[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 14, Issue 3 (Autumn 2014) ::
J Ardabil Univ Med Sci 2014, 14(3): 285-291 Back to browse issues page
Prevalence of Extended-Spectrum Beta Lactamase in Entrobacteriaceae Isolated from Urinary Tract Infections in Ardabil, Iran
Masoumeh Akbari, Noor Amir Mozaffari, Hadi Peeri Dogaheh
Abstract:   (9458 Views)

  Background & objectives: Urinary tract infections (UTIs) caused by extended-spectrum beta lactamase (ESBL)-producing bacteria have become a growing problem worldwide. The aim of this study was to investigate the prevalence of ESBL-producing bacteria in urine samples of hospitalized patients in Imam Khomeini hospital of Ardabil over a period of October 2011 to August 2012.

  Methods : A total of 400 urinary pathogens isolated from urine samples were included in the study. All isolates were identified by routine biochemical methods and antimicrobial susceptibility testing carried out by Kirby-Bauer method. Confirmatory test for production of ESBLs was performed by the combination disk tests. The results were interpreted according to the recommendation of CLSI.

  Results : Of 400 isolated bacteria, 267 were E.coli, 39 Klebsiella pneumoniae, 17 Klebsiella oxytoca, 16 Enterobacter cloacae, 15 Enterobacter aerogenese, 6 Enterobacter agglomerans, 8 Enterobacter sakazakji, 3 Citrobacter froundi, 2 Citrobacter diversus, 3 Proteus mirabilis, 4 Edvardsiella tarta, 3 Serratia marcesecens and 17 Morganella morganii all of which then were analyzed. ESBL was detected in 36.75% (147) of isolates. Eighty nine E.coli cases (77.4%), 15 Klebsiella pneumonia (13.04%), 2 Klebsiella oxytoca (1.74%), 3 Enterobacter aerogenese (2.6%), 4 Enterobacter cloacae (3.5%), 1 Citrobacter ferundi (0.86%), and 1 Morganella morganii (0.86%) were detected as ESBLs producers, respectively.

  Conclusion : Based on the results of this study, broad-spectrum beta-lactamase production in bacterial strains isolated from patients with urinary tract infection was very high and almost 40% of all bacterial species isolates were ESBLs producers. Because of the high prevalence of ESBL-producing bacteria in the urinary tract infections in hospitalized patients of our area, we would strongly suggest that the ESBL production should be considered in these patients.

Keywords: Extended-Spectrum Beta-Lactamase (ESBL), Entrobacteriaceae, Urinary Tract Infections, Disk Diffusion
Full-Text [PDF 148 kb]   (2628 Downloads)    
Type of Study: article | Subject: Special
Received: 2013/11/11 | Accepted: 2014/09/13 | Published: 2014/09/29
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Akbari M, Amir Mozaffari N, Peeri Dogaheh H. Prevalence of Extended-Spectrum Beta Lactamase in Entrobacteriaceae Isolated from Urinary Tract Infections in Ardabil, Iran. J Ardabil Univ Med Sci. 2014; 14 (3) :285-291
URL: http://jarums.arums.ac.ir/article-1-694-en.html


Volume 14, Issue 3 (Autumn 2014) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
Persian site map - English site map - Created in 0.1 seconds with 32 queries by YEKTAWEB 3986