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Showing 2 results for Middle Cerebral Artery (mca)

Saeid Khamnei , Nahid Ghandchilar, Hooshang Najafi, Mahdi Farhoudi,
Volume 6, Issue 1 (4-2006)

 Background & Objectives: Many researches have been conducted on autoregulation of cerebral blood flow (CBF), but its possible variations coincidence with postvagal tachycardia have not yet been studied. The present study searched for the effect of this phenomenon on CBF in young and middle-aged persons.

 Methods: 52 healthy volunteers including 13 young males (mean age 23.9±0.8), 13 young females (mean age 24.2±0.7), 13 middle-aged males (mean age 58±0.9) and 13 middle-aged females (mean age 56.4±0.7) went under the study. Flow velocity in middle cerebral artery (MCA) was assessed using transcranial Doppler (TCD) ultrasonography apparatus. Eckberg’s neck suction device was utilized to stimulate carotid baroreceptors. The data were analyzed using Minitab and SPSS software (rel. 10).

 Results: Concomitant to the carotid baroreceptors stimulation there was a significant reduction in heart rate in all groups (p<0.05), but mean cerebral blood flow did not change significantly. After ending the carotid baroreceptors stimulation and concomitant to PVT, mean cerebral blood flow increased in all groups except middle-aged males. This increase in CBF became significant in middle-aged females (p<0.05).

 Conclusion: The results of the present study indicate that cerebral blood flow autoregulation act effectively concomitant to acute stimulation of carotid baroreceptors and this efficacy is maintained until the middle-age, but when faced with PVT, cerebral blood flow autoregulation dose not act effectively.

Manoucher Iranparvar, Davar Altafi, Bahman Mohammadzadeh,
Volume 17, Issue 3 (10-2017)

Background & objectives: Diabetes mellitus is the sixth leading cause of death in individuals older than 25 years, and accounts for %18 of all deaths. The aim of this study was to investigate the TCD findings in diabetic patients with a history of less and more than 5 years.
Methods: In this descriptive, analytic study, all diabetic patients were divided into two groups based on the duration of diabetes, less and more than 5 years after diagnosis. TCD was performed on the patients, and maximum velocity and mean pulsatility index and resistivity index in the right and left Middle Cerebral Arteries (MCAs) and basilar artery were measured. The checklist was completed for all patients, and all data were analyzed by SPSS (v16) statistical software.
Results: Sixty four percent of the patients with duration less than 5 years (average age of 55.16 years) and 36 percent of those with duration more than 5 years (average age of 59.37 years) were men. There was no statistically significant difference between disease duration and Body Mass Index (BMI), but with an increase in duration of disease, HbA1C of patients was increased. There was no significant difference between the velocity of right, left and basilar arteries and diabetes duration. Also, there was a significant difference between diabetes duration and pulse index of right MCA and basilar. There was no significant difference between age, BMI and HbA1C and pulse and resistivity indexes among patients.
Conclusion: In this study abnormal pulse and resistance indexes in patients with duration more than 5 years was more than patients with less than 5, this may indicate the effect of diabetes duration on the vascular wall.

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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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