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Background & objectives: Most of coronary angiography patients have not enough information about undergoing procedure . This lack of knowledge makes anxiety in patients and thereby changes their vital signs. There is no study regarding the effective education of patients based on their native language. This study was done to investigate the effect of video education in native language on vital signs caused by anxiety of patients undergoing coronary angiography.

Methods: This quasi experimental study was done in 2013 on 160 patients undergoing angiography in Imam Khomeini Hospital in Ardabil. Participants were divided into two groups randomly (80 in each group): case (native video education) and control groups. The sheets of hemodynamic variables were completed in determined time intervals for data collection. ANOVA with repeated measures and Chi square were used to analyze the data in SPSS13 software. P-value<0.05 was considered statistically significant.

Results: The results of repeated measures ANOVA showed significant improvement in vital sign variables except for temperature in both groups over the time (p<0.05). And there was significant difference in the mean vital sign variables in determined time intervals (p<0.05).

Conclusion: Video education in native language decreases the vital signs in coronary angiography patients. Therefore the video education especially in native language is recommended for improving vital signs before invasive procedures.

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Background & objectives: cardiovascular diseases are the main cause of mortality around the whole world. However, there is limited information on its economic costs in Iran. The aim of this study was to evaluate the economic costs of coronary heart disease in Iran in 2014.
Methods: The diseases costs were calculated based on the incidence approach using a bottom-up method and a community-oriented perspective.   The drug cost information was obtained from angiographed patients (607 cases) in Shahid Modarres Hospital using simple random sampling method. Other information like disease incidence, distribution of patients, treatment patterns, length of stay and mortality rate was gathered from the literature, interview with patients, consultation with specialists, questionnaire, ministry of health and statistical center of Iran.
Results: Coronary heart diseases impose a significant economic burden in the range of 4,715 and 4,908 billion dollars (210,037,860,000,000-201,778,425,000,000 rials) upon Iran economic system. The medical costs and the costs of lost productivity due to premature death were calculated at USD 3.572 billion (152,863,740,000,000 rials) and USD 933 million (39,927,735,000,000 rials) respectively. The major part of medical costs was related to angioplasty costs (47%) and the minor part was related to drug costs (1.15%).
Conclusion: Coronary heart diseases impose a lot of financial costs to Iran healthcare system which cover more than 16% of whole healthcare financial costs. It is possible to streamline all consequential costs due to coronary heart disease by means of economic and effective use of resources and widespread self-care plan.
 

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Introduction & objectives: Cannabis extract is an important psychoactive substance that have used by people around the world. Due to the diverse effects of cannabis on brain cells, this study was conducted to investigate the effect of cannabis extract on the growth of SH-SY5Y neurons.
Methods: In this experimental study, SH-SY5Y cells were prepared from Pasteur Institute of Iran and then incubated in DMEM, supplemented with  10% fetal bovine serum ,embryo-L glutamine, penicillin and streptomycin at 37^oC and 5% CO₂. following cell proliferation, the cells in the fourth passage were divided into control and experimental groups which were treated with cannabis at concentrations of 100 and1000 ng/ml. during  1 to 9 days, SH-SY5Y cells growth was calculated by flow cytometry using PDT= T× formula.
 
Results: SH-SY5Y cells adhered to the bottom of the flask 24 hours after transfer to the cell culture flask. These cells were initially spherical and after 24 hours become spindle. The results of cell count test on days 1 to 6 showed the growth of cannabis-treated cells similar to the control group, but from the sixth day, in the cannabis extract treated groups, a significant reduction in cell growth was observed at the level of p<0.05 compared to the control group.
Conclusion: The results showed that SH-SY5Y cells in the culture medium were spherically shaped, similar to fibroblast cells, and the based on the results of cell count, it was determined that cannabis inhibits the growth of these cells.