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Showing 45 results for Stress

Mohammadali Mohammadi , Hosein Doostkami , Behrooz Dadkhah , Seyedhashem Sezavar ,
Volume 2, Issue 2 (6-2002)
Abstract

  Background & Objectives : Coronary artery disease is one of the most important mortality causes in developed and developing countries. Many risk factors can influence coronary artery disease some of which can be controlled and prevented. Information should be given to people for controlling these factors and prior to this information – giving, the primary awareness of them about risk factors needs to be ascertained. This research is a study of the knowledge, attitude and practice of Ardabil people about CAD risk factors.

  Methods : This descriptive analytic study was done on 384 individuals (female and male) over 20 years old. These subjects were selected from five clusters. Synthetic questionnaire was used for data collection through direct interview at home. The collected data was then analyzed by SPSS software.

  Results : 50.5% of samples were females. 27.3 % of the subjects were high-school graduates. Most of them (70%) were aware of stress and lesion as risk factors. 66.9% of them were aware only of the effect of immobility on coronary artery disease but 13% of them had regular physical activity. 52.1% of them were aware of the harmful effect of salt on CAD, but 15% of them had low salt intake. 48.2% of people were aware of benefit of liquid oil on health, but only 25% of them consumed it. Results showed that, 48.2%, 51.3% and 40.9% of individual had moderate knowledge, positive attitude, and weak practice, respectively. The relationship among variables was significant (P<0.0001), and practice of people has been increased with increasing of knowledge and attitude.

  Conclusion : Regarding these results, regular programs are necessary for increasing awareness and practice of people as primary preventive steps for controlling CAD.


Mohammadhosein Dehghan , Bahareh Rajaee Far , Farnaz Ehdaivand , Firooz Amani ,
Volume 4, Issue 3 (9-2004)
Abstract

  Background & Objectives: Preeclampsia is still one of the leading causes of maternal and fetal morbidity and mortality. Despite active researches over the past many years, the etiology of this disorder in human pregnancy is an enigma. Oxidative stress has been implicated in the pathophysiology of preeclampsia. Essential nutrients such as vitamin C can scavenge free radicals inducing cellular damage. The present study was designed to investigate the plasma levels of vitamin C in patients with preeclampsia (case) and normotensive pregnant women (control).

  Methods: In this case-control study vitamin C as an antioxidant was estimated and compared spectrophotometrically in 40 preeclamptic and 80 normotensive pregnant women referring to Alavi Hospital of Ardabil province, Iran. The collected data were analyzed using descriptive and inferential statistics.

  Results: The plasma levels of vitamin C were significantly lower in patients with preeclampsia (0.147 ± 0.030 mg/dl) compared to controls who were normotensive pregnants (0.347 ± 0.119 mg/dl).

  Conclusion: Attempts at prevent preeclamsia are justified but since no reliable screening test has been offered as yet for women at risk, assessment of plasma level of vitamin C in patients prone to preeclampsia is strongly suggested.


Kaviean Ghandhary, Mohammad Afshar ,
Volume 5, Issue 1 (4-2005)
Abstract

 Background & Objectives: Demographic and environmental factors are effective in the pathogenesis and prevention of Parkinson Disease (PD). Sex, family history of PD, farming, literacy, history of head trauma, smoking, well water consumption, overusing oil seeds and contact with herbicides and pesticides are apparently effective in this regard. This study set out to investigate the risk factors of PD.

 Methods: 100 patients with PD and 200 age matched controls refering to Neurology clinic of Birjand UMS were investigated in this case-control study during 2002-2003. PD was diagnosed by a neurologist and the demographic and environmental factors were recorded in a questionnaire. Student T and Chi-Squire tests were used for statistical analysis.

 Results: 68% of the cases and 53% of the controls were male. Family history of PD, farming, literacy, stress and well-water consumption were significantly more frequent in PD group(p<0.05). Smoking and overusing oil seeds were more frequent in control group (p=0.007, p=0.001 respectively). Frequency rate of contact with herbicides, pesticides and history of head trauma were not significantly different in case and control groups. Conclusion: Family history of PD, farming, literacy, stress and well-water consumption are risk factors of PD, while smoking and using oil seeds could be protective factors against PD.


Ahmad Hashemzadeh, Farhad Heidarian,
Volume 5, Issue 2 (6-2005)
Abstract

  Background & Objectives: Respiratory distress is one of the most important causes of children admission in hospitals. In most cases, it is due to pneumonia, asthma or acute bronchiolitis. Since theses diseases have a lot of symptoms in common, we decided to study these disorders in more details to facilitate the appropriate diagnosis and treatment based on clinical, laboratory and radiologic findings.

  Methods: 238 children who suffered from respiratory distress and were admitted to pediatric ward in Ghaem hospital were studied. This descriptive study was performed during 3 years including 2 retrospective and one prospective year. The relationship between variables was analyzed using chi-square test.

  Results: The patients were six months to five years old. Pneumonia (40.3%) asthma (30.3%) and bronchiolotis (16.8%) were the most common causes of respiratory distress. Totally, 61.1% of the patients were male. The mean age of the patients was 10.3 months in bronchiolitis and 36.6 months for asthma. The most common symptom among these three diseases was tachypnea. Most of the patients were admitted in winter and fall respectively. The main radiologic pattern in pneumonia was pulmonary infiltration and for asthma and acute bronchiolitis it was pulmonary hyperinflation.

  Conclusion: Proper attention to signs and symptoms as well as laboratory and radiologic fndings is necessary for accurate diagnosis. In this study the most common cause of respiratory distress in children under 5 was found to be pneumonia, asthma and bronchiolitis respectively.


Fariba Kahnamouei Aghdam , Farnaz Ehdayivand, Faride Mostafazadeh, Godrat Akhavan Akbary , Mohammad Sadeghi,
Volume 5, Issue 3 (9-2005)
Abstract

  Background & Objectives: Respiatory Distress Synderome (RDS) is one of the major risks of elective cesarian section whose negative health and econemical outcomes are obvious. Maternal prophylactic injection of corticosteroid drugs can reduce RDS of neonate to some extent. On the other hand corticosteroid drugs have some side effects such as delay in the healing of the incision. This study considered the effect of betamethasone on surgical incision.

  Methods: This study was conducted on 60 primipara women divied into two equal groups that were candidate for elective cesarean. We injected betamethasone (IM) to trial group twice 48 hours poior to operation, (every 24 hours) and complication of surgical incision was clinically evaluated within 7 days after operation in both groups. The data were collected and analyzed by SPSS software chi-square and Fisher tests.

  Results: Most patients (60%) were 20-30 years old and the average age in both groups was 21. The relative frequency of patients with complication of surgical incision in trial group (betamethasone recipients) was 30% and in control group was 23.33% (the difference between them was not statistically significant). The most common complications were erythema and hyperemia. Other complications observed in 15% of the patients included serousal discharge, local warmness and enduration. Rgarding these complications also there wasn’t a statistically significant difference between two groups.

  Conclusion: Betamethasone does not increase early onest complications of surgical incision and we can safely use betamethasone prophylactically for fetal maturion in elective cesareans.


Mohammad Narimani , Yoosof Khonya , Abbas Abolghasemi , Masoud Ganji , Gafar Majidi ,
Volume 6, Issue 2 (6-2006)
Abstract

 Background & Objectives: Clinical findings show that stress can gradually affect the activity of various systems of the body such as immune system and impair them. Different variables potentiate and modify this effect. This research aimed at studying the relationship of personality traits (self-respect, tenacity, type A personality), stress, and stress coping skills with immune system status in nurses.

 Methods: In this descriptive-analytical study, 246 individuals were selected by simple random sampling method. At the first stage, the subjects on the job completed the questionnaires of self-respect, tenacity, type A personality, stress, and stress coping skills. At the second stage to determine the amount of antibodies, 2-cc blood of the subjects was assessed. The data were analyzed using correlational methods.

  Results: The findings indicated a significant, positive and meaningful relationship of immunoglobulin antibody with “self-respect”, and IgM antibody with “type A personality” in male nurses (p<0.05). But there was no significant relationship between the immune system variables and tenacity, stress, and stress coping skills. From among the predictive variables (self-respect, tenacity, type A personality, stress, and stress coping skills) only the stress variable had significant relationship with the criterion variable (IgA antibody)(p=0.05).

 Conclusion: Regarding the results it can be said that self-respect may adjust IgG variable in stress positions (especially in chronic stress). So in hard jobs such as nursing, psychological characteristics should be considered as an important job factor along with physical capabilities.


Akram Kooskki, Mahdi Golafrooz Shahr ,
Volume 6, Issue 3 (9-2006)
Abstract

 Background and Objectives: Oxidative stress has a role in the pathogenesis of type II diabetes due to increase in insulin resistance or disorder in insulin secretion and atherosclerosis. Food antioxadants including carotenoids protect against diabetes by preventing oxidation reactions. Therefore, this study was conducted in Sabzevar to study the relationship between carotenoids and blood sugar and lipids in type II diabetic patients.

 Methods: This cross-sectional analytical study was conducted on type II diabetic patients who were randomly sampled. Their height and weight were measured and relevant data on nutritional intake and frequency in 3 successive days were collected through 24-hour recall. Measures were domesticated and converted to grams. Carotenoids of the intakes were calculated. Blood sugar, triglycerides and serum cholesterol after 12 hours fasting were measured through enzymatic procedures. Data analysis was carried out by descriptive statistics and partial correlation.

 Results: 75 type II diabetic patients with mean age of 54.05±14.2 years, mean BMI of 27.02±5.03 Kg/m2 participated in the study. Their mean blood sugar, triglyceride and cholesterol were 196.36±87.82, 262.84±147.89 and 243.98±60.76 mg/dl respectively. Mean daily intake of beta carotene was 1236.56±810.21 mcg, alpha carotene 878.170±149.04 mcg, lutein 1163.40±819.77 mcg, zeaxanthin and lycopen were 2195.77 ±988.70 mcg.

 Conclusion: Our results showed that most carotenoids negatively correlated though not significantly with their blood sugar and lipids.


Mohammad Mazani , Hasan Argani , Nadereh Rashtchizadeh , Mohammad Rohbaninoubar , Amir Ghorbanihagjo , Reza Mahdavi , Reza Razzaghi , Babak Rahimi Ardabily , Seyedjamal Ghaemmaghami ,
Volume 6, Issue 3 (9-2006)
Abstract

  Background and Objectives: A great amount of evidence shows that Oxidative stress is high among hemodialysis patients. The purpose of present investigation is examination of the effect of zinc supplementation on improvement of oxidative stress in chronic hemodialysis patients.

  Methods: In this double blind clinical trial 65 chronic hemodialysis patients were studied in two groups Group one (35 patients) received placebo and group two (30 patients) received 100 mg elemental zinc (as zinc sulfate) daily for 2 months. The placebo and supplement discontinued in next 2 months. Then, the study continued for two other months in the cross-over from. The levels of serum zinc, total glutathione, malondialdehyde (MDA), total serum antioxidant capacity and the activity of whole blood superoxide dismutase (SOD) were determined on 0th, 60th,120th,180th days, in fasting, predialysis samples. Food record was recorded for one day prior to dialysis in above-mentioned days and their dietary zinc was assessed.

  Results: Basal serum zinc levels in both groups were below 80 μ g/dl. The zinc upplementation led to significant increase in the levels of serum zinc in both groups .The levels of serum total antioxidant capacity, total glutathione and activity of whole blood SOD increased significantly during zinc supplementation period. The concentrations of serum MDA decreased significantly in zinc supplementation period in both groups. During the placebo period the levels of MDA in first group increased significantly, whereas the concentration of glutathione in second group decreased significantly. The body mass index (BMI) values did not change significantly during the study.

  Conclusion: It can be concluded that in patients undergoing hemodialysis the oxidative stress enhanced during nonsupplementation period (zinc sulfate). Low serum zinc levels are improved by zinc administration and zinc supplementation improves oxidative stress.


Parviz Molavi, Hosein Mohammadnia, Roohollah Arab , Akbar Atadokht ,
Volume 7, Issue 1 (4-2007)
Abstract

  Background & Objectives: Tension headache is one of the most common types of headaches that millions of people suffer from it. So far different treatments have been used to confront with tension headaches. According to the studies, tension headaches usually respond well to nonpharamacological treatment. The objective of this survey is the comparison between efficacy and effectiveness rate of SIT and medical treatment for tension headache treatment.

  Methods: In this study, 30 patients who had referred to neurology clinic of Alavi Hospital and private clinics, during the months of June and July in 2003, with chronic tension headache complaint, were selected randomly. These 30 patients were entered to two study groups and the third control groups. The patients in the first and second group received SIT and medical treatment respectively. The third group was considered as the control group and received no intervention. Indices of headache (frequency, severity and duration) were evaluated in 3 stages (Before treatment, after treatment and within one-month follow up period) by using a headache record device for all of patients. The collected data were analyzed by inferential statistical SIT methods, variance analysis and LSD pair comparison.

  Results: The data found from ANOVA methods (Analysis of variance) showed that both methods (Stress inoculation training and medical treatment) are effective in the treatment of chronic tension headache, but comparison between two groups showed that the group who received SIT had a significant difference compared to the group who received medical treatment in terms of efficacy rate on duration and consistency of headache symptom (p<0.05). In other indices of headache (freauency and severity), there was no significant difference between these two groups.

  Conclusion: This study showed that effiectiveness rate of stress inoculation training is more effective than medical treatment of tension headache (in terms of headache symptoms duration and consistency).


Fahimeh Sehhatie Shafaei , Fatemeh Ranjbar Koochaksariie, Morteza Ghojazadeh, Zhila Mohamadrezaei,
Volume 8, Issue 1 (4-2008)
Abstract

Background & Objective: Depression is a debilitating disorder with high prevalence especially in child-bearing women. This study was done to determine relationship between postpartum depression and its various risk factors.
Methods: This was a descriptive-analytic study on 600 women referring to health centers in Tabriz. Data were gathered using a questionnaire including 5 parts: demographic characteristics, mother-newborn characteristics, Rosenberg self-esteem scale, Holms stress scale, Edinburgh Postnatal Depression Scale. These data were analyzed by descriptive and inferential statistical methods in SPSS 14/win software.
Results: In this study 34.7% of mothers were depressed (scores>12). Significant risk factors for postpartum depression were: Marital dissatisfaction, relationship with mother, mother-in law and husband's family, job dissatisfaction, house condition, having an unpleasant
pregnancy experience, unplanned pregnancy, baby care stressors, infant feeding method, nursing problems, mother's self-esteem and stress level.
Conclusion: Concerning high prevalence of postpartum depression in this study and other similar studies and effects of some factors in this disorder, it seems to be necessary to improve the knowledge of mothers and health care staff about this risk factors for reducing effects of this disorder on physical and psychological health of newborns, mothers and
community.
Maryam Saghiri, Niloofar Sattarzadeh, Nosrat Tabrizi, Zakariya Pezeshki,
Volume 8, Issue 1 (4-2008)
Abstract

Background & Objective: Labor pain is one of the most severe pains that mothers experience. Intense pain leads to stress and has unfavorable effects on the mother and fetus. This research was done to determine the effect of using Entonox (N2O) self administration on reducing labor pain in the active phase of labor& delivery, Mode of delivery, and newborn's Apgar score.
Methods: One hundred and twenty primiparous women in 29 Bahman Hospital in Tabriz were included it this randomly single-blind research. In the active phase of delivery, Entonox and Oxygen gases were used. The severity of the mother's pain was asked and was scored according to analogue criterion.
Results: There was a significant difference in frequency of pain intensity in two groups of Entonox and Oxygen. The Mean score of pain intensity in Entonex user, in the first & second stage of labor was 5.93% and 5.82% respectively, while for the oxygen users it was 6.99% and 6.74% which was significant. 41.7% of the mothers in the Entonox group had a severe pain and 11.7% had a very severe pain, whereas in the Oxygen group 58.3% of the mothers had a severe pain and 25% of them had very severe pain (p< 0.001). Meanwhile we found no significant difference between modes of delivery progress of labor and newborn's Apgar
score.
Conclusion: According to research results, Entonox reduces the intensity of labor pain more than oxygen and is effective during the first and second phase of delivery.
Mohammad Aghaeishahsavari , Masoud Noroozianavval, Peghah Veisi , Hasan Argani , Nadereh Rashtchizadeh , Amir Ghorbanihaghjo, Sima Abedi-Azar, Amirmansoor Vatankah,
Volume 8, Issue 2 (6-2008)
Abstract

 Background & Objective: As renin-angiotensin system (RAS) activity could affect the severity of oxidative stress and inflammatory markers the effect of enalapril and losartan on these markers in renal transplant recipients (RTRs) with RAS polymorphisms was assessed.

 Methods: After determination of RAS genotypes including angiotensin converting enzyme (ACE I/D), Angiotensinogen (AGT M235T) and angiotensin II type 1 receptor (ATR1 A1166C) by PCR, seventy-six RTRs recruited to four groups randomly: first group (17 patients) and second group (24 patients) were treated with E (E+: 10mg/daily) and L (L+: 50 mg/daily) alone, respectively. The third group (17 patients as positive control) received E+L (E+L+: 10mg/daily + 50 mg/daily) and the 4th group (18 patients as negative control) received no medication (E-L-). Hs-CRP and total anti-oxidant (TA) as inflammatory and anti-oxidative markers were measured after 2 months. After 2 weeks as washout period, E group changed to L and vice versa as a cross-over design. They were followed for another 8 weeks and hs-CRP and TA were retested.

 Results: Following up the patients (after 2, 4 months of treatment) in treated groups revealed that hs-CRP and TA levels were significantly decreased and increased (consequently) in E+L+, L+, E+ groups (P<0.05). On analyzing the relationship between RAS polymorphisms with baseline hs-CRP and TA levels, CC genotype of ATR1 had lower hs-CRP levels (P=0.04). But none of the RAS polymorphisms could predict the anti-oxidative and anti-inflammatory response rate to the drugs (P>0.05).

 Conclusion: E and/or L reduce hs-CRP and increase TA regardless of the RAS genotypes.


Ferdos Ghomashchi,
Volume 8, Issue 3 (9-2008)
Abstract

 

Background & Objectives: Serious reactions which normally is delayed and occur against serious stressor factors like natural disasters (for example: earth quake, flood and etc) and human made disasters (for example war, murder and etc) calls post traumatic stress disorder (PTSD). The aim of this study was Assessing the effectiveness of teaching problem solving skills in decreasing the symptoms of PTSD.

Methods:The type of this research is experimental. After clinical assessment and selecting with clinical assessment these individuals showed PTSD symptoms through the results of both Mississippi scale and clinical appointment, in which there were 160 cases. The cases were separated to two groups of experimental and control. Through an experimental method, we studied and measured changes of their status before and after examination and only case group had been chosen for problem solving skills teaching. In order to analyze the results of the study, a T test and Variance analysis (ANOVA) were used.

Results: The results showed that 61.6 percent of population showed PTSD symptoms and there was no significant difference between male and female in level of PTSD symptoms. There was a  significant difference between, means level of PTSD in pre-test and post-test conditions, in addition there was no significant difference between levels of PTSD symptoms-decreasing, in female group after intervention, and male group. By comparing mean numbers of samples, in pre-test and post-test results of control and experiment groups in using problem-focused coping skills and decreasing emotion-focused coping skills, there was a significant differences. Also there was not any difference in using levels of coping methods, but indeed in amount of using emotion-focused coping method there was significant difference between male and female.

Conclusion: Presence of significant differences between pre-test and post-test results showed that training problem-solving-skills in decreasing PTSD symptoms is effective.
Saeid Nafisi , Seyed Shamsaddin Athari , Reza Kazemi , Ehsan Hosseini ,
Volume 9, Issue 4 (12-2009)
Abstract

 Background and objectives: During the last years the effects of pulsative electromagnetic fields have been studied in the human and animals nervous system. The using of these fields in today living has caused worriment in safety of human. Stress causes very problems in behavior and function of biological systems. In this survey the effects of electromagnetic fields on stress behaviors of rats have been studied.

 Methods: In this study we aimed to investigate the effects of electromagnetic fields with 700 milli Gauss currency produced by triangle electrical currents with low (10 Hz) and high (110 kHz) frequencies on stress behaviors in 60 adult, male Wistar rats. The rats were divided to two groups of control and test. The animals were exposed to the field for 80 minutes and in order to evaluate the possible effect of electromagnetic fields the Tail pinch (T.P.) test was conducted. The results were analyzed using statistical tests.

  Results: Analyzing of the results of response time and stress behavior by T-test. In the group exposed electromagnetic fields of triangular low waves (10 Hz) for 80 min the results were meaningful (p < 0.05). The response and stressed behavior with this field is decreased very much. The results of two groups after 80 min under this field that have a difference in frequency showed that effects of frequency in behavior was meaningless.

  Conclusion: The results of this study showed that electromagnetic fields produce anti-stress effect in rats. The radio waves (A.W) have higher effects.


Mahin Kamali Fard, Raziyeh Alizadeh , Fahimeh Sehati Shafaei , Mortaza Gojazadeh,
Volume 10, Issue 1 (4-2010)
Abstract

  Background & Objectives :Prematurity is still one of the main causes of neonatal mortality and morbidity that makes a lot of financial, psychosocial and emotional problems.

  Although the main cause of preterm labor is unknown but understanding of its risk factors is important for planning health policies for preventing and decreasing the rate of preterm labor. This study aimed to compare lifestyle of women with term and preterm delivery.

  Methods :This research is a case-control study. Subjects of this study were 132 women with preterm labor and 264 women with term labor that referred to Educational and Medical Center of Alzzahra. The subjects were selected by convenience method and matched in age and educational level. Data were collected by questionnaire containing two sections, demographic characteristics and woman's lifestyle including,nutrition, exercise, smoking and use of alcohol and substance abuse, social support, stress management and self care. Data were analyzed by SPSS with descriptive statistics and statistical tests of t Test, Man Witny U, χ 2 and Fisher's Exact Test.

  Results : The results of this study showed significant differences in nutrition, smoking, use of alcohol, substance abuse, social support, stress management and self care between two groups, but the mean score of exercise in term and preterm birth was not statistically significant.

  Conclusion: The findings of our study suggest that there is a relation between lifestyle in pregnancy and preterm birth. Lifestyle is changeable and achieving this aim is possible by efforts to increase health education .


Mohammad Mazani , Shabnam Javadi , Jafar Bashiri , Abbas Naghizadeh, Amir Mansoor Vatankhah,
Volume 10, Issue 3 (9-2010)
Abstract

  Background and Objectives: Gastric cancer is the most incident disease in Iran that leads to death. This study was designed to evaluate the oxidative and antioxidative status in patients with gastric cancer by detecting paraoxonase 1 and arylesterase activities together with the level of malondialdehyde. The purpose of the present investigation was determination of Paraoxonase /Arylesterase activity and malondialdehyde (MDA) levels in the serum of patients with Gastric cancer.

  Methods: In a case-control study, 20 subjects who diagnosed as gastric cancer individuals that referred to Ardabil Aras Clinic were selected from 2008 up to 2009. The case groups were matched with control group (30 subjects). Arylesterase and paraoxonase activities of paraoxonase-1 (PON-1), MDA levels and lipid profile were determined spectrophotometrically in serum of subjects.

  Results: Upon matching of case and control groups, paraoxonase and arylesterase activities in patients with gastric cancer showed to be significantly lower than healthy subjects (190 ± 68.95 IU/L vs 258 ± 68.59 IU/L, 30.5 ± 28.4 U/L vs 284.23 ± 163.2 U/L respectively, P ≤ 0.001). Standardized activities of paraoxonase and arylesterase of case group were lower than controls (P ≤ 0.001). MDA levels have revealed significant increasing in cases than controls. In present study, HDL cholesterol and triglyceride levels were found to decrease in patient sera too, but the levels of total cholesterol and LDL cholesterol didn’t show to be different between two groups.

  Conclusion: It was concluded that in patients with gastric cancer, oxidative stress was raised by attenuation of antioxidant system and oxidant levels rising.


Farhad Pourfarzi , Afsaneh Enteshari Mogaddam, Abbas Yazdanbod , Zahra Tazakkori , Esmaeil Farzaneh , Mehrdad Mirzarahimi,
Volume 11, Issue 1 (4-2011)
Abstract

  Background & Objectives : Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is common through the world including Iran. Because of its chronic nature and lack of effective treatment, patients are always anxious and stressful and physicians are also exhausted of untreated patients. The cause of IBS is unclear and it has not effective treatment. Therefore, there is a need to find and introduce a proper method of treatment to control symptoms including abdominal pain and defecation changes. This study was aimed to determine the effectiveness of probiotic yogurt on the general relief of symptoms associated with IBS.

  Methods : Subjects were recruited from patients of gastroenterology clinic in Imam Khomeini Hospital, Ardabil. A total of sixty patients fulfilling the Rome II criteria took part in this study. Subjects were randomized into two groups of trial and control. Pre- and post- treatment symptoms were investigated using a questionnaire. Thirty one patients received probiotic and 29 patients normal yogurt for 4 weeks. Bottles of yoghurt were manufactured, and coded by a company. Both participants and researcher were blinded for the bottles' code. The symptoms were followed before and after two and four weeks of treatment and two weeks post- discontinuing of trial, too. Data were analyzed by SPSS (Ver. 17) and differences between groups were compared statistically using of chi-square and t-test.

  Results: A total number of 60 patients were recruited in this study of whom 36 (60%) were female and 24(40%) male. The average age of participants was 34.1±9 which did not differ between two groups. The onset of symptoms did not show any difference between two groups. The trial group had a history of 5.7±5.1 years while this was 6.5±4.9 for the controls. In overall, patients who were given probiotic yogurt had shown a better response in the control of abdominal pain and flatulence than those who were treated with normal yogurt. There was not a significant difference between two groups in the response to treat for other symptoms including epigastric pain, vomiting, frequency of defecation and feces consistency.

  Conclusion: According to our research, adding probiotic yogurt to the patient diet may help ease symptoms of IBS especially, abdominal pain and flatulence. Considering the high prevalence of irritable bowel syndrome and the lack of effective therapies, even a slight reduction in symptoms can have positive public health consequences.


Behnam Molaie , Mohammadali Mohamadi , Aghil Habibi , Vahid Zamanzadeh , Behrouz Dadkhah , Parviz Molavi, Naser Mozaffari ,
Volume 11, Issue 1 (4-2011)
Abstract

  Background and Objectives: The importance of considering to job stress among women is not related to loss of economics alone, but it makes an unsafe condition in health of body and soul of person, family and society, too. This study was aimed to determine the rate of job stress among employed women in Ardebil during 2010.

  Methods: In a descriptive cross-sectional study, 1250 governmental-employed women were selected in different offices of Ardabil city. Data were collected by job-contained Karasek questionnaire and results were analyzed by chi-square test.

  Results: The results showed that 62.8% of women experienced medium level of stress and 36.5% revealed to have severe stress. Our findings significantly showed that there are relationship between stress rate of individuals with number of children, level of education, place of living, job experience, rate of work hours per day and night work shift, employment status, physical and mental diseases (p <0.05 ( .

  Conclusion: With respect to severe stress found in employed women in study setting, it seems to need to increase mental health indices in individuals, families and community, and the authorities should develop a comprehensive plan to enhance productivity and satisfaction among employees.


Reza Mahdavi , Ali Nemati , Eiraj Feizi, Mojtaba Amani , Hosein Alimohammadi Asl, Mohammad Mazani M, Phd4; Nagizadeh Bagi , Abbas , Ali Shadman , Reza Alipanah Mogadam, Asghar Pirzadeh, Mousa Ghayour Nahand,
Volume 11, Issue 2 (6-2011)
Abstract

  Background & Objectives: Consumption of ω3 fatty acids supplementation inhibits oxidative stress injury, increases activity of antioxidant enzymes and decreases lipid peroxidation in gastric cancer patients. In this study, we examined effects of ω-3 fatty acid intakes on oxidative stress in gastric cancer patients undergoing chemotherapy.

  Methods: This double blind clinical trial study was conducted on 30 adult patients (15 cases and 15 controls) with gastric cancer during chemotherapy in Ardabil city in 2010. Case and control groups were selected by randomized allocation. Three grams ω -3 fatty acid supplementation (1.8 g EPA & 1.2 g DHA in 10 g fish oil) and placebo were given case and control groups for 45 days, respectively. Anthropometric indices (weight, height & BMI) were measured. Blood samples were taken and then biochemical factors including triglycerides, total cholesterol, HDL and LDL cholesterol, MDA, and total antioxidants were evaluated at the beginning, middle and end of the study . The data were analyzed by using Paired sample t-test, Independent sample t-test and repeated measures test.

  Results: MDA, Weight and BMI of omega group after intervention were significantly more than control group at the end of the study (p<0.05). Weight and BMI were decreased but serum MDA was significantly increased in control group during the study (p<0.05). Weight, BMI , and total antioxidants were significantly increased in omega group during day 30-45, (p<0.05). There were no significant differences in other biochemical factors at the end of study.

  Conclusion: The present investigation shows administration of ω3 fatty acid supplements to gastric cancer patients during chemotherapy increases the total antioxidants capacity and prevents the enhancement of oxidative stress.


Reza Alipanahmogadam , Mohammad Mazani , Abbas Naghizadeh Baghi, Ali Nemati, Mojtaba Amani , Bahman Bashardoost, Amir Mansour Vatankhah , Shahab Bohlooli,
Volume 11, Issue 3 (9-2011)
Abstract

  Background & Objectives: Several evidences show that oxidative stress is high among patients with hemodialysis . This study was aimed to investigate the oxidative stress and serum level of zinc and copper in patients with non-diabetic hemodialysis .

  Methods: In a case-control study, 60 patients with non-diabetic hemdialysis referred to hemodialysis section, Ardabil Bou-Ali hospital, and 60 healthy individuals, matched by age and sex, were selected. In each group, lipid profile, blood glucose, creatinine, urea, total protein, albumin, zinc, copper, malondialdehyde, total antioxidant capacity, activity of glutathione peroxidase and superoxide dismutase were measured. The results were analyzed statistically by using Pearson correlation coefficient and Student-t test.

  Results: The amount of zinc, blood sugar, cholesterol, triglyceride, total protein, albumin, high density lipoprotein-C and low density lipoprotein-C were significantly lower in patients with hemodialysis in comparison with those in normal individuals. T he activity of superoxide dismutase, glutathione peroxidase in red blood cells and serum total antioxidant capacity were significantly high in patients in comparison with those in control group. However, serum concentrations of copper and malondialdehyde in two groups were not statistically different.

  Conclusion : The results of this study show that increase of antioxidant enzymes activity reduces the oxidative stress status in patients with non-diabetic hemodialysis . Zinc deficiency was also observed in these patients.



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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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