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Showing 19 results for Farid
Adalat Hosseinian , Seyedhashem Sezavar , Mohammadtaghi Nikneghad , Farid Ghosseili, Zahra Mussavi , Eilnaz Mohammadi ,
Volume 3, Issue 2 (Summer 2003)
Abstract
Background & Objective: Despite all improvements in diagnosis and treatment, one third of patients with Myocardial infarction lose their life. Different studies have shown that cardiac arrhythmia are the most common cause of death in MI, and cardiac blocks are one of the important groups of these arrhythmia, which are effective in prognosis, duration of hospitalization and hospital mortality of the patients. Methods : In this study, 630 patients with AMI, who were admitted in CCU of Bou-Ali hospital in Ardabil from January 1998 to January 2001 were studied and the data were callected with the help of questionnaires and secondary data analysis method. The data were analyzed with statistical methods. Results : 9.4% of cases in this study had AV block and 30.2% had bundle branch block. 40.5% of men and 37.6% of women had at least one kind of block(in AV node or bundle branch), but no significant relation was found between sex and these blocks. Also, 62% of in-hospital mortalities of patients with AMI were in association with blocks (AV or bundle branch) and only 38% of mortalities were without blocks. This showed a meaningful relation between hospital mortality and these kinds of blocks (p <0.05 ). Conclusions: The total frequency of AV and bundle branch blocks due to AMI, was 39.6% which is similar to other studies, but what is remarkable in this study, is the higher prevalence of bundle branch blocks due to AMI.
Saeid Mahmood Tabatabaei, Hosein Nematollahi, Faride Shakeri Manesh ,
Volume 5, Issue 1 (spring 2005)
Abstract
Background & Objectives:Understanding children’s behavior and its affecting factors is the foundation for practicing dentistry for children effectively and, at the same time instilling a positive dental attitude into them. A number of studies have been done in this regard during the last three decades. This study is another attempt to find out proper strategies in order to control and optimize the diagnostic and trearment measures as well as to investigate the effect of mothers ’ personality characteristics on children ’ s behavior. Methods: The sample consisted of 104 randomly selected children (53 boys and 51 girls) at the age of 3 to 6 together with their mothers. The children had no previous dental experiences and no mental or physical disabilities entailing special care. Children’s behavior was assessed during three different dental visits according to Frankle ’ s Behavioral Rating Scale, in which four distinctive scales, namely absolutely negative, negative, positive and absolutely positive were precisely defined and scaled. The first visit was dental examination, the second was fluoride therapy and the last one was restorative dental treatment. Meanwhile, their mothers ’ personalities were determined through an interview conducted by a psychiatrist and based on DSMIV criteria and using General Health Questionnaire (GHQ) these personality characteristics were categorized in four groups: Normal, Depressed, Anxious and Obsessional. Results:The findings revealed that 12.5% of children had no cooperation during 3 visits, most of whom were 3 to 4 years old. The difference was significant compared to 4-5 and 5-6 year old children (p<0.05). In addition, sex did not influence children ’ s behavior. This study showed that children of mothers with obsessional personality were the most cooperative ones during the 3 visits compared to mothers with other personality characteristics. This difference was statistically significant at the first visit, (p<0.05). Conclusion: Mother ’ s personality has the strongest effect on children’s behavior during the first dental visit.
Fariba Kahnamouei Aghdam , Farnaz Ehdayivand, Faride Mostafazadeh, Godrat Akhavan Akbary , Mohammad Sadeghi,
Volume 5, Issue 3 (Autumn 2005)
Abstract
Background & Objectives: Respiatory Distress Synderome (RDS) is one of the major risks of elective cesarian section whose negative health and econemical outcomes are obvious. Maternal prophylactic injection of corticosteroid drugs can reduce RDS of neonate to some extent. On the other hand corticosteroid drugs have some side effects such as delay in the healing of the incision. This study considered the effect of betamethasone on surgical incision. Methods: This study was conducted on 60 primipara women divied into two equal groups that were candidate for elective cesarean. We injected betamethasone (IM) to trial group twice 48 hours poior to operation, (every 24 hours) and complication of surgical incision was clinically evaluated within 7 days after operation in both groups. The data were collected and analyzed by SPSS software chi-square and Fisher tests. Results: Most patients (60%) were 20-30 years old and the average age in both groups was 21. The relative frequency of patients with complication of surgical incision in trial group (betamethasone recipients) was 30% and in control group was 23.33% (the difference between them was not statistically significant). The most common complications were erythema and hyperemia. Other complications observed in 15% of the patients included serousal discharge, local warmness and enduration. Rgarding these complications also there wasn’t a statistically significant difference between two groups. Conclusion: Betamethasone does not increase early onest complications of surgical incision and we can safely use betamethasone prophylactically for fetal maturion in elective cesareans.
Hasan Edalatkhah, Faride Golforoshan, Hamide Azimi, Parviz Mohammadi, Ahad Razi,
Volume 6, Issue 1 (spring 2006)
Abstract
Background & Objectives: In spite of extensive advances in diagnosis and treatment of cutaneous diseases, cutaneous fungal infections are still one of the important reasons to refer to dermatology centers. Incidence of dermatophytosis species is different in various regions. Recognition of these agents has important role in its treatment and eradication. The aim of this study was to determine the various species of dermatophytes in patients referring to Haft-e-Tir Hospital, Tabriz. Methods: This descriptive-analytical study was done on 518 patients referring to Haft-e-Tir hospital from 1997 until 1998. Direct examination in their cutaneous and nail lesions was positive for dermatophytosis. All the samples from their lesions were cultured in special culture media including dextrose agar and sabouraud's dextrose agar plus chloramphenicol and cyclohexamide. The collected data were analysed by SPSS software. Results: There were positive cultures in 70.3% of the cases. Trichophyton verrucosom was the most common agent in all of cutaneous and nail infections. Involvement was more common among the subjects under 15 as well as among males and villagers. Tinea corporis was the most common clinical form of the disease. Conclusion: The findings indicated that zeophilic species and anthropophilic respectively are the most common dermatophytosis species in the region under study. Culture was positive only in 3/4 of the samples.
Faride Golfooroshan, Effat Khodaeiani , Shahla Babaei Nejad , Delara Laghosi,
Volume 6, Issue 2 (Summer 2006)
Abstract
Background & Objectives: Diabetes mellitus (DM) is a clinically and genitically heterogeneous group of disorders characterized by abnormally high levels of glucose in blood. The skin is involved both in the effects of acute metabolic changes and in the chronic degenerative compilications of diabetes. Skin lesions are frequently observed in diabetic patients and it is generally stated that about 30% of these patients have cutaneous disorders. The aim of this study was to assess the prevalence of skin lesion in patients with diabetes mellitus referring to dermatology and diabetes clinic of Sina hospital in Tabriz . Methods: This descriptive-analytical study was conducted on diabetic patients with skin lesion who referr e d to diabetic and dermatology clinic of Sina hospital of Tabriz during 2003. Data collecting instrument was a questionnaire which included some variables such as age, sex, job, type of diabetes, its duration, control of blood glucose, receiving regular treatment, type of lesion. The questionnaire was filled out for each patient with skin lesion individally. Skin lesions due to burn were excluded from our study. The data were analyzed by SPSS using Chi-aquare and Fisher test. Results : From a total of 500 patients, 80 patients (16%) had skin lesions. 57.5% of these patients was male and 91.2% had type II DM. Mean age of the patients with skin lesion was 56.86±1.54 years and mean diabetes duration was 10.87±0.82 years. Patients over 50 years had the most skin lesion . The most common type of skin lesion in the diabetic patients were 30 cases of necrotic ulcer (6%) and 22 cases of diabetic dermopathy (4.4%) respectively. Other skin lesions such as infection, sclerodermoid, punched out lesions, neuropathic ulcer, diabetic bulla, dermatitis and lichen planus were not common . 97.5% of diabetic patients with skin lesion had poor control of blood glucose. Twelve percent of the patients had some kind of diabetic foot ulcer (Neuropathic Necrotic, punched out and cellulitis ulcer altogether) of which 21.6% underwent amputation. Conclusion: The results showed that rate of skin lesions in diabetic patients is decreased. compared to the past. This may be due to increase of knowledge and attitude of patients regarding diabetes and its complications.
Farideh Mostafazadeh , Mehrnaz Mashoufi , Masoumeh Rostamnegad ,
Volume 6, Issue 4 (Winter 2006)
Abstract
Background & Objectives: Ceasarean section (CS) has increased in rate during the past years. Due to postoperative complications, long recovery time and high costs of surgery, normal delivery is recommended as a routine method. Regarding the increase in the number of CS and its acceptability on the part of the public, it seems that women’s as well as health personnels' attitudes play an effective role in selecting the termination method. The aim of this study was to evaluate and compare pregnant women’s and health personnels' attitude toward termination procedures. Methods: This was a descriptive and comparative study. 84 health personnels and 300 pregnant women who referred to Ardabil health centers in 2002 were selected. These subjects' attitudes were collected through Likert questionnaire and the collected data were analyzed by SPSS, using t-test. Results: The findings showed that 30.1% of women and 50% of health personnels had positive attitudes towards normal delivery. The findings also indicated that there was a significant difference between pregnant women and health personnels in their attitudes toward normal delivery and cesarean (p=0.001). Conclusions: Since health personnels had a more positive attitude towards normal delivery than pregnant women did, it seems that the young as well as the pregnant individuals in society need more education and awareness to be able to change their attitudes towards delivery methods. Health personnel, due to their high positive attitude towards normal delivery, can play a more beneficial role in this regard.
Fariba Kahnamouei, Mohammadali Mohammadi, Farideh Mostafazadeh, Afshar Ebrahimi,
Volume 7, Issue 2 (Summer 2007)
Abstract
Backgrond & Objectives: Oligohydramnios is a disorder which is followed by unpleasant outcomes for fetus that can lead to termination of pregnancy before term and preterm delivery. For these patients' increase in gestational period and prevention of preterm delivery is the most important act. In this study the effect of intravenous and oral hydration therapy in increasing duration of gestation in patient with oligohydramnios was evaluated. Methods: In this study, the population was devided into two case and control groups with 30 female individual who were found to have oligohydramnios in course of hospital admission according to on sonographic results. Patients were randomly put in case or control groups. Case group were given 3-4 liter normal salin for 1 week and then were given oral hydration solution until the end of pregnancy, In each group whenever it was found that pregnancy was not possible the pregnancy continuance was stopped. Data collection was through history, physical examination completing relevant questionnaire and findings of sonography and in order to see the relationship among finding s, kitest and t-test from SPSS software were used. Results: The age means of case and control groups were 25 and 24 respectively. The mean of pregnancy duration from the diagnosis time in case group was 30.2 weeks and in control group 31.8 weeks. The mean of pregnancy terminatior in case group was 34.6 weeks and in control group 34.2. In increasing duration of pregnancy in case and control group. It was concluded that intravenous and oral Hydration therapy cause incerease in duration of pregnancy in patients suffering from oligo Hydraminos. According to the results of this study and significance of the difference.
Fariba Sadeghi Movahhed , Farideh Mostafazadeh, Mehrnaz Mashoufi ,
Volume 7, Issue 4 (Winter 2007)
Abstract
Background & Objective: Obsessive-compulsive disorder is a common disease in psychiatry which increases anxiety in approximately 2% of the world population. Recent reports suggest that OCD starts in menstruation, Pregnancy, post-partum periods which causes failure in women's quality of life. The aim of study was to determine the onset of (OCD) in fertile women. Methods: In a descriptive study in 2006, 53 women with DSM-IV were interviewed for obsessive disorder at psychiatry clinic of Fatemi hospital. A questionnaire including two parts on demographic information and 8 questions on the onset of obsessive disorder in menstruation, pregnancy, puerperium periods was completed. Data were analyzed through SPSS. Results: In 3.8%, the onset of obsessive disorder was with the first menstruation period. In 12.5% it was during pregnancy. In 57.1% (4) of obsessive samples onset of obsessive was in second pregnancy. In 16.24% onset of OCD was after delivery. In 28.8% it was after first delivery and 30% after first delivery had affective disorders. Conclusion: The menstruation, pregnancy, post partum may be a periods of risk for recurrence or onset of obsessive compulsive disorder and women should be taken care of more in order to avoid disorders like depression. Midwife clinicians caring for women need to be aware of the impact of these symptoms and attention for mental health in women.
Mitra Barati , Samileh Noor Bakhsh, Azardokht Tabatabee , Farideh Ebrahimi Taj , Mahshid Talebi Taher ,
Volume 8, Issue 2 (Summer 2008)
Abstract
Background & Objective: Respiratory tract infections causes 4.5 million children death in the world annually that occur mostly in developing countries like Iran. Bacterial and viral pathogens are responsible for this event and Adenovirus is one of the major responsible agents. According to multiple survey, incidence of viral pathogens in different world region is different so local survey is needed to describe regional incidence of different viral pathogens. Rapid test for detection of respiratory pathogens help us to select appropriate treatment and avoidence of antibiotic overusage. So abuse the aim of this study was to evaluate incidence and clinical presentation of Adenovirus infection in children in Tehran with rapid test. Methods:This study is a descriptive-cross sectional analysis. All 3 month to 15 year old children with upper respiratory tract infection that come to OPD of Rasol-e-Acram Hospital in one year(1385) are included. Direct smear of patient’s throat was evaluated by rapid chromatography test for adenovirus infection. SPSS software was used to analyse the data. Results: 160 children with upper respiratory tract infection with a mean age of 61.5 months were evaluated. 57.5% were boys and 42.5% were girls. 77.4% had fever, 66% had sore throat, 37.4% had cough, 27% pharyngeal exudate, 16.4% had abdominal pain, 15.7% had vomiting, 13.8% had cervical lymphadenopathy, 10% had diarrhea, 5.7% had petechea in palate and 1.9% had conjectivitis. They admitted 24% in spring, 14.1% in summer, 23.1% in fall and 38.5% in winter. Adenovirus infection was detected in 10(6.3%) cases, 4(40%) boys and 6(60%) girls with mean age of 83.7(SD=58.5). they were detcted 20% in spring, 30% in summer, 30% in fall and 20% in winter. Conclusion: Adenoviruses are responsible in 6.3% of upper respiratory infections in children. They become less prevalent with increasing age. Its prevalence did not obey seasonal pattern. Fever and sore throat are most common clinical signs and cervical lymphadenopathy is more prevalent in adenovirus infection than others.
Ghiti Rahemi , Farideh Mostafazadeh, Mehrnaz Mashofi ,
Volume 8, Issue 2 (Summer 2008)
Abstract
Background & Objective: As cancer of cervix is one of the important facts, for women and probably causes in presence, furthermore early diagnosis and management in primary stages is very effective for prognosis of the disease and survival, the aim of the study was to measure the probable relationship of contraraceptive devices with cervical lesions. Methods: This study was a descriptive analytic study that was done by referring to all pathologic center (6 centers) in Ardabil and reviewing 399 reports of pap smear through sampling method (one of them because of chemotherapy was excluded from the samples) Results: In this study 90 persons 22.5% of pop smear’s study were normal and 309 persons 77.5% were abnormal that include nonspecific cervicitis (298 persons) specific cervicitis (192 persons) and epithelial cell abnormality (105 persons) Regarding the use of contraceptive devices, 15 persons didn't use any device 3.8% And 172 persons 43% were using one of the natural methods or tubal ligation, and 131 persons were using OCP pills 32.9% 63 persons were using IUD 15.8% 18 persons 4.5% were using condom, and also DMPA was not used. Through chi test it was found that there was significant relationship between contraceptive methods and epithelial cell abnormality (p=0.008) and imperavite cervicitis (p=0.001). There was a meaningful relationship. Conclusion: There was a meaningful relationship between using contraceptive methods and nonspecific cervicitis.
Farideh Ebrahimi Taj, Abdolhasan Mohammadi Khangah, Mojdeh Ramezani, Khatereh Anbari,
Volume 9, Issue 3 (autumn 2009)
Abstract
Background and Objective: Intradermal Purified Protein Derivative PPD test is a reliable test assessment of primary mycobacterial infection. In this test the specific antigen is Purified Protein Derivative (PPD). The reaction were assessed by touching, the induration's diameter after 48 &48hours. We compared the induration's size 48 and 72 hour in this study. Methods: At this semi experimental study a 5 unit PPD was administered to 120 healthy medical students. Results: The measurements made at 72 h were significantly (4.22 mm) (p<0.001) higher than those made at 48h (2.79 mm). The reading taken at 72 h were 1.47mm larger than at 48 h recovery. There were significant differences between induration size of 48 and 72h between male and female. Conclusion: This study demonstrates that, in adults, the size of the 5 U Monteux reaction is significantly larger at 72h compared to the reaction at 48h. We suggest to read PPD after 72 hours if the PPD is negative after 48 hours.
Fariba Sadeghi Movahhed , Parviz Molavi , Farid Gossili , Touraj Rahmani , Firouz Amani , Amir Masoud Rostami ,
Volume 12, Issue 1 (spring 2012)
Abstract
Background & Objectives: Insomnia is one of the most common sleep disorders in the world. It causes disruption in daily activities and increases the risk of major depression. Hence, clinically the appropriate and persistent treatment of insomnia is very important. Using of hypnotic drugs such as benzodiazepines is the common treatment for insomnia but they show several side effects and it seems that new medications should be used for treatment of sleep disorders. The aim of this study was comparison between the effects of electromagnetic therapy and conventional drug usage in the treatment of insomnia. Methods: In a blind randomized clinical trial study, 60 people referred to the private office of the psychiatrist and experienced more than 3 months extended primary insomnia were selected. They were diagnosed by DSM-IV criteria and had no other underlying problems. The subjects were divided in two groups: 30 people in each and treated electromagnetically or with Alprazolam for 3 weeks. Before treatment, immediately and one month after treatment, quality of sleep and severity of the insomnia were evaluated by using the standard questionnaires and finally, the results were analyzed statistically. Results : In this study, 60 individuals participated from whom 28 were male (46.7%) and 32 patients were female (53.3%).The mean age was 37.3 years old in a range of 17- 65. The mean point of each questionnaire, before and immediately after treatment significantly didn't show any difference but one month after treatment, there was a significant difference in both groups. Conclusion : To treat insomnia, electromagnetic therapy appears to be used as a replacement for sedative medicines. It also has more stability in comparison with other sedative medicines and no side effects have been reported yet.
Touraj Rahmani , Farid Bahrpeyma, Manoochehr Iranparvar , Mohammad Taghikhani ,
Volume 14, Issue 3 (Autumn 2014)
Abstract
Background & objectives: Type 2 diabetes mellitus results in vascular dysfunction and reduction of nitric oxide (NO) level. In this study the effect of electromagnetic field (EMF) on NO level, an effective factor in increasing blood flow, and on ankle brachial index (ABI) as a n index of lower extremity blood flow in type 2 diabetic patients, have been investigated. Methods: This study was a randomized controlled clinical trial carried out in Imam Khomeini hospital of Ardabil and Mehr physiotherapy center in 2013. Thirty diabetic patients after initial pilot study participated in this experiment based on inclusion and exclusion criteria. Then, they were randomly assigned into two equal groups, electromagnetic therapy and control. The baseline levels of ABI and NO of both groups were measured. Patients in electromagnetic group were exposed to 10 Hz EMF radiation (with intensity of 8 mT) together with scanning lower limbs (three sessions per week, and 40 minutes per session for 8 weeks). The control group did not receive any treatment. After eight weeks, the amount of ABI and NO level were recorded. For statistical analysis paired t-test and independent t-test were used in SPSS 19 software. Results: Statistical analysis showed significant differences between pre (1.009±0.02) and post (1.052±0.02) measurement of ABI of diabetic patient after applying magnetic field ( P = 0.013). However, there was no significant difference between p and after measurement of ABI and NO level in controlgroup and also NO level in magnet groups ( P> 0.05). Difference between pre and post therapy of ABI in electromagnetic group (0.05±0.01) showed significant increase compared with control group (0.004±0.003) ( P = 0.001). Conclusion: Increase in ABI after 8 weeks electromagnetic therapy could be considered as an accretion index in blood flow in lower extremity.
S Farid, H Peeri Dogaheh , M Ghiami Rad ,
Volume 15, Issue 3 (autumn 2015)
Abstract
Background & objectives: Drug resistance is one of the most problems in controlling microbial infections which assumes to be ever-increasing problem all through the world. Production of extended-spectrum &beta-lactamases enzyme (ESBLS) can cause a resistance to antibiotics of gram negative bacteria. The main purpose of this study was to determine antibiotic sensitivity patterns and SHV-1 genes frequency in collected urinary samples from hospitalized patients in Ardebil.
Methods: 400 isolated Enterobacteriaceae from urinary samples were recognized using an ordinary biochemical method. Antibiotic sensitivity test was conducted by Kirby and Bauer. The combined disk method was also utilized as a confirmatory test. The results were compared to clinical and laboratory standards institute (CLSI) standards. Finally, ESBL positive isolates were investigated by PCR method regarding the SHV-1 gene.
Results: From the total of 400 urinary isolates Enterobacteriaseae resistance to Ampicilin, Nalidixicacid, Co-trimoxazole, Cefotaxime, Ceftazidime, Ceftriaxone, Ciprofloxacin Ceftizoxime, Cefixime, Gentamycin, Imipenem were 82.5, 62.3, 67, 36, 49.5, 50.3, 52, 36, 41, 24.8 and 7.7 percents, respectively. 150 isolates (37.5%) were positive ESBL, and among all, 28 isolates (18.7%) contained SHV-1 gene.
Conclusion: According to obtained results from the study, regarding high percentage of resistance to antibiotics and high reduction of ESBLS in bacteria from who suffered from urinary infections, taking some logical steps for prevention seems to be essential.
َarash Mehri Pirayvatlo , Reza Alipanah-Moghadam , Mohammad Mazani, Farideh Manafi, Vadood Malekzadeh, Ali Nemati, Abbas Naghizadeh Baghi ,
Volume 16, Issue 4 (winter 2016)
Abstract
Background & objectives: Iron overload is involved in the pathophysiology of many diseases including diabetes. In fact, the excess iron by creating free radicals makes damage to pancreas and leads to insulin resistance and diabetes. Andrographolide extract has hypoglycemic and antioxidant properties. This study has surveyed the effects of andrographolide on blood glucose and lipid profile in rats with secondary iron overload.
Methods: In this experimental study, 36 male Wistar rats were randomly divided into 6 groups: the healthy control group, secondary iron overload group, secondary iron overload groups treated with a dose of 3.5 and 7 mg/kg of andrographolide extract, and andrographolide groups treated with a dose of 3.5 and 7 mg/kg of extract. Iron and extract were injected for 6 and 12 days, respectively. Blood samples were taken for measurement of blood glucose and lipid profiles. Data were analyzed using ANOVA test.
Results: The pathological results of samples from liver of animals receiving iron showed that the iron was deposited in the liver tissues. Iron injection significantly increased blood glucose levels compared to healthy control group (p<0.05). In the iron overload group, andrographolide extract with a dose of 3.5 mg/kg or 7 mg/kg significantly decreased blood glucose levels (p<0.05). Iron injections did not increase the serum triglyceride and cholesterollevels. Injections of andrographolide extract with a dose of 3.5 mg/kg and 7 mg/kg, significantly decreased the cholesterol levels compared to iron receiving group (p<0.05).
Conclusion: Results of this study showed that the andrographolide with different doses may be effective in the treatment of diabetes by reducing serum glucose and cholesterol levels.
Iraj Faizi, Saeid Smaeilpour, Ali Nemati , Khatere Isazadeh, Farideh Faizi, Vahid Montazeri,
Volume 17, Issue 3 (autumn 2017)
Abstract
Background & objectives: The use of supplements such as L-carnitine, optimum nutritional support and early feeding after surgery in cancer patients can be important in the prevention of cancer complications. The aim of this study was to determine the effects of early L-carnitine-rich feeding on complications of esophageal cancer surgery and duration of hospitalization.
Methods: In a clinical trial, 50 patients with esophageal cancer under surgery in two equal groups were randomly selected. Nutritional information was obtained using food record questionnaire. Basic blood samples and 24-hour urine samples were taken in order to measure the hematological parameters (like blood cell count, hemoglobin, hematocrit and blood urea) and nitrogen balance, respectively from two groups at the beginning and end of the study. Then, the intervention group received 3 g L-carnitine daily in 3 doses on the first day after the complementary operation, with a routine hospital diet at each meal, and the control group received a routine hospital diet for ten days. Data were analyzed using independent t-test, paired t-test and chi-square test.
Results: The results showed that changes in the mean BUN and nitrogen balance were significantly different after intervention between the study groups (p<0.05). Patients with early L-carnitine-rich feeding had less hospitalization time in hospital wards and were discharged earlier (p<0.05).
Conclusion: The results of this study showed that early L-carnitine-rich feeding after surgery has probably a positive effect on the duration of hospital stay in patients with esophageal cancer.
Farid Manafi , Reza Alipanah-Moghadam , Ali Nemati, Vadood Malekzadeh, ,
Volume 17, Issue 4 (winter 2017)
Abstract
Background & objectives: Andrographolide has potent antioxidant properties. There is still not a complete understanding of the antioxidant effects of andrographolide. In this study, the effect of andrographolide on the serum antioxidant activity of superoxide dismutase and catalase was investigated in the rats with secondary iron overload.
Methods: In this experimental study, 32 rats were divided into 4 groups of 8 each. The groups included: 1-Control 2- Receiving iron 3- Receiving iron treated with 7 mg/kg andrographolide 4- Receiving 7 mg/kg andrographolide. The serum activity of superoxide dismutase and catalase and serum level of malondialdehyde (MDA) was measured using colorimetric method. Prussian blue was used to evaluate iron deposition in liver.
Results: The results showed that iron was deposited in the liver. The activity of superoxide dismutase and catalase in the secondary iron receiving group, compared to control group, was significantly increased (p<0.05). The activity of catalase was significantly decreased in the group receiving iron and treated with andrographolide, compared to the control and iron receiving groups (p<0.05). Also, the activity of superoxide dismutase in the group receiving iron and treated with andrographolide decreased significantly compared to the iron receiving group (p<0.05). Serum levels of malondialdehyde in the iron receiving group were higher than the control group (p<0.05). Serum levels of malondialdehyde in the group receiving iron and treated with andrographolide, compared with the iron receiving group, showed a significant decrease (p<0.05).
Conclusion: Andrographolide (7mg/kg) reduced the serum activity of catalase and superoxide dismutase and malondialdehyde serum levels in rats with secondary iron overload.
Iraj Feizi, Somaieh Matin, Hasan Ghobadi, Saeed Hosseininia, Susan Mohammadi Kebar, Farideh Feizi, Hossein Salehzade,
Volume 19, Issue 3 (atumn 2019)
Abstract
Background & objectives: Hydatid cyst is a major hygiene problem in Iran. In 80% of cases, only one organ is involved. However, multiorgan involvement has also been rarely reported. But it seems, the prevalence of hydatid cyst with the involvement of more than one organ in Iran is more than other world. The aim of this study was to evaluate the patients with hydatid cyst multi organ involvement in Ardabil province in northwest of Iran.
Methods: In this retrospective study, 34 patients with hydatid cyst with involvement in more than one organ were included. For each patient, a pre-designed questionnaire including name, age, education level, occupation, place of residence, cyst location, clinical manifestations and serologic test results were completed. Patients, who had previously a history of treatment due to hydatid cyst, were excluded from the study.
Results: The mean age of patients was 36.41 years. 61.8% of the patients were housewives and 64% were rural residents. The most commonly involved organs was liver and simultaneous involvement of liver and lung was observed in 38.2% of patients and was more in women. The association of the right lung cyst with the liver cysts was greater than that of the left lung. Only in 43% of the patients, the serologic test was positive for hydatid cyst, and the relationship between serologic test and type of involvement was not significant.
Conclusion: Regarding the high incidence of hydatid cyst involvement in more than one location in our region, in all patients, especially women with liver hydatid cyst, other organs, especially the lungs, should be investigated
Faride Bastani, Fateme Farajtabar,
Volume 20, Issue 1 (spring 2020)
Abstract
Background & objectives: Chronic obstructive pulmonary disease (COPD) is one of the most common diseases in the elderly. Elderly people with this disease have many problems, as sleep disorders, that can cause many complications such as falls, depression, memory disorders, irritability, fatigue, difficulty concentrating and dementia. The aim of this study was to determine the severity of insomnia in elderly patients with chronic obstructive pulmonary disease.
Methods: This is a cross-sectional, descriptive study that was performed on 170 elderly people with COPD referred to Hazrat Rasoul Akram Hospital in Tehran. The research instruments were short form of cognitive test and demographic characteristics, insomnia severity questionnaire. Data analysis was performed in SPSS software (V.16), using Pearson and Spearman correlation test, one-way ANOVA, independent t-test, logistic regression analysis and Tukey post hoc analysis.
Results: The mean and standard deviation of insomnia in the elderly were found to be 14.4±5.6 which indicated moderate insomnia. Factors such as gender, marital status, patient's occupation, history of sleep disorders, and history of hypnotic drugs use and duration of COPD were the variables that were significantly associated with patients' insomnia. (p<0.001)
Conclusion: Insomnia disorder in the elderly will have adverse consequences. Hence the control of effective factors in these patients can improve their health and quality of life.
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