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Showing 4 results for Bayrami
Roghaiyeh Bayrami , Niloofar Sattarzade, Fatemeh Ranjbar Koocheksarai , Mohammad Zakariya Pezeshki ,
Volume 8, Issue 4 (Winter 2008)
Abstract
Background & Objectives: Pregnancy is one of the most sensitive periods of lifetime and married life and sexuality may bring about numerous physical and psychological changes. Lack of attention to sexual matters during pregnancy may cause sexual dysfunction in each of couples. The aim of this study was identifying male sexual behavior and its relevant factors during the partner’s pregnancy. Methods: This was a descriptive-analytical study in which 350 men, whose wives were pregnant, were selected in two stratified stages. The instrument for data collection was Arizona Sexual Experiences Scale- male questionnaire. All data were analyzed by SPSS11.5. Descriptive information was used for describing the frequencies and also the x2 test was used for determining relation ship among variables. Results: The findings revealed that 21.3% of men in the first trimester, 19.3 in the second and 28.3 in the third trimester had sexual dysfunction. In each trimester, inability to reach orgasm was the most common sexual dysfunction in men. Frequency of vaginal coitus decreased in 64.9% of men and in 46.6 % of them fear from risk for fetus health during vaginal coitus was the essential reason for this reduction. There were significant differences between sexual dysfunction and fear from risk for fetus health and guilt feeling of sexual activity. Therefore decreased vaginal coitus caused sexual dysfunction. Conclusion: As men’s knowledge and attitudes about sexuality affect their sexual behavior during pregnancy it is crucial to provide proper consultation regarding sexual relations in prenatal care services.
Maryam Salem , Tooba Mirzapour, Aboulfazl Bayrami, Mohsen Sagha, Asadollah Asadi,
Volume 17, Issue 1 (spring 2017)
Abstract
Background & objectives: According to importance of bone marrow mesenchymal stem cells in production of different cell lines, transplantation of these cells are used for treatment of many different diseases during cell therapy. Viability and proliferation of these cells after transplantation are very important. Since infertility is as public health problem in men and women, the scientists attempt to produce germ cells from differentiation of stem cells. It is supposed to use these cells for treatment of different illnesses especially for men with lack of germ cells in testes in future. However, in using stem cells for cell therapy the culture medium should be designed to increase the number of cells and efficiency of transplantation and to guarantee the health of the cells in terms of DNA damage. This study designed a suitable culture medium in order to increase the number of colonies and decrease the cell injuries.
Methods: In this study mesenchymal stem cells isolated from bone marrow of mice and exposed to retinoic acid (RA) with concentration of 10-6 M and Sertoli cells condition medium. Since mesenchymal stem cells (MSCs) produce fibroblastic colonies so the number of colonies was counted every 3 days after culture (days of 2, 5, 8, 11, and 15) under inverted microscope. The staining of ethidium bromide-acridine orange was also done for determination of apoptotic nucleus in days of 10 and 15 after culture.
Results: The results showed that the effects of retinoic acid on grow and viability of MSCs is related to the time. It seems that RA increased the proliferation of the cells and the number of colonies increased in low time but the apoptotic cells elevated with increasing the time of culture. Condition medium of Sertoli cells also increased the proliferation of bone marrow stem cells.
Conclusion: According to proliferative properties of condition medium, it seems that using condition medium together with RA is better than RA alone for differentiation of MSCs to germ cells.
Ahmad Salimi, Zhaleh Jamali, Mohammad Shabani, Deniz Bayrami, Amin Ashena Moghadam,
Volume 24, Issue 3 (Autumn 2024)
Abstract
Background: Ifosfamide-induced kidney damage is an important toxicity in children and adults undergoing chemotherapy. Studies have previously demonstrated that toxic metabolites of ifosfamide, such as acrolein, are associated with depletion of antioxidants, oxidative stress, and mitochondrial impairment, which may predispose the kidney to ifosfamide toxicity. Plant-derived active compounds, such as chrysin, found in fruits and vegetables, are renowned for their antioxidant and mitochondrial protective effects against toxicity-related mitochondrial damage and oxidative stress.
Methods: In this work, the protective effects of chrysin on ifosfamide-induced nephrotoxicity in male Wistar rats were investigated using biochemical, histopathological, and mitochondrial approaches. The animals were randomly divided into four groups: control, ifosfamide, ifosfamide + chrysin, and chrysin groups. Chrysin (25 mg/kg, i.p. daily) was administered to rats for 2 consecutive days, and ifosfamide (500 mg/kg, i.p.) was administered on the third day.
Results: The data demonstrated that pretreatment with chrysin significantly increased mitochondrial succinate dehydrogenase activity and protected against mitochondrial swelling, mitochondrial membrane potential loss, reactive oxygen species formation, lipid peroxidation, and glutathione depletion (p<0.001). Histopathological results showed that chrysin had protective effects and reduced histopathological abnormalities caused by ifosfamide.
Conclusion: These observations confirmed that chrysin pretreatment protects the kidneys against mitochondrial dysfunction, oxidative stress, and histopathological abnormalities induced by ifosfamide.
Soheila Derisavy Jorfian, Ghadir Pourbayramian, Erfan Belalzadeh,
Volume 25, Issue 1 (Spring 2025)
Abstract
Background: Clinical education, as a cornerstone of dental training, plays a pivotal role in cultivating professional dentists and preparing them for therapeutic challenges. Given that the quality of clinical education directly influences students' professional competencies and subsequently the quality of healthcare services, identifying the factors affecting its quality is of paramount importance. Considering the key role of dental students as primary stakeholders in clinical education and the significance of their perspectives for program reforms, and noting the absence of a comprehensive study in this regard at Ardabil University of Medical Sciences, the present study was conducted to identify factors affecting the quality of clinical education and to propose improvement strategies based on students' viewpoints.
Methods: This descriptive-cross-sectional study was conducted in the second semester of the 2024 academic year among dental students at Ardabil University of Medical Sciences who had completed at least two semesters in clinical education settings and was willing to participate. Using Morgan's table, a sample size of 177 students was estimated. Participants were selected randomly from available students in various departments of the dentistry faculty. The data collection instrument was a questionnaire comprising 26 items across 5 main domains of clinical education quality, rated on a five-point Likert scale. A significance level of 0.05 was considered.
Results: The findings indicated that educational objectives and programs (β=0.328) and instructor’s performance (β=0.303) had the most significant impact on the quality of clinical education. Subsequently, the educational environment (β=0.218) and interaction with students (β=0.188) were of lesser importance, respectively. Evaluation (β=0.136) had the least impact on the quality of clinical education. Furthermore, older students and those in higher academic semesters evaluated the quality of clinical education more positively. No significant differences were observed in the evaluation of clinical education quality based on gender or clinical education groups.
Conclusion: From the perspective of dental students at Ardabil University of Medical Sciences, educational objectives and programs, along with instructors, are the most decisive factors in the quality of clinical education. Enhancing these two components, in addition to improving the educational environment and student interaction, is essential for increasing the quality of clinical education. It is recommended that educational policymakers focus on strengthening these areas.
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