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Showing 2 results for Hosseininia

Iraj Feizi, Somaieh Matin, Hasan Ghobadi, Saeed Hosseininia, Susan Mohammadi Kebar, Farideh Feizi, Hossein Salehzade,
Volume 19, Issue 3 (atumn 2019)
Abstract

 
Background & objectives:  Hydatid cyst is a major hygiene problem in Iran. In 80% of cases, only one organ is involved. However, multiorgan involvement has also been rarely reported. But it seems, the prevalence of hydatid cyst with the involvement of more than one organ in Iran is more than other world. The aim of this study was to evaluate the patients with hydatid cyst multi organ involvement in Ardabil province in northwest of Iran.
Methods: In this retrospective study, 34 patients with hydatid cyst with involvement in more than one organ were included. For each patient, a pre-designed questionnaire including name, age, education level, occupation, place of residence, cyst location, clinical manifestations and serologic test results were completed. Patients, who had previously a history of treatment due to hydatid cyst, were excluded from the study.
Results: The mean age of patients was 36.41 years. 61.8% of the patients were housewives and 64% were rural residents. The most commonly involved organs was liver and simultaneous involvement of liver and lung was observed in 38.2% of patients and was more in women. The association of the right lung cyst with the liver cysts was greater than that of the left lung. Only in 43% of the patients, the serologic test was positive for hydatid cyst, and the relationship between serologic test and type of involvement was not significant.
Conclusion: Regarding the high incidence of hydatid cyst involvement in more than one location in our region, in all patients, especially women with liver hydatid cyst, other organs, especially the lungs, should be investigated
 
Mohammad Amani, Ali Hosseininia, Hamid Sheikhkanloui Milan,
Volume 23, Issue 1 (Spring 2023)
Abstract

Background & objectives: Parkinson’s disease is a disorder that causes progressive degeneration of neurons, and oxidative stress is increasingly implicated as a factor that contributes to its pathophysiology. Carnosic acid, a compound found in rosemary, can scavenge free radicals in the brain and decrease the risk of neurodegenerative diseases such as Alzheimer’s. Thus, this study explored the effect of this plant on the improvement of Parkinson’s disease.
Methods: The study used 35 male mice that were randomly divided into five groups (n=7 mice each). A control group, a Parkinson's group induced by MPTP toxin, and three groups that received aqueous extracts of rosemary at doses of 100, 150 and 200 mg/kg were included in the study. Measurements were made of lipid peroxidation, superoxide dismutase activity, muscle rigidity, and grip strength. Scores were calculated based on rotational behavior tests and scoring systems.
Results: Rosemary treatment at doses of 150 and 200 mg/kg significantly changed the level of superoxide dismutase activity, muscle rigidity test and rotational behavior of animals relative to the MPTP group. Moreover, the dose of 200 mg/kg of rosemary significantly modified lipid peroxidation relative to the MPTP group, although lipid peroxidation was still significantly higher than the control group.
Conclusion: This study demonstrated that the aqueous extract of Rosemary at a dose of 200 mg/kg can alleviate the signs of Parkinson’s disease and manage the disease.
 

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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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