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Showing 29 results for Hosseini
Effat Mazaheri , Seyedhashem Sezavar , Adalat Hosseinian , Nasrin Fooladi ,
Volume 2, Issue 4 (Winter 2002)
Background & Objective : Today, with changes in health care systems, most of the patients, receive occupational and special cares at home after being discharged from hospital . The aim of this study was to assess the effects of follow up on physical and emotional status of the patients with recent myocardial Infarction .
Methods : This experimental study was done on 60 patients with acute myocardial infarction, who referred to Boali Hospital during 2000-2001.The patients were chosen randomly and were set in two different groups with 30 subjects in each group . Then, a home care program was designed for case group. but there was no intervention for control group . This home care program was completed and one week later the physical and emotional status of the patients in two groups were analyzed by Spilbergar and Beck tests and finally the results were compared in two groups using X2 test.
Results : The X2 test showed that there is a significant difference between resting heart rate of two groups with P<0.05 but the difference among systolic and diastolic blood pressure, body weight, anxiety and depression was not statistically significant in two groups.
Conclusions: Regarding the effects of follow-up on the physical and emotional status of the patients, nurses can improve the quality of the patienys life through active home - care and rehabilitation programs along with social supports.
Adalat Hosseinian , Seyedhashem Sezavar , Mohammadtaghi Nikneghad , Farid Ghosseili, Zahra Mussavi , Eilnaz Mohammadi ,
Volume 3, Issue 2 (Summer 2003)
Background & Objective: Despite all improvements in diagnosis and treatment, one third of patients with Myocardial infarction lose their life. Different studies have shown that cardiac arrhythmia are the most common cause of death in MI, and cardiac blocks are one of the important groups of these arrhythmia, which are effective in prognosis, duration of hospitalization and hospital mortality of the patients.
Methods : In this study, 630 patients with AMI, who were admitted in CCU of Bou-Ali hospital in Ardabil from January 1998 to January 2001 were studied and the data were callected with the help of questionnaires and secondary data analysis method. The data were analyzed with statistical methods.
Results : 9.4% of cases in this study had AV block and 30.2% had bundle branch block. 40.5% of men and 37.6% of women had at least one kind of block(in AV node or bundle branch), but no significant relation was found between sex and these blocks. Also, 62% of in-hospital mortalities of patients with AMI were in association with blocks (AV or bundle branch) and only 38% of mortalities were without blocks. This showed a meaningful relation between hospital mortality and these kinds of blocks (p <0.05 ).
Conclusions: The total frequency of AV and bundle branch blocks due to AMI, was 39.6% which is similar to other studies, but what is remarkable in this study, is the higher prevalence of bundle branch blocks due to AMI.
Seyedhashem Sezavar , Leili Abbaszadeh , Adalat Hosseinian , Manoochehr Iranparvar , Minaye Khodamoradzadeh ,
Volume 3, Issue 3 (Autumn 2003)
Background & Objective: Hypertension and diabetes mellitus coexist more commonly than predicted by chance and the synergistic effect of these two diseases is the cause of early disability and high rate of mortality in these patients. Controlling the blood pressure has a critical role in decreasing cardiovascular mortality in diabetic hypertensive cases. The goal of this study is to determine the rate of recognition and treatment of hypertension in type II diabetic subjects referring to diabetes clinic of Bou-ali hospital, Ardabil.
Methods: In this cross-sectional study 300 type II diabetic patients were examined in terms of blood pressure control.
Results: The patients who participated in this study ranged between 28 to 80 years of age (mean: 55.5 ± 11.4). About 61.6% of diabetic patients had hypertension (BP>140/ 90 mmHg) 76.7% of these patients were aware of their hypertension. Only 8.8% of these patients with hypertension had a well-controlled blood pressure and the rest of them (91.2%) had a poorly- controlled blood pressure (BP>130/80 mmHg). About 21.8% of hypertensive diabetics although aware of their hypertension were not on any anti- hypertensive agents.
Conclusions: This study indicates poor control of hypertension in diabetic patients. It seems that reconsidering CME programs for the physicians, emphasizing the control of risk factors especially in high-risk groups and educating the diabetic patients will improve the control of hypertension in these patients.
Nader Pashapour, Mohamaad Hosein Hosseinianzakaria,
Volume 5, Issue 1 (spring 2005)
Background & Objectives: Yogurt is recommended as a treatment for acute diarrhea. This study was conducted to determine the effect of pasteurized yogurt consumption on acute non-bloody and non-mucoid diarrhea in hospitalized 6-24 month old infants as compared with that of routine treatment.
Methods: In a clinical trial study 80 children with 6 to 24 months of age with diarrhea for less than four days and were hospitalized in Urmia Imam Hospital, were assigned into two groups. The first group consumed yogurt containing streptococcus thermophilus and lactobacillus bullgaris 5 ml/kg per day while the second group received the routine treatment. Those suffering from malnutrition, bloody stool and diarrhea without GI source were excluded. Reduction of diarrhea frequency to half compared to admission time was regarded as response to treatment. Weight gaining, duration of admission and reduction of diarrhea frequency were compared in two groups.
Results: The two groups were not significantly different in terms of age, weight and frequency of diarrhea at the time of admission. Mean hospitalization days, weight gaining, reduction of diarrhea frequency were 2.7±0.91 days, 435± 89.30 grams, and 4.30±1.74 times respectively for case group and, 3.1± 0.74 days, 383 ± 98.96 grams, and 3.60±1.23 times for control group respectively. No significant differences were observed between two groups regarding mean hospitalization days (P=0.035), reduction of diarrhea frequency (P=0.049) and weight gain (P= 0.017).
Conclusion: Consuming pasteurized yogurt as a probiotic agent has a positive effect in treatment of acute nonbloody and nonmucoid diarrhea. Public use of yogurt is recommended.
Hosein Doostkami , Adalat Hosseinian, Gholam Hosain Fatehi,
Volume 6, Issue 1 (spring 2006)
Background & Objectives: Coronary artery diseases are the leading causes of mortality and morbidity in industrial countries and in Iran. Myocardial infarction and unstable angina are essential clinical syndromes of coronary artery diseases, with the difference that the mortality and morbidity of NonST-elevated myocardial infractions is more than U/A and requires more intensive care. Rapid differentiation and diagnosis of NSTEMI from U/A plays a major role in effective treatment of patients and improvement of their prognosis. This study was designed to determine the incidence of nonST-elevated MI among patients hospitalized with initial diagnosis of U/A.
Methods: This is a descriptive and analytical study performed on patients hospitalized with U/A diagnosis between 2001 and 2002 in Ardabil Buali hospital. The data (including demographic characteristics, patients’ clinical findings, ECG changes, laboratory findings) were collected using a questionnaire and analyzed by SPSS software using descriptive and analytical statistics.
Results: mean patient age was 61 and prevalence of nonST-elevated MI among patients with U/A was 23 patients (22.1%). Mean age of patients with NSTEMI was 60.5 and its prevalence was greater in male (69.9%) than in female (30.4%). The most prevalent ECG change in patients was T wave inversion and ST depression (78.3%) and in U/A patients it was T wave inversion (60.5%). The difference was statistically significant (p<0.001). 64.7% of the NSTEMI patients and 27.4% of the patients with U/A had severe chest pain (p<0.004).
Conclusion: Prevalence of NSTEMI was about 1/5 of patients hospitalized with diagnosis of U/A and ECG changes among these patients (as T wave inverison and ST depression along with negative T wave) is more prevalent compared to those with U/A. Clinical manifestation and complications were more severe in these patients than U/A group.
Adalat Hosseinian , Shahram Habibzadeh , Saeid Sadegieh Ahari , Akbar Mokhtarpoor,
Volume 7, Issue 1 (spring 2007)
Back grounds and objectives : Arthrosclerosis is the major cause of cerberovascular disorders and major problems of industrial countries. Mortality from chronic diseases such as arthrosclerosis and mortality from infectious diseases have a reverse, relationship with economic and educational levels of people. For this reason, investigating the relationship of MI with other risk factors such as infections has been of great interest.
Methods: This was a case- control study. 60 patients with MI and 60 matched cases were selected from other wards of Boali Hospital. All of the patients who had been admitted with myocardial infarction diagnosis in the time of study were selected and information about them was recorded in a researcher made questionnaire. Serum sample from patients and control case were sent to determinations of IgG Anti Chlamydia antibodies with enzyme immune assay. Control case were selected from other wards of hospital who matched in age, sex and same test in serum sample was done.
Results: In this study in each group 48 persons (80%) were male and 12 persons (20%) were female. The range of age group was 35-80. Mean age group was 58.83±12.6 (SD) and mean age of control tools was 59.08±11.59.All of the patients in each group had anti Chlamydia antibodies (IgG) (titer more than 5U/ml). The mean range IgG in both groups were compared through t-test and there was no significant difference between them (p=0.85).
Conclusion: In this study all of the cases and controls had anti Chlamydia antibodies. (IgG) high prevalence due to cold climate and high crowd of people in this area may be related to Chlamydia infection.
Adalat Hosseinian, Saeid Sadeghieh Ahari, Hosein Dostcami , Sooreh Sheikham ,
Volume 7, Issue 2 (Summer 2007)
Background & Objectives: Mitral valve prolapse (MVP) syndrome is one of the most prevalent abnormalities of mitral valve that arises from pathologic changes of the various parts of mitral valve. MVP may lead to ECG changes, like T wave inversion in inferior leads and atrial and ventricular arrhythmias, in some people that may be misdiagnosed as myocardial ischemia.
Methods: This was an analytical (case-control) study in 50 cases with MVP with age below 30 years who had referred to the Ardabil Bouali Hospital and some private cardiology clinics. The diagnosis of MVP was based on clinical and echocardiographic findings, and after taking history and physical examination, an ECG and an echocardiogram were taken from each person in case and control groups and the acquired information was analyzed via statistical methods of SPSS software.
Results: From 50 studied cases with MVP, 60% (30 cases) were female and 40% (20 cases) were male, and the most common age range was 21 – 25 years. From these cases, 68% (34 persons) had changes in their ECGs while %32 (16 subjects) did not. In control group, from 50 persons, 44% (22 persons) had ECG changes and 56% (28 persons) did not.
Conclusion: In general this study showed that increase in ECG changes in MVP group in comparison with control group (p=0.01). In cases with MVP, there was not significant relationship between gender and ECG changes. In comparing case and control groups, there was not significant difference in ECG changes in females, while there was a significant difference in males (14 of 20 versus 6 of 20) w ith considering that ECG changes in persons with MVP may be misdiagnosed as ischemic heart disease,it is recommended that cases (especially men) with MVP always keep a record of their ECGs.
Adalat Hosseinian , Firouz Amani , Ebrahim Hajizadeh , Shahram Habibzadeh ,
Volume 8, Issue 4 (Winter 2008)
Background & Objectives: Cardiovascular disease is the most important cause of death in the world. Statistics shows that mortality and morbidity from cardiovascular disease in Iran is going up, so quality of management and treatment of these patients need to be better. For these reasons, determination of survival rates and factors affecting it is important and is also the aim of this study.
Methods: This is a survival analytic prospective study, done on 800 patients, admitted in Ardabil Bouali Hospital CCU. All of the patients were followed up one year and a questionnaire about them was obtained. Statistical analysis was done with SPSS. For survival analysis Kaplan Maier, life table, logReng test and Cox regressions model were used.
Results: Mean age of patients was 60.6±12.4 years. Total number of mortality in one year was 84 persons (10.5%). 582 patients were men and 218 were women. 47.4% were smokers, 33.4% had hypertension, 18.1% had diabetes mellitus, 15.3% had hyperlipidemia and 30% had arrhythmia. Survival rate in the first 10 days, 28 days and one year were 94%, 93% and 90% respectively.
Conclusion: Factors that affected survival in Cox regress ional model were: diabetes mellitus, age, use of streptokinase, left ventricular ejection fraction, heart rate and heart block. Knowledge from survival rates and relative risks can help health managers in better health service preparation.
Saeid Nafisi , Seyed Shamsaddin Athari , Reza Kazemi , Ehsan Hosseini ,
Volume 9, Issue 4 (winter 2009)
Background and objectives: During the last years the effects of pulsative electromagnetic fields have been studied in the human and animals nervous system. The using of these fields in today living has caused worriment in safety of human. Stress causes very problems in behavior and function of biological systems. In this survey the effects of electromagnetic fields on stress behaviors of rats have been studied.
Methods: In this study we aimed to investigate the effects of electromagnetic fields with 700 milli Gauss currency produced by triangle electrical currents with low (10 Hz) and high (110 kHz) frequencies on stress behaviors in 60 adult, male Wistar rats. The rats were divided to two groups of control and test. The animals were exposed to the field for 80 minutes and in order to evaluate the possible effect of electromagnetic fields the Tail pinch (T.P.) test was conducted. The results were analyzed using statistical tests.
Results: Analyzing of the results of response time and stress behavior by T-test. In the group exposed electromagnetic fields of triangular low waves (10 Hz) for 80 min the results were meaningful (p < 0.05). The response and stressed behavior with this field is decreased very much. The results of two groups after 80 min under this field that have a difference in frequency showed that effects of frequency in behavior was meaningless.
Conclusion: The results of this study showed that electromagnetic fields produce anti-stress effect in rats. The radio waves (A.W) have higher effects.
Seyed Ahmad Mokhtari , Mitra Gholami , Mohammad Shakerkhatibi , Seyed Hamed MirHosseini,
Volume 10, Issue 3 (autumn 2010)
Background & Objectives: Arsenic is the third element of 5th Group of the periodic table and it is the twentieth rarest element in the earth's crust. This material has application in agriculture, livestock, medicine, electronics and metallurgy. It enters the environment from natural phenomena and human activities, causing pollution in it. Arsenic is a substance that is poisonous, cumulative, and an inhibitor of SH group enzymes. Several studies have identified significant correlation between high levels of Arsenic in drinking water and cancer in liver, nasal cavity, lungs, skin, bladder and kidney in men and women, and prostate in men. The present study was aimed to determin the impact of parameters affecting reverse osmosis membrane performance in Arsenic removal from drinking water.
Methods: In this research, Arsenic removal was surveyed and tested through reverse osmosis membrane with spiral-wound module (model: 2521 TE, made in CSM Co. Korea). The used solution was prepared synthetically in the laboratory using sodium arsenate, and system performance was investigated under the influence of parameters such as arsenic concentration, pressure, pH and temperature of the input solution. In each case, the flux rate passing through the membrane and transverse velocity was measured. For each mode, after 30 minutes, desired samples were picked up, and then were tested with silver diethyldithiocarbamate method (Test No. 3500-As B, standard method).
Results: The results of experiments and measurements showed that the parameters of concentration, pH, temperature and pressure in input solution are effective in reverse osmosis membrane performance (model TE 2521), and the increase or decrease in each parameter leads to changes in the system’s efficiency and performance. The optimal conditions and performance of membrane under the influence of these parameters were defined as follows: pressure 190-210 psi, concentration 0.2-0.5 mg/L, temperature 25-30 0C, and pH = 6-8. Arsenic removal efficiency at the optimum system performance was determined at about 99-95 percent.
Conclusion: According to the results and the high efficiency and acceptable performance, this approach is effective and can be applied as a method for Arsenic removal in areas with contaminated water.
Behzad Davarnia, Parvin Mehdipour , Morteza Arei, Seiyed Saeid Hosseini-Asl ,
Volume 12, Issue 2 (summer 2012)
Background & Objectives : Breast cancer is among the most frequent disorders among the world. BRCA1 gene was known as a tumor suppressor gene which its loss could be resulted in various destructions in genome. Therefore, changes occurred in its expression level could lead to increasing the effects of oncogene activity on breast cells.
Methods : RT-PCR and Q-RT-PCR were used for detecting BRCA1 expression status among 27 primary affected breast cancer patients. The association between its expression status and histopathologic data had been evaluated by statistical assays.
Results: Eighty-five percent of patients showed BRCA1 expression and this expression as well as its quantity had significant associations with tumor grade. It was found that tumors with low levels of BRCA1 expression tend to have higher grades.
Conclusion : BRCA1 has an important role in suppressing breast tumorogenesis. Corresponding to some of the previous reports, our findings revealed the role of decreasing in BRCA1 expression level as one of the factors which allows tumors to progress.
Hosein Douste Kami , Adalat Hosseinian , Effat Mazaheri, Naser Aslanabadi , Samad Ghaffari , Bahram Sohrabi , Eiraj Mohammadzadeh , Farhad Pourfarzi , Naser Moaiiednia ,
Volume 13, Issue 3 (autumn 2013)
Background & Objectives: Coronary bifurcation lesions are important, complex lesions with different therapeutic strategies. In this study, patients with Coronary bifurcation lesions were treated and clinical results in these patients were followed during the nine-month period.
Methods: This descriptive analytical study was performed between January 2007 to December 2008 at Tabriz Shahid Madani Cardiovascular Center. We have studied 96 patients (83 male and 13 female). Patients on the basis of one or two stents were placed in one group and the other groups were divided based on the use of Drug Eluting Stent and Bare Metal Stent. After diagnostic angiography if coronary bifurcation lesions were present based on Medina classification, appropriate angioplasty treatment was carried out. In a situations including chest pain, electrocardiographic changes or the objective evidence of ischemia and indication of angiography, appropriate diagnostic tests during follow up period were done. Clinical outcomes including acute coronary events were recorded. And result analyzed using SPSS version 16 . Chi-square ، Fisher and T tests were used to compare the relationship between variables.
Results: In this study 86.5% was male and 13.5% female. The mean age of these patients was 56±9.9 years old. The most prevalent risk factor was HTN with 41.7% incidence and 55.2% of patient had chronic stable angina and 26% of them had history of acute myocardial infarction, 7.2% with history of PCI and 5.2% with history Of CABGS. Most prevalent site of bifurcation was ALD/diagonal with 65.5% incidence. The most prevalent complication was mild bleeding from puncture site with 10.4% and 5.2% of patients had mild hematoma. Among patients with two stents versus one stent presence of AMI presentation with CSA, ST Elevation in ECG was statistically significant. Also involvement of SB (side branch) lesions lengths at SB, kissing ballooning after implantation of two stents were statistically significant. Among patients with DES versus BMS usage of stent in RCA, LAD, lesion lengths at PMB (proximal main branch), DMP (distal main branch) and SB, procedure time, radiation dose, fluoroscopy time were statistically significant. Among two groups MACE (major acute coronary event) in two stents patient between 1-3 month and total MACE at first 6 month were statistically significant
Conclusion: The age of patients treated with CBL was low, also more usage of BMS and stenting of BFLs with two BMS had weak results in this study but surprisingly total results of BMS and DES did not have significant difference after 9 months follow up between two groups.
Ali Niapour, Zahra Taghipour, Sahar Kiani, Fereshteh Karamali, Nazila Niapour, Mohammad Mehdi Mir Hosseini, Mohammad Reza Piri, Hosein Salehi, Noruz Najafzadeh, Mohammad Hosein Nasr-Esfahani ,
Volume 13, Issue 4 (Winter 2013)
Objective: Spinal cord injury (SCI) has become an especially challenging target in experimental neuroscience. Approach into the spinal cord is the interface among all different types of spinal cord injury modeling. The lower thoracic spinal cord has generated special interest due to the lower limbs’ spinal pattern generator position and presence of relative scales for behavioral assessment. However, a clear method with which to approach the thoracic spinal cord has yet to be determined.
Methods : A total of 20 animals were subjected to this study. Following induction of anesthesia, the 10th thoracic vertebra were positioned, and muscles were retracted. Using the high speed rotary, the vertebral lamina were carefully thinned. As a final point, the reduced lamina was meticulously removed away to expose underlying spinal cord. Loco motor behavioral test (BBB) was implemented before and after surgery procedure.
Results: This manuscript has presented the stepwise method to expose rat thoracic spinal cord. Whole procedure took less than an hour. Animals acquired complete BBB loco motor rating score before and after surgery indicating the safety of procedure.
Conclusion: This article introduces simple and practical approach for the rat lower thoracic spine. The anatomical orientation, anesthesia , postoperative management , and common problems are discussed .
Adalat Hosseinian , Vahideh Kasayi , Alireza Mohammadzade , Shahram Habibzadeh , Fariba Saghi , Mahnaz Davari , Azam Barzegar, Mehri Seyedjavadi ,
Volume 14, Issue 1 (spring 2014)
Background & Objectives : Nowadays, coronary artery disease is the most common cause of death in developed countries and in the whole world. According to the WHO reports, it will be the main cause of death in 2020. Myocardial infarction is the most common diagnosis among hospitalized patients in industrialized countries. This disease causes more mortality and morbidity than others. Coronary artery bypass grafting surgery (CABGS) is one of the common treatments for ischemic heart disease but it may have some complications. In this study we wanted to evaluate the incidence of CABGS complications in Imam Khomeini Hospital of Ardabil in the first month after CABG.
Methods: This study was a cross sectional analytic descriptive type and performed on all of the patients underwent CABGS in Imam Khomeini Hospital during 2011-2012. All of the data from patients (like demographic, past medical history, physical exam findings, paraclinical findings and CABGS complications) were inserted in special forms after gathering, and analyzed by SPSS v.16.
Results: In this study, 211 patients were studied. About 145 (68.72%) of them were male and 66 (31.28%) were female. Seventy patient (33.17%) were more than 70 years old. About 33.22% of patients had a history of cigarette smoking and 9.95% were opioid abused. The 34.12% of patients had hypertension (HTN) history, 40.28% diabetes mellitus (DM), 17.06% history of hyperlipidemia and 63.98% had a history of the previous MI. Chest pain was the most common complication among the patients (93.36%). According to our study the prevalence rate of post CABGS complications were: bleeding after surgery 13.27%, postoperative myocardial infection 8.05%, neurological disorders 12.32%, renal complications 2.36%, respiratory symptoms 11.37% and 34.59% for cardiovascular complications. Also the total mortality was 5 (2.36%) persons. The data analysis showed that there was a significant relationship between sex with survival status, local infection and neurological disorders, and also there was a significant relationship between age with post CABGS survival, bleeding after surgery and renal complications. There was also a significant relationship between DM and post CABGS survival, local infections and respiratory complications and between HTN and local infections.
Conclusion: According to the results of this study, the most common post CABGS complications were cardiovascular complications, especially arrhythmias.
Hashem Faal Moghanlo, Fatemeh Sadat Hosseini, Farzaneh Mikaili Manee,
Volume 14, Issue 3 (Autumn 2014)
Background & objectives : Different types of practises are known for improving motor skills in intellectually disabled boys. The purpose of this study was to compar e the impact of spark motor program and basketball on improving of gross motor skills in this people.
Methods: In this semi-experimental study , from 98 educable intellectually disabled students who studied in special school in Urmia, 30 children ( age range of 9 to 13 years and IQ mean 64.4 ) were selected objectively and divided in three groups (2 experimental and 1 control) based on pre - test. BOTMP was used as a measurement of motor ability. Selected motor program (Spark motor program) including strengthening training, games, sports and basketball techniques was performed for 24 sessions. T-tests (dependent) and co-variance were used to comparison of results.
Results: In Spark group after 24 sessions, there were significant effects on balance (p= 0.000), bilateral coordination (p=0.000) and strength (p=0.001). There was no significant effect in agility and speed (p= 0.343) in basketball techniques group after 24 sessions, there were significant effects in agility and speed (p= 0.001), balance (p= 0.000), bilateral coordination (p= 0.013) and strength (p= 0.007).
Conclusion: Based on the results of this study, it can be claimed that the Spark program and basketball techniques improve gross motor skills in educable intellectually disabled students. We also found a significant difference between the Spark program and basketball techniques efficacy on the improved skills. Furthermore, the efficacy of Spark program was significantly higher than basketball techniques (p<0.05).
Ali Hosein Zeinalzadeh , Raana Hosseini , Leila Abdullahi ,
Volume 15, Issue 1 (spring 2015)
Background & objectives: Cancer is a major public health problem in many countries of the world. At the present time, cancer is the third leading cause of death in developing countries. The aim of this study was to determine of epidemiologic status and incidence rates of cancers in the patients above 15 years old in East Azerbaijan province , Iran.
Methods: This cross-sectional study was performed on 3832 new cancer cases were obtained from cancer registries in East Azerbaijan province in 2012. Characteristics of all registered cancers (including age, sex, and etc) were collected in a special form. Then the data were summarized and coded using the International Classification of Disease (ICD). Frequency, mean, standard deviation and 95% confidence interval of the study variables were calculated. Age standardized incidence rate was performed by direct method using the world standard population. The data was analyzed by SPSS 16 software.
Results: Among 3832 cases, 2047(53.5%) were males and 1782 (46.5%) were females. The mean age and standard deviation of cancer incidence were 58.1 and 15.8 years, respectively. The overall incidence rate of all types of cancer in population was 132.5 in 100000 people per year. Among men, the highest frequency (263) of all cancers occurred in the 65-69 age group but in women the highest (220) of them occurred in the 50-54 age group. The highest incidence rate (813.3 per 100000) of cancers had occurred in men who were older than 85 years. While the highest (406.3 per 100000) of them in women had occurred in 70-74 years. The most common cancers among males and females were stomach (11.4%) and breast (30%), respectively. Histopathologically the most common cancers of stomach, breast and skin were adenocarcinoma, infiltrating duct carcinoma and basal cell carcinoma, respectively.
Conclusion: According to the results, the most common cancers in East Azerbaijan province were breast and stomach, respectively. Therefore, comprehensive and complementary studies for recognizing relevant factors seem to be essential.
B Zamani, M Azari, A Hosseinian , A Shokrdargahy, A Mardi , Sh Azari,
Volume 15, Issue 2 (summer 2015)
Background & objectives: Myocardial infarction (MI) isone of the most commonly heart diseases in all countries with the mortality rate of about 30%. Reperfusion of blocked coronary arteries plays an important role in reducing mortality and enhancing the quality of life of patients after acute MI.
Methods: This clinical trial is to compare the efficacy of streptokinase administered intravenously in a two slow and accelerated groups: control group (slow intravenous infusion during 1 hour) and case group (half-hour accelerated intravenous infusion of streptokinase) with the sample size of 100 patients (divided randomly to 50 patients in each group). The data tool was a questionnaire, included the collected ECG changes before and after echocardiography and laboratory tests of patients. Data analyzed with SPSS software using chi-square test.
Results:After reperfusion of the coronary artery, in the both case and control groups, elevation of ST segment has decreased statistically in two groups (60% and 84%, respectively). The complications rate following injection of SK in both case and control groups were 46% and 56%, respectively. The fraction in which 30% and 38% belong to cardiac complications, 32% and 22% to allergic symptoms and hematologic effects were 32% and 22%, in two groups, respectively and there was no statistically significant difference between two groups.
Conclusion:According to the results of this study the accelerated (30 minutes) SK infusion can be fruitful for improving coronary reperfusion in patients with MI.
A Gomar, A Hosseini , N Mirazi, M Gomar,
Volume 15, Issue 3 (autumn 2015)
Background & objectives: Hyoscine (scopolamine) as an anticholinergic and antinociceptive drug, has some side effects. Recently, it has been received much attention to the interactions between synthetic drugs and herbal extracts and their pharmacological responses which made the possibility of using the minimum dose and low side effects. In this study, we evaluated the effect of Salvia officinale extract, hyoscine and their combinationin management of pain in rats.
Methods: In this experimental study animals were divided randomly into eight groups (n=6). Hyoscine (0.5, 1 and 5 mg/kg) administrated by intraperitoneal injection and extract (100 and 200 mg/kg) was administered by gavages one hour before administration of hyoscine. Thirty minutes after treatment, rats were subjected to tail-flick test and data were recorded. Statistical significance was considered at p<0.05.
Results: Administration of hyoscine at doses of 0.5, 1 and 5 mg/kg created significant analgesic effects compared to control group in the Tail-flick test (p<0.05, p<0.01 and p<0.05, respectively). The combination of S.officinale extract (100 and 200 mg/kg) and hyoscine (1 mg/kg) significantly increased the pain threshold than the groups receiving only extract or hyoscine.
Conclusion: Our data showed that hydroethanolic extract of Salvia officinale has an important antinociceptive effect which can lead to decreased pain in rats. Sincehyoscine as an analgesic drug has some side effects, combination of Salvia officinale extractand hyoscine can decrease the needed dose of hyoscine and itsside effects.
Ebrahim Hosseini, Zahra Zia,
Volume 16, Issue 1 (spring 2016)
Background & objectives: The teratogenic effects of electromagnetic radiation on different processes of growth caused many concerns related to the harmful effects of cell-phone radiation on human health. Therefore, the aim of this study was to investigate the effects of cell-phone radiation on estrogen, progesterone, FSH and LH hormones together with dynastic sexual cells of adult female offspring of pregnant rats affected by these radiations.
Methods: In this experimental study, 24 pregnant female rats divided into 3 groups including the control, sham and experimental groups were used. The control group received no radiation and the experimental group was exposed to cell-phone radiation at the beginning of pregnancy (4 hours daily for 14 days). The control group was exposed around turning-on cell-phone without conversation over the same period. After giving birth and after maturity, 10 female offsprings of different groups separated and after phlebotomizing, sexual hormones levels was measured and by separating the ovaries, ovarian follicles species were counted. The results analyzed using ANOVA and T tests. Differences in statistical analysis of data were considered significant at p<0.05.
Results: The results showed that the pregnant female exposure to cell-phone radiation caused significant increase in the size and weight of the ovaries and atresic follicles (p<0.05) without significant effect on the number of primary and secondary follicles, antral, graph, primordial, corpus luteum and sexual hormones.
Conclusion: Exposure to cell-phone radiations caused increase in the size, weight and atresic follicles of offspring’s ovaries in pregnant females
Tooba Karimizadeh Moneh, Ebrahim Hosseini,
Volume 16, Issue 3 (autumn 2016)
Background & objectives: Ritalin is one of the drugs used in the treatment of attention-deficit/hyperactivity disorder (ADHD). This study aimed to investigate the comparative effect of Ritalin with grape seed extract on passive avoidance learning in adult male rats.
Methods: In this experimental study, 40 adult male Wistar rats divided randomly into 5 groups of 8 rats including control, sham and three experimental groups. The control group received no treatment. The sham group received 1 ml of distilled water per day. At the same time the experimental groups received 100 mg/kg grape seed extract, 1 mg/kg Ritalin or 100 mg/kg grape seed extract together with 1 mg/kg of Ritalin by gavage for 28 days. For measuring the amount of avoidance learning, Shuttle box was used. Data analyzed by ANOVA and consistent Tukey's tests using SPSS-18 software and p>0.05 considered as significant.
Results: The results showed that Ritalin decreases the passive avoidance learning, while the grape seed extract alone or together with Ritalin increases passive avoidance learning.
Conclusion: The outcome of this research shows that taking Ritalin leads to decreasing passive avoidance learning. However, the simultaneous taking Ritalin with grape seed extract inhibits the Ritalin effect and increasing the learning.