---

 
Background & objectives: Minimizing muscle damage and inflammation can boost the immune system and improve sport performance. The aim of this study was to investigate the effect of 8 weeks of resistance training-cold water immersion and curcumin supplementation on muscle injury and inflammation following a session of acute strength activity in futsal players men.
Methods: twenty futsalist volunteered to participate in the study and were randomly assigned to experimental and control groups. Blood sampling was performed after 12 hours of night fasting during four stages. After the first phase of blood sampling, both groups were performed one session of acute circular strength training, then, the second phase blood sampling was performed. 48 hours later, the experimental group performed 8 weeks of circular resistance training, three sessions per week as in the acute strength training and were immersed immediately after exercise, 20minutes at 5-10°C in cold water and used 150mg curcumin supplementation. forty eight hours after the last training session and last using curcumin, blood sampling was performed in both groups. Then, both experimental and control groups performed the second acute circular strength training and the fourth stage blood sampling was performed. The differences of variables at different time intervals were compared with 2×4 two-way ANOVA and differences between the two groups were investigated  with Independent-Samples T-Test at significance level of p<0.05.
Results: Creatine kinase and white blood cells significantly increased in both groups after the first acute strength activity (p=0.049). Performing 8 weeks of resistance training-cold water immersion and curcumin supplementation, significantly decreased creatine kinase and white blood cell counts (p=0.024). Also, 8 weeks of resistance training-cold water immersion and curcumin supplementation, significantly reduced creatine kinase and white blood cells following acute second strength activity (p=0.021).
Conclusion: Appears to, 8-week resistance training-cold water immersion and curcumin supplementation following a session of acute strength training reduce muscle injury and inflammation in futsal players  men.