Background and Objectives: Oxidative stress has a role in the pathogenesis of type II diabetes due to increase in insulin resistance or disorder in insulin secretion and atherosclerosis. Food antioxadants including carotenoids protect against diabetes by preventing oxidation reactions. Therefore, this study was conducted in Sabzevar to study the relationship between carotenoids and blood sugar and lipids in type II diabetic patients.
Methods: This cross-sectional analytical study was conducted on type II diabetic patients who were randomly sampled. Their height and weight were measured and relevant data on nutritional intake and frequency in 3 successive days were collected through 24-hour recall. Measures were domesticated and converted to grams. Carotenoids of the intakes were calculated. Blood sugar, triglycerides and serum cholesterol after 12 hours fasting were measured through enzymatic procedures. Data analysis was carried out by descriptive statistics and partial correlation.
Results: 75 type II diabetic patients with mean age of 54.05±14.2 years, mean BMI of 27.02±5.03 Kg/m2 participated in the study. Their mean blood sugar, triglyceride and cholesterol were 196.36±87.82, 262.84±147.89 and 243.98±60.76 mg/dl respectively. Mean daily intake of beta carotene was 1236.56±810.21 mcg, alpha carotene 878.170±149.04 mcg, lutein 1163.40±819.77 mcg, zeaxanthin and lycopen were 2195.77 ±988.70 mcg.
Conclusion: Our results showed that most carotenoids negatively correlated though not significantly with their blood sugar and lipids.