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Showing 14 results for Quality of Life

Yousef Bafandeh , Davood Daghestani ,
Volume 6, Issue 4 (12-2006)

  Background & Objectives : Patients with esophageal SCC and GEJ adenocarcinoma have a poor prognosis. The advanced stage tumor is not amenable to cure and requires palliation, specially to relief dysphagia and to improve quality of life. Esophageal stenting has been shown to be faster, and longer lasting method of palliation. Esophageal expandable stents have been available recently in IRAN. The aim of this study was to report the results of our experience to relief dysphagia by means of stents, specially plastic removable types.

  Methods: This was a prospective trial in 60 patients with strictures due to malignant esophageal and /or GEJ cancers and those who had undergone anastomotic procedure during 2001 to 2005. These patients referred to endoscopy clinic of Tabriz Immam hospital for stenting. Dysphagia was scored according to a 5-point scale before stenting, 3 days after, and later during follow-up period of a mean of 7.6±6.6 months. Barium study and endoscopy was done for evaluation of site and length of stricture, and its etiology. Strictures were dilated up to 15 mm before stenting. The data were analyzed using correlation test, Chi-sqare and T- tests.

  Results: Covered metallic Wallstent was used in 12 patients removable covered polyflex stents in 47 and double lumen metal stent in only one case. Stents were successfully deployed in all cases. Dysphagia improved significantly by all stent types compared with the presenting status, after 3 days (p<0001) and during follow up period (p<0.05). Distal displacement of stents was seen in 16 (32%) patients, all of which happened during 1-3 months after insertion. In polyflex stents, the way restored by endoscopic intervention. Tumor overgrowth at the end of stent was seen in 4(8%) of the cases. Mean period of survival was 7.6± 6.6 months. In no case was the death directly attributable to the procedure.

  Conclusions: Self-expandable plastic stents (SEPS), have favorable efficacy in palliating dysphagia. Their insertion is easy, with low risk and successful and associated with a lower rate of complications, morbidity and mortality in majority of the patients.

Fariba Sadeghi Movahhed , Farideh Mostafazadeh, Mehrnaz Mashoufi ,
Volume 7, Issue 4 (12-2007)

 Background & Objective: Obsessive-compulsive disorder is a common disease in psychiatry which increases anxiety in approximately 2% of the world population. Recent reports suggest that OCD starts in menstruation, Pregnancy, post-partum periods which causes failure in women's quality of life. The aim of study was to determine the onset of (OCD) in fertile women.

 Methods: In a descriptive study in 2006, 53 women with DSM-IV were interviewed for obsessive disorder at psychiatry clinic of Fatemi hospital. A questionnaire including two parts on demographic information and 8 questions on the onset of obsessive disorder in menstruation, pregnancy, puerperium periods was completed. Data were analyzed through SPSS.

 Results: In 3.8%, the onset of obsessive disorder was with the first menstruation period. In 12.5% it was during pregnancy. In 57.1% (4) of obsessive samples onset of obsessive was in second pregnancy. In 16.24% onset of OCD was after delivery. In 28.8% it was after first delivery and 30% after first delivery had affective disorders.

 Conclusion: The menstruation, pregnancy, post partum may be a periods of risk for recurrence or onset of obsessive compulsive disorder and women should be taken care of more in order to avoid disorders like depression. Midwife clinicians caring for women need to be aware of the impact of these symptoms and attention for mental health in women.

Aghil Habibi, Soghra Neekpoor, Mahnaz Seyedolshohda, Hamid Haghani,
Volume 8, Issue 1 (4-2008)

Background & Objective: As life expectancy increases health promotion behaviours are even more important, particularly with regard to maintaining functional independence and improving quality of life (QoL). The purpose of this study was to explore the relationship
between health promotion behaviours and quality of life among elderly people in west region of Tehran.
Methods: This was a descriptive-correlational study. Through multi-stage sampling method, 410 participants over 60 years old and cognitively intact were selected to contribute in the study. The data-gathering tool consisted of a 2-part questionnaire Health Promotion Behaviour Checklist and Short Form Health Survey (SF12) that were used to measure QoL.
Results: The results of the study showed that there were statistically significant differences in QoL of the elderly related to 'exercise or walking and consumption of milk, dairy products, meat, vegetables and fruits and 'low salt diet', 'low fat diet', 'health check up', 'blood pressure (BP) (p< 0.05). The Elderly with high quality of life had more exercise or walking and consumption of milk, dairy products, meat, and fresh fruit and vegetables and the elderly with low quality of life, had better observed low salt diet, low fat diet, health condition control and blood pressure control.
Conclusion: Regarding the results we found that health promotion behaviours and the quality of life are related meaningfully, so, considering old people as a vulnerable group by health authorities, it is recommended to provide this group with programs and facilities to promote their health behaviours, social participation and to improve health care and provide consultation services.
Bita Shahbazzadegan , Rabiollah Farmanbar, Atefeh Ghanbari , Zahra Atrkar Roshan , Masoumeh Adib ,
Volume 8, Issue 4 (12-2008)

  Background & Objectives: With regards to the importance of health and Quality of Life improvement in the elderly in relation with physical activity and self esteem, the aim of this study was to determine the effect of programmed exercise on the self esteem of elderly residents in the nursing home of Rasht city in 2008.

  Methods: This study included a pretest and post test on 32 qualified samples. The Rosenberg self esteem scale were filled by them. Then, they attended a programmed exercise for one month. The scale was filled again by participants. The collected pre-test and pot-test data were analyzed using a-t-test SPSS software.

  Results: The average age of the participants was 73.53 (± 8.31). Most of them were widowed, 43.8% had no children, 87.5% were uneducated and the rest (12.5%) had a primary level of education. 37.2 of them had resided in the nursing home for less than one year and their average of residence was 1357±17.11 days. The source of income for 59.4% of participants was through children and relations. 27 persons (84.4%) had frequent visits with relations. 34.4% of them had a disease in history. There were significant correlations between number of children, marriage, education and job and number of previous jobs, gender job and education and number of previous job, visit frequency and education and time of the last visit. The correlation between sums of self esteem scores before and after the exercise was positive and significant and 22.81±4.84 Average of self esteem score before and after programmed exercise was 26.84±4.35.

  Conclusion: Regular exercise is effective in improving the self-esteem among the elderly and it can recommend to the elderly as a safe and cheap method.

Saeid Sadeghie Ahari , Solmaz Arshi , Manoochehr Iranparvar , Firouz Amani, Hosein Siahpoosh,
Volume 8, Issue 4 (12-2008)

 Background & Objectives: The prevalence of diabetes and its different methods of treatment have significantly been increased in the last two decades. The actual effect of these treatments is a common topic in the patients’ health and quality of life among these patients has a considerable importance in the community medicine. This study was designed to indicate the quality of life in the diabetic type II patients.

  Methods: This was a cross-sectional, descriptive analytic study in 2004 on 110 type 2 diabetic patients who had referred to Bu Ali Hospital in Ardabil. The patients were randomly selected and took the SF-36 Questionnaire and in the end the data were analyzed by SPSS.

  Results: The average age of the patients was 52.5 with the standard deviation of 11.3 years. 73 of the patients were female (66.4%) and rest of them were male. The average period of sickness among diabetics was 8 years from the time of diagnosis with a standard deviation of 6.2 years. The average of duration of therapy was 7.7 years with 6.1 years standard deviation. 51 patients (46.36%) had the history of hospitalization. Vitality indicator was low in 39.1% of patients. Social functioning was low in 50% of patients. In general, by adding up the quality of life’s various indexes scores based on SF-36 questionnaires standard coefficients, 77% of patients had intermediate and low quality of life.

  Conclusion: According to this study most of the patients in this study had a low quality of life.

Maryam Namadi , Asiyeh Movahdpoor,
Volume 9, Issue 2 (6-2009)

  Background and objectives: Quality of life is an important aspect in the evaluation of different therapeutic interventions. Quality of life assessment helps to find patients problem and revise their therapeutic method. The purpose of this study was to evaluate the life quality among patients receiving renal transplantation in comparison with hemodialysis in Ardabil university of Medical Sciences.

  Method: In this comparative study a total of 70 patients with renal transplantation and 93 hemodialytic patients were chosen through census sampling. An interview based questionnaire was administered for subjects to gather information on demographic characteristics and kidney disease quality of life scale.

  Results: Findings show that, 65.7 percent of transplanted patients reported their quality of life as good. While, in 65.6 percent of hemodialytic patients life quality was moderate. The average quality of life score in transplanted patients was 95.44 ± 12.44 SD while it was 83.53 ± 14.89 for the patients under dialyzes. The difference between the two groups were significant (p< 0/001).

Conclusion: It is concluded that by transplantation, the life quality of in CRF patients may be improved.
Amir Mohammad Asnaashari , Hasan Ghobadi Moralou, Shahrzad Mohamadzadeh Lari , Elham Ghalenoei ,
Volume 10, Issue 3 (9-2010)

 The OHS is characterized by hypersomnolence, hypoxia, polycytemia, headache and edema. Polysomnography is the gold standard diagnostic test. Overnight oximetry with significant oxyhemoglobin desaturation is reasonable to begin treatment. Weight reduction and Non invasive positive pressure ventilation (NIPPV) has evolved as the mainstay of treatment.

 Obesity is a risk factor for deep vein thrombosis (DVT). Heparin and warfarin are the drugs that used for treatment of DVT. HIT typically appears as a 50% or greater reduction in the platelet count after the first exposure to heparin. This case is a obese man with extreme DVT that diagnosed by duplex sonography and symptoms of obesity hypoventilation syndrom.

 In overnight pulseoximetry oxyhemoglobin desaturation was occurred more than 15 times per hours and treatment begins with NIPPV. Patients thrombosis were treated with heparin and warfarin. Heparin induced thrombocytopenia (HIT) and cutaneous necrosis was occurred and drug therapy withdrawn. After healing of cutaneous necrosis low dose warfarin was started.

 NIPPV promote airway occlusion and improve hypercapnia.hypoxia and quality of life and reduced cardiovascular complications.

Babak Nakhostin-Roohi, Nasrin Vaezi ,
Volume 11, Issue 3 (9-2011)

 Background & Objectives: Effects of new educational programs on health and physical fitness promotion is an important issue which needs regular evaluations. Physical fitness has many advantages such as cardio-respiratory health promotion, prevention of some diseases and improvement of quality of life. On the other hand, it has been shown that there is significant relationship between waterpipe smoking and cancer, cardiovascular as well as pulmonary diseases. The aim of this study was to evaluate the relationship between addiction to waterpipe smoking and cardio-respiratory fitness and body composition of physical education students in Islamic Azad University, Ardabil Branch.

 Methods: One hundred and eighty-one physical education students participated in this study. All subjects were selected by cluster sampling method. Cardio-Respiratory fitness (using Cooper test), Body Mass Index (BMI), Fat percent (using 2-point Lohman equation), addiction to waterpipe smoking, smoke exposure and awareness of waterpipe effects on athletic performance (using questionnaire) were evaluated.

 Results: The body composition of the most students was not suitable (50.3% extra fat), but the cardio-respiratory fitness of male students was better than that of female students.

 Furthermore, In spite of decrease in waterpipe smoking in comparison to last year (13.3% versus 35.6%), many non-smoking students are exposed to waterpipe smoke (21.0%) and some of them (48.1%) had little information about the harmful effects of waterpipe smoking on athletic performance.

 Conclusion: According to results of this study improvement in cardio-respiratory fitness and body composition of physical education students and enhancement of their information about side-effects of waterpipe smoking should be emphasized

Bahman Bashardoost , Shahram Habibzadeh, Anahita Zakeri , Neda Ghaemian ,
Volume 12, Issue 5 (11-2012)

  Background & Objectives: Cardiovascular events are the most common cause of death in hemodialysis patients. Cardiac biomarkers and especially Cardiac troponin I has been used as a prognostic marker in hemodialysis patients and there is some controversies about its value. For these reasons this study has been done for evaluation of prognostic value of Troponin I and left Ventricular Hypertrophy in mortality of hemodialysis patients.

  Methods:This is a prospective descriptive-analytic study, has been done from 2006 -2011 All of new cases whom entered to dialysis center in 2006 studied with measurement of base line Cardiac Troponin I and left ventricular mass index .Patients fallowed up 5 years later without any specific intervention and survival rate was calculated crudely and in base of Cardiac Troponin I and left ventricular mass index separately after exclusion of non cardiac deaths.

  Results:76 patients followed up 5 years and 35 of them died. Mean age of patients was 57.4 ± 15.6 year. Mean Troponin I (cTnI) in dead patients was 0.92±0.68ng/l and in alive patients was 0.78±0.58ng/l (p=0.39). Mean Left Ventricular Mass in dead patients was 274.9±100.8 g/m2 and in alive patients was 249±77.7 g/m2 (p=0.23). A significant linear correlation was not founds between cTnI level and Left Ventricular Mass Age was the most important cofactor of death.

  Conclusion: Significant correlation was not founded between cTnI level and Left Ventricular Mass with cardiac mortality .mortality. This may be due to some other factors such as age, quality of control of hypertension and other coexisted diseases, quality of life and home cares. Age had more important effect on death and this may reflect multiplicity of heath related problems in them.

Yousef Shafaiee, Vahid Sadeghifard , Bita Shahbazzadegan ,
Volume 14, Issue 3 (9-2014)

  Introduction: Complete Amputation of wrist is physical and psychological trauma that can affect person's life. During recent years, various amputated organs were replanted back into their own body leading to improvement in quality of life, function and body image.

  Case Report : The case was a34 years old man with complete amputation at left hand at wrist level, while working with chainsaw. Patient was admitted to the emergency unit at Fatemi hospital of Ardabil city, and underwent tosurgery for replantation.

  Conclusion: Complete amputation of wrist and its successful replantation are among rarely occured and reportable cases . The5 -month follow-up indicated a successful operation . During this period, no abnormalities were found in the blood circulation . The finger grasping and nerve development were acceptable and no symptom of infection was observed

Mahdi Saadati , Mahdokht Taheri , Mohammad Hadi Bahadori ,
Volume 14, Issue 4 (12-2014)

  Background & objectives : Infertility is a global problem affecting millions of men and women in developed and developing countries. In this regard, in-vitro fertilization (IVF) plays an important role in improving the quality of life in infertile patients. However, studies have shown that the implantation failure in IVF is the main challenge of this procedure. Melatonin can increase the survival rate of embryos and IVF success rate through eliminating free radicals and removing reactive oxygen species. So, this study is conducted to investigate the effects of different concentrations of melatonin on the rate of newborns of mice following transfer oftwo-cell embryos .

  Methods : In this study, female mice with average age of six to eight weeks were superovulated by administering pregnant mares serum gonadotropin (PMSG) intraperitoneally (7.5 IU. ip), and followed after 48h by human chorionic gonadotropin (hCG) (7.5 IU. ip). Two-cell mouse embryos were obtained from female mice oviduct after 48 h. The embryos transferred bilaterally into pseudopregnant mice of the same strain through surgical procedure and 8-14 embryos were transferred to each tube. The study included 4 treatment groups and one control group (6 mice in each group). The treatment groups were exposed to subcutaneous injection of concentrations of 100 µm , 10 µm , 1 µm and 100 nm of melatonin. After the cesarean on 18th day of pregnancy, the percentage of live births was assessed. The outcomes of the live birth rate were as­sessed using the chi-square test and statistical analyses were carried out using SPSS version 16.0. Percentage of live birth was calculated and compared with the control group.

  Results: A total of 701 two-cell mouse embryos were transferred into one control group and four experimental groups. The number and percentage of live births at concentrations of 100 µm and 10 µm of melatonin and the control groups were 21 (15.55%), 13 (9.15%) and 9 (6.47%), respectively. No infant was born at the concentrations of 1 µM and 100 nM of melatonin . The highest rate of live births was obtained at the concentration of 100 µM and showed a significant difference with the control group (p ≤ 0.01). There was no significant difference in live births at the concentration of 10 µm and control group.

  Conclusion : The results of this study indicated that subcutaneous injection of melatonin improves the two-cell mouse embryo growth and post implantation development of mice.

B Zamani, M Azari, A Hosseinian , A Shokrdargahy, A Mardi , Sh Azari,
Volume 15, Issue 2 (6-2015)

Background & objectives: Myocardial infarction (MI) isone of the most commonly heart diseases in all countries with the mortality rate of about 30%. Reperfusion of blocked coronary arteries plays an important role in reducing mortality and enhancing the quality of life of patients after acute MI. 

Methods: This clinical trial is to compare the efficacy of streptokinase administered intravenously in a two slow and accelerated groups: control group (slow intravenous infusion during 1 hour) and case group (half-hour accelerated intravenous infusion of streptokinase) with the sample size of 100 patients (divided randomly to 50 patients in each group). The data tool was a questionnaire, included the collected ECG changes before and after echocardiography and laboratory tests of patients. Data analyzed with SPSS software using chi-square test. 
Results:After reperfusion of the coronary artery, in the both case and control groups, elevation of ST segment has decreased statistically in two groups (60% and 84%, respectively). The complications rate following injection of SK in both case and control groups were 46% and 56%, respectively. The fraction in which 30% and 38% belong to cardiac complications, 32% and 22% to allergic symptoms and hematologic effects were 32% and 22%, in two groups, respectively and there was no statistically significant difference between two groups. 
Conclusion:According to the results of this study the accelerated (30 minutes) SK infusion can be fruitful for improving coronary reperfusion in patients with MI.

Arezo Samadi Bilehsavar , Shabnam Nohesara, Mohammadreza Najarzadegan, Parviz Molaei , Kaveh Alavi, Amirhossein Nadoushan ,
Volume 17, Issue 1 (4-2017)

Background & aims: The main purpose of this study was to investigate the impact of NEO personality dimensions on general health, quality of life and job burnout in a sample of faculty members of Iran University of Medical Sciences.

Methods: In this correlational study, data were collected by convenience sampling using General Health Questionnaire (GHQ), WHO Quality of Life- Brief (WHOQOL-FFI), Maslach Burnout Inventory (MBI) and NEO-FFI. In order to analyze the data, statistical indices, including mean, standard deviation and Pearson correlation coefficient were used. 

Results: The results showed a significant correlation between  personality dimensions, including  neuroticism, extraversion, conscientiousness and agreement with any public health variables (correlation coefficients 0.435, 0.533, 334.513, 0.0) and quality of life (correlation coefficients 0.294, 0.438, 312.459, 0.0) and burnout (correlation coefficients 0.259, 0.351,       -0.302, -0.299, 0.0) , respectively in the Department of Surgery, but openness to experience had  no significant correlation with any of the above-mentioned variables. Also, there was a significant relationship between the three variables of public health, quality of life with burnout.

Conclusions: According to the findings, it can be concluded that in the participants of this study, increase of neuroticism scores was associated with decreased general health and quality of life scores and increased job burnout. Further, increased extroversion scores were associated with increase in general health and quality of life and decrease in job burnout scores.

Hasan Ghobadi, Somaieh Matin, Ali Nemati, Hasan Javadi , Reza Alipanah-Moghadam , Mehdi Saeidi-Nir ,
Volume 19, Issue 1 (4-2019)

Background & objectives: Chronic Obstructive Pulmonary Disease (COPD) is accompanied by systemic inflammations and is characterized by irreversible airflow limitations. Leptin is a cytokine with pre-inflammatory effect. However, there have been no studies on the effect of conjugated linoleic acid (CLA) on the serum leptin concentration in COPD patients. Therefore, the present study aimed to explore the effect of CLA on the serum leptin level, lung function and quality of life in COPD patients.
Methods: This interventional study was conducted on 90 COPD patients. The patients were randomly divided into two groups (supplement and placebo) with 45 patients per group. After obtaining written consent from the patients and recording their demographic characteristics, the spirometry was performed and COPD assessment test (CAT) score was calculated. Moreover, a fasting blood sample was collected from each of them in order to analyze their serum leptin concentration. After that, the patients in the supplement group were administered with 3.2 g/day of CLA for 6 weeks. The patients in another group received placebo. After the intervention, spirometry, CAT score calculation and blood sampling were repeated for all of the patients and the obtained results were analyzed.
Results: after the intervention, a significant decrease both in the serum leptin level and in CAT score as a quality life marker  was observed in the supplement group (p<0.05). Moreover, the FEV1 levels as a lung function test, increased significantly in the supplement group after the intervention (p<0.05). Although, the difference between the two groups was not significant.
Conclusion: The use of CLA supplement can improve COPD patients’ quality of life through decreasing the serum level of leptin in their blood.

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