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Showing 14 results for Iranparvar

Manoochehr Iranparvar, Abbas Yazdanbod , Firooz Amani, Shabnam Sohrabi ,
Volume 3, Issue 3 (Autumn 2003)

  Background & Objective : Palpable thyroid nodules are found in almost 5% of the adults. Regarding the high prevalence of this condition, recognizing and evaluating them are important for physicians. Fine Needle Aspiration (FNA) is the first easy and cost-effective way for recognizing pathologic nature of the nods. The present research was an attempt to investigate the epidemiology and evaluate the pathological findings among patients using FNA.

  Methods : This is a descriptive study conducted on all 145(113 female and 32 male) patients referring to the endocrinology clinic of Ardabil in the period between October 1999 to October 2002. The data were collected using a questionnaire, the physical examination of the patients, noting down the clinical finding, doing FNA and its report presented by a pathologist. The data were then analyzed with descriptive statistics and frequency tables using SPSS software.

  Results : Most of the patients (36.5%) were 30-40 years old. FNA of 115 patients (79.4%) was reported as benign and that of 6 patients (4.1%) was malignant, 16 patients (11%) had a doubtful FNA, and in 8 patients (5.5%) the sample was not enough. Among patients with benign FNA, 102 cases (70.6%) had nodular goiter, 8 cases (5.5%) had colloid cyst, 3 cases (2%) had follicular adenoma and 2 cases (1.3%) had thyroiditis. Among patients with malignant FNA 1 case (0.7%) had follicular carcinoma and 5 cases (3.4%) had papillary carcinoma.

  Conclusions : The results indicated that most of the malignant lesion is papillary carcinoma, which has a lower prevalence compared to similar studies. Regarding the higher prevalence of thyroid carcinoma in middle ages it seems necessary to investigate the thyroid nodules in this age- group.

Seyedhashem Sezavar , Leili Abbaszadeh , Adalat Hosseinian , Manoochehr Iranparvar , Minaye Khodamoradzadeh ,
Volume 3, Issue 3 (Autumn 2003)

 Background & Objective: Hypertension and diabetes mellitus coexist more commonly than predicted by chance and the synergistic effect of these two diseases is the cause of early disability and high rate of mortality in these patients. Controlling the blood pressure has a critical role in decreasing cardiovascular mortality in diabetic hypertensive cases. The goal of this study is to determine the rate of recognition and treatment of hypertension in type II diabetic subjects referring to diabetes clinic of Bou-ali hospital, Ardabil.

 Methods: In this cross-sectional study 300 type II diabetic patients were examined in terms of blood pressure control.

 Results: The patients who participated in this study ranged between 28 to 80 years of age (mean: 55.5 ± 11.4). About 61.6% of diabetic patients had hypertension (BP>140/ 90 mmHg) 76.7% of these patients were aware of their hypertension. Only 8.8% of these patients with hypertension had a well-controlled blood pressure and the rest of them (91.2%) had a poorly- controlled blood pressure (BP>130/80 mmHg). About 21.8% of hypertensive diabetics although aware of their hypertension were not on any anti- hypertensive agents.

 Conclusions: This study indicates poor control of hypertension in diabetic patients. It seems that reconsidering CME programs for the physicians, emphasizing the control of risk factors especially in high-risk groups and educating the diabetic patients will improve the control of hypertension in these patients.

Abbas Yazdanbod , Manoochehr Iranparvar, Solmaz Seifi ,
Volume 4, Issue 3 (Autumn 2004)

  Background &Objectives: According to a recent report published by the Ministry of Health in Iran gastric cancer is the most common cause of death due to cancer in this country and cardiac cancer is the most common kind of upper GI cancer. This study is an attempt to determine the epidemiology of cardiac cancers in Ardabil.

  Methods: This descriptive cross-sectional study was conducted for four years (2000-2003) at the only private clinic in Ardabil. The results of endoscopy of these patients including the exact determination of the topography of cancer in cardia and other general information were recorded. The data were analyzed using SPSS software (version-10)

  Results: During this study 4356 endoscopy were done and 533 histologically proven upper GI cancer were detected. Out of 533, 242 cases were located at E-G junction area, 82(33.9%), 130 (53.7%) in cardia region and 30(12/4%) cases were located at the proximal bady of stomach. 130(53.7%) cases of tumors were, in the right side of cardia. Bormann classification showed that most of cancers (43.8%) were ulceroinfiltrative.

  Conclusion: Statistical analysis indicated that there is a significant relationship between type and topography of cancer with dysphasia, weight loss and epigasteric pain(p<0.05). The results showed significiant relationship between type and topography of cacers with Bormann classification(p=0.001). Further epidemiologic studies are required to evaluate etiology of cardia cancers in Ardabil.

Eabbas Yazdanbod, Fateme Samadi, Reza Malekzade, Masuood Babaie , Manoogehr Iranparvar , Ahmad Azami ,
Volume 5, Issue 2 (Summer 2005)

  Background & Objectives: Recent studies in Ardabil province indicated that upper GI cancer is the most common kind of cancer in this province. Due to the lack of any study concerning the survival rate of the patients in this province, the present research set out to evaluate the effect of demographic features of GI cancers, risk factors, histopathology type, the site of tumor and treatment on the survival rate of these patients.

  Methods: In this descriptive-analytical and prospective study, we followed up 420 upper GI cancer cases (141 esophagus cancers and 279 stomach cancers) who were initially diagnosed in the only subspeciality GI clinic of Ardabil province during four years from 2000 to 2003.

  Results: The information related to 299 patients was recorded. The dates of death of 55 cases were found referring to the provincial death registration program while the addreses of 67 cases were not found. The 1-4-year survival rates in the patients with upper GI cancer in Ardabil province were 25.9%, 11.1%, 4.5% and 1.8% respectively. In this study men had a lower survival rate than women and patients with esophagus cancer had a longer survival rate. In the patients with stomach cancer "Signet ring cell type" histopathology had the lowest survival rate. The patients who had undergone surgery survived longer than other patients with no resectional surgery treatment. Histopathology grading, age at first diagnosis, positive familial history of GI cancer, as well as cigarette, alcohol and opium consumption had no effect on survival rate of these patients.

  Conclusion: Overall survival rate of our patients is very low this condition might be related to late diagnosis and less treatment facilities in Ardabil province.

Saeid Sadeghie Ahari , Solmaz Arshi , Manoochehr Iranparvar , Firouz Amani, Hosein Siahpoosh,
Volume 8, Issue 4 (Winter 2008)

 Background & Objectives: The prevalence of diabetes and its different methods of treatment have significantly been increased in the last two decades. The actual effect of these treatments is a common topic in the patients’ health and quality of life among these patients has a considerable importance in the community medicine. This study was designed to indicate the quality of life in the diabetic type II patients.

  Methods: This was a cross-sectional, descriptive analytic study in 2004 on 110 type 2 diabetic patients who had referred to Bu Ali Hospital in Ardabil. The patients were randomly selected and took the SF-36 Questionnaire and in the end the data were analyzed by SPSS.

  Results: The average age of the patients was 52.5 with the standard deviation of 11.3 years. 73 of the patients were female (66.4%) and rest of them were male. The average period of sickness among diabetics was 8 years from the time of diagnosis with a standard deviation of 6.2 years. The average of duration of therapy was 7.7 years with 6.1 years standard deviation. 51 patients (46.36%) had the history of hospitalization. Vitality indicator was low in 39.1% of patients. Social functioning was low in 50% of patients. In general, by adding up the quality of life’s various indexes scores based on SF-36 questionnaires standard coefficients, 77% of patients had intermediate and low quality of life.

  Conclusion: According to this study most of the patients in this study had a low quality of life.

Manoochehr Iranparvar, Fathemeh Ghannadi-Asl,
Volume 9, Issue 3 (autumn 2009)

  Background & Objectives: Adherence to a diabetic diet is one of the most important aspects of diabetes management. Compliance with a diabetic diet has usually been described in terms of total intake. We examined indexes of the use of specific foods that would normally be either recommended or prohibited by Food Frequency Questionnaire.

  Methods: In order to study the dietary habits of the patients with type II diabetes 228 outpatients with type II diabetes referring to Ardabil Diabetic Clinic were randomly selected.

  Results : A common diabetic diet was reported by 87.8% of women (N = 115) and 77.1 % of men (N = 74). The dietary habits of the patients showed their awareness of limiting use of simple sugars. Use of foods with high simple sugars (e.g.: honey, jam, soft drink) were low among the patients. Potato was consumed by 58.8% of the female and 74.2% of the male, and of 43.8% of the subjects used mulberry with tea.

  Conclusions: Our result showed that there should be a greater focus on counseling, education and improving dietary of patients with diabetes.

Manoochehr Iranparvar Alamdari, Hosein Ghorbani Behrooz, Abbas Yazdanbood, Naiyereh Amini Sani , Solmaz Islam Panah, Mahmood Shokrabadi,
Volume 12, Issue 3 (autumn 2012)

  Background & Objectives: Diabetes Mellitus is a metabolic disorder in which lacking of control and suitable care lead to disability and mortality. American Diabetes Association (ADA) has emphasized the medical care of diabetic patients and has suggested several objectives to increase survival and improve health outcomes with low complications by controlling the glycemic, lipids, nerupathy and hypertension as well as foot care, nutritional therapy and screening of cardiovascular disease. The aim of this study was to evaluate the quality of care in diabetic patients from Ardabil and its concordance to the standards recommended by ADA.

  Methods: In a cross sectional study, 100 diabetic patients referring to a clinic of diabetes in Ardabil (2005) were randomly selected and enrolled.

  The study was conducted according to a questionnaire with 90 questions and physical examination and Final lab tests. Data were collected and analyzed with Spss version 12. ANOVA test was used to compare groups.

  Results: The 12 months recorded lab tests for diabetic patients were as follows: Hb A1C in 33%, MicroAlbuminuria in 16%, HDL in 58% and LDL in 55% of patients had been checked. Foot and peripheral pulses exams were only recorded in 9 and 5% of patients respectively. In final lab tests, 24% of patients had favorable FBS level (90- 130mg/dl). 46% of patients had suitable Hb A1C and 32% patients had MicroAlbuminuria. Aspirin was recommended to 45% of patients over 50 years old.

  Only 10% of patient for three lab tests (FBS, LDL cholesterol, Hb A1C) achieved the intended aims. According to ADA recommendations 22% of patients for three risk factors (BP, LDL cholesterol & Total cholesterol) were in optimal level.

  Conclusion: There is a high difference between current diabetes care in our clinic and ADA goals.

Akbar Atadokht , Mohammad Narimani, Batool Ahadi, Abbas Abolghasemi, Adel Zahed , Manoocher Iranparvar,
Volume 13, Issue 2 (summer 2013)

  Background & objectives: Diabetes mellitus is a common metabolic disorder that has negative effect on physical function, psychological condition, interpersonal, family and social relationship and in general, on psychological well being. The aim of this study was to investigate of psychological profile in diabetic patients and it's relatioship with social support.

  Methods: In this descriptive-correlational study, 120 diabetic patients have been selected among of those that systematically refered to Diabetes Clinic of Emam Khomeini Hospital in order to follow their therapeutic process in Ardabil . Data gathering was accomplished by two tests: SCL-90-R and Social Support Scale. Finally data were analyzed by Pearson correlation coefficient and T-test on SPSS-17 software and p-value less than 0.05 considered as significant.

  Results: Results showed that 70% of diabetic patients had problems in somatic complaint and obsession, 62.5% in sensitivity, 72.5% in depression, 62.5% in anxiety, 55% in hostility, 67.5% in paranoid thoughts, 27.5% in phobia and 37.5% in psychosis. Correlations between social support with somatic complaint, obsession, sensitivity, depression, anxiety, hostility and paranoid thoughts were negatively significant. Family support associated significantly with all of the psychological variables but friend Support had no significant correlation with them.

  Conclusion: The range of psychological problems experienced by diabetic patients is more extensive and these problems have significant relationship with social support. Thus, attention to different dimensions of psychological health is necessary and social support-based interventions can be more effective.

Touraj Rahmani , Farid Bahrpeyma, Manoochehr Iranparvar , Mohammad Taghikhani ,
Volume 14, Issue 3 (Autumn 2014)

  Background & objectives: Type 2 diabetes mellitus results in vascular dysfunction and reduction of nitric oxide (NO) level. In this study the effect of electromagnetic field (EMF) on NO level, an effective factor in increasing blood flow, and on ankle brachial index (ABI) as a n index of lower extremity blood flow in type 2 diabetic patients, have been investigated.

  Methods: This study was a randomized controlled clinical trial carried out in Imam Khomeini hospital of Ardabil and Mehr physiotherapy center in 2013. Thirty diabetic patients after initial pilot study participated in this experiment based on inclusion and exclusion criteria. Then, they were randomly assigned into two equal groups, electromagnetic therapy and control. The baseline levels of ABI and NO of both groups were measured. Patients in electromagnetic group were exposed to 10 Hz EMF radiation (with intensity of 8 mT) together with scanning lower limbs (three sessions per week, and 40 minutes per session for 8 weeks). The control group did not receive any treatment. After eight weeks, the amount of ABI and NO level were recorded. For statistical analysis paired t-test and independent t-test were used in SPSS 19 software.

  Results: Statistical analysis showed significant differences between pre (1.009±0.02) and post (1.052±0.02) measurement of ABI of diabetic patient after applying magnetic field ( P = 0.013). However, there was no significant difference between p and after measurement of ABI and NO level in controlgroup and also NO level in magnet groups ( P> 0.05). Difference between pre and post therapy of ABI in electromagnetic group (0.05±0.01) showed significant increase compared with control group (0.004±0.003) ( P = 0.001).

  Conclusion: Increase in ABI after 8 weeks electromagnetic therapy could be considered as an accretion index in blood flow in lower extremity.

J Ataei , Sm Shamshirgaran, M Iranparvar Alamdari , Ar Safaeian,
Volume 15, Issue 2 (summer 2015)

 Background & objectives: Successful implementation of diabetes care can reduce acute and chronic complications of diabetes. This study was conducted to evaluate the quality of care according to a care scoring system among people with type 2 diabetes referring to the diabetes clinic in Ardabil.

 Methods: This cross sectional study was conducted in 2014 and a total of 300 people with type 2 diabetes in age range of 20-70 years old were included via convenience sampling. Data were collected by an interviewer using a structured questionnaire and checklist. Each patient was classified according to a quality of care scoring system into 3 categories: ≤10, 15-20, >20. Statistical analysis performed by SPSS v.20 software and descriptive analysis used to display data as frequency tables and graphs. Analytical tests such as ANOVA, Kruskal-Wallis, Chi squared, and fisher exact test were also used to analyze the data.

 Results: The mean age of patients was 54.13 ± 9.13 and the majority of them were women (72.3%). The mean of BMI and HbA1c was 29.58 ± 4.77 and 8.93± 2.13, respectively. The mean of FBS was 191.18 ± 84.23 and the average length of disease was 7.74±5.89 years. The mean of quality of care score among participants was 23.20±9.99. About one-third of patients (29.7%) had a quality care score ≤10, half of them (51%) had a score between 15-20, and only 19.35% had a score >20. There was an association between HbA1c, FBS, diastolic blood pressure, cholesterol and LDL with a quality of care score which was statistically significant (p<0.05).

 Conclusion: In this study there was a gap between the current quality of care of patients and recommended standards. Therefore in order to minimize the current barriers and problems it is recommended to implement an effective interventional program. In addition, using a quality care scoring system is a rapid, easy and valid method for evaluating diabetes quality of care.

Manoucher Iranparvar, Davar Altafi, Bahman Mohammadzadeh,
Volume 17, Issue 3 (autumn 2017)

Background & objectives: Diabetes mellitus is the sixth leading cause of death in individuals older than 25 years, and accounts for %18 of all deaths. The aim of this study was to investigate the TCD findings in diabetic patients with a history of less and more than 5 years.
Methods: In this descriptive, analytic study, all diabetic patients were divided into two groups based on the duration of diabetes, less and more than 5 years after diagnosis. TCD was performed on the patients, and maximum velocity and mean pulsatility index and resistivity index in the right and left Middle Cerebral Arteries (MCAs) and basilar artery were measured. The checklist was completed for all patients, and all data were analyzed by SPSS (v16) statistical software.
Results: Sixty four percent of the patients with duration less than 5 years (average age of 55.16 years) and 36 percent of those with duration more than 5 years (average age of 59.37 years) were men. There was no statistically significant difference between disease duration and Body Mass Index (BMI), but with an increase in duration of disease, HbA1C of patients was increased. There was no significant difference between the velocity of right, left and basilar arteries and diabetes duration. Also, there was a significant difference between diabetes duration and pulse index of right MCA and basilar. There was no significant difference between age, BMI and HbA1C and pulse and resistivity indexes among patients.
Conclusion: In this study abnormal pulse and resistance indexes in patients with duration more than 5 years was more than patients with less than 5, this may indicate the effect of diabetes duration on the vascular wall.
Manoucher Iranparvar, Bahman Bashardust, Shadab Mirfakhrayi,
Volume 17, Issue 3 (autumn 2017)

Background & objectives: Diabetes mellitus belongs to a group of common metabolic disorders characterized by hyperglycemia phenotypes. Diabetes mellitus causes secondary pathophysiological disorders in multiple organs of the body such as nephropathy, which causes many problems for patients and the health care system. In this study, the effect of pentoxifylline, a nonselective phosphodiesterase inhibitor, on reducing urinary protein excretion in diabetic patients was assessed.
Methods: In this clinical trial, 72 diabetic patients with proteinuria who were admitted to the endocrine and nephrology clinic were selected and divided into two groups. Checklists, including demographic data, etc. were completed. In group (A), Angiotensin-converting enzyme inhibitors (ACEI) or Angiotensin II receptor blockers (ARBs) were prescribed to reduce proteinuria, and in another group (B), in addition to ACEI or ARB drugs, pentoxifylline was prescribed. In the end, the results in both groups were compared in terms of further reduction of proteinuria.
Results: Most of the studied patients were male. There was a significant correlation between proteinuria (mean urinary protein excretion in 24 hours) and the effect of pentoxifylline on reducing proteinuria in patients with type II diabetes. Also, there was not a significant difference in systolic and diastolic blood pressure changes and HbA1c between the two groups at the beginning and end of the study.
Conclusion: Pentoxifylline, independent of lowering blood pressure or reducing the improvement of metabolic control, can significantly decrease proteinuria and protein excretion
Asghar Mahmoudi, Marefat Siauhkouhian , Manoucher Iranparvar, Hasan Anari, Farnaz Seifi,
Volume 17, Issue 4 (winter 2018)

Background & objectives: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world which is associated with cardiovascular disease. The aim of this study was to investigate the plasma changes of chemerin and pentraxin-3 (PTX3) following 8 weeks of endurance training in men with NAFLD.
Methods: In this quasi-experimental Study, thirty four patients with NAFLD were selected purposefully. The participants were randomly divided into two groups, endurance training group (n=17) and control group (n=17). The endurance training program included eight weeks running on a treadmill with maximum heart rate (HRmax) intensity of 55-75% for 45 minutes three times a week. Seventy two hours before the beginning of the study and at the end of the eighth week, blood samples were taken from all the participants. The data were analyzed by paired sample t-test and independent t-test at the significant level p<0.05.
Results: Plasma levels of chemerin in the endurance training group significantly decreased (p=0.013). Also, there was a significant difference between the two groups after the end of the intervention (p=0.002). Plasma levels of PTX3 increased significantly in the endurance training group (p=0.001). There was also a significant difference between two groups after the end of the intervention (p=0.01).
Conclusion: The present study showed that the 8-week endurance training increased the plasma levels of PTX3 and decreased the plasma levels of chemerin in men with NAFLD. Endurance training, possibly through various mechanisms, reduces the inflammatory factors and increases the anti-inflammatory factors in men with NAFLD. Endurance training, probably by activation of lipolysis, over-regulation of unpaired protein-1 and activator receptors of peroxisomes proliferation-, changes in adipocytokines, etc. decreases charmicin and increases PTX3 levels of plasma in men with NAFLD.
Asghar Mahmoudi, Marefat Siahkouhian, Manouchehr Iranparvar, Hassan Anari,
Volume 19, Issue 1 (spring 2019)

Background & objectives:  with Regard to the increasing prevalence of nonalcoholic fatty liver disease (NAFLD), focusing on various strategies for its prevention and management seem necessary. The purpose of this study was to investigate the effect of running on treadmill and low calorie diet on visfatin and hs-CRP values in people with NAFLD.
Methods: In this quasi-experimental Study, 55 NAFLD patients were selected and randomly assigned to one of four groups: training (n=14), diet (n=14), training plus diet (n=14) and control (n=13). The training program included eight weeks running on a treadmill with maximum heart rate intensity of 55-75% for 45 minutes three times a week. A low calorie diet with an energy deficit of 500 calories of daily energy intake was calculated from 3-day food records of the patients. Combined group subjects also used both types of intervention. Data were analyzed using covariance analysis and Bonferron's post hoc test at a significance level of p<0.05.
Results: Visfatin values in the training group (p=0.01), in the combined group (p=0.001) and also hs-CRP values in the training group (p=0.003) and the combined group (p=0.008) decreased significantly. The body mass index of subjects was significantly decreased by training (p=0.003) and combined intervention (p=0.001).
Conclusion: Running on treadmill and a low calorie diet simultaneously reduce the plasma levels of visfatin and hs-CRP in male patients with NAFLD. Therefore, these therapeutic interventions are beneficial in reducing NAFLD inflammatory factors.

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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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