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Showing 3 results for Iodine Deficiency
Mahdi Hedayati , Parvin Mirmiran, Parta Hatamizadeh , Hamid Jafavizadeh , Rambod Hajipour , Fereidoon Azizi ,
Volume 6, Issue 3 (9-2006)
Background and Objectives: Iodine deficiency disorders have been one of the main health-nutritional problems in Iran for many years. Prior to the iodine-supplementation program, Ardabil province was one of the regions with endemic goiter in Iran. The program of control and prevention of iodine deficiency has been performed here since 1989 through production, distribution and consumption of iodized salt. This study was performed in 2001 on 7-10 years-old pupils of Ardabil as a part of national monitoring survey of iodine deficiency control.
Methods: In a cross sectional- descriptive study, 1200 students (equal number of boys and girls) were selected randomly. The prevalence of goiter was determined by clinical examination and according to WHO classification. Urinary iodine content was determined in one tenth of the cases using digestion method.
Results: Total goiter rate was 9.3 in all the subjects (10.7% in girls and 7.9% in boys). Median urinary iodine was 18.8µg/dl. In 80.7% of the cases urinary iodine was above 10µg/dl and was less than 5µg/dl in 4.2%. Urinary iodine below 2µg/dl was not observed.
Conclusion: The results showed that the rate of goiter among pupils has significantly decreased since 1996 and urinary iodine levels in schoolchildren of Ardabil complied with WHO index. So, Ardabil province can be considered as an “iodine deficiency free” zone.
Soltanali Mahboob, Majid Mohamad Shahi , Abolhasan Shakeri, Alireza Ostad Rahimi , Seyedjamal Ghaem Maghami , Fatemeh Haidari,
Volume 7, Issue 2 (6-2007)
Background & Objectives: Goiter prevalence in school age children is an indicator of the severity of iodine deficiency disorders (IDDS) in the society and a goiter prevalence ≥5 % in school age children indicates a public health problem. In area of mild to moderate IDDS, measurement of thyroid volume by ultrasonography through observation is preferrable to population for grading goiter. Considering the importace of this issue, because of being mountainous and lack of this method's application for determining the incidence of goiter this study was desinged.
Methods: In this descriptive – analytical study, thyroid volumes of 230 boys between 12 to 15 years old were measured by portable ultrasonograph in Tabriz. Also urinary iodine concentrations were determined by method A (Sandell-kolthoff reaction).
Results: Mean of subjects’ thyroid volume was 8.12 ±2.21 ml and with latest references of Iran and WHO/NHD, goiter prevalence was taken based age 51.7 % and based surface body 81.1 %. Urinary iodine median of tested samples was 15.2µg/dl and iodine deficiency prevalence was 29.1 % . There was no significant correlation between urinary iodine and thyroid volume.
Conclusion: Large thyroid volume of middle school boys in Tabriz is probably due to iodine intake deficiency in the first years of their life. Also, the role of goitrogenic factors and effect of climate condition on thyroid volume and goiter prevalence of middle school boys in Tabriz shouldn't be ignored. Further studies are recommended for determination of a local reference for thyroid volume Also it is necessary to be sure from consumption of iodine salt and its standardization.
Seyedeh Hooriyeh Fallah, Narges Kalantar, Seyedmahmood Mahdinia, Neda Taheri, Nooshin Babaei,
Volume 8, Issue 1 (4-2008)
Background & Objective: Iodine deficiency is one of the most important life-threatening factors from the beginning and encounter irreversible damage to human. This study aimed to investigate stability of Iodine in iodized salt in different situations such as light and humidity and comparing it with standard amounts.
Methods: In this cross-sectional descriptive-analytical study, 12 samples of iodized salts which have been distributed in Damghan, were accidentally selected. Samples were examined in the chemistry laboratory of Faculty of Health (Damghan University of Medical Sciences) using titration method recommended by British pharmacopeh. 10 mg of each iodized salts were kept at presence of light, darkness, humidity, and non- humidity situation and then titration method was performed. The samples were kept for two weeks and examined weekly. Data were analyzed with T paired and ANOVA tests using SPSS software.
Results: Findings of this study showed that reduction of Iodine was seen for all samples. The amount of reduction were 2.2, 1.5, 4.1 and 2.1 mg/l for purified salts at light, darkness, humidity, and non- humidity situation, respectively. The amount of reduction were 3.4, 2.1, 5.35 and 2.6 mg/l for non-purified salts at light, darkness, humidity, and non- humidity situation, respectively. In spite of reduction in Iodine, concentration of it was at standard amount (30-50 PPM).
Conclusion: Results showed that stability of iodine was more when salt was exposed to darkness in comparison with light situation (p< 0.09). Meanwhile, the stability of purified salts was more than the non- purified salts (p< 0.28). Also, stability of iodine was less at humidity in comparison with non- humid situation (p< 0.006). The purified salts which was exposed to humidity was much stable compared to the non- purified salts (p< 0.28). It also, demonstrated that the amount of iodine stability was more for salts which was exposed to light in comparison with humidity (p< 0.05).