---

  Background & Objectives: The diagnosis�of Helicobacter pylori infection is based on invasive and non-invasive methods. The present study was carried out to evaluate the accuracy of three non-invasive and one invasive methods either separately or in combination for detection of Helicobacter pylori.

  Methods: A total of 108 dyspeptic patients older than 12 years who had not previously been treated for H. pylori infection were selected for upper GI-endoscopy. Histology was considered as a gold standard diagnostic test. Urea breath test, histologic examination and rapid urease test were done in endoscopy unit. Serology and stool anigen detection test were done in hematology unit of Nour Laboratory using ELISA Method.

  Sensitivity, specificity, positive and negative predictive values were calculated. The tests results were compared using the McNemar test.

  Results: According to histologic method, 56 patients had H. pylori infection. Sensitivities and specificities were 89% and 71% for the rapid urease test, 94% and 52% for serology, 90% and 82% for the urea breath test, and 46% and 80% for the stool test respectively. The most accurate combination test was rapid urease test and urea breath test.

  Conclusion: Rapid urease test and urea breath test in combination showed excellent diagnostic reliability.

---

Background & objectives: Considering the importance of prevalence studies in disease management, this study was conducted to determine the prevalence of psychiatric disorders in children and adolescents in Ardabil province.
Methods: In this study, 1035 children and adolescents aged 6 to 18 were selected using cluster random sampling and examined with a digital version of the K-SADS in terms of psychiatric disorders. In the present work, 24 types of psychiatric disorders in children and adolescents were evaluated.  Sampling was done in the general population and interviews were conducted at the door of the house. Assessments were carried out by experienced psychologists. The point and interval prevalence (with 95% confidence interval) were calculated for disorders. Data were analyzed using SPSS ( v.22) software. 
Results: Hyperactivity, oppositional defiant, enuresis, and separation anxiety disorders had the highest prevalence in the studied sample. In contrast, psychosis, autism and panic disorders had the lowest prevalence. Depression had a moderate prevalence (1.7%) among other disorders. The overall prevalence of disturbances was 31.7%.
Conclusion: The prevalence of psychiatric disorders in Ardabil children and adolescents was high. According to this rate, etiologic studies are necessarily needed  for disorders  with  have high prevalence and health systems should design and manage  preventive plans for the general public.