were analyzed using paired and independent t-test. The statistical significance was set at p<0.05. Results: TNF-α serum level increased in both supplementation and placebo group (4.2% and 5.12% respectively) and the difference between two groups was insignificant. Conclusion : The results of this study indicated that after maximal activity increasing of TNF-α serum level was slower in the supplement group in comparison with placebo group but Q10 consumption did not caused a significant difference between two group (p=0.8).
Maryam Zeraati, Belal Mosaferi, Volume 20, Issue 4 (winter 2021)
Abstract
Background & objectives: Epilepsy is one of the most common problems in the health system, of which some cases are resistant to treatment. Recently, environmental enrichment has shown beneficial results in the recovery of some cases of epilepsy.
Methods: Male mice were reared in an enriched or normal medium during their growth period. To induce seizures, at adult age, each group was divided into two subgroups, which one of them received pentylenetetrazole eleven times, with two days interval.
Results: The enriched environment greatly reduced seizure behaviors and prevented the occurrence of anxiety-like behavior and cognitive disorders. It also prevented an increase in the inflammatory cytokine of TNF-α in the hippocampus.
Conclusion: Therefore, a suitable growth environment in childhood and adolescence can be useful in preventing seizure disorders in adulthood.
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