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Showing 2 results for Swimming Training

Hamidreza Abri, Minoo Mahmoodi , Siamsk Shahidi ,
Volume 18, Issue 3 (10-2018)

Background & objectives: The aim of the present study was to investigate the effects of   oral creatine supplementation on biochemical markers of liver, kidney and testis in the male rats under swimming training plan.
Methods: In this study, male Wistar rats, weighing 245±5gr, were divided into five groups (n=8): control, exercise plus zero dose, exercise plus low-dose, exercise plus moderate dose and exercise plus high dose of creatine (200,300 and 600 mg/kg/d respectively). Biochemical studies of blood serum were performed ten days after creatine supplementation and swimming exercises. Following serum collection, the alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN), creatinine and testosterone levels were measured using spectrophotometry method. Statistical analysis was performed by SPSS software using mixed model ANOVA.
Results: serum levels of ALP showed statistically significant differences between groups receiving low and moderate doses of creatine compared to both control and exercise with zero dose  (p<0.05). Also, the results of serum levels of BUN, ALT and AST showed there was no significant difference between the exercise plus zero dose of creatine, exercise plus low-doses of creatine group, exercise plus moderate dose of creatine, exercise plus high dose of creatine groups and control group. The exercise group with high doses of creatine significantly showed a higher serum creatinine level than control group (p<0.05).The serum testosterone level was significantly higher in the exercise with moderate doses of creatine group than in the control group and exercise plus zerecaratin dose (p<0.05).
Conclusion: The results suggested that short-term creatine supplementation (up to 10 days) might adversely affect some biochemical markers of liver, kidney and testis. However, further studies are necessarily needed to clarify the consumption of short-term creatine supplementation.
Sepideh Ghasemian , Parvin Farzanegi, Lida Moradi,
Volume 19, Issue 3 (10-2019)

Background & objectives: In the pathogenesis of endometriosis, a variety of genes are involved. The aim of this study was to investigate the GATA2 gene expression changes in endometriosis rat model following a period of aerobic exercise and vitamin B6 intake.
Methods: For this purpose, 25 adult Wistar rats were randomly divided into 5 groups, including: healthy control, patient control, patient+training, patient+vitamin, patient+vitamin+ training. In order to create an endometriosis model, rats were first anesthetized and after opening abdominal muscle, ovarian tissue and part of uterine tissue were removed and were inserted into a sterile container with one cc of PBS and sliced. Tissue fragments were transplanted into the abdominal and ovarian areas. The amount of vitamin intake was 60mg/kg and swimming program lasted 8 weeks, 30 minutes a day, five days a week. One-way ANOVA test and Tukey post hoc test were used for data analysis.
Result: The results showed that a period of swimming exercise program in the patient + training group significantly increased the GATA2 level compared to the patient control group (p≤0.001). Also, the GATA2 gene expression level was significantly increased in the patient + training + vitamin group compared to the patient control group (p=0.002). However, its level in the patient group was significantly lower than that of the healthy control group (p≤0.001).
Conclusion: Regular aerobic exercise combined with intake of vitamin B6 may decrease GATA2 gene expression level in endometrial rat model.

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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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