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Background & Objective: Many factors interfere in liver fibrosis one of which is hepatitis B.The aim of our study was to determine the parameters serum iron, TIBC and ferritin of patients with hepatitis B and fibrosis of the liver

Methods: Study involved 50 cases with liver fibrosis and viral hepatitis type B (2002-2004)
and 26 controls. Iron concentration, Total iron-binding capacity and Ferritin concentration were measured by standard biochemical methods. To compare the results of the two groyps a student t-test was used and considering p< 0.05 the difference between two groups was significant.

Results: The results showed that serum ferritin increase 243.7±16.7 micro gr/L and 238.7±13.9 micro gr/L in man and women patients with chronic hepatitis B virus infection compared to the control group, 198.5±14.3 and 182.7 ±14.3 mg/L in man and women, respectively. No significant difference was found between serum Iron and TIBC in both groups. there was a significant relationship between them.

Conclusion: Increased serum ferritin concentration and liver fibrosis induced by hepatitis B virus infection. Also, determination of serum ferritin could help in diagnosis of liver fibrosis.

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  Background & Objectives: Mastalgia is a common breast disorder affecting lots of women during reproductive ages and leads to cancer phobia in some women. It increase clinical referring and disturb the social activities and familial communities. The aim of this study was to determine the clinical, sonogarphical and mammographic findings in patient with mastalgia.

  Method: This cross-sectional study was done on 160 patients with mastalgia who referred to gynecologic clinic, Yahyanejad hospital, Babol University of medical sciences. They were examined by gynecologist, then in patients under 35 years sonography and older than 35 years mammography was done. Other information including age, menarche age, age of first pregnancy, number of delivery, history of oral contraceptive usage or hormone replacement therapy, family history of cancer, knowledge of diet recommendation for mastalgia and correlation of mastalgia with menstrual cycle were recorded for all patients. Data were analyzed using SPSS10.

  Results: The mean age of patients was 34.8±9.9. Tenderness was observed in 122 (76.3%) patients. Fibrocystic disease was seen in 42 (53.2%) patients in mammography and 50 (40.3%) in sonography. There were normal findings in 29 patients (36.7%) in mammography and 60 patients (48.4%) in sonography.

Conclusion: In the majority of women with mastalgia, sonography and mammography showed normal or fibrocystic changes. A comprehensive history and breast exam is essential to make decision.