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Showing 4 results for Migraine

Maziyar Hashemilar , Nayereh Aminisani , Darioush Savadi Oskoui , Mahzad Yosefian ,
Volume 4, Issue 1 (4-2004)
Abstract

 Background & Objective: Studying the epidemiology and impact of headache can help improve patient care, estimation of burden of disease and classification systems. Migraine is common worldwide and has a geographically variable prevalence in the world. Moreover, its peak of incidence is the age of 20-30. The aim of this study was to determine the prevalence of migraine among the medical students in order to plan for future health interferences.

 Methods: In this cross-sectional study 631 students filled out a questionnaire designed according to the criteria of the international headache society. The data were analyzed using SPSS software (release 12) and descriptive statistics.

 Results: 76.6% of the subjects were female and 23.4% of them were male. The females were 20.6 and males were 21.4 years old on average. The total prevalence of migraine was 7.3% (1.6% with aura, 5.4% without aura and 0.3% with both of them). Moreover, females, single subjects and students of medicine, except the migraine with aura that was more prevalent among students of associate degrees. A positive family history of headache was found in 45.6% of the students. 65.2% of those suffering from migraine had not referred to a physician and were unaware of their headache.

 Conclusions: Compared to similar researches there is a low prevalence of migraine among the students but most of the students do not take measures to cape with and treat them in the proper manner. This requires necessary health interferences.


Mehrdokht Mazdeh , Mansoor Nazari ,
Volume 8, Issue 2 (6-2008)
Abstract

  Background & Objective: Migraine is one of the chronic and Common Kinds of headache. Among important treatments which are advised for improvement of acute migraine attack, there are tryp tans and Ergot Alkaloids Because of side effects of Ergot Alkaloids Like nausea, vomiting, lack of appetite, Peripheral vessel contractions and induced headache and its limited consumption and patients age limitation, the patients face some difficulties using Ergot Alkaloid. On the other hand Tryp tans are Consumed as a monotherapeutic regimen but Ergot Alkaloids must be used with metoclopramide in order to prevent nausea and also they should be used in the acute phase of migraine so we decided to Compare the two groups of drugs so that if they have positive effectiveness in favor of Tryp tans, using them would be advised.

 Methods: The range of age for patients was 20- 40 years who suffered from classic and common migraine according to IHS criteria, were randomly placed in two groups. One group (36) was treated in the acute phase of disease by sumatryptan and the other (39) by a combination of 3 dihydroergotamine and naproxen and metoclopramide, and therapeutic effectiveness was studied by three Criteria of intensity, attack and frequency of attack. After the treatment, they were analyzed through chi square.

 Results: In terms of intensity, duration and frequency of the headache after the treatment, there was no significant difference between two groups and the results in both group were the same.

 Conclusion: As there were no significant statistical difference between the effect of two drugs on attack intensity, headache duration and frequency in patients of classic and common migraine, and because of the complications of Ergot Alkaloids like vomiting it should be consumed with metoclopramide and because of vessels contractions which may result in the organs gangrene and induced headache, and its maximum dose is 6 mg per week, sumatryptan is advised as the monotherapeutic.


Ghazaleh Ghamkharnejad , Parviz Shahabi, Mina Sadighi, Behnaz Sadeghzadeh,
Volume 14, Issue 1 (4-2014)
Abstract

  Background & Objectives : Cortical spreading depression (SD), a self-propagating depolarization of neuroglial cells, is believed to play a role in different neurological disorders including epilepsy and migraine aura. A brief period of excitation heralds SD which is immediately followed by nerve cell depression and later by prolonged excitation. The aim of the present study was to investigate relationship between SD and late phase of excitability and seizure burst activity inlateral amygdale of rat.

  Methods: Male Wistar rats with 250-350 gram body weight were used. We usedamygdale slices taken from Wistar rats. SD was induced by KCl. After superfusion of these slices with sub-epileptic concentration of bicuculline for 45 min, the induction of SD in the lateral amygdale resulted in presence of interictal and ictalepileptiform field potentials.

  Results: After initiation of SD in lateral amygdale, glutamate receptors (NMDA, AMPA) antagonists as well as K+ and Ca++ channels blockers were able to decrease the amplitude of excitatory postsynaptic potentials.

  Conclusion: The results imply a possible role for SD in temporal lobe epilepsy in predisposed neural tissue with increased excitation or decreased inhibition. The study of the late phase of SD excitability may help us to understand the mechanism of SD action in associated neurological disorders. This finding may improve the therapeutic strategies for treatment of epilepsy.


Sevda Parsa, Davar Altafi ,
Volume 14, Issue 3 (9-2014)
Abstract

  Background &objections: Migraine is the second most common cause of headache in15% of women and 6% of men. Migraine headaches areperiodic and usually with unilateral and throbbing quality,and often accompanied by nausea, vomiting, phonophobia, photophobia and malaise. Approximately 15-20% of migraine attacks start with visual aura or other neurological symptoms. So far there isn’t accurate and practical diagnostic test for this patients and diagnosis is based on clinical features and other causes. The aim of this study was to investigate the role of visual evoked potential (VEP) in patients with common and classic migraines and t effects on the electrophysiology of visual system and understanding pathophysiology in neurological symptoms.

  Methods: In this study, 44 migraine patients, including 28 patients with common and 16 patients with classical migraines admitted to neurology private clinics from January to June 2013 in Alavi hospital of Ardabil city and16 healthy volunteers (control group) were used. Mean wave, P100 Latency and P100-N140 Amplitude were compared and determined between three groups.

  Results: The mean latency of P100 migraine group was significantly higher than healthy people. Average P100-N140 amplitude of migraine group was fewer than the control group, and the mean P100-N140 amplitude was more common than classical group.

  Conclusions: Despite differences in results of VEP tests, VEP can be used as an adjuvant test in the diagnosis of migraine, as well as a confirmation for distinguishing common and classical migraine and can be used as a tool in determining the severity of migraine and/or a parameter for its electrophysiological effects. However, more detailed studies are needed in this area .



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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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