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Comparison of the Prevalence of Thrombocytopenia in Deceased and Recovered COVID-19 Patients Admitted to the ICU of Imam Khomeini Hospital, Ardabil
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Maryam Ekran    , Atabak Sedigh-Namin , Effat Iranijam , Shafagh Aliasgarzadeh * , Nazli Javaheri , Afshan Sharghi |
| Department of Internal Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran , Sh.aliasgarzadeh@arums.ac.ir |
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Abstract: (267 Views) |
Background: Thrombocytopenia is a clinical manifestation of coronavirus disease 2019 (COVID-19), potentially leading to bleeding and affecting disease prognosis. This study aimed to compare the prevalence of thrombocytopenia in deceased and recovered COVID-19 patients admitted to the Intensive Care Unit (ICU) of Imam Khomeini Hospital, Ardabil.
Methods: This cross-sectional study was conducted on 458 patients with confirmed COVID-19 admitted to the ICU of Imam Khomeini Hospital from April to September 2021. After applying exclusion criteria, 403 patients (136 recovered and 267 deceased) were analyzed. Demographic, clinical, and laboratory data, including thrombocytopenia severity, were extracted from medical records and analyzed using statistical tests (e.g., Chi-square and logistic regression).
Results: Thrombocytopenia was observed in 18.4% (25 of 136 patients) of recovered patients and 76% (203 of 267 patients) of deceased patients. The mean age of patients with thrombocytopenia was significantly higher in the deceased group (70.27±13.62 years) compared to the recovered group (61.20±15 years) (p=0.001). Heart failure was significantly associated with thrombocytopenia (p=0.038). Patients treated with remdesivir showed higher thrombocytopenia prevalence in the recovered (84%) and deceased (65.2%) groups, but this was not statistically significant.
Conclusion: Older age and heart failure were associated with increased thrombocytopenia in deceased COVID-19 patients. Severe thrombocytopenia was linked to a higher mortality risk. |
Article number: 8 |
| Keywords: Thrombocytopenia, COVID-19, Intensive Care Unit, Prognosis, Heart Failure |
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Full-Text [PDF 323 kb]
(99 Downloads)
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Type of Study: article |
Subject:
Hematology and oncology
Received: 2025/04/1 | Accepted: 2025/07/30 | Published: 2025/07/28
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| References |
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Ethics code: IR.ARUMS.MEDICINE.REC.1402.078
Ekran M, Sedigh-Namin A, Iranijam E, Aliasgarzadeh S, Javaheri N, Sharghi A. Comparison of the Prevalence of Thrombocytopenia in Deceased and Recovered COVID-19 Patients Admitted to the ICU of Imam Khomeini Hospital, Ardabil. J Ardabil Univ Med Sci 2025; 25 (2) : 8 URL: http://jarums.arums.ac.ir/article-1-2487-en.html
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