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:: Volume 10, Issue 1 (spring 2010) ::
J Ardabil Univ Med Sci 2010, 10(1): 7-13 Back to browse issues page
C - Reactive Protein as a Diagnostic Marker in Pleural Effusion
Mahin Jamshidi Makiani , Seiyed Abdollah Moosavi, Farshid Abedi, Shafei Rahimi, Elham Goodarzi
Abstract:   (4903 Views)

  Background & Objectives : One of the first steps in diagnosis of pleural effusion is distinction between exudative and transudative types. The aim of this study was to assess C – reactive protein (CRP) level as one of the diagnostic marker for differentiation of exudative from transudative pleural effusions.

  Methods : In this descriptive and sectional study, 80 patients with confirmed pleural effusion were assessed. These patients were divided into two groups based on Light´s criteria. Serum and pleural CRP were measured with Latex Agglutination Test.

  Results : Out of 80 patients with pleural effusion 26 were transudative (32.5%) and 54 were exudative (67.5%). In exudative group, 72.2% of cases were CRP positive (1+ to 3+), and in transudative group, only 38.5% of cases were CRP positive (p < 0.05). There was no significant differences between different exudative pleural effusion etiologies (infectious and non infectious, malignant and non malignant and tuberculosis) and the number of CRP positive cases (p > 0.05). The rate of CRP positivity in exudative pleural effusion group was more than transudative group (p < 0.05).

  Conclusion: According to our study it seems that CRP criterion could help in distinction between exudative and transudative types of pleural effusion.

Keywords: CRP; Pleural Effusion; Exudative; Transudative
Full-Text [PDF 136 kb]   (1418 Downloads)    
Type of Study: article | Subject: Special
Received: 2009/06/3 | Accepted: 2010/05/18 | Published: 2010/06/29
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Jamshidi Makiani M, Moosavi S A, Abedi F, Shafei Rahimi, Goodarzi E. C - Reactive Protein as a Diagnostic Marker in Pleural Effusion . J Ardabil Univ Med Sci. 2010; 10 (1) :7-13
URL: http://jarums.arums.ac.ir/article-1-229-en.html


Volume 10, Issue 1 (spring 2010) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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