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Showing 5 results for Mohajeri

Mahdi Chinifroush, Seraj Mohajeri, Babak Shirinzadeh,
Volume 8, Issue 3 (Autumn 2008)
Abstract

Background & Objectives: Carcinoid tumor is the most common appendix tumor and its origin in from neuroendocrine cells. 80% of tumors are located in GI tract and the most common site of the tumor is appendix .This neoplasm is found in 0.3-0.5 percent of appendectomized samples. The mean age in diagnosis time is 30 years old and the neoplasm is more common in women. The aim of this study was to investigate the age and sex prevalence of carcinoid tumor in appendectomized patients.
Methods: This descriptive study was done on 5644 specimens in the Fatemi Hospital of Ardabil  for surveying of carcinoid tumor prevalence, on the basis of age & sex, from 2003-2007.
Results: In this study, the prevalence of carcinoid tumor was 0.19%, average involvement mean 33.6 years old (ST= 23.1) & the men diameter of tumor was 0.74 cm (ST= 0.37). The prevalence in women was 3 in 1000 and in men was 1.36 in 1000.All of the tumor located in the tail portion of appendix. The tumor can cause acute appendicitis by duct obstruction but mostly is discovered during pathologic examination accidentally, conclusion pathologic examination of appendix with sagital incision in all appendectomy cases is recommended.
Parviz Mohajeri , Babak Izadi , Mansour Rezai , Badie Falahi , Hosna Khademi , Roya Ebrahimi ,
Volume 11, Issue 1 (spring 2011)
Abstract

  Background & Objectives: Nowadays, appearance of ESBL producing bacteria is medical problem in the treatment of infections. Uropathogenic Escherichia coli like many other bacteria can produce these types of enzymes. T he assessment of the ESBL production by clinical isolates is not done routinely in laboratories. The aim of this study was to determine the prevalence of ESBL producing E.coli and its antibiotic resistance pattern in Kermanshah.

  Methods: This cross - sectional study was done on 200 Uropathogenic E. coli strains isolated from people in Kermanshah. Sensitivity of isolates to different antibiotics was determined by disk diffusion test and ESBL production was assessed by DDST method.

  Results: The E. coli strains showed high susceptibility to imipenem (100%), amikacin (97%), nitrofurantoin (95.5%), gentamicin (85%), cefepime (75%), ceftazidime (74%), ofloxacin (73.5%), ciprofloxacin, ceftriaxone and aztreonam (71%) and cefotaxime (70%) respectively. The highest resistance was seen to ampicillin (77%), carbenicillin (76%), pipracillin (74%) and SXT (62.5% ). Resistance rate to third generation cephalosporins was 63-75%. Fifty seven isolates (27%) were ESBL producers and 47 isolates (87%) produced all four types of ESBL enzymes.

  Conclusion: There are some similarities and differences in the antibiotic resistance pattern and ESBL production among the isolates in different areas of Iran and other countries. Identification of ESBL producing bacteria and determining its antimicrobial resistance pattern are recommended to effective treatment of infections.


Darioush Mohajeri , Ali Rezaie , Ghafour Mousavi, Mohammad Mazani, Adel Rezaei-Moghadam,
Volume 12, Issue 2 (summer 2012)
Abstract

  Background & Objectives: The aim of the present study was to evaluate the protective effects of Crocin on rat high fat diet-induced hepatic steatosis model.

  Methods: For this purpose, male rats were given either standard diet as control, high fat diet for induction of hepatic steatosis and high fat diet plus Crocin through gavage at different doses (25, 50 and 100 mg kg-1/day) for protection of liver steatosis, at a period of 4 weeks in different experimental groups and compared considering serum lipid profile, serum biomarkers of liver tissue injury, hepatic antioxidant activity and liver histopathological changes. The serum levels of triglyceride, total cholesterol, low-density lipoprotein, very low-density lipoprotein, high-density lipoprotein for determination of deleterious metabolic effects, alanine aminotransferase, aspartate aminotransferase for determination of hepatocyte injury, alkaline phosphatase, bilirubin for assessment of biliary function, malondialdehyde and reduced glutathione content for assessment of liver free radical activity, the enzymatic activities of glutathione peroxidase, superoxide dismutase and catalase as indicators of antioxidation in liver tissue, were measured. Finally, the biochemical findings were matched with histopathological verifications.

  Results: After 4 weeks, high fat diet caused deleterious metabolic effects, including hypertriglyceridemia, hypercholesterolemia and liver dysfunction. Rats fed high fat diet alone showed increased activities of hepatocellular enzymes in plasma, significant decline in antioxidants, and elevated lipid peroxidation indices in liver. Crocin treatment significantly reduced elevated markers of liver tissue injury and malondialdehyde , and brought back the liver antioxidants and the over accumulation lipids in serum towards normal. Histopathology of the liver confirmed the changes induced by high fat diet and the heptoprotective effect of Crocin.

  Conclusions: Crocin exerts protective effects against hepatic steatosis in rats fed with high fat diet possibly through its antioxidant actions.


Fatemeh Ghannadiasl, Mahsa Mohajeri, Neda Hoseini,
Volume 20, Issue 4 (winter 2021)
Abstract

 
Background & objectives: Considering the high prevalence of body image dissatisfaction and its consequences, it is necessary to consider effective interventions to reduce it. The aim of this study was to investigate the effect of a balanced low calorie diet (BLCD) and slight weight loss on the body image score and its subscales.
Methods: In this clinical trial, 74 apparently healthy, non-pregnant, non-lactating and non-menopausal women (age range: 18-49 years with body mass index range: 27.5-40 kg/m2) were selected using random sampling method from a nutrition clinic in their first visit in Ardabil city between November 2019 and February 2020. Data collection was done by Anthropometric measurements and multidimensional body self-relations questionnaire. The paired T-test was used to compare the changes during 4 - week balanced low calorie diet intervention. BLCD was an individualized diet with an energy deficit of 500 calories of daily energy intake that was calculated from 3-day food records for every person.
Results: After 4 weeks, BLCD resulted in a significant decrease in body weight (p=0.001), body mass index (p=0.001), waist circumference (p=0.002), waist to height ratio (p=0.012), abdominal volume index (p=0.009) and conicity index (p=0.045) and a significant increase in the subscale scores of fitness evaluation (p=0.01), health orientation (p=0.03), body area satisfaction (p=0.01) and overweight preoccupation (p=0.001).
Conclusion: According to the results, it seems that even slight weight loss with a balanced low-calorie diet can be effective in improving anthropometric indices and some subscales of body image in 4 weeks. These results support the effectiveness of short-term interventions.
Shafagh Aliasgarzadeh, Sevda Mikaeili Mirak, Javad Aliasgarzadeh, Hamed Aghazadeh, Seraj Mohajeri, Nima Javanshir, Mohammad Negaresh,
Volume 23, Issue 3 (Autumn 2023)
Abstract

Background: Diabetes is a significant risk factor for postoperative complications and mortality. However, there are different opinions about the relationship between the increase in glycosylated hemoglobin (HbA1c) level and the incidence of surgical complications.
Methods: In this retrospective study, 189 diabetic patients referred to Sabalan Hospital in Ardabil who were admitted for surgery were examined in 2021. The data related to demographic information, HbA1c test, postoperative complications, and the outcome of patients’ hospitalization were extracted from the records and entered into the researcher-made checklist. Patients were divided into two groups of uncontrolled diabetes with HbA1c of 7 and above and the controlled diabetes group with HbA1c below 7.
Results: Out of 189 patients included in the study, 97 patients were in the uncontrolled diabetes group, and 92 patients were in the controlled diabetes group. The average age of diabetic patients in uncontrolled and controlled diabetes groups was 58.18±8.91 and 61.84±5.52, respectively. According to the results, surgical site infection and the need for re-surgery during hospitalization showed a significant relationship with an HbA1c level (p0.05). Other postoperative complications were not significantly different between the two groups.
Conclusion: It seems logical that elective surgeries should be postponed in HbA1c levels higher than 7% because the presence of high HbA1c levels indicates that the patient’s diabetes is not under control, and as a result, there is a higher probability of chronic complications of diabetes as well as a higher risk for post-operative complications.

 

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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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