Backgroud & Objective : Inducing of safe airway and rapid , is very important in the anesthesia of emergency patients and it reduces many complications because of delay in the endotrachal intubation .In this group of patients, administration of succinylcholin is a choice. But, this drug has serious complication, that is sudden increase of serum potassium level , and could cause cardiac arrest .So ,it is suggested, use of non blocker dose of non depolarizant neuromuscular blocker (defasciculation), for reducing this response . So , the aim of this study , was to determine the effect of pretreatment atracurium on serum potassium level associated with administration of succinylcholine .

  Methods: This study was performed clinical trial on 82 elective patients aged between 15 -70 years whit ASAI-II (American society of anesthesiology of physical status class)who where scheduled undergo operate general surgery. Premedication drugs are used to all patients , according to weight. and first blood sample was taken, considered as control group. then pretreatment atracurium injection (50mcg/kg) and after three minutes, was performed induction with thiopental sodium (5mg/kg) and succinylcholine (1.5 mg/kg ), and after 5 minutes , second blood sample was taken, test group . blood samples, were poured in the espicial tube of serum potassium and immediately , serums were separated . Then , potasiom level of serums were measured with micro light . The datas analyzed with statistical program ( spss) and then , were compared .

  Results: According to the obtained results , the mean of serum potassium level after administration of succinylcholine associated with defasciculation atracurium and before the administration of pretreatment atracurium (base level) was not different . It was not seen , a statistically significant difference between two groups, with attention to paired- t-test(p=0.936) and wilcoxon signed ranks test (p=0.594).

  Conclusion: Regarding the results of this study , administration of pretreatment atracurium is not effective in prevention of hyperkalemia induced by succinylcholin with attention base level.

Background & objectives: Surgery of upper part of femor in elderly patients can be due to the fracture of femoral neck, shaft and arthroplasty. Hemodynamic changes and complications of the anesthesia are among the major concerns. The aim of this study was to compare the hemodynamic changes in low dose isoflurane with propofol in upper femoral surgeries in elderly patients.

Methods: This prospective clinical trial study was done on 60 patients over 65 year-old elderly patients with ASA physical status of I and II that were candidate for upper femoral surgery in two groups (inhalational: isoflurane 0.5-0.6 MAC) and (total intravenous anesthesia with propofol 50-100 mic/kg/min). Hemodynamic changes were compared in these groups with the same anesthetic depth (HR-SBP-DBP-MBP-SaO₂).

Results: There was no significant difference in heart rate, age or sex between two groups. In isoflurane group SBP on 20 and 25^th minutes and DBP and MBP on 20, 25 and 35^th minutes were significantly higher than propofol group. In propofol group SaO₂ was significantly more than isoflurane group on induction, start of surgery and on 5, 25, 35 and 45^th minutes of surgery.

Conclusion: In anesthesia with the same Bi-Spectral Index, isoflurane provides more stable hemodynamic parameters than propofol.