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Showing 7 results for Sadeghieh Ahari

Saeid Sadeghieh Ahari , Ahad Azami , Manoocher Barak, Firooz Amani , Seddigh ,
Volume 4, Issue 2 (Summer 2004)

  Background and objectives: Establishing centers to stop addiction in our country is one of the measures taken to confront this problem. Unfortunately, it has been shown that about 80% of the addicted people who refer to these centers relapse. The present study set out to investigate the possible causes of this problem.

  Methods: This is a case control study in which a questionnaire was used to collect the required data. The subjects were all addicted people who referred to Shahid Mellat Doust and Shahid Family treatment centers in 2000. The criterions for entering the study in case group were the last record of the addicted person ’ s abandonment in Tehran ’ s welfare center ( based on the patients ’ records) and using narcotics at the present time. The control group subjects, on the other hand, had abandoned using narcotics at least four months before and had never used any substance so far.

  Results: The mean age for case group was 35.99 and that of the control group was 35.09. Regarding the age distribution 98.59% of the case group and 100% of the control group were men. 88.7% of the case group and 97.2% of the control group were urban residents. Considering the job, 40.8% of the case group and 19.4% of the control group were unemployed. 52.1% of the case group and 61.6% of control group were living with their spouses. Opium was the most commoly used narcotics in both groups. In studying the relationship between the variables under study through logistic regression the job was not a main factor in the relapse. The duration of time being away from addiction had a deductive effect on the relapse, and this effect was statistically meaningful (p=0.001). Adding one month ’ s time to the period of being clear (not using the narcotics) caused 98% deduction in returning to narcotics.

  Conclusion: Because 80% of the patients who referred to the related centers began using narcotics again during the first 6 months after abandoning, it is necessary to improve the preventive measures to help the patients pass this critical period.

Adalat Hosseinian, Saeid Sadeghieh Ahari, Hosein Dostcami , Sooreh Sheikham ,
Volume 7, Issue 2 (Summer 2007)

  Background & Objectives: Mitral valve prolapse (MVP) syndrome is one of the most prevalent abnormalities of mitral valve that arises from pathologic changes of the various parts of mitral valve. MVP may lead to ECG changes, like T wave inversion in inferior leads and atrial and ventricular arrhythmias, in some people that may be misdiagnosed as myocardial ischemia.

  Methods: This was an analytical (case-control) study in 50 cases with MVP with age below 30 years who had referred to the Ardabil Bouali Hospital and some private cardiology clinics. The diagnosis of MVP was based on clinical and echocardiographic findings, and after taking history and physical examination, an ECG and an echocardiogram were taken from each person in case and control groups and the acquired information was analyzed via statistical methods of SPSS software.

  Results: From 50 studied cases with MVP, 60% (30 cases) were female and 40% (20 cases) were male, and the most common age range was 21 – 25 years. From these cases, 68% (34 persons) had changes in their ECGs while %32 (16 subjects) did not. In control group, from 50 persons, 44% (22 persons) had ECG changes and 56% (28 persons) did not.

  Conclusion: In general this study showed that increase in ECG changes in MVP group in comparison with control group (p=0.01). In cases with MVP, there was not significant relationship between gender and ECG changes. In comparing case and control groups, there was not significant difference in ECG changes in females, while there was a significant difference in males (14 of 20 versus 6 of 20) w ith considering that ECG changes in persons with MVP may be misdiagnosed as ischemic heart disease,it is recommended that cases (especially men) with MVP always keep a record of their ECGs.

Manoochehr Barak , Saeid Sadeghieh Ahari , Firouz Amani , Gholamreza Asadi, Gity Rahimi , Elham Khadem,
Volume 12, Issue 5 (suppl 2012)

  Background & Objective: Currently, migration of rural population to cities and developing slums around them are main problems in population settlement that lead to imbalance in health standards such as difference in age groups death. The aim of this study was to examine factors associated with infant mortality in slums of the Ardabil city.

  Methods: This was a case- control study. All infants’ deaths from 2008 to 2010, which occurred in slums as a case, were included. For each case, tow controls, were chosen. Controls the ones who survived and were living in non marginalized area and years of birth and sex were matched in two groups. Information collected from health centers through questionnaires, interviews with parents and child death files.

  Results: The majority of mortalities (74.6%) were in neonatal period and 25.4% was in post- neonatal period. The most important causes of deaths in neonatal were prematurity (57%), and in post neonatal period were congenital abnormality (35.4%). Analysis of effective factors showed that birth weight, parents age and education, family income and occupation and smoking of father were highly associated with mortalities.

  Conclusion: Infant mortality of the family that their father is a smoker and they have low income, and low parental education level is significantly higher and should be taken into serious consideration to reduce the mortality.

Mostafa Nachvak , Sheida Ahani Kamangar , Ali Nemati , Saeid Sadeghieh Ahari ,
Volume 14, Issue 2 (summer 2014)

  Background & Objectives: Epidemiological and experimental evidences suggest that oxidative stress is elevated in children with Down syndrome (DS). Some studies show that consumption of diets with a high content of fruits and vegetables results in a significant reduction in markers of oxidative stress. We investigated the frequency of fruits and vegetables intake in children with DS and the influence of variations in the level of this consumption on biomarkers of oxidative stress .

  Methods: Frequency of consumption of fruit and vegetables by children with DS were recorded by interview with the children’s parents. Serum malondialdehyde (MDA) and urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) were also measured as biomarkers of oxidative stress. Data analysed using ANOVA and Student’s t-tests .

  Results : Mean consumption of fruits and vegetables was 4.6 and 0.74 servings per week, respectively. No significant relationships were found between consumption of fruits and vegetables with markers of oxidative stress. Based on our findings, the 65.9 % of the children did not eat any vegetables and the rest of the children consumed less than one serving per day. There was a significant correlation between the frequency of fruits and vegetable consumption (r=0.212 p <0.04).

  Conclusion : There wasn’t any significant relationship between fruits and vegetables consumption and indicators of oxidative stress in children with DS. This lack of correlation could be due to low consumption of fruits and vegetables in children with DS.

Faramarz Hosseinzadeh, Saeid Sadeghieh Ahari , Ali Mohammadian-Erdi ,
Volume 16, Issue 2 (summer 2016)

Background & objectives: One of the most proven trajectories for analyzing the drug consumption patterns in the community is to assess the prescriptions. Using the antibiotics for prevention and treatment of infectious diseases not only leads to the loss of pathogens but also causes various complications, the most important of which is the drug resistance. The aim of current study was investigating the different antibiotics prescript by general practitioners (GPs) for outpatients in Ardabil city.

Methods: This study is designed based on the cross-sectional method. The number of 2,000 copies (according to Morgan) from total of 526000 copies sent to Ardabil health insurance during the 4 seasons of 2013 were randomly evaluated. The collected data were analyzed by descriptive statistics, ANOVA and T-Test using spss software. The P ≤0.05 was considered statistically significant.

Results: In this study the average drug per prescription was 3.6 and 54.9% of the prescriptions included antibiotics so that the cefixime, azithromycin, Co-amoxiclave and penicillin 6.3.3 were the most frequently prescribed antibiotics, respectively. The highest prescriptions belonged to penicillins (39.4%) cephalosporins (27.7%) and macrolides (18.3%). The most expensive antibiotic was cefixime tablet (32% of the total cost). The most of the antibiotics were prescribed to be taken orally (tablets or capsules). The mean price of each prescription was 74539±71050 Rials. The highest rate of antibiotic prescription was related to the autumn and then winter and there was a significant relationship between the the number of antibiotics in different seasons of the year (p = 0.005).

Conclusion: The average drugs of each prescription are in accordance with local statistics, but much higher than the global figures. The frequency of antibiotics prescription was higher than the global, several Middle Eastern and even African countries’ indices but was lower than the average level of some regions in the country. The pattern of prescribing antibiotics among the Ardabil GPs shows the more drugs in number and expensive broad-spectrum. The average price of prescripts was higher than the national average. These findings suggest that prescription and using antibiotics is not desirable in Ardabil.

Hasan Edalatkhah, Nazila Rahnema Tareghi , Saeeid Sadeghieh Ahari , Ali Nemati,
Volume 17, Issue 2 (summer 2017)

Background & objectives: Acne Vulgaris is a chronic inflammation of pilosebaceous glands. Some studies have indicated the significant decrease of linoleic acid in the sebum composition of the patients with acne. The aim of this study was to determine the probable therapeutic effects of linoleic acid on moderate acne.
Methods: In a double-blind randomized clinical trial, 40 women with moderate acne were divided into two groups, each group with 20 each with 20 samples. After recording the nutritional and demographic factors, the case group received, 100 mg oral doxycycline daily plus 3 gr conjugated linoleic acid and the control group received 100 mg doxycycline daily plus 4-3 oral paraffin capsules as placebo for one month. The number of acne lesions were counted before and after treatment and the mean of   Acne Severity Index (ASI) and Global Acne Grading System (GAGS) were determined for each group. The collected data were analyzed by SPSS software using chi-square, independent t-test and paired t-test.
Results: The mean age was 22.8±5.5, in the case group and21.7±5.1 in placebo group indicating no statistically significant deference (p=0.51). At the end of treatment there was no statistically significant deference between the two groups in decreasing acne (p=0.31). During the treatment, ASI reduced from 129.5±13 to 77±11.6 in the case group and from 132±18.6 to 67.5±11.6 in the placebo group, –but there was no statistically significant deference between the two groups (p=0.37).
Conclusion: It seems using 3 gr oral conjugated linoleic acid daily for 1 month has no effect on remission of acne.
Hasan Edalatkhah, Zahra Bironbar Fathi , Negar Khoshnevis , Saeid Sadeghieh Ahari ,
Volume 18, Issue 2 (summer 2018)

Background & objectives: In recent years, the hypothesis of using anti-androgens has been increasingly addressed in the treatment of acne in women. One of these drugs is flutamide, which there is no strong evidence of its efficacy in treatment of acne in women. The aim of this study was to compare the effect of combination therapy of flutamide-cyproterone compound with flutamide-doxycycline in severe type of acne in women.
Methods: In an interventional study, patients were divided in to two groups. One group (n=30) received flutamide - cyproterone compound and another group (n=30) received flutamide-doxycycline which were followed for six months. Both groups also received 1% topical clindamycin twice a day. Counting the number of lesions, changes in severity index and grading of acne were used to evaluate the patients. Patient satisfaction was also evaluated.
Results: The mean age in the flutamide-doxycycline group was 19.4±4.67 and in the flutamide-cyproterone compound group was 19.06±11.3. This difference was not statistically significant. The mean of the acne severity index at the onset of intervention between the two groups was not significant (p= 0.7). The mean of the acne severity index at the start of treatment in the flutamide-doxycycline group was 306.07±155.46 and at the end of treatment reached to 19.18±19.5, and also in the flutamide-cyproterone compound group, decreased from 293.21±15.21 to 10.5±21.8 at the end of treatment. This difference was not statistically significant (p=0.1).
Conclusion: Both therapeutic regimen were effective in the treatment of severe type of acne and can possibly be used as an alternative treatment for severe acne.

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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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