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Showing 2 results for Bakhshi

Hosein Noug , Ali Khodadadi, Hamid Bakhshi ,
Volume 4, Issue 1 (spring 2004)
Abstract

  Background &Objective: Infarctian size is the most important prognostic factor in patients with acute myocardial infarction (AMI). Reperfusion therapy using thromboliatics is the most important measure in order to limit the infarction, size. Infarction size on the other hand, associates directly with left ventricular (LV) function. The presence of Q wave on electrocardiogram (ECG) after thrombolytic therapy is associated with increased mortality during first months after AMI. Moreover electrocardiographic changes after thrombolytic therapy can predict LV function. This study is an attempt to evaluate the relationship between electrocardiographic Q wave and LV function after thrmobolytic therapy in patients with MI.

  Methods: 176 patients with first episode of AMI (diagnosed based on WHO criteria) who were receiving streptokinase took part in this analytical study. ECG of the first day after admission and ECG of discharge day (usually the sixth day) were evaluated in terms of the presence of pathologic Q wave. LV function was evaluated by Echocardiography using Simpson method. The data were analyzed by SPSS program using chi-square test.

  Results: On discharge day 82.4% of the patients had pathologic Q wave and 17.6% were without it. 51.6% of patients without pathologic Q wave, had normal LV function (LVGF>55%) while 26.9% of them had Q wave (p= 0.001). 73.3% of males and 56.4% of females had Q wave on ECG.

  Conclusions: Presence of Q wave on ECG in patients with AMI after thrombolytic therapy correlates with LV function and indicates impaired LV function in these patients.


Shadi Shahsavan, Abdolaziz Rastegar Lari , Bita Bakhshi, Parviz Owlia, Maliheh Nobakht ,
Volume 16, Issue 3 (autumn 2016)
Abstract

Background & objectives: Shigella spp. are gram negative bacteria that can cause shigellosis in human. It is important in young children as well as elderly and immunocompromised people. Threatening complications can occur in severe cases with multidrug resistance species. It has been observed that Shigella spp. have become resistant to antibiotics like other bacteria. Investigation of resistance to azithromycin, tetracycline and pattern of resistance are the objectives of this study.

Methods: Fifty isolates of Shigella spp. which have been collected from three hospitals in Tehran were studied. Isolates identified and confirmed as Shigella spp. by biochemical, serological and molecular methods (ipaH, wbgz, rfc genes). Antimicrobial susceptibility test was performed for ampicillin, azithromycin, ciprofloxacin, doxycycline, levofloxacin, minocycline, nalidixic acid, norfloxacin, streptomycin, trimethoprim-sulfamethoxazole and tetracycline by disc agar diffusion method. Minimal inhibition concentrations were performed for azithromycin and tetracycline.

Results: From a total of 50 Shigella spp. isolates, 16% of them were Shigella flexneri and 84% Shigella sonnei. The majority of isolates were multidrug resistant. The most resistance was seen to doxycycline, streptomycin, trimethoprim-sulfamethoxazole and tetracycline. Resistance to azithromycin was 6%  and all of the isolates were susceptible to norfloxacin and levofloxacin. Nine patterns of resistance were revealed to these isolates.

Conclusion: High resistance to tetracycline was observed and resistance to azithromycin as an alternative treatment choice was also considerable.



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مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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